UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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Soliciting Material Pursuant to Section 240.14a-12

 

AMGEN INC.

(Name of Registrant as Specified in Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

 

 

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LOGOLOGO

1


 

Robert A. Bradway

Chairman of the Board,

Chief Executive Officer and President

 

LOGOLOGO

 
 

Amgen Inc.

One Amgen Center Drive

Thousand Oaks, CA 91320-1799

April 7, 20205, 2022

Dear Fellow Stockholder:

You are invited to attend the 20202022 Annual Meeting of Stockholders, or Annual Meeting, of Amgen Inc. to be held on Tuesday, May 19, 2020,17, 2022, at 11:00 A.M., Pacific Time.Time, via the internet at www.virtualshareholdermeeting.com/AMGN2022.

Our Mission:Mission: We seek to develop innovativemedicinesinnovativemedicines that address important unmet medical needs in the fight against serious illness. This mission is the central underpinning of our strategy, inherently long-term, and in service of patients and their families.

Our Heritage:This month,mission to serve patients is supported by our long-standing focus on using our resources responsibly to support the sustainability of our business and the global environment in which we are celebratingand our fortieth anniversary. Entrepreneurs started Amgen 40 years ago knowing that biotechnology could change lives. Today, our innovative medicines can be found in approximately 100 countries. We are proud of what Amgen has accomplished in the past four decades, and excited for what the future holds.patients live.

Execution of Our Strategy: In 2019,2021, we advanced key facetshave remained focused on our strategic priorities while navigating the ongoing impact of the pandemic. Innovation is at the core of our long-term growth strategy in a year of transition.strategy. We have reshaped our portfolio of innovativelaunched three medicines in recent years, focusing on products that can grow primarily through volume increases, rather than price increases, includingaddress serious diseases – RepathaLUMAKRAS®,for the treatment of advanced non-small cell lung cancer, AimovigTEZSPIRE®,Prolia®(1),EVENITY® for the treatment of severe asthma, and most recently,an expanded indication for Otezla® for the treatment of plaque psoriasis across all severities (mild, moderate, and severe). LeveragingWe completed strategic business acquisitions that complement our industry-leading biologics manufacturing skills, we have delivered our first biosimilars to the U.S. market,internal innovation, including MVASI®Five Prime Therapeutics, Inc. (biosimilar bevacizumab (Avastin®)) andKANJINTIbemarituzumab®, a first-in-class antibody in oncology, and Teneobio, Inc. (biosimilar trastuzumab (Herceptin®)),and its proprietary bispecific and multispecific antibody technologies and portfolio of early-stage oncology assets. We entered into a collaboration with Kyowa Kirin Co. Ltd. to develop and commercialize AMG 451, a Phase 3-ready first-in-class asset in 2019 (addinginflammation. Additionally, we invested to strengthen our two successful biosimilar launches outside of the U.S. last year). Wediscovery capabilities, progressed our early oncologyinnovative pipeline, continued to advance our biosimilar programs includingAMG 510,(with 11 biosimilars in our KRASG12C small molecule inhibitor, that has enrolled a potentially pivotal Phase 2 monotherapy studycurrent portfolio) and expand our global presence, including in advancednon-small cell lung cancer, began enrollment of colorectal cancer patientsfast-growing markets in a Phase 2 monotherapy study, and is also being investigated as a treatment for a variety of other solid tumors. Outside of oncology,Asia. Throughout, we have also advanced our pipeline in our other therapeutic areas and await data fromtezepelumab for allergic andnon-allergic asthma,omecamtiv mecarbil for heart failure, and Otezla for mild to moderate psoriasis. And we are increasingly well-positioned to take advantage of the growing demand for innovative healthcare globally, with our expanding presence in markets around the world, including China, where we have entered into a strategic oncology collaboration withBeiGene Ltd., and Japan. In 2019, we also continued to work on the construction of our second next-generation manufacturing facility in Rhode Island, building on the success we have had with our first next-generation facility in Singapore; delivering the same output as a traditional plant, but with a much smaller environmental footprint. We continue to maintainmaintained a disciplined approach to capital allocation, through which we investinvesting in our future while alsoconcurrently returning capital to stockholders. In the Compensation Discussion and Analysis section of this proxy, we further discuss our progress against our strategy in 2019.

Our Commitment to Society:As we striveOur approach to bring to marketfirst-in-class orbest-in-class medicines to treat serious illness and deliver a large effect size, we believe that we are bringing the type of innovation that can address the challenges of our increasingly older and more urban global population. How we achieve this aspiration is equally important since making a positive difference in the world is at the heart of what we do. As part of our mission to serve patients, we take our responsibilities seriously with respect to the areas of environmental sustainability, social responsibility, and corporate governance, (ESG)or ESG, begins with our mission to serve patients and is supported by our long-standing focus on using resources responsibly to support the sustainability of our business. In 2021, we launched a new environmental sustainability plan, our third since 2007, that includes a target of achieving carbon neutrality in our operations by 2027 (while also aiming to further reduce our water use by 40% and waste disposed by 75%(2)). In additionOur latest U.S. biomanufacturing plant featuring innovative technologies in Rhode Island received U.S. Food and Drug Administration approval in January 2022, expanding our manufacturing capacity while also delivering environmental and cost efficiencies. We announced plans to a commitmentinvest approximately $1 billion to ethical business practices,build two additional U.S. plants (in Ohio and North Carolina) featuring innovative technologies that support our ESG efforts include integrating environmentally sustainable practices throughout our business, improving2027 environmental sustainability plan. Since its inception, the Amgen Foundation has contributed more than $375 million to non-profit organizations around the world that complement Amgen’s purpose-driven dedication to impacting lives in inspiring and innovative ways, including through four signature science education programs that, in 2021 alone, have reached over 27 million students and educators worldwide. Through patient assistance programs, expanded access to investigational therapies, donations, and other initiatives, we have developed patient support programs to assist eligible patients around the world to obtain the medicines they need. We increased our medicines, supporting science education for the next generation of innovators,focus on diversity, inclusion, and enhancingbelonging, including by working to improve the diversity and inclusivenessrepresentation of racial and ethnic minority populations in clinical trial research and we aspire to double our workforce.supplier diversity spending and triple our Black-owned business spend in the U.S. by 2023.(3) Our new U.S. plant locations in Ohio and North Carolina were chosen, in part, because they will expand our access to diverse talent.

Stockholder Engagement:We are alsocontinue to be guided by the perspectives of our stockholders as expressed through their direct engagement with us throughout the year and at our Annual Meeting. SinceConsistent with prior years’ practices, since our 20192021 annual meeting of stockholders, in addition to outreach by our executives and Investor Relations department to investors owning approximately 58% of our outstanding shares, we have engaged in governance-focused outreach activities and discussions with the governance teams for stockholders comprising approximately 51%52% of our outstanding shares. Topics discussed includedIn 2021, stockholders asked questions about our business performance,response to COVID-19 and ESG issues. In response to stockholder feedback, we have enhanced our ESG programs,reporting, including disclosing our annual Consolidated EEO-1 Report(4) and executive compensation (including its direct link toadditional metrics on the diversity of our strategy).workforce. Feedback received during the course of these meetingsactivities is shared with the fullour Board of Directors and informs Board decisions. In addition to these governance-focused outreach activities, we have more than doubled our participation in investor events and committee decisions.engagement sessions since 2017. We are eager to continue this valuable dialogue with our investors in the coming year.

We are grateful to our former Executive Vice President and Chief Financial Officer, David W. Meline, who retired as CFO at the end of 2019 for his significant and lasting contributions to Amgen. Peter H. Griffith joined us as our new CFO this year and his extensive financial and operational experience will benefit Amgen as we continue our efforts to serve more patients and drive long-term growth and stockholder value.

I look forward to sharing more about our Company at the Annual Meeting. In addition to the business to be transacted and described in the accompanying Notice of Annual Meeting of Stockholders, I will discuss recent developments during the past year, the substantial progress we made on our strategic priorities for 2019,in 2021, and respond to comments and questions.

On behalf of our Board, of Directors, I thank you for your participation and investment in Amgen. We look forward to the Annual Meeting on May 19. As a final note, and also on behalf of our Board of Directors, I would like to thank Rebecca M. Henderson, who is not standing forre-election this year, for her decade of wise counsel to and guidance of Amgen.17.

Sincerely,

 

LOGO

Robert A. Bradway

Chairman of the Board,

Chief Executive Officer and President

(1)

Being developed in collaboration with AstraZeneca plc.

(2)

Carbon neutrality goal refers to Scope 1 and 2 emissions. Reductions take into account only verified reduction projections, and do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

(3)

Measured against a 2019 baseline.

(4)

Beginning with our Consolidated EEO-1 Report filed in 2021.


Amgen Inc.

One Amgen Center Drive

Thousand Oaks, California 91320-1799

Notice of Annual Meeting of Stockholders

To be Held on May 19, 202017, 2022

 

To the Stockholders of Amgen Inc.:

 

Date and Time: 

Tuesday, May 19, 2020,17, 2022, at 11:00 A.M., Pacific Time

Location: 

After careful consideration, in light of the on-going developments related to the COVID-19 pandemic and governmental decrees that in-person gatherings be postponed or canceled, and in the best interests of public health and the health and safety of our stockholders, Board of Directors, and employees, our 2020Our 2022 Annual Meeting of Stockholders, or Annual Meeting, will be held solely by remote communication via the internet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. YouWhile you will not be able to attend the Annual Meeting in person.person, stockholders will, to the extent possible, be afforded the same rights and opportunities to participate at the virtual meeting similarly to how they would participate at an in-person meeting.

 

Stockholders or their proxyholders may participate, vote, and examine our list of stockholders at our Annual Meeting via the Internetinternet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022 and using your control number.

Record Date: 

March 20, 2020.18, 2022. Amgen stockholders of record at the close of business on the record date are entitled to receive notice of, and vote at, the Annual Meeting and any continuation, postponement, or adjournment thereof.

Mail Date: 

We intend to mail the Notice Regarding the Availability of Proxy Materials, or the proxy statement and proxy card, as applicable, on or about April 7, 2020,5, 2022, to our stockholders of record on the record date.

Items of Business:
 1. 

To elect 1112 directors to the Board of Directors of Amgen for a term of office expiring at the 20212023 annual meeting of stockholders. The nominees for election to the Board of Directors are Dr. Wanda M. Austin, Mr. Robert A. Bradway, Dr. Brian J. Druker, Mr. Robert A. Eckert, Mr. Greg C. Garland, Mr. Fred Hassan, Mr. Charles M. Holley, Jr., Dr. S. Omar Ishrak, Dr. Tyler Jacks, Ms. Ellen J. Kullman, Ms. Amy E. Miles, Dr. Ronald D. Sugar, and Dr. R. Sanders Williams;

 2. 

To hold an advisory vote to approve our executive compensation;

 3. 

To ratify the selection of Ernst & Young LLP as our independent registered public accountants for the fiscal year ending December 31, 2020;2022; and

 4.

To consider one stockholder proposal, if properly presented at the Annual Meeting; and

5. 

To transact such other business as may properly come before the Annual Meeting or any continuation, postponement, or adjournment thereof.

 

Attendance: The live audio webcast of the Annual Meeting will begin promptly at 11:00 A.M., Pacific Time. To participate in the virtual meeting, you will need the control number included on your Notice, proxy card, or voting instruction form. We encourage you to access the meeting prior to the start time. Please read “INFORMATION CONCERNING VOTING AND SOLICITATION—“Information Concerning Voting and Solicitation—Attendance at the Annual Meeting” in the accompanying proxy statement.

Voting:Your vote is important, regardless of the number of shares that you own. Whether or not you plan to attend the Annual Meeting, it is important that your shares be represented and voted. Please read the Notice of Annual Meeting of Stockholders and proxy statement with care and follow the voting instructions to ensure that your shares are represented. By submitting your proxy promptly, you will save the Company the expense of further proxy solicitation. We encourage you to submit your proxy as soon as possible by Internet,internet, by telephone, or by signing, dating, and returning all proxy cards or instruction forms provided to you.

By Order of the Board of Directors

 

 

LOGOLOGO

Jonathan P. Graham

Secretary

Thousand Oaks, California

April 7, 20205, 2022


    

 

 

 

 

Table of Contents

 

 

 

 

 

Table of Contents

 

41

Our Strategy

  41

39Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance

43

Our Compensation and Governance Best Practices

  44

40Executing on Our Strategic Priorities While Navigating the Impact of the COVID-19 Pandemic

45

Aligning Pay With Performance and Execution of Our Strategic Priorities

  

41

45

Positive 20192021 Say on Pay Vote Outcome and Engagement With Our StockholdersCompensation Design Changes in Response to 2021 Stockholder Input

  

46

51

Long-Term Incentive Equity Award Design in 20192021

  

46

52

Our 20192021 Compensation Program Highlights and Objectives

  

47

53

How Compensation Decisions Are Made For Our Named Executive Officers

  

48

54

Elements of Compensation and Specific Compensation Decisions

  

51

57

Compensation Policies and Practices

  

61

68

Non-Direct Compensation and Payouts in Certain Circumstances

  

63

70

TaxesTax and Accounting Standards

  

65

72

Executive Compensation Tables

  

66

73

Director Compensation

  

83

87

Security Ownership of Directors and Executive Officers

  

87

91

Security Ownership of Certain Beneficial Owners

  

89

93

Item 3—Ratification of Selection of Independent Registered Public Accountants

  

90

94

Audit Matters

  

91

95

Annual Report on Form10-K

  

92

96

Item 4—Stockholder Proposal to Require an Independent Board Chair

93

Certain Relationships and Related Transactions

  

96

97

Information Concerning Voting and Solicitation

  

97

98

Other Matters

  

101

102

Appendix A: Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations

  

A-1

Appendix B: Reconciliations of GAAP toNon-GAAP Measures

  

B-1

 

 

LOGO  ï 20202022 Proxy Statement


Proxy Statement Summary

Proxy Statement Summary

This summary contains highlights about our Company and the upcoming 2020 Annual Meeting of Stockholders, or Annual Meeting. This summary does not contain all of the information that you should consider in advance of the meeting and we encourage you to read the entire proxy statement before voting.

2020 Annual Meeting of Stockholders

Date and Time:

Tuesday, May 19, 2020, at 11:00 A.M., Pacific Time

Location:

After careful consideration, in light of the on-going developments related to the COVID-19 pandemic and governmental decrees that in-person gatherings be postponed or canceled, and in the best interests of public health and the health and safety of our stockholders, Board of Directors, and employees, our 2020 Annual Meeting of Stockholders will be held solely by remote communication via the internet atwww.virtualshareholdermeeting.com/AMGN2020. You will not be able to attend the Annual Meeting in person.

Stockholders or their proxyholders may participate, vote, and examine our list of stockholders at our Annual Meeting via the Internet atwww.virtualshareholdermeeting.com/AMGN2020 and using your control number.

Record Date:

March 20, 2020

Mail Date:

We intend to mail the Notice Regarding the Availability of Proxy Materials, or the proxy statement and proxy card, as applicable, on or about April 7, 2020, to our stockholders.

Voting Matters and Board Recommendations

  Matter

Our Board Vote Recommendation    

  Management Proposals:

  Item 1:

Election of the 11 Nominees to the Board of Directors Named in This Proxy Statement (page 9)

FOR each Director Nominee

  Item 2:

Advisory Vote to Approve Our Executive Compensation (page 34)

FOR

  Item 3:

Ratification of Selection of Independent Registered Public Accountants (page 90)

FOR

  Stockholder Proposal:

  Item 4:

Stockholder Proposal to Require an Independent Board Chair, if properly presented (page 93)

AGAINST

LOGOï 2020 Proxy Statement    1


    

 

 

 

 

Proxy Statement Summary

 

 

 

 

 

Proxy Statement Summary

This summary contains highlights about our Company and the upcoming 2022 Annual Meeting of Stockholders, or Annual Meeting. This summary does not contain all of the information that you should consider in advance of the meeting and we encourage you to read the entire proxy statement before voting.

2022 Annual Meeting of Stockholders

Date and Time:

Tuesday, May 17, 2022, at 11:00 A.M., Pacific Time

Location:

Our 2022 Annual Meeting of Stockholders will be held solely by remote communication via the internet at www.virtualshareholdermeeting.com/AMGN2022. While you will not be able to attend the Annual Meeting in person, stockholders will, to the extent possible, be afforded the same rights and opportunities to participate at the virtual meeting similarly to how they would participate at an in-person meeting.

Stockholders or their proxyholders may participate, vote, and examine our list of stockholders at our Annual Meeting via the internet at www.virtualshareholdermeeting.com/AMGN2022 and using your control number.

Record Date:

March 18, 2022

Mail Date:

We intend to mail the Notice Regarding the Availability of Proxy Materials, or the proxy statement and proxy card, as applicable, on or about April 5, 2022, to our stockholders.

Voting Matters and Board Recommendations

  Matter

Our Board Vote Recommendation    

  Management Proposals:

  Item 1:

Election of the 12 Nominees to the Board of Directors Named in This Proxy Statement (page 8)

FOR each Director Nominee

  Item 2:

Advisory Vote to Approve Our Executive Compensation (page 40)

FOR

  Item 3:

Ratification of Selection of Independent Registered Public Accountants (page 94)

FOR

How to Vote

 

 

LOGO

 

   By Internet: You may submit a proxy over the Internetinternet by following the instructions on the website referred to in the Notice, proxy card, or voting instruction form mailed to you. You will need the control number that appears on your Notice, proxy card, or voting instruction form.

 

LOGO

 

   By Telephone: You may submit a proxy by telephone by following the instructions on the website referred to in the Notice, proxy card, or voting instruction form mailed to you. You will need the control number that appears on your Notice, proxy card, or voting instruction form.

 

LOGO

 

   By Mail:If you received a full paper set of materials, date and sign your proxy card or voting instruction form and mail it in the enclosed, postage-paid envelope. If you received a Notice, you may request a proxy card by following the instructions on your Notice. You do not need to mail the proxy card if you are submitting your proxy by Internetinternet or telephone.

 

LOGO

 

   At the Meeting:To vote at the Annual Meeting, visitwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. You will need the control number that appears on your Notice, proxy card, or voting instruction form.Please note that if your shares are held of record by a broker, bank, trust, or other nominee, and you decide to attend and vote at the Annual Meeting, your vote in person at the Annual Meeting will not be effective unless you provide a legal proxy, issued in your name from the record holder (your broker, bank, trust, or other nominee). Please read “INFORMATION CONCERNING VOTING AND SOLICITATION—“Information Concerning Voting and Solicitation—Attendance at the Annual Meeting.” Even if you intend to attend the Annual Meeting, we encourage you to submit your proxy in advance of the Annual Meeting.

 

2    LOGO  2020ï 2022 Proxy Statement1


    

 

 

 

 

Proxy Statement Summary

 

 

 

 

 

Item 1: Election of 1112 Nominees to the Board of Directors (Page 9)8)

 

  

  Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive    

Compensation

and

Management

Development

 

 

 

 

   

Equity

Award

 

 

  

 

 

 

Corporate  

Responsibility  

and  

Compliance  

 

 

 

  Wanda M. Austin

 

   

 

 

 

 

   

 

65

 

 

 

   

 

2017

 

 

 

   

 

M

 

 

 

       

 

M

 

 

 

    
 

 

  Robert A. Bradway

 

     

 

57

 

 

 

   

 

2011

 

 

 

       

 

C

 

 

 

     

 

M

 

 

 

  
 

 

  Brian J. Druker

 

   

 

 

 

 

   

 

64

 

 

 

   

 

2018

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Robert A. Eckert

 

   

 

 

 

 

   

 

65

 

 

 

   

 

2012

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

   

 

C

 

 

 

    
 

 

  Greg C. Garland

 

   

 

 

 

 

   

 

62

 

 

 

   

 

2013

 

 

 

     

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

    
 

 

  Fred Hassan

 

   

 

 

 

 

   

 

74

 

 

 

   

 

2015

 

 

 

   

 

M

 

 

 

       

 

M

 

 

 

    
 

 

  Charles M. Holley, Jr.

 

   

 

 

 

 

   

 

63

 

 

 

   

 

2017

 

 

 

   

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

      
 

 

  Tyler Jacks

 

   

 

 

 

 

   

 

59

 

 

 

   

 

2012

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Ellen J. Kullman

 

   

 

 

 

 

   

 

64

 

 

 

   

 

2016

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

        
 

 

  Ronald D. Sugar

 

   

 

 

 

 

   

 

71

 

 

 

   

 

2010

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

       

 

C

 

 

 

  

 

  R. Sanders Williams

 

   

 

 

 

 

   

 

71

 

 

 

   

 

2014

 

 

 

        

 

M

 

 

 

                  

 

M

 

 

 

“C”

indicates Chair of the committee.

“M”

indicates member of the committee.

LOGO

Director*Current Composition of the Board and Corporate Governance Highlights

 

 

LOGO

*

For our director nominees.

LOGOï 2020 Proxy Statement    3


Proxy Statement Summary

We Have Implemented Governance Best Practices

We continuously monitor developments and best practices in corporate governance and consider stockholder feedback when enhancing our governance structures. Below are highlights of our key governance practices:

Effective Board

Leadership and

Independent

Oversight

 Highly Independent Board – 10 of our 11 director nominees(page 25)

 Strong Refreshment Practices With 5 New Directors Since 2015 – Average Board tenure of approximately 5.5 years for our director nominees(pages 10 and 17)

 Annual Anonymous Board and Committee Evaluation Process(pages 17 and 24)

 All Directors Meet Our Board of Directors Guidelines for Director Qualifications and Evaluations(Appendix A)

 Robust Lead Independent Director Role(pages 18-19)

 Corporate Responsibility and Compliance Committee(page 27)

 Enterprise Risk Management Program and Annual Detailed Compensation Risk Analysis – overseen by Board and Compensation and Management Development Committee, respectively(pages 20  and 29-30)

Focus on

Stockholder Rights

 Proxy Access(pages 18 and 101)up to 20 eligible stockholders that own 3% of shares for 3 years who meet the requirements set forth in our Bylaws may have their director nominees constituting up to the greater of 20% of the total directors or two nominees included in our proxy materials

 Majority Voting Standard for Director Elections(pages 17 and 99)

 Stockholders* May Act By Written Consent(page 18)

 Stockholders* Have a Right to Call Special Meetings (15% threshold requirement)(page 18)

 No Supermajority Vote Provisions in Certificate of Incorporation or Bylaws(page 18)

 No Poison Pill(page 18)

History of

Transparency and

Accountability

 Significant Stock Ownership Requirements for Officers and Directors(pages 61-62 and 83)

 Regular Engagement With Stockholders to Seek Feedback (page 46)

 We Continue to Seek Mechanisms to Lower the Cost Burden on Society of Serious Diseases

 We Have Demonstrated our Commitment to Environmentally Responsible Operations, Improving Patient Access to Medicines, Science Education, and our Community (pages 31-33)

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF

THE 11 NAMED NOMINEES.

*

Who meet the requirements set forth in our Restated Certificate of Incorporation or our Amended and Restated Bylaws, as applicable.

4    LOGOï 2020 Proxy Statement


Proxy Statement Summary

Item 2: Advisory Vote to Approve Our Executive

Compensation (Page 34)

We Have Implemented Compensation Best PracticesLOGO

 

 

What we do

A substantial majority of Named Executive Officer compensation is performance based andat-risk

Recoupment in the case of misconduct causing serious financial or reputational damage

Clawback policy tied to financial restatement

Robust stock ownership and retention guidelines

Minimum vesting periods for equity compensation

Long-term performance-based equity awards (80% of total target equity)

Independent compensation consultant

What we don’t do

No hedging or pledging

LOGO

Nore-pricing or backdating

No taxgross-ups (except in connection with relocation)

No single-trigger for stock options and restricted stock units in the event of a change of control

No excessive perks

No employment agreements

No dividends paid on unvested equity

No defined benefit pension or supplemental executive retirement plan (SERP) benefits

NEO Compensation is Dependent on Our Performance

   A significant amount of each Named Executive Officer’s, or NEOs, compensation isat-risk and dependent on our performance and execution of our strategic priorities.

   We use median values as the reference point for each element of compensation at all levels, including our NEOs. We consider performance, job scope, and contribution in our final pay decisions.

2019 Total Target Direct Compensation Mix

LOGO

LOGOï 2020Board Tenure 2 4 4 2 ~ <3 Years 3-6 Years 7-9 Years >9 Years 6 Years Average Board Tenure Diverse Independent Director Perspectives 8 Experienced Current and Former Public Company CEOs/ CFO 6 Scientific Research and/or Healthcare Experience 4 Financial Industry Experience 3 Women 2 Racially /Ethnically Diverse Proxy Statement    5


Proxy Statement Summary

2019 Annual and Long-Term Awards Reflect Performance AgainstPre-Established Goals and Measures

2019 Annual Cash Incentive Program

 

 

2017-2019 Long-Term Incentive Performance Award Payout

 

Our annual cash incentive program is designed to focus our staff on delivering financial and operational objectives to drive annual performance, advance strategic priorities, and position us for long-term success.

 

 

80% of our annual long-term incentive, or LTI, equity award grants are performance-based, aligning compensation with long-term value creation for our stockholders. Three-year performance units comprise 50% of our LTI equity award grants, with the goal design and all measurement targets established at the beginning of the three-year performance period.

Goal

 

 

Weighting

 

  

 

% of Target 

Earned 

 

 LOGO

 

Financial Performance

 

 

Revenues

 

  

 

30%

 

 

 

 

177% 

 

 

Non-GAAP Net Income(1)

 

  

 

30%

 

 

 

 

168% 

 

 

Progress Innovative Pipeline

 

 

Advance Early Pipeline

 

  

 

10%

 

 

 

 

100% 

 

 

Execute Key Clinical Studies and Regulatory Filings

 

  

 

20%

 

 

 

 

80% 

 

 

Deliver Annual Priorities

 

 

Execute Critical Launches

and Long-Term

Commercial Objectives

 

  

 

5%

 

 

 

 

77% 

 

 

Achieve Productivity Objectives

 

  

 

5%

 

 

 

 

107% 

 

 

Final Score

 

  

 

Achieved 138.9% 

 

(1)

Non-GAAP net income for purposes of the 2019 Company performance goals of our annual cash incentive award program is reported and reconciled inAppendix B.

(2)

The operating measures of the 2017-2019 performance goals were based onnon-GAAP financial results for 2017, 2018, and 2019 as reported and reconciled inAppendix B, except that operating measures were further adjusted for the impacts of Hurricane Maria as prescribed by the terms of the 2017-2019 performance goals document as follows: operating expense was reduced by $147 million ($0.16 in EPS) for 2017, increased by $21 million ($0.03 in EPS) for 2018, and increased by $49 million ($0.07 in EPS) for 2019.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPROVAL OF THE

  ADVISORY RESOLUTION INDICATING THE APPROVAL OF THE COMPENSATION OF THE  

COMPANY’S NAMED EXECUTIVE OFFICERS.

Access FOR DIRECTOR NOMINATIONS ~92% INDEPENDENT DIRECTORS Lead INDEPENDENT DIRECTOR 7 NEW DIRECTORS SINCE 2015 ~ 6 LOGOï 2020 Proxy Statement


Proxy Statement Summary

Item 3: Ratification of Selection of Independent Registered

Public Accountants (Page 90)

The Audit Committee of the Board has selected Ernst & Young LLP, or EY, as our independent registered public accountants for the fiscal year ending December 31, 2020.

EY has served as our independent registered public accounting firm since the Company’s inception in 1980.

Each year, the Audit Committee evaluates the qualifications and performance of the Company’s independent registered public accountants and determines whether tore-engage the current independent registered public accountants.

Based on this evaluation, the Audit Committee believes that the continued retention of EY is in the best interests of the Company and its stockholders.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” RATIFICATION OF OUR

INDEPENDENT REGISTERED PUBLIC ACCOUNTANTS.

Item 4: Stockholder Proposal (Page 93)

Stockholder proposal to require an independent Board Chair, if properly presented.

Independent Oversight. Our Company has numerous mechanisms that ensure independent oversight of the Company’s affairs and that facilitate communication with, and independent evaluation of, senior management, including:

-

An active lead independent director elected annually by and from the independent directors with a robust set of duties and authority outlined below;

-

Strong Board and committee involvement to provide sound and robust oversight of management;

-

Regular communication between the lead independent director, the independent directors, and Robert A. Bradway, keeping Mr. Bradway apprised of any concerns, issues, or determinations made during the independent sessions, and consulting with Mr. Bradway on other matters pertinent to the Company and the Board;

-

Diverse, experienced, and skilled directors, with ten of our eleven director nominees independent as defined by The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission;

-

All members of the Board’s key committees are independent; and

-

A meeting of the independent directors is scheduled at every regular Board meeting and the independent directors meet in executive session without Mr. Bradway to review Company performance, management effectiveness, proposed programs and transactions, and the Board meeting agenda items.

Leadership Structure.Our governance documents give the Board discretion in determining whether to separate or combine the roles of the Chairman and Chief Executive Officer. This flexibility permits the Board to choose a leadership structure that can be tailored to the strengths of the Company’s officers and directors and to best address our evolving and highly complex business.

LOGOï 2020 Proxy Statement    7


Proxy Statement Summary

Annual Evaluation of Leadership Structure.The Board conducts annual evaluations of the Company’s leadership structure and determined that the Company and its stockholders are best served at this time by having Mr. Bradway serve as both Chairman and Chief Executive Officer, coupled by a separate active lead independent director, currently served by Robert A. Eckert.

Our Lead Independent Director Responsibilities

The lead independent director’s responsibilities outlined in the Amgen Board of Directors Corporate Governance Principles include:

- Approving meeting agendas for the Board;

- Assuring that there is sufficient time for discussion of all meeting agenda items;

- Previewing the information to be provided to the Board;

- Having the authority to call meetings of the independent directors;

- Organizing and leading the Board’s evaluation of the CEO;

- Serving as a liaison between the Chairman and the independent directors;

- Leading the Board’s annual self-assessment;

- Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

- Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

In addition to the responsibilities outlined above, the lead independent director:

- Meets with the Chairman prior to each regular meeting of the Board and its committees to discuss, provide input on, and approve the agendas;

- With the Chairman, determines presenters for attendance at Board meetings;

- Hasone-on-one discussions with each independent director, including as part of the Board’s annual evaluation process;

- Attends all committee meetings, including those committees for which he is not a member (at his discretion) and is provided with access to all committee materials;

- Has the authority to engage independent consultants;

- Is regularly apprised of inquiries from stockholders;

- Interviews Board candidates; and

- Has an increased role in crisis management, as appropriate.

Please see “Leadership Structure” in the Corporate Governance section for a full discussion of our current leadership structure and lead independent director responsibilities.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “AGAINST” THE

STOCKHOLDER PROPOSAL.

years AVERAGE TENURE 8 LOGOï 2020 Proxy StatementCURRENT/ FORMER PUBLIC COMPANY CEO/CFOs


Item 1 — Election of Directors

Item 1

Election of Directors

Under our governance documents, the Board of Directors, or Board, has the power to set the number of directors from time to time by resolution. We currently have 12 authorized directors serving on our Board. Based upon the recommendation of our Governance and Nominating Committee, the Board has nominated each of the director nominees set forth below to stand forre-election as a director, in each case for aone-year term expiring at our 2021 annual meeting of stockholders and until his or her successor is elected and qualified, or until his or her earlier retirement, resignation, disqualification, removal, or death. Rebecca M. Henderson is not standing forre-election at the 2020 Annual Meeting of Stockholders, or Annual Meeting, after ten years of valuable service to the Company.

The Board has fixed the authorized number of directors at 11 to be effective as of the close of the Annual Meeting and the election by stockholders of the nominees standing for election. Each nominee has agreed to serve if elected and the Board has no reason to believe that any nominee will be unable to serve. However, if any nominee should

become unavailable for election prior to the Annual Meeting, the proxies will be voted in favor of the election of a substitute nominee or nominees proposed by the Board or, alternatively, the number of directors may be reduced accordingly by the Board. Vacancies on the Board (including any vacancy created by an increase in the size of the Board) may be filled only by a majority of the directors remaining in office, even though less than a quorum of the Board. A director elected by the Board to fill a vacancy (including a vacancy created by an increase in the size of the Board) will serve until the next annual meeting of stockholders and until such director’s successor is elected and qualified, or until such director’s earlier retirement, resignation, disqualification, removal, or death.

The independent members of the Board have elected Robert A. Eckert to continue to serve as our lead independent director, subject to hisre-election to the Board by our stockholders at the Annual Meeting. As lead independent director, Mr. Eckert will continue to have the specific and significant duties as discussed under “Corporate Governance.”

Nominees to the Board

 

 

  

  Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive    

Compensation

and

Management

Development

 

 

 

 

   

Equity

Award

 

 

   

Corporate  

Responsibility  

and  

Compliance  


 

 

  Wanda M. Austin

 

   

 

 

 

 

   

 

65

 

 

 

   

 

2017

 

 

 

   

 

M

 

 

 

       

 

M

 

 

 

    
 

 

  Robert A. Bradway

 

     

 

57

 

 

 

   

 

2011

 

 

 

       

 

C

 

 

 

     

 

M

 

 

 

  
 

 

  Brian J. Druker

 

   

 

 

 

 

   

 

64

 

 

 

   

 

2018

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Robert A. Eckert

 

   

 

 

 

 

   

 

65

 

 

 

   

 

2012

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

   

 

C

 

 

 

    
 

 

  Greg C. Garland

 

   

 

 

 

 

   

 

62

 

 

 

   

 

2013

 

 

 

     

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

    
 

 

  Fred Hassan

 

   

 

 

 

 

   

 

74

 

 

 

   

 

2015

 

 

 

   

 

M

 

 

 

       

 

M

 

 

 

    
 

 

  Charles M. Holley, Jr.

 

   

 

 

 

 

   

 

63

 

 

 

   

 

2017

 

 

 

   

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

      
 

 

  Tyler Jacks

 

   

 

 

 

 

   

 

59

 

 

 

   

 

2012

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Ellen J. Kullman

 

   

 

 

 

 

   

 

64

 

 

 

   

 

2016

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

        
 

 

  Ronald D. Sugar

 

   

 

 

 

 

   

 

71

 

 

 

   

 

2010

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

       

 

C

 

 

 

  

 

  R. Sanders Williams

 

   

 

 

 

 

   

 

71

 

 

 

   

 

2014

 

 

 

        

 

M

 

 

 

                  

 

M

 

 

 

  

  Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive    

Compensation

and

Management

Development

 

 

 

 

   

Equity

Award

 

 

   

Corporate  

Responsibility  

and  

Compliance  


 

 

  Wanda M. Austin

 

   

 

 

 

 

   

 

67

 

 

 

   

 

2017

 

 

 

   

 

M

 

 

 

       

 

M

 

 

 

    
 

 

  Robert A. Bradway

 

     

 

59

 

 

 

   

 

2011

 

 

 

       

 

C

 

 

 

     

 

M

 

 

 

  
 

 

  Brian J. Druker

 

   

 

 

 

 

   

 

66

 

 

 

   

 

2018

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Robert A. Eckert*

 

   

 

 

 

 

   

 

67

 

 

 

   

 

2012

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

   

 

C

 

 

 

    
 

 

  Greg C. Garland

 

   

 

 

 

 

   

 

64

 

 

 

   

 

2013

 

 

 

     

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

    
 

 

  Charles M. Holley, Jr.

 

   

 

 

 

 

   

 

65

 

 

 

   

 

2017

 

 

 

   

 

C

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

      
 

 

  S. Omar Ishrak

 

   

 

 

 

 

   

 

66

 

 

 

   

 

2021

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Tyler Jacks

 

   

 

 

 

 

   

 

61

 

 

 

   

 

2012

 

 

 

         

 

M

 

 

 

     

 

M

 

 

 

 

 

  Ellen J. Kullman

 

   

 

 

 

 

   

 

66

 

 

 

   

 

2016

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

        
 

 

  Amy E. Miles

 

   

 

 

 

 

   

 

55

 

 

 

   

 

2020

 

 

 

   

 

M

 

 

 

   

 

M

 

 

 

        
 

 

  Ronald D. Sugar

 

   

 

 

 

 

   

 

73

 

 

 

   

 

2010

 

 

 

     

 

M

 

 

 

   

 

M

 

 

 

       

 

C

 

 

 

  

 

  R. Sanders Williams

 

   

 

 

 

 

   

 

73

 

 

 

   

 

2014

 

 

 

        

 

M

 

 

 

                  

 

M

 

 

 

 

“*”

indicates Lead Independent Director.

“C”

indicates Chair of the committee.

“M”

indicates member of the committee.

 

2    LOGO  ï 20202022 Proxy Statement


Proxy Statement Summary

    9We Have Implemented Governance Best Practices

We continuously monitor developments and best practices in corporate governance and consider stockholder feedback when enhancing our governance structures. Below are highlights of our key governance practices:


Effective Board    

Leadership and    

Independent    

Oversight    

 Highly Independent Board – 11 of our 12 director nominees (page 28)

 Regular Executive Sessions of Independent Directors and Access to Management (pages 17, 19 and 27)

 Continuous Refreshment Practices (pages 17 and 24-26)

  7 New Directors Since 2015

  3 Women and 2 Racially/Ethnically Diverse Directors

  Average Board Tenure of Approximately 6 Years for Our Directors

 Annual Anonymous Board and Committee Evaluation Process (pages 17 and 27)

 All Directors Meet Our Board of Directors Guidelines for Director Qualifications and Evaluations (Appendix A)

 Robust Lead Independent Director Role (pages 17-20)

 Limitation on Number of Other Boards (page 17)

 Corporate Responsibility and Compliance Committee (page 30)

 Enterprise Risk Management Program and Annual Compensation Risk Analysis – overseen by Board and Compensation and Management Development Committee, respectively (pages 20-21 and 37-38)


Focus on    

Stockholder Rights    

 Single Class of Shares – One share equals one vote (page 18)

 Proxy Access – Up to 20 eligible stockholders who own 3% of shares for 3 years who meet the requirements set forth in our Bylaws may have their director nominees constituting up to the greater of 20% of the total directors or two nominees included in our proxy materials (pages 18 and 102)

 Majority Voting Standard for Director Elections (pages 17 and 100-101)

 Stockholders(1) May Act By Written Consent (page 18)

 Stockholders(1) Have a Right to Call Special Meetings (15% threshold requirement) (page 18)

 No Supermajority Vote Provisions in Certificate of Incorporation or Bylaws (page 18)

 No Poison Pill (page 18)


History of    

Transparency and    

Accountability    

 Regular Engagement With Stockholders to Seek Feedback (pages 17, 31 and 51)

 Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance (ESG), Has Delivered Environmentally Responsible Operations, Improved Patient Access to Medicines, Provided High Quality, Free Science Education Resources, and Benefited the Communities Where We Live and Work (pages 31-35)

  We expanded our ESG reporting in 2021. Our latest Environmental, Social, and Governance Report maps our reporting to the Sustainability Accounting Standards Board (SASB) standards for our industry and, to enhance transparency around the composition of our workforce, we disclose our annual Consolidated EEO-1 Report.(2)

 Significant Stock Ownership Requirements for Officers and Directors (pages 37, 44, 68-69 and 87)

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF

THE 12 NAMED NOMINEES.

(1)

Who meet the requirements set forth in our Restated Certificate of Incorporation or our Amended and Restated Bylaws, as applicable.

(2)

Beginning with our Consolidated EEO-1 Report filed in 2021.

LOGO ï 2022 Proxy Statement3


Proxy Statement Summary

Item 2: Advisory Vote to Approve Our Executive

Compensation (Page 40)

Our executive compensation program is designed to reward and drive long-term performance in support of our strategy.

2021 Business Highlights

Our strategy includes a series of integrated activities designed to strengthen our long-term competitive position in the industry. Despite the onset of the COVID-19 pandemic in 2020, we have remained focused on our strategic priorities and our values while closely managing the effects of the pandemic on our global operations.

We delivered strong performance in 2021. We launched new products, advanced our innovative pipeline, completed several strategic transactions to augment our pipeline and research capabilities, and continued to provide uninterrupted supply of our medicines globally.

2021 Product Launches

LOGO

LUMAKRAS®for the treatment of

advanced non-small cell lung cancer

LOGO

TEZSPIRE(1) for the treatment of

severe asthma

LOGO

Expanded indication for Otezla® for the treatment of plaque psoriasis across all severities (mild, moderate, and severe)

Key 2021 Strategic Business Transactions That Complement Our Internal Innovation

LOGO

Acquired Five Prime Therapeutics, Inc., and bemarituzumab, a first-in-class antibody in oncology

LOGO

Acquired Teneobio, Inc. and its proprietary bispecific and multispecific antibody technologies and portfolio of early-stage oncology assets.

Entered into a collaboration with Kyowa Kirin Co. Ltd. to develop and commercialize AMG 451, a Phase 3-ready first-in-class asset in inflammation.

Executed key clinical studies and advanced innovative first-in-class pipeline:

Advanced bemarituzumab into Phase 3 for the treatment of patients with human epidermal growth factor receptor 2 negative FGFR2b-positive gastric and gastroesophageal junction cancer;

Expanded KYPROLIS® U.S. prescribing information to include its use in combination with DARZALEX FASPRO®(2) and dexamethasone for patients with multiple myeloma at first or subsequent relapse; and

Progressed our early innovative pipeline forming 7 product teams(3), initiating 4 first-in-human studies, and advancing 4 programs through our early-to-late stage portal.

We accomplished these objectives while maintaining a strategic and disciplined approach to capital allocation, and advancing our environmental sustainability, social responsibility, and corporate

governance. Our strong cash flows and balance sheet allowed for significant investment in 2021 for long-term growth, while simultaneously providing substantial returns to stockholders.

In 2021, while investing $4.8 billion in research and development, $2.5 billion in strategic business acquisitions, and

$880 million in capital projects, we also returned $9 billion of capital to our stockholders ($4 billion of dividends and

$5 billion in share repurchases)

(1)

Being developed in collaboration with AstraZeneca plc.

(2)

DARZALEX FASPRO is a registered trademark of Janssen Biotech, Inc.

(3)

Formed when a molecule has been judged to have the potential to be safe and effective in humans.

4    LOGO ï  2022 Proxy Statement


Proxy Statement Summary

NEO Compensation Is Dependent on Our Performance

A significant amount of each Named Executive Officer’s, or NEOs, compensation is at-risk and dependent on our performance and execution of our strategic priorities.

2021 Total Target Direct Compensation Mix

LOGO

2021 Annual and Long-Term Awards Reflect Performance Against Pre-Established Goals and Measures

2021 Annual Cash Incentive Plan

 

  

2019-2021 Long-Term Incentive Performance Award Payout

 

Our annual cash incentive plan is designed to focus our staff members on delivering financial and operational objectives to drive annual performance, advance strategic priorities, and position us for long-term success.

 

  

80% of our annual LTI equity award grants are performance-based, aligning compensation with long-term value creation for our stockholders. Performance units comprise 50% of our annual LTI equity award grants, with the goal design and all measurement targets established at the beginning of the three-year performance period.

 

 

Goal

  Weighting   

% of
Target

Earned

 
 

 

 Weighted   Score   Achieved(1)   

 

 

 

LOGO

Financial Performance

 

 62.1%  

Revenues

  30%   87.6%   

 

Non-GAAP Net Income(2)

  30%   119.5%   

 

Progress Innovative Pipeline

 

 53.6%  

Advance Early Pipeline

  10%   200.0%   

 

Execute Key Clinical Studies and Regulatory Filings

  20%   167.9%   

 

Deliver Annual Priorities

 

 21.0%  

Environmental, Social, and Governance

  5%   195.8%   

 

Digital Transformation

  5%   225.0%   

 

Final Score

  136.8%   

(1)

Percentages do not total to final score due to rounding.

(2)

Non-Generally Accepted Accounting Principles (non-GAAP) net income for purposes of the 2021 Company performance goals of our annual cash incentive plan is reported and reconciled in Appendix B.

(3)

The non-GAAP operating measures (EPS growth and return on invested capital, or ROIC) with respect to the 2019-2021 performance period are as reported and reconciled in Appendix B, except that operating measures for 2021 performance were further adjusted to include the impacts of gains on equity investments as prescribed by the 2019-2021 performance goals document. For this purpose, non-GAAP net income was increased by $338 million, or $0.59 per share and the tax rate used to calculate ROIC was adjusted accordingly to approximately 13.1%, resulting in a 0.1% reduction in ROIC.

LOGO ï 2022 Proxy Statement5


Proxy Statement Summary

We Have Implemented Compensation Best Practices

What we do

Long-term performance-based equity awards (80% of total target equity, of which 50% are three-year performance unit awards and 30% are stock options)

A substantial majority of NEO compensation is performance-based and at-risk

Recoupment provisions for misconduct that causes serious financial or reputational damage include forfeiture and cancellation of unvested or unexercised(1) equity awards and annual cash incentive awards being deemed not earned in full or part

Clawback policy tied to financial restatement and misconduct that permits recapture of past cash or long-term incentive equity award payouts

Robust stock ownership (6x for Chief Executive Officer) and retention guidelines

Minimum vesting periods of one year, with most equity grants vesting over four years (with no vesting in the first year and vesting in three approximately equal installments thereafter)

We use market median values as the reference point for each element of compensation at all job levels, including our NEOs

Independent compensation consultant

Amgen Values overlay our performance goals

What we don’t do

×

No alterations to our established goals to respond to changing business conditions (for example, we have not made any changes to established goals in response to the occurrence or challenges of the pandemic)

×

No hedging or pledging

×

No re-pricing or backdating

×

No tax gross-ups (except in connection with relocation)

×

No single-trigger for stock options and restricted stock units in the event of a change of control

×

No excessive perks

×

No employment agreements

×

No dividends paid on unvested equity

×

No defined benefit pension or supplemental executive retirement plan (SERP) benefits

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPROVAL OF THE

ADVISORY RESOLUTION TO APPROVE THE COMPENSATION OF THE

COMPANY’S NAMED EXECUTIVE OFFICERS.

(1)

Forfeiture and cancellation applies to any unvested or unexercised portion of any stock options granted after December 31, 2020.

6    LOGO ï 2022 Proxy Statement


Proxy Statement Summary

Item 3: Ratification of Selection of Independent Registered Public Accountants (Page 94)

Each year, the Audit Committee evaluates the qualifications and performance of the Company’s independent registered public accountants and determines whether to re-engage the current independent registered public accountants.

Based on this evaluation, the Audit Committee believes that the continued retention of Ernst & Young LLP, or EY, is in the best interests of the Company and its stockholders.

The Audit Committee of the Board has selected EY as our independent registered public accountants for the fiscal year ending December 31, 2022.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” RATIFICATION OF OUR

INDEPENDENT REGISTERED PUBLIC ACCOUNTANTS.

LOGO ï 2022 Proxy Statement7


    

 

 

 

 

Item 1 — Election of Directors

 

 

 

 

 

Item 1

Election of Directors

Under our governance documents, the Board of Directors, or Board, has the power to set the number of directors from time to time by resolution. The Board has fixed the authorized number of directors at 12 and we currently have 12 directors serving on our Board. Our Board is composed of directors with a wide range of relevant experiences and backgrounds and considers a number of attributes when seeking new candidates for the Board as discussed more fully below and in the section “Corporate Governance—Process for Selecting Directors, Director Qualifications, and Board Diversity.” Based upon the recommendation of our Governance and Nominating Committee, or Governance Committee, the Board has nominated each of the director nominees set forth below to stand for election as a director, in each case for a one-year term expiring at our 2023 annual meeting of stockholders and until his or her successor is elected and qualified, or until his or her earlier retirement, resignation, disqualification, removal, or death.

Each nominee has agreed to serve if elected and the Board has no reason to believe that any nominee will be unable to serve. However, if

any nominee should become unavailable for election prior to the 2022 Annual Meeting of Stockholders, or Annual Meeting, proxies will be voted in favor of the election of a substitute nominee or nominees proposed by the Board or, alternatively, the number of directors may be reduced accordingly by the Board. Vacancies on the Board (including any vacancy created by an increase in the size of the Board) may be filled only by a majority of the directors remaining in office, even if less than a quorum of the Board. A director elected by the Board to fill a vacancy (including a vacancy created by an increase in the size of the Board) will serve until the next annual meeting of stockholders and until such director’s successor is elected and qualified, or until such director’s earlier retirement, resignation, disqualification, removal, or death.

The independent members of the Board have elected Robert A. Eckert to continue to serve as our lead independent director, subject to his re-election to the Board by our stockholders at the Annual Meeting. As lead independent director, Mr. Eckert will continue to have the specific and significant duties as discussed under “Corporate Governance.”

Nominees to the Board

  

Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive   

 

 

 

Compensation

and

Management

Development

 

 

 

 

 

   

Equity

Award

 

 

   

Corporate  

Responsibility  

and  

Compliance  

 

 

 

 

 

Wanda M. Austin

  

 

 

  

 

67

 

  

 

2017

 

  

 

M

 

      

 

M

 

    
 

Robert A. Bradway

    

 

59

 

  

 

2011

 

      

 

C

 

    

 

M

 

  
 

Brian J. Druker

  

 

 

  

 

66

 

  

 

2018

 

        

 

M

 

    

 

M

 

 

Robert A. Eckert*

  

 

 

  

 

67

 

  

 

2012

 

    

 

M

 

  

 

M

 

  

 

C

 

    
 

Greg C. Garland

  

 

 

  

 

64

 

  

 

2013

 

    

 

C

 

  

 

M

 

  

 

M

 

    
 

Charles M. Holley, Jr.

  

 

 

  

 

65

 

  

 

2017

 

  

 

C

 

  

 

M

 

  

 

M

 

      
 

S. Omar Ishrak

  

 

 

  

 

66

 

  

 

2021

 

        

 

M

 

    

 

M

 

 

Tyler Jacks

  

 

 

  

 

61

 

  

 

2012

 

        

 

M

 

    

 

M

 

 

Ellen J. Kullman

  

 

 

  

 

66

 

  

 

2016

 

  

 

M

 

  

 

M

 

        
 

Amy E. Miles

  

 

 

  

 

55

 

  

 

2020

 

  

 

M

 

  

 

M

 

        
 

Ronald D. Sugar

  

 

 

  

 

73

 

  

 

2010

 

    

 

M

 

  

 

M

 

      

 

C

 

  

R. Sanders Williams

  

 

 

  

 

73

 

  

 

2014

 

       

 

M

 

                 

 

M

 

“*”

indicates Lead Independent Director.

“C”

indicates Chair of the committee.

“M”

indicates member of the committee.

8    LOGO ï 2022 Proxy Statement


Item 1 — Election of Directors

Summary of Director Nominee Core Experiences and Skills

 

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, have gained significant and wide-ranging management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees), an understanding of corporate governance practices and trends, and bring unique perspectives to the Board. A number of our directors have extensive scientific and healthcare expertise relevant to our industry, including pioneering scientific research in the areas of oncology and cardiology and experience leading important academic institutions. The Board and the Governance Committee believe the skills, qualities, attributes, experience and diversity of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director nominee to be represented on our Board.nominee. The details of each director’snominee’s competencies are included in each director’s profile.nominee’s biography.

 

 

LOGOLOGO

Experience / Experience/Skills Austin Bradway Druker Eckert Garland Hassan Henderson Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

 

LOGO

*

For our director nominees.

10    LOGO  ï 20202022 Proxy Statement9


    

 

 

 

 

Item 1 — Election of Directors

 

 

 

 

 

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE NAMED NOMINEES. PROXIES WILL BE VOTED “FOR” THE ELECTION OF THE NOMINEES UNLESS OTHERWISE SPECIFIED.

Set forth below is biographical information for each nominee and a summary of the specific qualifications, attributes, skills, and experiences which led our Board to conclude that each nominee should serve on the Board at this time. All of our directors meet the qualifications and skills of our Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations included in this proxy statement asAppendix A. There are no family relationships among any of our directors or among any of our directors and our executive officers.

 

 

Wanda M. Austin

 

LOGO

 

 

Director since: 2017

 

Age:6567

 

Committees:

  Audit

  Compensation and Management Development

 

Other Public Company Boards:

  Chevron Corporation

  Virgin Galactic Holdings, Inc.

 

   

 

Wanda M. Austin is the retired President and Chief Executive Officer of The Aerospace Corporation, a leading architect of the United States’ national security space programs, where she served from 2008 until her retirement in 2016. From 2004 to 2007, Dr. Austin was Senior Vice President, National Systems Group of The Aerospace Corporation. Dr. Austin joined The Aerospace Corporation in 1979 and served in various positions from 1979 until 2004.

 

Dr. Austin served aswas the Interim President of the University of Southern California, or USC, from August 2018 until June 2019. Sheto 2019 and has served as an Adjunct Research Professor at the University of Southern California’sUSC’s Viterbi School of Engineering since 2007. She is theco-founder of MakingSpace, Inc., where she serves as a motivational speaker on STEM education. Dr. Austin has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2016, serving on its Board Nominating and GovernanceManagement Compensation Committee and chairing its Public PolicyBoard Nominating and Governance Committee. Dr. Austin has been a director of Virgin Galactic Holdings, Inc., a commercial space flight company, since October 2019 and is a member of its Audit Committee and Safety Committee, and chairChair of its Compensation Committee. Dr. Austin is a life trustee of the University of Southern CaliforniaUSC, having served as a voting trustee from 2010 to March 2021, and previously served on the boards of directors of the National Geographic Society and the Space Foundation. Dr. Austin received an undergraduate degree from Franklin & Marshall College, a master’s degree from the University of Pittsburgh, and a doctorate from the University of Southern California.USC. She is a member of the National Academy of Engineering.

 

Qualifications

 

The Board concluded that Dr. Austin should serve on the Board based on her leadership and management experience as a chief executive officer, her extensive background in science, technology, and government affairs in a highly regulated industry, and her public board experience.

 

 

Robert A. Bradway

 

LOGO

 

 

Director since:2011

 

Age:5759

 

Committees:

  Equity Award

  Executive (Chair)

 

Other Public Company Boards:

  The Boeing Company

 

   

 

Robert A. Bradway has served as our director since 2011 and Chairman of the Board since 2013. Mr. Bradway has been our President since 2010 and Chief Executive Officer since 2012. From 2010 to 2012, Mr. Bradway served as our Chief Operating Officer. Mr. Bradway joined Amgen in 2006 as Vice President, Operations Strategy and served as Executive Vice President and Chief Financial Officer from 2007 to 2010. Prior to joining Amgen, he was a Managing Director at Morgan Stanley in London where, beginning in 2001, he had responsibility for the firm’s banking department and corporate finance activities in Europe.

 

Mr. Bradway has been a director of The Boeing Company, an aerospace company and manufacturer of commercial airplanes, defense, space and securities systems, since 2016, serving on its Auditas the Chair of the Finance Committee and Finance Committees.a member of the Governance and Public Policy Committee. From 2011 to 2017, Mr. Bradway was a director of Norfolk Southern Corporation, a transportation company. He has served on the board of trustees of the University of Southern California since 2014 and on the advisory board of the Leonard D. Schaeffer Center for Health Policy and Economics at that university since 2012.2014. Mr. Bradway holds a bachelor’s degree in biology from Amherst College and a master’s degree in business administration from Harvard Business School.

 

Qualifications

 

The Board concluded that Mr. Bradway should serve on the Board based on his thorough knowledge of all aspects of our business, combined with his leadership and management skills having previously served as our President and Chief Operating Officer and as our Chief Financial Officer.

 

10    LOGO  ï 20202022 Proxy Statement    11


    

 

 

 

 

Item 1 — Election of Directors

 

 

 

 

 

 

Brian J. Druker

 

LOGO

 

 

Director since:2018

 

Age:6466

 

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Vincerx Pharma, Inc.

 

   

 

Brian J. Druker joined Oregon Health & Science University, or OHSU, in 1993 and is currently a physician-scientist and professor of medicine. Dr. Druker has served as the director of the OHSU Knight Cancer Institute since 2007, associate dean for oncology of the OHSU School of Medicine since 2010, and theJELD-WEN chair of leukemia research at OHSU since 2001. He was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, from 2002 to 2019.

 

Dr. Druker has been a director of Vincerx Pharma, Inc., a biopharmaceutical company, since December 2020, and serves on its Nominating and Corporate Governance Committee. Dr. Druker has served on the scientific advisory board of Aptose Biosciences Inc., a biotechnology company, since 2013. Dr. Druker was on the scientific advisory board ofhas been a consultant to Grail, Inc., a biotechnology company, since 2021, and served on its scientific advisory board, from 2016 to 2019. In 2011, he founded Blueprint Medicines Corporation, a biopharmaceutical company, and remains as a scientific advisor to this company. In 2006, he founded MolecularMD, a privately-held molecular diagnostics company that was acquired by ICON plc in 2019.

 

Dr. Druker has received numerous awards, including the Lasker-DeBakey Clinical Research Award in 2009, the Japan Prize in Healthcare and Medical Technology in 2012, the Albany Medical Center Prize in 2013, and the Sjöberg Prize in 2019, for influential work in the development of STI571 (Gleevec®) for the treatment of chronic myeloid leukemia. He was elected to the National Academy of Sciences in 2012 as well as the National Academy of Medicine in 2007. Dr. Druker received both an undergraduate degree and his medical doctorate from the University of California, San Diego.

Qualifications

The Board concluded that Dr. Druker should serve on the Board based on his extensive scientific research and expertise leading an important academic institution, conducting highly significant research in the area of oncology, and directly managing the care of cancer patients.

 

 

Robert A. Eckert

 

Lead Independent Director

 

LOGO

 

 

Director since:2012

 

Age:6567

 

Committees:

  Compensation and Management Development (Chair)

  Executive

  Governance and Nominating

 

Other Public Company Boards:

  Levi Strauss & Co.

  McDonald’s Corporation

  Uber Technologies, Inc.

 

   

 

Robert A. Eckert is our lead independent director. Mr. Eckert has been an Operating Partner at FFL Partners, LLC (formerly known as Friedman Fleischer & Lowe, LLP), a private equity firm, since 2014. Mr. Eckert was the Chief Executive Officer of Mattel, Inc., a toy design, manufacture and marketing company, having held this position from 2000 through 2011, and its Chairman of the Board from 2000 through 2012. He was President and Chief Executive Officer of Kraft Foods Inc., a consumer packaged food and beverage company, from 1997 to 2000, Group Vice President from 1995 to 1997, President of the Oscar Mayer Foods Division from 1993 to 1995 and held various other senior executive and other positions from 1977 to 1992.

 

Mr. Eckert has been a director of McDonald’s Corporation, a company whichthat franchises and operates McDonald’s restaurants in the global restaurant industry, since 2003, serving as the Chair of the Public Policy and Strategy Committee and a member of the Executive and Governance Committees. Mr. Eckert also has served as a director of Levi Strauss & Co., a jeans and casual wear manufacturer, since 2010, serving as Chair of the CompensationNominating, Governance and Corporate Citizenship Committee and a member of the Nominating, GovernanceCompensation Committee and, Corporate Citizenship Committee. Levi Strauss & Co. was a privately-held company untilsince March 2019 when it became publicly traded.2021, as non-executive Chair of the board. In March 2020, Mr. Eckert was appointed a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, serving on itsas Chair of the Compensation Committee and a member of the Nominating and Governance Committees.Committee. Mr. Eckert was a director of Smart & Final Stores, Inc., a warehouse store, from 2013 until 2014 prior to it becoming a publicly-traded company. He was appointed director of Eyemart Express Holdings LLC, a privately-held eyewear retailer and portfolio company of Friedman Fleischer & Lowe,FFL Partners, LLC, in 2015. Mr. Eckert is on the Global Advisory Board of the Kellogg School of Management at Northwestern University and serves on the Eller College National Board of Advisors at the University of Arizona. Mr. Eckert received an undergraduate degree from the University of Arizona and a master’s degree in business administration from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Mr. Eckert should serve on our Board because of Mr. Eckert’s long-tenured experience as a chief executive officer and director of large public companies, his broad international experience in marketing and business development, and his valuable leadership experience.

Qualifications

The Board concluded that Mr. Eckert should serve on our Board because of Mr. Eckert’s long-tenured experience as a chief executive officer and director of large public companies, his broad international experience in marketing and business development, and his valuable leadership experience.

12    LOGO  ï 20202022 Proxy Statement11


    

 

 

 

 

Item 1 — Election of Directors

 

 

 

 

 

 

Greg C. Garland

 

LOGO

LOGO

Director since:2013

 

Age:6264

 

Committees:

  Compensation and Management Development

  Executive

  Governance and Nominating (Chair)

 

Other Public Company Boards:

  Phillips 66(1)

 

   

 

Greg C. Garland is the Chairman and Chief Executive Officer of Phillips 66, a diversified energy manufacturing and logistics company created through the repositioning of ConocoPhillips, having held this position since 2012. Mr. Garland chairs the Executive Committee of Phillips 66.1(1) Prior to Phillips 66, Mr. Garland served as Senior Vice President, Exploration and Production, Americas of ConocoPhillips from 2010 to 2012. He was President and Chief Executive Officer of Chevron Phillips Chemical Company (now a joint venture between Phillips 66 and Chevron) from 2008 to 2010 and Senior Vice President, Planning and Specialty Chemicals from 2000 to 2008. Mr. Garland served in various positions at Phillips Petroleum Company from 1980 to 2000. Mr. Garland is a member of the Engineering Advisory Council for Texas A&M University. Mr. Garland received an undergraduate degree from Texas A&M University.

 

Qualifications

 

The Board concluded that Mr. Garland should serve on our Board because of Mr. Garland’s experience as a chief executive officer and his over 30 years of international experience in a highly regulated industry.

 

 

(1) 

Mr. Garland also servesserved as Chairman and Chief Executive Officer of Phillips 66 Partners LP, a master limited partnership and wholly-owned subsidiary of Phillips 66 without any employees.employees, until its full acquisition in March 2022 by Phillips 66.

Fred Hassan

LOGO

Director since:2015

Age:74

Committees:

  Audit

  Compensation and Management Development

Other Public Company Boards:

  Intrexon Corporation

Audit Committee financial expert

Fred Hassan is Director at Warburg Pincus LLC, a global private equity investment institution, since 2018. Mr. Hassan was Special Limited Partner at Warburg Pincus LLC from 2017 to 2018 and Partner and Managing Director from 2011 to 2017 and, prior to that, served as Senior Advisor from 2009 to 2010. Mr. Hassan was Chairman of the Board and Chief Executive Officer of Schering-Plough Corporation from 2003 to 2009. Prior to this, Mr. Hassan was Chairman, President and Chief Executive Officer of Pharmacia Corporation, from 2001 to 2003. Before assuming these roles, he had served as President and Chief Executive Officer of Pharmacia Corporation from its creation in 2000 as a result of the merger of Pharmacia & Upjohn, Inc. with Monsanto Company. He was President and Chief Executive Officer of Pharmacia & Upjohn, Inc. beginning in 1997. Mr. Hassan previously held senior positions with Wyeth (formerly known as American Home Products), including that of Executive Vice President with responsibility for its pharmaceutical and medical products businesses, and served as a member of the board from 1995 to 1997. Prior to that, Mr. Hassan held various roles at Sandoz Pharmaceuticals and headed its U.S. pharmaceuticals businesses.

Mr. Hassan has been a director of Intrexon Corporation, a synthetic biology company, since 2016, serving on its Compensation Committee. Mr. Hassan was a director of Time Warner Inc., a media company, from 2009 until its acquisition by AT&T Inc., a provider of communications and digital entertainment services, in 2018.Mr. Hassan was a director of Avon Products, Inc., a manufacturer and marketer of beauty and related products, from 1999 until 2013 and served on its Compensation and Management Development, Nominating and Corporate Governance and Audit Committees, as lead independent director from 2009 to 2012, and Chairman of the Board between January and April 2013. Mr. Hassan was Chairman of the Board of Bausch & Lomb, from 2010 until its acquisition by Valeant Pharmaceuticals International, Inc., a pharmaceutical company, in 2013. Mr. Hassan served on the board of directors and the Compensation and Audit Committees of Valeant Pharmaceuticals International, Inc. from 2013 to 2014. Mr. Hassan received an undergraduate degree from Imperial College of Science and Technology, University of London and a master’s degree in business administration from Harvard Business School.

Qualifications

The Board concluded that Mr. Hassan should serve on the Board based on his global experience as a public company chief executive officer, his particular knowledge and experience in the healthcare and pharmaceutical industries, including overseeing businesses with significant research and development operations, his diversified financial and business expertise, as well as prior public company board experience. Given his financial and leadership experience, Mr. Hassan has been determined to be an Audit Committee financial expert by our Board.

LOGOï 2020 Proxy Statement    13


Item 1 — Election of Directors

 

 

Charles M. Holley, Jr.      

 

LOGO

 

 

Director since:2017

 

Age:6365

 

Committees:

  Audit (Chair)

  Executive

  Governance and Nominating

 

Other Public Company Boards:

  Carrier Global Corporation

  Phillips 66

 

Audit Committee financial expert

 

   

 

Charles M. Holley, Jr. is the former Executive Vice President and Chief Financial Officer forWal-Mart Stores, Inc., or Walmart, where he served from 2010 to 2015 and as Executive Vice President in January 2016. Prior to this, Mr. Holley served as Executive Vice President, Finance and Treasurer of Walmart from 2007 to 2010. From 2005 to 2006, he served as Senior Vice President. Prior to that, Mr. Holley was Senior Vice President and Controller from 2003 to 2005. Mr. Holley served various roles inWal-Mart International from 1994 through 2002. Prior to this, Mr. Holley served in various roles at Tandy Corporation. He spent more than ten years with Ernst & Young LLP. Mr. Holley was an Independent Senior Advisor, U.S. CFO Program, at Deloitte LLP, a privately-held provider of audit, consulting, tax, and advisory services, from 2016 to 2019.

 

Mr. Holley has been a director of Phillips 66 an energy manufacturing and logistics company, since October 2019 and serves on the Audit and Finance, and Public Policy and Sustainability Committees. In connection with the 2020 spin-off from United Technologies CorporationMr. Holley has also been a director of Carrier Global Corporation, a provider of heating, ventilating, air conditioning (HVAC), refrigeration, fire, and security solutions, Mr. Holley has been appointedsince 2020 and chairs the Audit Committee and serves as a directormember of Carrier. Hethe Compensation Committee. Mr. Holley serves on the Advisory Council for the McCombs School of Business at the University of Texas at Austin and the University of Texas Presidents’ Development.Development Board.

 

Qualifications

 

The Board concluded that Mr. Holley should serve on the Board based on his experience as a chief financial officer of a global public company, his financial acumen, and his management and leadership skills. Given his financial and leadership experience, Mr. Holley has been determined to be an Audit Committee financial expert by our Board.

 

12    LOGO ï 2022 Proxy Statement


Item 1 — Election of Directors

S. Omar Ishrak

LOGO

Director since:2021

Age:66

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Intel Corporation

  Compute Health Acquisition Corporation

S. Omar Ishrak has served as a director of the Company since July 2021. Dr. Ishrak was first identified to the Governance and Nominating Committee as a potential director candidate by the Chairman and certain non-employee members of the Board, including our lead independent director. He is the former Executive Chairman and Chairman of the Board of Directors of Medtronic plc, or Medtronic, a global medical technology company. Dr. Ishrak served as the Chief Executive Officer of Medtronic from 2011 to April 2020 and was Executive Chairman until December 2020. Prior to joining Medtronic, he served as President and Chief Executive Officer of GE Healthcare Systems, a provider of medical imaging and diagnostic technology and a division of GE Healthcare, from 2009 to 2011. Dr. Ishrak was President and Chief Executive Officer of GE Healthcare Clinical Systems from 2005 to 2008 and President and Chief Executive Officer of GE Healthcare Ultrasound and BMD from 1995 to 2004.

Dr. Ishrak has been a director of Intel Corporation, a multinational corporation and technology company, since 2017 and Chairman of its Board since 2020, serving as a member of the Compensation Committee and Corporate Governance and Nominating Committee. He has served as Chairman of the Board of Directors of Compute Health Acquisition Corporation, a special purpose acquisition company, since 2021. Dr. Ishrak is a member of the Board of Trustees of the Asia Society, an educational organization dedicated to promoting mutual understanding and strong partnerships between Asia and the U.S. Since 2021, Dr. Ishrak has been a senior advisor to Blackstone Life Sciences, a segment of Blackstone Inc. that invests in the biopharmaceutical and medical technology industries.

Dr. Ishrak was inducted into the American Institute for Medical and Biological Engineering College of Fellows in 2016, elected as a Fellow of King’s College London in 2017, inducted into the Bakken Society in 2020, and elected to the National Academy of Engineering in 2020. Dr. Ishrak received his undergraduate degree and doctorate from the University of London, King’s College.

Qualifications

The Board concluded that Dr. Ishrak should serve on our Board based on Dr. Ishrak’s board and senior executive-level expertise, including his experience as chief executive officer of a global, highly regulated public company in the healthcare industry, his extensive background in medical technologies, manufacturing, international expertise and interest in Asia, and his management and leadership skills.

LOGO ï 2022 Proxy Statement13


Item 1 — Election of Directors

 

Tyler Jacks

 

 

LOGO

 

 

Director since:2012

 

Age:5961

 

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

 

Other Public Company Boards:

  Thermo Fisher Scientific, Inc.

   

 

Tyler Jacks joined the faculty of Massachusetts Institute of Technology, or MIT, in 1992 and is currently the David H. Koch Professor of Biology, a position he has held since 2007, and founding director of the David H. Koch Institute for Integrative Cancer Research, which brings together biologists and engineers to improve detection, diagnosis and treatment of cancer, a position he has held since 2007.having served as director from 2007 to 2021. Since 2021, Dr. Jacks has beenserved as President and director of Break Through Cancer, a foundation bringing together multidisciplinary cancer research teams selected from across five participating institutions.(1) Dr. Jacks was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, since 1994.from 1994 until 2021.

 

Dr. Jacks has been a director of Thermo Fisher Scientific, Inc., a life sciences supply company, since 2009, serving onas the Chair of its Science and Technology Committee and as a member of its Strategy and Finance Committee and its scientific advisory board and chairing its Science and Technology Committee.board. In 2006, heco-founded T2 Biosystems, Inc., a biotechnology company, and served on its scientific advisory board until 2013. Dr. Jacks has served on the scientific advisory board of SQZ Biotech,Biotechnologies Company, a privately-held biotechnology company, since 2015. Dr. Jacks served on the scientific advisory board of Aveo Pharmaceuticals Inc., a biopharmaceutical company, from 2001 until 2013. In 2015, Dr. Jacks founded Dragonfly Therapeutics, Inc., a privately-held biopharmaceutical company, and serves as Chair of its scientific advisory board. HeIn 2011, he was appointed to the National Cancer Advisory Board, which advises and assists the Director of the National Cancer Institute with respect to the National Cancer Program, in 2011 and served as Chair until 2016. In 2016, Dr. Jacks was named to a blue ribbon panel of scientists and advisors established as a working group of the National Cancer Advisory Board and served asco-Chair advising the Cancer MoonshotSM Task Force. Dr. Jacks was a director of MIT’s Center for Cancer Research from 2001 to 2007 and received numerous awards including the Paul Marks Prize for Cancer Research and the American Association for Cancer Research Award for Outstanding Achievement. He was elected to the National Academy of Sciences as well as the National Academy of Medicine in 2009 and received the MIT Killian Faculty Achievement Award in 2015. Dr. Jacks received an undergraduate degree from Harvard University and his doctorate from the University of California, San Francisco.

Qualifications

The Board concluded that Dr. Jacks should serve on the Board based on his extensive scientific expertise relevant to our industry, including his broad experience as a cancer researcher, pioneering uses of technology to study cancer-associated genes, and service on several scientific advisory boards and membership inservice to the National Cancer Advisory Board.

 

(1)

Dana-Farber Cancer Institute, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The University of Texas MD Anderson Cancer Center, Memorial Sloan Kettering Cancer Center, and the Koch Institute for Integrative Cancer Research at MIT.

14    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Item 1 — Election of Directors

 

 

 

 

 

 

Ellen J. Kullman

 

 

LOGO

 

 

Director since: 2016

 

Age:6466

 

Committees:

  Audit

  Governance and Nominating

 

Other Public Company Boards:

  Dell Technologies Inc.

  Goldman Sachs Group, Inc.

 

Audit Committee financial expert

 

   

 

Ellen J. Kullman was appointedis President and Chief Executive Officer of Carbon, Inc., or Carbon, a privately-held 3D printing company, in Novemberhaving held this position since 2019, and has served as a director of Carbon since 2016. She is the former President, Chair and Chief Executive Officer of E.I. du Pont de Nemours and Company, or DuPont, a science and technology-based company, where she served from 2009 to 2015. Prior to this, Ms. Kullman served as President of DuPont from 2008 to 2009. From 2006 through 2008, she served as Executive Vice President of DuPont. Prior to that, Ms. Kullman was Group Vice President, DuPont Safety and Protection. Ms. Kullman has been a director of Goldman Sachs Group, Inc., an investment banking firm, since 2016, serving on its Compensation and Corporate Governance and Nominating Committees and Risk Committees.chairing its Public Responsibilities Committee. Ms. Kullman has been a director of Dell Technologies Inc., a technology company, since 2016, serving on its Audit and Capital Stock Committees.Committee. Ms. Kullman served as a director of United Technologies Corporation, a technology products and services company, from 2011 (and as lead director from 2018) until April 2020,, serving on its Compensation, Finance and Executive Committees.Committees, until its merger with Raytheon Company in 2020. Ms. Kullman served as a director of General Motors, from 2004 to 2008, serving on its Audit Committee.

 

Ms. Kullman has served on the Board of Trustees of Northwestern University since 2016 and on the Board of Overseersis a Trustee Emerita of Tufts University School of Engineering, having served on its Board of Advisors since 2006. She served as Chair of theUS-China Business Council from 2013 to 2015. InSince 2016, Ms. Kullman joinedhas been a member of the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Ms. Kullman received a bachelor of science in mechanical engineering degree from Tufts University and a master’s degree from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Ms. Kullman should serve on the Board based on her lengthy global experience as chief executive officer and board chair at both public and private companies, her management and leadership skills, and her experience with scientific operations, all of which provide valuable insight into the operations of our Company. Given her leadership and financial experience, Ms. Kullman has been determined to be an Audit Committee financial expert by our Board.

 

 

Amy E. Miles

LOGO

Director since: 2020

Age:55

Committees:

  Audit

  Governance and Nominating

Other Public Company Boards:

  Gap Inc.

  Norfolk Southern Corporation

Audit Committee financial expert

Amy E. Miles was the Chief Executive Officer and a director of Regal Entertainment Group, Inc., or Regal Entertainment, a leading theatre exhibition company, having held these positions from 2009 through 2018, and its Chair of the Board from 2015 to 2018. From 2002 to 2009, Ms. Miles served as Executive Vice President, Chief Financial Officer and Treasurer of Regal Entertainment. Ms. Miles also served as Chief Executive Officer of Regal Cinemas, Inc., or Regal Cinemas, from 2009 to 2018, and its Executive Vice President, Chief Financial Officer and Treasurer from 2000 to 2009. Ms. Miles joined Regal Cinemas in 1999 as Senior Vice President of Finance. Previously, Ms. Miles was with Deloitte & Touche, LLP and PricewaterhouseCoopers LLP.

Ms. Miles has been a director of Norfolk Southern Corporation, a transportation company, since 2014, and serves on the Executive Committee, the Governance and Nominating Committee, and chairs the Audit Committee, and, beginning in May 2022, will serve as non-executive Chair of the board and cease serving as Chair of the Audit Committee, but will remain a member of the Audit Committee. Ms. Miles has been a director of The Gap, Inc., an apparel retail company, since 2020, and chairs the Audit and Finance Committee. Ms. Miles was a director of National CineMedia, Inc., a cinema advertising company, from 2011 to 2015. She was a director of Townsquare Media, Inc., a radio, digital media, entertainment, and digital marketing solutions company, from 2014 until 2016.

Ms. Miles has been a director of ASM Global, a privately-held entertainment and venue management company, since 2019. Ms. Miles serves on the boards of trustees of the University of Tennessee and the Boys and Girls Club of Eastern Tennessee.

Qualifications

The Board concluded that Ms. Miles should serve on our Board based on Ms. Miles’ board and senior executive-level expertise, including her experience as chief executive officer and chief financial officer of a large public company and her extensive finance, accounting, and management expertise in marketing and strategic planning, and public board experience. Given her leadership and financial experience, Ms. Miles has been determined to be an Audit Committee financial expert by our Board.

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Item 1 — Election of Directors

Ronald D. Sugar

 

LOGO

 

Director since:2010

 

Age:7173

 

Committees:

  Corporate Responsibility and Compliance (Chair)

  Executive

  Governance and Nominating

 

Other Public Company Boards:

  Air Lease Corporation (will not be standing forre-election)

Apple Inc.

  Chevron Corporation

  Uber Technologies, Inc.

   

 

Ronald D. Sugar is the retired Chairman of the Board and Chief Executive Officer of Northrop Grumman Corporation, a global aerospace and defense company, having held these posts from 2003 through 2009.

 

Dr. Sugar has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2005, serving as the lead director and on the Management Compensation Committee and chairing the Board Nominating and Governance Committee. Dr. Sugar has been a director of Apple Inc., a manufacturer and seller of, among other things, personal computers, mobile communication and media devices, since 2010, chairing the Audit and Finance Committee. Dr. Sugar has been a director of Air Lease Corporation, an aircraft leasing company, since 2010, chairing the Compensation Committee and serving on the Nominating and Corporate Governance Committee, and will not be standing for election to the board of Air Lease Corporation at the next annual meeting of stockholders expected to occur in May 2020. Dr. Sugar has been a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, since 2018, serving as the Chair of the board of directors and chairing the Nominating and Governance Committee and serving on the Compensation Committee. Dr. Sugar served as a director of Air Lease Corporation, an aircraft leasing company, from 2010 to 2020, and chaired its Compensation Committee and served on the Nominating and Corporate Governance Committee. Since 2010, he has been a senior advisor to Ares Management LLC, a privately-held asset manager and registered investment advisor. In 2014, Dr. Sugar joined the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Dr. Sugar is a member of the National Academy of Engineering, trustee of the University of Southern California, member of the UCLA Anderson School of Management Board of Advisors, and director of the Los Angeles Philharmonic Association.

 

Qualifications

 

The Board concluded that Dr. Sugar should serve on our Board because of Dr. Sugar’s board and senior executive-level expertise, including his experience as chief executive officer and board chair of a large, highly regulated, public company and his insight in the areas of operations, government affairs, science, technology and finance.

 

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Item 1 — Election of Directors

 

R. Sanders Williams

 

LOGO

 

Director since:2014

 

Age:7173

 

Committees:

  Corporate Responsibility and Compliance

  Governance and Nominating

 

Other Public Company Boards:

  Laboratory Corporation of America Holdings

  Tenaya Therapeutics, Inc.

 

   

 

R. Sanders Williams is the President Emeritus of Gladstone Institutes, anon-profit biomedical research enterprise, having served in this position since 2018, and was the Chief Executive Officer of the Gladstone Foundation, anot-for-profit organization supporting the Gladstone Institutes during 2018. Dr. Williams has served as Professor of Medicine at Duke University since 2018 and, from February 2021 to January 2022, acted as Interim Vice President for Research and Innovation. He has been a Professor of Medicine at the University of California, San Francisco since 2010, and Professor of Medicine at Duke University since 2018.2010. Dr. Williams was both President of Gladstone Institutes and its Robert W. and Linda L. Mahley Distinguished Professor of Medicine, from 2010 to 2017. Prior to this, Dr. Williams served as Senior Vice Chancellor of the Duke University School of Medicine from 2008 to 2010 and Dean of the Duke University School of Medicine from 2001 to 2008. He was the founding Dean of theDuke-NUS Graduate Medical School, Singapore, from 2003 to 2008 and served on its Governing Board from 2003 to 2010. From 1990 to 2001, Dr. Williams was Chief of Cardiology and Director of the Ryburn Center for Molecular Cardiology at the University of Texas, Southwestern Medical Center.

 

Dr. Williams has been a director of the Laboratory Corporation of America Holdings, a diagnostic technologies company, since 2007, serving on the Audit and Compensation CommitteesCommittee and chairing the Quality and Compliance Committee. Since 2016, Dr. Williams also has served as a director of Tenaya Therapeutics, Inc., a biotechnology company, chairing the Compensation Committee. Tenaya Therapeutics, Inc. was a privately-held company until July 2021 when it became publicly traded. Dr. Williams was a director of Bristol-Myers Squibb Company, a pharmaceutical company, from 2006 until 2013. Dr. Williams has served on the board of directors of the Gladstone Foundation, anon-profit institution that is distinct from Gladstone Institutes, since 2012 and on the board of directors of Exploratorium, anon-profit science museum and learning center located in San Francisco, from 2011 until 2018.2012. Dr. Williams was elected to the National Academy of Medicine in 2002. Dr. Williams received his undergraduate degree from Princeton University and his medical doctorate from Duke University.

Qualifications

The Board concluded that Dr. Williams should serve on the Board because of his broad medical and scientific background, including his leadership roles in domestic and academic science settings, his deep experience in cardiology, oversight of governance of multi-hospital healthcare provider systems, leadership and development of international medical programs in Asia, and prior industry board experience.

 

 

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE ABOVE 1112 NAMED NOMINEES.

 

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Corporate Governance

 

 

 

 

 

Corporate Governance

 

Board of Directors Corporate Governance Highlights

 

Our Board of Directors, or Board, is governed by our Amgen Board of Directors Corporate Governance Principles which are amended from time to time to incorporate certain current best practices in corporate governance. Our Corporate Governance Principles may be found on our website atwww.amgen.com(1) and are available in print upon written request to the Company’s Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799. The Board’s corporate governance practices and stockholder rights include the following:

Board Governance Practices

 

 

Lead Independent Director. The independent members of the Board elect a lead independent director on an annual basis. The lead independent director has robust responsibilities and authorities as discussed below. Robert A. Eckert currently serves as our lead independent director.

 

 

Regular Executive Sessions of Independent Directors.Our independent directors meet privately on a regular basis. Our lead independent director presides at such meetings.

 

 

Board Access to Management. We afford our directors ready access to our management. Key members of management attend Board and committee meetings to present information concerning various aspects of the Company, its operations, and results. The Corporate Responsibilityresults, and Compliance Committee, or Compliance Committee, members also have regular meetings in executive sessionsessions with our Chief Compliance Officer,the Board and the Audit Committee members have regular meetings in executive session with our internal and external auditors and separate meetings in executive session with our head of Corporate Audit.committees.

 

 

Board Authority to Retain Outside Advisors. Our Board and its committees have the authority to retain outside advisors.independent advisors and counsel. The Audit Committee has the sole authority to appoint, compensate, retain, and oversee the independent registered public accountants. The Compensation and Management Development Committee, or Compensation Committee, has the sole authority to appoint, compensate, retain, and oversee compensation advisors for senior management compensation review. The Governance and Nominating Committee, or Governance Committee, has the sole authority to appoint, retain, and replace search firms to identify director candidates and compensation advisors for our directors’ compensation review.

 

 

Independent Board Members on Key Standing Committees. The Board has four key standing committees: the Governance Committee; Audit Committee; Corporate Responsibility and Compliance Committee, or Compliance Committee; and Compensation Committee. Each member on key standing committees has been determined by the Board to be independent

under The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission, or SEC.

Regular Board and Committee Evaluations. The Board and the Audit, Compensation, Compliance, and Governance Committees each haveconduct an annual evaluation process. We provide more information regarding the Board and committee evaluations on page 24.27.

 

Management Succession Oversight. Our Board oversees Chief Executive Officer, or CEO, and senior management succession planning. Directors engage with potential CEO, executive, and senior management successors at Board and committee meetings. All independent members of the Board are invited to attend the Compensation Committee session on succession. Our Board also establishes steps to address succession to respond to unexpected vacancies in the event of an emergency.

 

 

Solicitation of Stockholder Perspectives. The Board believes that engagement with stockholders is a source of valuable information and perspectives on the Company. The Board has requested that management solicit input from investors on behalf of the Board and the lead independent director has also met directly with stockholders when appropriate. We provide more information regarding theour stockholder engagement program on page 46.pages 31 and 51.

 

 

Majority Approval Required for Director Elections. If an incumbent director up forre-election at a meeting of stockholders fails to receive a majority of the votes cast in favor for his or her election in an uncontested election, the Board will adhere to the director resignation policy as provided in our Amended and Restated Bylaws of Amgen Inc., or Bylaws.

 

 

Director Limitation on Number of Boards. A director who is currently serving as our CEO should not serve on more than two outside public company boards. No director should serve on more than five outside public company boards. As part of its nominating process, the Governance Committee conducts an annual review of director commitment levels and shares its findings with the Board.

 

 

Board Refreshment and Tenure.Continuous OurBoard Refreshment. We have added seven new members to our Board since 2015 and our average Board tenure is approximately five and a half years for our director nominees.6 years.

 

 

Director Retirement Age. The Board has established a retirement age of 75. A director is expected to retire from the Board on the day of the annual meeting of stockholders following his or her 75th birthday.

 

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Corporate Governance

 

Director Changes in Circumstances Actively Evaluated. If a director has a substantialsignificant change in principal business or professional affiliation or responsibility, including a change in principal occupation, he or she shall offer his or her resignation to the chairmanChair of the Governance Committee. The Governance Committee then determines whether to accept the resignation based on what it believes to be in the best interests of the Company and our stockholders. Directors notify the Chair of the Governance Committee prior to accepting an invitation to serve on a public or private company board to permit the Governance Committee to evaluate the relationship for a potential conflict of interest and to confirm that the director continues to have time available to perform his or her duties.

 

 

Director Outside Relationships RequirePre-Approval. Without the prior approval of disinterested members of the Board, directors should not enter into any transaction or relationship with the Company in which they will have a financial or a personal interest or any transaction that otherwise involves a conflict of interest.

 

 

Active Management of Director Conflicts of Interest. If an actual or potential conflict of interest arises for a director or a situation arises giving the appearance of an actual or potential conflict, the director must promptly inform the Chairman of the Board or the chairmanChair of the Governance Committee. All directors are expected to recuse

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Corporate Governance

themselves from any discussion or decision found to affect their personal, business, or professional interests.

Stockholder Rights

 

Single Class of Shares. We have a single class of shares with equal voting rights. One share equals one vote.

 

Proxy Access. Our Bylaws permit proxy access for director nominations. Eligible stockholders with an ownership threshold of 3% who have held their shares for at least 3 years and who otherwise meet the requirements set forth in our Bylaws may have their nominees up to the number of directors constituting the greater of 20% of the total number of directors or two nominees of our Board included in our proxy materials. Up to 20 eligible stockholders may group together to reach the 3% ownership threshold. In the course of designing our proxy access provisions, we carefully considered each element in the interest of our stockholders as a whole, including that the number of stockholders who may group together (20) would afford those stockholders likely to utilize proxy access with the opportunity to do so.

 

Action by Written Consent. Our Amgen Inc. Restated Certificate of Incorporation permits stockholders to act by written consent in lieu of a meeting upon the request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements of our Certificate of Incorporation.

 

 

Special Meetings. Our Bylaws permit stockholders to request that the Company call a special meeting upon the written request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements set forth in our Bylaws.

 

 

No Supermajority Vote Provisions in Certificate of Incorporation or Bylaws.Provisions. We have a simple majority voting standard to amend our Certificate of Incorporation and Bylaws.

 

 

No Poison Pill. We do not have a shareholder rights plan, or poison pill.

 

 

Leadership Structure

 

 

Our current leadership structure and governing documents permit the roles of Chairman and CEO to be filled by the same or different individuals. The Board has currently determined that it is in the best interests of the Company and our stockholders to have Robert A. Bradway, our CEO and President, serve as Chairman, coupled with an active lead independent director. As such, Mr. Bradway holds the position of Chairman, CEO, and President, and Mr. Eckert serves as the lead independent director.

Corporate Governance Structure. The Board believes our corporate governance structure, with its strong emphasis on Board independence, an active lead independent director, and strong Board and committee involvement, provides sound and robust oversight of management.

Annual Evaluation of Leadership Structure and Annual Election of Lead Independent Director. The Board evaluates, considers, and discusses the leadership structure every year.annually. As part of this annual evaluation process, the Board reviews its leadership structure, andincluding whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders. The Board also considers:

 

The effectiveness of the policies, practices, and people in place at the Company to help ensure strong, independent Board oversight;

 

The Company’s performance and the effect the leadership structure could have on its performance;

 

The Board’s performance and the effect the leadership structure could have on the Board’s performance;

 

The Chairman’s performance in the role;

 

The lead independent director’s performance in the role;

The views of the Company’s stockholders; and

The practices at other companies and trends in governance.

IfIn the circumstance that the Board determines that it remains in the best interests of the Company and its stockholders that the CEO serve as chairman, the lead independent director is considered and elected byChairman, the independent members of the Board then elects a lead independent director from the independent members of the Board. The last review was completed in March 2022, and as a result of such review, the Board has determined that it continues to be in the best interests of the Company and our stockholders to have Robert A. Bradway, our CEO and President, serve as Chairman, coupled with an active lead independent director. As such, Mr. Bradway holds the position of Chairman, CEO, and President, and Mr. Eckert serves as the lead independent director.

Overview of Lead Independent Director Responsibilities.The responsibilities of the lead independent director are well-defined. The lead independent director engages in regular communication betweenwith the independent directors, and Mr. Bradway, keepingincluding in independent directors sessions. The lead independent director keeps Mr. Bradway apprised of any concerns, issues, or determinations made during the independent sessions, and consults with Mr. Bradway on other matters pertinent to the Company and the Board. The lead independent director’s responsibilities outlined in our Corporate Governance Principles include:

Approving meeting agendas for the Board;

Assuring that there is sufficient time for discussion of all meeting agenda items;

Previewing the information to be provided to the Board;

Having the authority to call meetings of the independent directors;

Organizing and leading the Board’s evaluation of the CEO;

Serving as a liaison between the Chairman and the independent directors;

Leading the Board’s annual self-assessment;

Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

 

 

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Corporate Governance

 

 

 

 

 

Lead Independent Director Responsibilities

The lead independent director’s responsibilities outlined in our Corporate Governance Principles include:

   Approving meeting agendas for the Board;

   Assuring that there is sufficient time for discussion of all meeting agenda items;

   Previewing the information to be provided to the Board;

   Having the authority to call meetings of the independent directors;

   Organizing and leading the Board’s evaluation of the CEO;

   Serving as a liaison between the Chairman and the independent directors;

   Leading the Board’s annual self-evaluation;

   Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

   Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

In addition to the responsibilities outlined above, theour lead independent director:director also:

 

Meets with the Chairman prior to each regular meeting of the Board and its committees to discuss, provide input on, and approve the agendas;

 

With the Chairman, determines presenters for attendance atwho attends Board meetings;meetings, such as members of management or outside advisors, and presenters;

 

Hasone-on-one discussions with each independent director, including as part of the Board’s annual evaluation process;

 

Attends all committee meetings, including those committees for which he is not a member (at his discretion) and is provided withhas access to all committee materials;

 

Has the authority to engage independent consultants;

 

Is regularly apprised of inquiries from stockholders;

 

Interviews Board candidates; and

 

Has an increased role in crisis and risk management, as appropriate.

Independent Directors Sessions. A meeting of the independent directors is scheduled at every regular Board meeting and the independent directors meet in an executive session without Mr. Bradway to review matters, including Company performance, management effectiveness, proposed programs and transactions, and the Board meeting agenda items. These independent sessions are organized and chaired by our lead independent director and our lead independent director provides direct feedback to Mr. Bradway after these executive sessions.

Independent Committee Leadership. The Audit, Compensation, Compliance, and Governance Committees are each composed solely of,

and led by, independent directors and provide independent oversight of management.management and its Board-delegated duties. In addition:

 

Each committee chairChair meets with management in advance of meetings to review and refine agendas, add topics of interest, and review and comment on materials to be delivered to the committee;

 

Every independent director has access to all committee materials;

 

Each committee chairChair provides a report summarizing committee meetings to the full Board at each regular meeting of the Board;

 

Each committee meeting includes adequate time for executive session and the committees meet in executive session on a regular basis with no members of management present (unless otherwise requested by the committee); and

 

Each committee effectively manages its Board-delegated duties and communicates regularly with the Chairman, lead independent director, the Board, and members of management.

Furthermore, the Compensation Committee has an effective process for succession planning and for monitoring and evaluating Mr. Bradway’s compensation and performance.

Lead Independent Director. Following the annual re-evaluation of our corporate governance structure, Mr. Eckert has been elected annually as the lead independent director each year since theour May 2016 annual meeting of stockholders and wasre-elected by our Board on March 4, 20202, 2022 to continue to serve as lead independent director subject to hisre-election to the Board by our stockholders at the 20202022 Annual Meeting.

Benefits of Combined LeadershipCorporate Governance Structure. The Board believes our corporate governance structure, with its strong emphasis on Board independence, an active lead independent director, and strong Board and committee involvement, provides sound and robust oversight of management.

Benefits of Combined Leadership Structure. Following the annual evaluation of the governance structure, the Board continues to believe that the Company and our stockholders have beenare best served by having Mr. Bradway in the role of Chairman (subject to his re-election to the Board) and CEO for the following reasons:

 

Mr. Bradway is most familiar with our business and the unique challenges we face. Mr. Bradway’sday-to-day insight into our challenges facilitates a timely deliberation by the Board of important matters.

 

Mr. Bradway has and will continue to identify agenda items and lead effective discussions on the important matters affecting us. Mr. Bradway’s knowledge and extensive experience regarding our operations and the highly-regulated industries and markets in which we compete position him to identify and prioritize matters for Board review and deliberation.

 

As Chairman and CEO, Mr. Bradway serves as an important bridge between the Board and management and provides critical leadership for carrying out our strategic initiatives and confronting our challenges. The Board believes that Mr. Bradway brings a unique, stockholder-focused insight to assist the Company to most effectively execute its strategy and business plans to maximize stockholder value.

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Corporate Governance

unique, stockholder-focused insight to assist the Company to most effectively execute its strategy and business plans to maximize stockholder value.

 

The strength and effectiveness of the communications between Mr. Bradway as our Chairman and Mr. Eckert as our lead independent director result in comprehensive Board oversight of the issues, plans, and prospects of our Company.

 

This leadership structure provides the Board with more complete and timely information about the Company, a unified structure and consistent leadership direction internally and externally and provides a collaborative and collegial environment for Board decision making.

consistent leadership direction internally and externally and provides a collaborative and collegial environment for Board decision making.

Flexibility of the Leadership Structure. The Board is committed to high standards of corporate governance. The Board values its flexibility to select from time to time, aits optimal leadership structure that is most able to best serve the Company’s and stockholders’ best interests based on the qualifications of individuals available, and circumstances existing at the time.time, and Company’s particular needs. As such, the Board annually evaluates whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders.

 

 

The Board’s Role in Risk Oversight

Our Board oversees an enterprise-wide approach to risk management, which is designed to support execution of our strategy and achievement of the Company’s objectives to improve long-term operational and financial performance and enhance stockholder interests. Our Board believes that a fundamental part of risk management is understanding the risks that we face, adopting appropriate controls and mitigation activities for such risks, monitoring these risks, and responding to emerging developments for such risks.

We have a Company-wide Enterprise Risk Management, or ERM, program, to identify, assess, manage, report, and monitor enterprise-level risks that may affect our ability to achieve the Company’s objectives. The ERM program is overseen by our Executive Vice President and Chief Financial Officer and chaired by our Chief Audit Executive. Annually, we evaluate the greatest risks to our business, their underlying risk drivers, and the associated mitigation activities, maturity, and controls. Our Enterprise Risk Council, a cross-functional group of the Company’s business leaders representing all key business functions, works to identify and assess risks that meet the pre-established criteria constituting an enterprise-level risk, and confirms that there is clear accountability and appropriate mitigation plans are in place, including monitoring and reporting. Additionally, emerging risks that do not rise to the level of enterprise-level risks, are assessed, discussed, and actively managed and monitored. We believe that the areas of risk that are fundamental to the success of our enterprise and rise to enterprise-level risks include the areas of product development, safety and surveillance, supply and quality, value (which includes pricing) and access, sales and promotion, business development, as well as protecting our assets (financial, intellectual property, and information, including cybersecurity), all of which are managed by senior executive management reporting directly to our CEO.

The enterprise-level risks are overseen by the Board and the appropriate Board committee (as discussed below). The Board receives regular risk reporting from senior management, including an annual detailed review of the ERM program and key enterprise-level and emerging risks, as well as during the Board’s annual strategic planning process, annual budget reviews and approvals, capital plan review and approval, and through reviews of compliance issues at the applicable committees of our Board, as appropriate. For example, the risks associated with COVID-19 have the potential to affect areas of enterprise-level risk overseen by our Board, Audit Committee, Compensation Committee, and Compliance Committee and, as such, our risk mitigation plans and the effects of COVID-19 have been a topic regularly brought to and reviewed by the Board and its committees. For topics allocated to specific committees for their oversight, such as antitrust and competition regulation that is an area of the Compliance Committee’s responsibilities (as discussed below), the Compliance Committee Chair oversees the Compliance Committee’s annual calendar and meeting agendas to determine that the Company’s activities in support of its compliance with antitrust and competition regulation are assessed regularly, including a full annual review that includes Amgen’s policies, processes, and training to support such compliance, as well as regular updates of any significant industry developments at each Compliance Committee meeting. As is the practice for each of our committee Chairs, the Compliance Committee Chair reports out on these and other activities to the Board for its information and oversight at each regular Board meeting.

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Corporate Governance

 

 

 

 

 

The Board’s Role in Risk Oversight

Our Board oversees an enterprise-wide approach to risk management, which is designed to support the achievement of the Company’s objectives, including its strategic priorities to improve long-term operational and financial performance and enhance stockholder value. Our Board believes that a fundamental part of risk management is understanding the risks that we face, monitoring these risks, and adopting appropriate controls and mitigation activities for such risks. We believe that the risk management areas that are fundamental to the success of our enterprise include the areas of product development, safety and surveillance, supply and quality, value and access, sales and promotion, business development, as well as protecting our assets (financial, intellectual property, and information (including cybersecurity)), all of which are managed by senior executive management reporting directly to our CEO.

We have implemented an Enterprise Risk Management, or ERM, program, which is a Company-wide effort to identify, assess, manage, report, and monitor enterprise risks that may affect our ability to

achieve the Company’s objectives. The ERM program involves our Board and management and is overseen by one of our senior executive officers. Enterprise risks are identified and managed by management and the business functions and, as discussed below, are overseen by the Board or the appropriate Board committee. Our Board has ultimate oversight responsibility for the risk management process. The Board discusses enterprise risks with our senior management on a regular basis, including as a part of its annual strategic planning process, annual budget review and approval, capital plan review and approval, and through reviews of compliance issues in the applicable committees of our Board, as appropriate. For example, the potential risk associated with our pricing and access strategy and approach is an area of enterprise risk with respect to which our Board and Compliance Committee receive regular updates. All risk areas are appropriately monitored by management and all risk areas that could lead to business disruption, including the potential to cause severe financial or reputational harm, report to the Board regularly oras-needed, and are subject to appropriate Board oversight.

Each Board Committeecommittee has primary risk oversight responsibility that is aligned with its areas of focus. At each regular meeting, or more frequently as needed, the Board receives and considers committee reports, whichand such reports may provide additional detail on risk management issues and management’s response.

 

  Committee

  

Primary Risk Oversight Responsibility

 

  Governance and Nominating

  

   Oversees governance risk, including the assessment of each member of the Board’s independence, as well as the compliance with our Corporate Governance Principles and Board of Directors’ Code of Conduct. Also oversees Board and committee evaluations and Board succession.

 

 

  Audit

  

   Oversees internal controls over financial reporting, and overseesas well as internal audit and independent registered public accountants, as well as financial risk, such as capital risk, tax risk, sourcing risk, and financial compliance risk.

 

 

  Compensation and Management Development

  

   Oversees human capital management, as well as executive talent management, development, and succession planning. Also oversees our compensation policies and practices and incentive program administration and design, including whether such policies, practices, and incentive programs balance risk-taking and rewards in an appropriate manner (as discussed further below), align with stockholders’ interests, and are consistent with emerging best practices. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities, previously overseen by the Compliance Committee, moved to the Compensation Committee.

 

 

  Corporate Responsibility and Compliance

  

   Overseesnon-financial compliance risk, such as regulatory risks associated with the requirements of the FederalU.S. federal health care program,programs, Food and Drug Administration and other regulatory agencies, and risks associated with privacy, trade compliance, antitrust and competition, anti-corruption,anti-bribery and anti-corruption), information systems and security (including cybersecurity), pricingvalue (which includes pricing) and access, government affairs, aspects of labor and employment activities and diversity, inclusion, and belonging(1), aspects of environmental sustainability, social responsibility, and corporate governance, or ESG (including diversityenvironmental sustainability, corporate philanthropy, and inclusion)pricing philosophy and practice), and our reputation. Also oversees staff member compliance with the global Code of Conduct.

 

 

COVID-19 Impacts to Enterprise Risk and Our Response. The far-reaching effects of COVID-19 prompted the Company to consider enterprise risk focused on rare, but high-impact events, such as global pandemics. Our business resilience program is designed to enable us to effectively prepare for and respond to crisis incidents at the global, regional, and local levels. Since the beginning of the pandemic in early 2020, we have activated appropriate crisis management and business

continuity plans and responded to the challenges presented to the operations of our business and focused on the experiences of our customers, patients, staff members, and communities. Multiple enhancements were made to our overall resilience during this pandemic, including investments in systems, automation, and innovation designed to support our remote work environment.

(1)

Responsibility of the Compliance Committee in 2021. Responsibility for these activities moved to the Compensation Committee for 2022.

 

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Corporate Governance

 

 

 

 

 

Responding to COVID-19

In the second year of the pandemic, we continued to focus on the health and safety of our staff members and the effective operation of our business, while undertaking activities to help address the pandemic, such as manufacturing COVID-19 antibody material with Eli Lilly & Company.

Our Employees. Creating a safe and healthy workplace for our staff is a priority at Amgen. Staff member access to our facilities has been in accordance with applicable government health and safety protocols and guidance issued in response to the COVID-19 pandemic and we have taken additional safety measures, including implementing occupancy limits, restricting business travel, providing personal protective equipment, temperature screening, and COVID-19 testing. In 2021, we required staff members in the U.S. and Puerto Rico to be fully vaccinated against COVID-19.(1)

Supply of Our Medicines to Patients. To date, our remote working arrangements have not significantly affected our ability to maintain

critical business operations. We have been able to serve physicians and patients as we have avoided disruptions to delivery and shortages of our supply of medicines.

Helping Our Communities. Amgen and The Amgen Foundation, Inc., a separate legal entity entirely funded by Amgen (Amgen Foundation), have been deeply engaged with our communities during the COVID-19 pandemic. For example, since the start of the pandemic, we committed $12.5 million to support local emergency response efforts in our U.S. and international communities, patient-focused organizations mounting their own response efforts, and international relief efforts by Direct Relief and International Medical Corps. Additionally, the free online learning programs supported by the Amgen Foundation, including LabXchange and the Khan Academy, have helped students continue their science education during school closures.

Codes of Ethics and Business Conduct

 

 

Our Board has adopted two codes of business conduct and ethics, one– the Amgen Board of Directors’ Code of Conduct that applies to our Board and a secondglobal Code of Conduct that applies to our Board, all our staff, and others conducting business on our behalf. Annual training on the global codeCode of conductConduct is required and our Board participates in such training. We also have a code of ethics for senior financial officers. To view our

codes of business conduct and ethics, please visit

our website atwww.amgen.com.(2) We intend to disclose any future amendments to certain provisions of our codes of business conduct and ethics, or waivers of such provisions, applicable to our directors and executive officers on our website.website if such disclosure is required by SEC or NASDAQ rules. There were no waivers of any of our codes of business conduct or code of ethics in 2019.2021.

 

 

Board Meetings

 

 

The Board held 67 meetings in 20192021 and all of the directors attended at least 75% of the total number of meetings of the Board and committees on which they served. S. Omar Ishrak was appointed to the Board effective in July 2021 and attended all of the meetings of the Board and of the committees on which he served after the date of his

appointment. It is the Company’s policy that all current

directors attend our annual meetings of stockholders barring unforeseen circumstances or irresolvable conflicts. Each of our directors serving at the time of our 2021 Annual Meeting were present at our 20192021 Annual Meeting.

 

 

Communication Withwith the Board

 

 

Our annual meeting of stockholders provides an opportunity each year for stockholders to ask questions of our lead independent director and other members of the Board on appropriate matters. In addition, stockholders may communicate in writing with any particular director, any committee of the Board, or the directors as a group, by sending such written communication to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799. Copies of written communications received at such address will be provided to the Board or the relevant director unless such communications are considered, in the reasonable judgment of our Secretary, to be inappropriate for submission to the intended recipient(s). Examples of stockholder communications that would be considered inappropriate for submission to the Board include, without

without limitation, customer complaints, solicitations, communications that do not relate directly or indirectly to our business, or communications that relate to improper or irrelevant topics. The Secretary or his designee may analyze and prepare a response to the information contained in communications received and may deliver a copy of the communication to other Company staff members or agents who are responsible for analyzing or responding to complaints or requests. Communications concerning potential director nominees submitted by any of our stockholders will be forwarded to the chairmanChair of the Governance Committee. For information on our engagement with our stockholders since the 20192021 Annual Meeting, please see page 4651 of our Compensation Discussion and Analysis.

 

(1)

This vaccination requirement did not apply to staff who were unable to receive a COVID-19 vaccine because of qualifying medical or religious reasons.

(2)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Corporate Governance

 

Board Committees and Charters

 

 

The Board has four key standing committees: the Governance Committee; Audit Committee; Compliance Committee; and Compensation Committee. The Compensation Committee has delegated certain responsibilities to an Equity Award Committee. In addition, an Executive Committee of the Board has all of the powers and authority of the Board in the management of our business and affairs, except with respect to certain enumerated matters, including Board composition and compensation, changes to our Certificate of Incorporation, or any other matter expressly prohibited by law or our Certificate of

Certificate of Incorporation. The Executive Committee did not meet in 2019.2021. The Board maintains charters for each of theseits standing committees and these charters are evaluated annually. In addition, the Board has adopted a written set of Corporate Governance Principles and athe Amgen Board of Directors’ Code of Conduct that generally formalize practices we have in place. To view the charters of our standing Board committees, our Corporate Governance Principles, and the Board of Directors’ codeCode of conduct,Conduct, please visit our website atwww.amgen.com.(1)

 

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Corporate Governance

 

 

Governance and Nominating Committee

 

Current Members:

Greg C. Garland (Chair)

Robert A. Eckert

Rebecca M. Henderson

Charles M. Holley, Jr.

Ellen J. Kullman

Amy E. Miles

Ronald D. Sugar

R. Sanders Williams

 

Others Who Served in 2019:

Frank C. Herringer (until retirement at 2019 Annual Meeting)

Number of Meetings Held in 2019:2021: 45

 

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission, or SEC.

    

Description and Key Responsibilities:

 

   Determines Board membership qualifications and maintains, with the approval of the Board, guidelines for selecting nominees to serve on the Board and considering stockholder recommendations for nominees. Such guidelinesThe Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement asAppendix A.

 

   Selects, evaluates, and recommends to the Board nominees to stand for election at the annual meeting of stockholders and to fill vacancies as they arise as more fully described in “Process for Selecting Directors, Director Qualifications, and Board Diversity” below.

 

   Recommends to the Board the appointment of a lead director.

Reviews the performance of the Board and its committees and is responsible for ensuring the availability of an orientation program for new Board members and director education.

 

   Recommends to the Board nominees for appointment as executive officers and certain other officers.

 

   Evaluates and makes recommendations to our Board regarding compensation fornon-employee Board members, including minimum retention and ownership levels of Company stock by Board members. (Any Board member who is also an employee of the Company does not receive separate compensation for service on the Board.)

 

   Monitors the independence of the Board and evaluates questions of possible conflicts of interest of members of the Board.

Oversees the Board’s Corporate Governance Principles and a codethe Amgen Board of conductDirectors’ Code of Conduct applicable to members of the Board and monitors the independenceBoard.

The Governance Committee has authority to delegate these functions to a subcommittee of the Board.its members, but no delegation of authority was made in 2021.

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Corporate Governance

Summary of Current Director Core Experiences and Skills

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, and have gained significant and diverse management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Many of our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees) and an

understanding of corporate governance practices and trends, scientific expertise and healthcare industry experience, and bring unique perspectives to the Board. The Board and the Governance Committee believe the skills, qualities, attributes, experience, and variety of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our Company’s evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director currently represented on our Board. The details of each director nominee’s competencies are included in each director nominee’s biography.

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Experience/Skills Austin Bradway Druker Eckert Garland Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

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Board Tenure 2 <3 Years 4 3-6 Years 4 2 7-9 Years ~6 Years Average Board Tenure Continuous Board Refreshment 7 new directors since 2015 Board Diversity Highlights Gender Diversity Racial/Ethnic Diversity 3 25% Female Directors 9 2 17% Diverse Directors 10 100% Independent directors on key standing committees

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Corporate Governance

In compliance with NASDAQ’s Board Diversity Rule, the table below provides certain highlights of the composition of our Board members and nominees.

Board Diversity Matrix (As of January 20, 2022)
  

Total Number of Directors

 12
   
  Female   Male  
 

Part I: Gender Identity

   

Directors

 3   9  
 

Part II: Demographic Background

   

African American or Black

 1   –  
   

Asian

 –   1  
   

White

 2   8  

Process for Selecting Directors, Director Qualifications, and Board Diversity

 

 

Board Composition. Board composition is one of the most critical areas of focus for the Board. Reflecting our Board’s commitment to refreshment, the Board has appointed fiveseven new directors since 2015, including two additional women as well as those from underrepresented communities, adding critical skills and experience to our Board in furtherance of our strategic priorities.

Our Governance Committee regularly screens and recommends candidates for nomination by the full Board and, among other things, considers feedback received during the annual Board and Committeecommittee evaluation process, investor feedback, our qualification guidelines and skills matrix, director commitment levels (with consideration given to public company leadership roles and outside commitments) and diversity. The Governance Committee will consider recommendations for director candidates made by stockholders and evaluate them using the same criteria as for other candidates.

Director Qualifications and Board Diversity.Our Governance Committee is responsible for determining Board membership qualifications and for selecting, evaluating, and recommending to the Board nominees for annual election to the Board and to fill vacancies as they arise. The Governance Committee reviews regularly and reports to the Board on the composition and size of the Board, and makes recommendations, as necessary, so that the Board reflects the appropriate balance of knowledge, experience, skills, expertise, and diversity advisable for the Board as a whole and maintains at least the minimum number of independent directors required by applicable laws and regulations.regulations, composition requirements of the Audit and Compensation Committees, and reflects the appropriate balance of knowledge, experience, skills, expertise, and diversity advisable and required by applicable laws and regulations for the Board as a whole.

The Governance Committee and Board view diversity as a priority, considers diversity in its determinations, and seeks representation across a range of attributes. Diversity includes race, ethnicity, age, and gender and is also broadly construed to take into consideration many

other factors, including industry knowledge, operational experience, scientific and academic expertise, geography, and personal background. In an effort to best support maintaining and expanding the diversity of our Board, our Governance Committee actively seeks diverse candidates, including women and minority candidates, as part of its search for new directors.

The Governance Committee determines and oversees guidelines for selecting nominees to serve on the Board and for considering

stockholder recommendations for nominees. The Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement asAppendix A.

Among other things, under the Board members shouldof Directors Guidelines for Director Qualifications and Evaluations, each Board member must possess:

 

a demonstrated breadth and depth of management and leadership experience;

A demonstrated breadth and depth of management and leadership experience;

 

financial and/or business acumen or relevant industry or scientific experience;

Financial and/or business acumen or relevant industry or scientific experience;

 

integrity and high ethical standards;

Integrity and high ethical standards;

 

sufficient time to devote to the Company’s business;

Sufficient time to devote to the Company’s business;

 

the ability to oversee, as a director, the Company’s business and affairs for the benefit of our stockholders;

The ability to oversee, as a director, the Company’s business and affairs for the benefit of our stockholders;

 

the ability to comply with the Amgen Board of Directors Code of Conduct; and

The ability to comply with the Amgen Board of Directors’ Code of Conduct; and

 

a

A demonstrated ability to think independently and work collaboratively.

In addition, although the Governance Committee does not maintain a diversity policy, the Governance Committee considers diversity in its determinations. Diversity includes race, ethnicity, age, and gender and is also broadly construed to take into consideration many other factors, including industry knowledge, operational experience, scientific and academic expertise, geography, and personal backgrounds.

 

 

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Corporate Governance

 

 

 

 

 

Continuous Board Refreshment

Our Board is committed to strong refreshment practices to continuously align the composition of the Board and its leadership structure with our long-term strategic needs. The Board, led by the Governance Committee, has an ongoing process for identifying, evaluating, and selecting directors, and these decisions are also informed by the annual Board and committee evaluation process described below. Our Governance Committee uses a variety of methods to help identify potential Board candidates and considers an assessment of current Board skills, background, diversity, independence, experience, tenure, and anticipated retirements to identify gaps that may need to be filled through the Board refreshment process.

 

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Current Board Composition: 7 new directors since 2015 3 women 2 ethnically/racially diverse directors Candidate Pool Sourced, Maintained and Updated Independent Search Firms Stockholders Independent Directors Select Directors Continuous Board Refreshment Governance Committee Review Review by the full Board Recommend Candidates to the Board Consider Guidelines for Director Qualifications and Evaluations (Appendix A) Consider skills matrix Include women and divers director candidates in the list from which director nominees are recommended Review independence and potential conflicts Meet candidates

Director Education

Our Board believes that director education is important to the ability of directors to fulfill their roles and supports Board members in their continuous learning. The Board encourages directors to participate in continuing education programs, and we reimburse directors for their expenses associated with this participation. During Board and committee meetings, education and information sessions are provided on specific subjects by internal and external experts. New directors also participate in our director orientation program.

 

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Corporate Governance

Regular Board and Committee Evaluations

Board and committee evaluations play a critical role in supporting the effective functioning of our Board. Through evaluations, our directors review where they believe our Board functions effectively and, importantly, areas where our Board thinks there may be opportunities for improvement, including through Board refreshment.

Annual Governance Review. Our Governance Committee leads an annual evaluation process of the Board and its committees. Directors provide feedback regarding Board and committee composition and structure, role and effectiveness, fulfillment of fiduciary duties, meetings and materials, and interaction with management.

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Evaluation Results. The Audit, Compensation, Compliance, and Governance Committees each completed their assessments in October 2019 for further evaluation by the Governance Committee in December 2019. The Board completed its evaluation in December 2019. Each committee and the Board was satisfied with its performance and each was considered to be operating effectively, with appropriate balance among governance, oversight, strategic, and operational matters.

Ongoing Feedback. Our directors provide real-time feedback throughout the year outside of the formal evaluation process and have open access to management and third-party advisors. Additionally,

executive sessions of directors (without management) are scheduled for every regular Board and committee meeting to identify any issues and assess whether meeting objectives were satisfied.

Changes Implemented. Based on the annual Board and committee evaluation process, ongoing feedback provided by directors, andone-on-one discussions between our lead independent director and each director, changes to Board practices have included enhancements to our committee structure and composition, additional presentations on various topics, and the addition of new directors.

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Corporate Governance

 

 

 

 

 

Regular Board and Committee Evaluations

Board and committee evaluations play a critical role in supporting the effective functioning of our Board. Through evaluations, our directors review where they believe our Board functions effectively and,

importantly, areas where our Board thinks there may be opportunities for improvement, including through Board refreshment.

Annual Governance Review

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Planning The Governance Committee oversees the Board evaluation process. In consultation with our lead independent director, and the committee Chairs, a framework for evaluation is established, including a review of topics for evaluation that are incorporated in the evaluation forms used by the Board and committees. Committee Evaluations and Assessment Formal annual anonymous evaluations of the Audit, Compensation, Compliance, and Governance Committees are collected, compiled, and distributed in advance of the scheduled discussion by each committee in executive session (typically in October). The evaluations include open-ended questions and space for candid commentary. All comments are unattributed, included verbatim, and shared with the full Board and each applicable committee. Each committee Chair reports out to the full Board on these assessments for review and discussion. One-on-One Discussions Our lead independent director conducts one-on-one discussions with each independent director. These candid conversations allow for direct and honest feedback on varied aspects of our Board's operations. Board Evaluation and Assessment Annual anonymous evaluations of the Board are collected, compiled, and distributed in advance of the scheduled discussion by the full Board in executive session (typically in December) and informed by the results of the committee-level evaluation discussions as well as the one-on-one discussions conducted by the lead independent director. Follow-Up Policies, practices, and the composition of our Board and its committees are modified, as appropriate, based on evaluation findings, one-on-one discussions, and follow-up items are discussed at subsequent Board and committee meetings. Ongoing Our directors are encouraged to convey ongoing feedback to our lead independent director or the Governance Committee during any executive session throughout the year.

Evaluation Results. The Audit, Compensation, Compliance, and Governance Committees each completed their committee evaluations and assessments in October 2021 and such evaluations were included as part of the total evaluation by the Governance Committee in December 2021. The Board completed its evaluation in December 2021. Each committee and the Board was considered to be operating effectively, with appropriate balance among governance, oversight, strategic, and operational matters, and each committee and the Board was satisfied with its performance.

Ongoing Feedback. Our directors provide real-time feedback throughout the year outside of the formal evaluation process and have

open access to management and third-party advisors. Additionally, executive sessions of directors (without management) are scheduled for every regular Board and committee meeting to identify any issues and assess whether meeting objectives were satisfied.

Changes Implemented. Based on the annual Board and committee evaluation process, ongoing feedback provided by directors, and one-on-one discussions between our lead independent director and each independent director, changes to Board practices have included enhancements to our committee structure and composition, additional presentations on various topics, and the addition of new directors.

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Corporate Governance

Director Independence

 

 

At least annually, the Governance Committee reviews the independence of eachnon-employee director and makes recommendations to the Board and the Board affirmatively determines whether each director qualifies as independent. Each director must keep the Governance Committee fully and promptly informed as to any development that may affect the director’s independence.

The Board has determined that each of ournon-employee directors isdirectors: Wanda M. Austin; Brian J. Druker; Robert A. Eckert; Greg C. Garland; Charles M. Holley, Jr.; S. Omar Ishrak; Tyler Jacks; Ellen J. Kullman; Amy E. Miles; Ronald D. Sugar; and Frank C. Herringer, whoR. Sanders Williams; and Fred Hassan (who served as a director during part of 2019,2021) was independent during 20192021 under The NASDAQ Stock Market listing standards and the requirements of the SEC. Mr. Bradway is not independent based on his service as our CEO and President. Mr. Bradway is the only director who also serves us in a management capacity. In making its independence determinations, the Board reviewed direct and indirect transactions and relationships between each director or any member of his or her immediate family, and us or oneany of our subsidiaries or affiliates based on information provided by the director, our records, andand/or publicly available information.

All of the reviewed transactions and arrangements were entered into in the ordinary course of business and none of the business transactions, donations, or grants involved an amount that (i) exceeded the greater of 5% of the recipient entity’s revenues or $200,000 with respect to transactions where a director or any member of his or her immediate family or spouse served as an employee, officer, partner, director, or director,controlling shareholder, or (ii) exceeded $10,000 with respect to professional or consulting services provided by entities at which directors serve as professors or employees.

The following types and categories of transactions, relationships, and arrangements were considered by our Board in making its independence determinations:

 

Each of the independent directors (or their immediate family members), except for Fred Hassan, currently serves or has previously served within the last three years as a professor, trustee,

  

three years as a professor, trustee, director, or member of a board, advisory board, council, or committee for one or more colleges, universities, ornon-profit charitable organizations, including research or scientific institutions, to which Thethe Amgen Foundation Inc. has made grants or matching donations under ourthe Amgen matching gift program that is available to all of our employees and directors, or has made grants.directors.

 

Each of the independent directors (or their immediate family members) currently serves, or has previously served within the last three years, as a member of the board of directors, or the board of trustees, or an advisory board for an entity with which Amgen has business transactions or to which Amgen or the Amgen Foundation makes donations or grants. TheThese business transactions include, among other things, purchasing supplies, equipment and software licenses, payment of fees or memberships, and expenses relating to repair and maintenance, utilities, clinical trials, research and development and training, sponsorship of healthcare programs and conferences, financial advisory, investment management, investment advisory and consulting services, and reimbursement of business-related expenses incurred by our staff members (such as for transportation, gas, and food purchases).

 

Wanda M. Austin, Brian J. Druker, Rebecca M. Henderson, Tyler Jacks, and R. Sanders Williams currently serve as professors for universities to which Amgen has made payments for certain business transactions such as symposiums, conferences and exhibits, postdoctoral research programs, clinical trials, training and research and development, software licenses and maintenance, as well as for grants.grants from the Amgen Foundation.

None of the directors, directly or indirectly, provides any professional or consulting services to us and none of the directors currently has or has had any direct or indirect material interest in any of the above transactions and arrangements. The Board determined that these transactions and arrangements did not warrant a determination that the director wasany of our directors were not independent.

 

 

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Corporate Governance

 

 

 

 

 

Governance Committee Processes and Procedures for Considering and Determining Director Compensation

 

 

The Governance Committee has the authority to evaluate and make recommendations to our Board regarding director compensation.

 

The Governance Committee conducts this evaluation periodically by reviewing our director compensation practices against the practices of an appropriate peer group and the Governance Committee may determine to make recommendations to our Board regarding possible changes to director compensation. The Governance Committee conducted such an assessment in 2017 and no changes were made to director compensation. The Governance Committee has the authority to retain consultants to advise on director compensation matters, including in support of the Governance Committee’s periodic review of director compensation practices.

In 2020, the Governance Committee engaged Frederic W. Cook and Co., or FW Cook, to provide advice regarding director compensation.

  

compensation matters. During 2017, the Governance Committee engaged Frederic W. Cook and Co., or FW Cook, to provide advice regarding director compensation. FW Cook reported directly to the Governance Committee and attended the Governance Committee meeting to evaluate director compensation. No executive officer has any role in determining or recommending the form or amount of director compensation.

 

The Governance Committee has authority to delegate any of these functions to a subcommittee of its members.

Based on the analysis provided by FW Cook, the Governance Committee determined to make changes to director compensation effective for 2021, the first increase since 2013, to align with market practice and attract and retain high-quality director candidates in a competitive global marketplace. For more information regarding director compensation, see “Director Compensation—2021 Director Compensation.

 

 

 

Audit Committee

 

Current Members:

Charles M. Holley, Jr.* (Chair)

Wanda M. Austin

Fred Hassan*

Ellen J. Kullman*

Amy E. Miles*

 

*Audit Committee financial expert

 

Others Who Servedwho served in 2019:2021:

Frank C. HerringerFred Hassan (until retirement at 20192021 Annual Meeting)

Brian J. Druker

Rebecca M. Henderson

Tyler Jacks

 

Number of Meetings Held in 2019:2021: 10

 

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC, including the requirements regarding financial literacy and sophistication.

 

     

 

Description and Key Responsibilities:

 

   Oversees our accounting and financial reporting process and the audits of the financial statements, as required by NASDAQ.

 

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the oversight of our financial accounting and reporting, the underlying internal controls and procedures over financial reporting, and the audits of the financial statements.

 

   Has sole authority for the appointment, compensation, and oversight of the work of the independent registered public accountants.

 

   Reviews and discusses, prior to filing or issuance, with management and the independent registered public accountants (when appropriate) our audited consolidated financial statements to be included in our Annual Report on Form10-K and earnings press releases.

 

   Approves all related party transactions, as required by NASDAQ.transactions.

   Reviews any violations or alleged violations of the Company’s Code of Ethics for the CEO and Senior Financial Officers.

 

   

 

Audit Committee Oversight of the Independent Registered Public Accountants

•   Auditor Selection. Evaluates the qualifications and performance of our independent registered public accountants each year and appoints the independent registered public accountants annually.

•   Audit Partner Selection. Participates directly in the selection of the lead engagement partner through an interview process.

•   Audit Firm Evaluation. Considers the quality and efficiency of the services provided, the independent registered public accountants’ technical expertise and knowledge of our operations and industry.

•   Audit Services.Pre-approves services.

 

  
        

 

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Corporate Governance

 

 

 

 

 

 

Corporate Responsibility and Compliance Committee

 

Current Members:

Ronald D. Sugar (Chair)

Brian J. Druker

Rebecca M. HendersonS. Omar Ishrak (since July 30, 2021)

Tyler Jacks

R. Sanders Williams

 

Others Who Served in 2019:

Wanda M. Austin

Charles M. Holley, Jr

Number of Meetings Held in 2019:2021: 5

 

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

 

 

    

 

Description and Key Responsibilities:

 

   Oversees our compliance program and reviews our programs in a number of areas governing ethical conduct including:

 

-  U.S. federal health care program requirements;

 

-  U.S. Food and Drug Administration requirements and other regulatory agency requirements, including good manufacturing, clinical and laboratory practices, drug safety and pharmacovigilance activities;

 

-  interactions with members of the healthcare community;

 

-  the Company’s Corporate Integrity Agreement;

 

-  anti-bribery/anti-corruption activities;risks;

 

-  environment, health, and safety;

 

-  information security, including cybersecurity; and

 

-  human resourcesaspects of labor and employment activities and diversity, inclusion and belonging(1); and

-government affairs.affairs, including the Political Action Committee.

 

   Receives regular updates on pricingvalue (which includes pricing) and access, political, social, and environmental trends, and public policy issues that may affect our reputation, including our business or public image, and reviews our elements of our corporate responsibility (including environmental sustainability), political, and philanthropic activities.

 

About Our Compliance Program

 

 

Amgen’s Compliance Program is designed to promote ethical business conduct and ensure compliance with applicable laws and regulations. The key objectives of our compliance program operations include:

 

developingDeveloping policies and procedures;

 

providingProviding ongoing compliance training and education;

 

auditingAuditing and monitoring compliance risks;

 

maintainingMaintaining and promoting avenues for staff to raise concerns without fear of retaliation, including anonymously through a business conduct hotline;

conductingConducting investigations;

 

respondingResponding appropriately to any compliance violations; and

 

takingTaking appropriate steps to detect and prevent recurrence.recurrence, including by implementing appropriate corrective and preventive actions; and

Promoting an ethical culture.

Our Chief Compliance Officer, who reports to the CEO and the Compliance Committee, oversees the ongoing operations of the compliance program.

 

 

(1)

Beginning in 2022, oversight of those aspects of labor and employment activities (including diversity, inclusion and belonging), previously overseen by the Compliance Committee, moved to the Compensation Committee.

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Corporate Governance

 

 

 

 

 

Our Approach to Environmental Sustainability, Social Responsibility, and Human Capital Management

Amgen’s ESG strategy begins with our mission to serve patients and is supported by our long-standing focus on using resources responsibly to support the sustainability of our business and the global environment in which we and our patients live.

ESG Oversight and Governance

ESG at Amgen is governed at the highest levels and includes Board and committee oversight, executive-level leadership, and subject-matter experts who lead our ESG efforts across our business.

Board Oversight. The Board and its applicable committees provide guidance and oversight to management with respect to ESG matters. The Compliance Committee assists the Board in overseeing our activities in areas that include environmental sustainability, diversity, inclusion and belonging, and access to medicines. Beginning in 2022, oversight of diversity, inclusion and belonging shifted to the Compensation Committee, the committee that also provides oversight of our approach to human capital management. The Governance Committee oversees the Company’s corporate governance activities and Board membership. Additionally, management shares feedback received from our stockholders with the Board, including in connection with our governance-focused engagement program. For additional discussion, please see “Positive 2021 Say on Pay Vote Outcome and Compensation Design Changes in Response to 2021 Stockholder Input” in our Compensation Discussion and Analysis.

Management Leadership. A cross-functional, executive-level governance council sets our overall ESG strategy, provides guidance on program implementation, and oversees the continuing enhancement of our approach to ESG. This council, chaired by our Senior Vice President, Corporate Affairs, regularly evaluates current and emerging ESG-related risk topics that are relevant to our business, including those considered as part of our ERM program. For additional information, please see “The Board’s Role in Risk Oversight” previously discussed.

Our ESG framework currently includes four strategic pillars—Healthy People, Healthy Society, Healthy Planet, and A Healthy Amgen—that serve as organizing principles facilitating our ability to address the interconnectivity of issues in a more holistic way across our business.

Amgen’s ESG Framework

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Program Implementation.Each pillar is supported by an initiative steering committee and, together with the oversight of our executive leadership, individual programmatic elements are managed at a business function level. Since 2021, to further integrate ESG across the organization, our Compensation Committee added an ESG goal to our Company performance goals for our annual cash incentive plan. For additional information, please see “Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance” in our Compensation Discussion and Analysis.

In addition to our history of strong corporate governance practices, examples of our ESG initiatives include our endeavors to strengthen science education and inspire the next generation of scientists, expand access to our medicines and support efforts to strengthen healthcare systems to better serve patients in need worldwide, and pursue a more environmentally sustainable business model. For additional information, please see “Board of Directors Corporate Governance Highlights” previously discussed.

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Corporate Governance

Environmental Sustainability

As a science-based company committed to advancing human health, Amgen recognizes the importance of climate change on human health around the world. We have a long-standing objective to conduct environmentally responsible operations and regularly set targets to challenge ourselves to deliver further improvements. Since 2007, we have successfully advanced our environmental sustainability program while substantially increasing our global production capacity and patient reach.

Building on the successful execution of our 2013-2020 conservation targets, we launched a new environmental sustainability plan in 2021 (our third since 2007) that includes a target of achieving carbon neutrality in our operations by 2027, while also aiming to further reduce our water use (by 40%) and waste disposed (by 75%).(1)

LOGO

Our 2027 Environmental Sustainability Plan. To achieve our 2027 goals, we plan to harness our innovative capabilities to help combat climate change and preserve natural resources. We expect these efforts to help us become not just more environmentally sustainable but also more flexible and productive, resulting in reductions in operating costs from such efficiencies over the same period.

Our 2027 plan is designed to drive specific environmental sustainability projects across our operations, including continued investment in highly resource efficient biomanufacturing, smart and integrated facility design, use of on-site solar and other renewable energy sources, electric vehicle fleet conversion, treatment and reuse of water, the reduction and recycling of single-use plastics, and the reduction of consumables packaging. This plan also includes activities to further integrate the potential risks and opportunities from climate change into our existing processes for strategic planning, analysis, and risk management.

The Road to Net Zero. To help achieve our goal of carbon neutrality by 2027(1), Amgen is focusing on the use of innovative technologies and efficiency projects to reduce carbon emissions from our owned and operated facilities, in addition to sourcing renewable energy. Where renewable sources are not available, we expect to prioritize offsetting based on the quality of the credit or offset.

Sustainability by Design. Amgen helped to invent the processes and tools that created the global biotech industry. As we continue to grow

and innovate, we are pioneering advanced technologies and implementing more environmentally responsible approaches throughout the Company to increase operational efficiency and reduce our environmental footprint.

Our next-generation biomanufacturing facility in Singapore, which began commercial production in 2017, is an example of our innovative capability at work. This redesign of our approach to biomanufacturing dramatically reduces the scale and costs of making biologic medicines, and vastly reduces water and energy use, while maintaining a reliable, high-quality, compliant supply of medicines.

LOGO

The success of our facility in Singapore, along with U.S. corporation tax incentives to invest in innovation and advanced technologies, led to our building a second such plant in the U.S. in Rhode Island. This facility was licensed by the U.S. Food and Drug Administration in January 2022 and will support product volume growth, while delivering environmental and operating efficiencies.

We continue to apply innovation to our facilities with multiple ongoing projects, including in connection with the expansion of our U.S. plants. In 2021, we commenced construction on two new facilities (a final product assembly and packaging plant in Ohio and a multi-product drug substance facility in North Carolina). These facilities are expected to support our ability to meet the demand for our medicines, utilize cutting-edge technologies to be more efficient and environmentally friendly than traditional plants, and bring hundreds of full-time jobs to the regions while expanding our access to diverse talent.

(1)

Carbon neutrality goal refers to Scope 1 and 2. Reductions take into account only verified reduction projections, do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

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Sustainable Value Chain. Our footprint and focus on sustainability extend beyond our own employees and facilities. Amgen’s 2027 environmental sustainability plan includes engaging with our suppliers and contactors to evaluate the carbon impact throughout our value chain and identify reduction opportunities.

ESG Reporting.Informed by insights from our investors, we enhanced our ESG reporting in 2021 by expanding our latest Environmental, Social, and Governance Report by mapping our reporting to the Sustainability Accounting Standards Board (SASB) standards for our industry, disclosing our annual Consolidated EEO-1 Report, and providing additional metrics on the diversity of our workforce.

Since 2010, Amgen has reported to CDP (formally the Carbon Disclosure Project). Over time, CDP’s disclosure platform for climate change has evolved to contain over 25 questions (within its governance, risks and opportunities, strategy, targets and emissions modules) that are aligned with the recommendations of the Task Force on Climate-related Financial Disclosures, or TCFD; this platform is now nearly in full alignment with the TCFD. We continue to report to the CDP as completely as possible and, in 2022, we are undertaking a TCFD-aligned scenario analysis to improve our understanding of the physical and transitional effects of climate change as well as inform our future reporting.

United Nations Global Compact. We are a signatory to the United Nations Global Compact, a voluntary initiative based on commitments to implement universal sustainability principles and take steps to support the United Nations Sustainable Development Goals.

Social Responsibility

Improving Patient Access to Medicines. Through patient assistance programs, expanded access to investigational therapies, donations, and other initiatives, Amgen has developed support programs for eligible patients around the world as they seek to obtain the medicines they need.

Amgen Safety Net Foundation (ASNF), a separate legal entity entirely funded by Amgen, supports qualifying patients in the U.S. who might go without important medicines because of financial limitations, by providing our medicines at no cost. In 2021, the commercial value of Amgen’s medicines provided at no cost to uninsured or underinsured patients by ASNF was over $2 billion.(1)

Since 2018, Amgen has also donated approximately $140 million worth of Amgen cancer treatment and supportive care medicines(1) for distribution to patients in more than 30 developing countries through Direct Relief, a leading non-governmental organization.

We continue to offer and implement value-based contracts in an effort to help improve patient access to medicines and offer stakeholders greater budget predictability.

Advancing Health Equity. As part of our mission to serve patients, we are working to improve the diversity and representation of racial and ethnic minority populations in clinical trial research at Amgen and to advance solutions and increase dialogue regarding this area across the industry.

We recognize the importance of a patient-centric approach to clinical research and our Representation in Clinical Research (RISE) team is working with groups within Amgen and outside of the business towards exceeding industry standards for clinical trial diversity and representation and helping Amgen develop new medicines studied in participants who better reflect the populations affected by certain diseases or conditions. We also continue building relationships with leaders and organizations in diverse communities to help address healthcare disparities, improve disease state awareness, and increase dialogue in this area.

Supplier Diversity and Responsible Sourcing. We aspire to double our supplier diversity spend, and triple our Black-owned business spend, in the U.S. by 2023.(2) Our supplier diversity program is designed to identify, develop, and utilize small, disadvantaged, veteran, LGBTQ, minority, disabled, and women-owned business enterprises, as well as companies located in historically underutilized business zones, in our procurement of goods and services. Our efforts include mentoring and development opportunities to further strengthen the leadership capabilities of these diverse suppliers and contactors.

All staff members are guided by the Amgen Values and global Code of Conduct and, similarly, we request our suppliers to conduct their businesses in alignment with our mission and values. Our supplier sustainability program focuses not only on quality, cost, and reliability but also on a wide range of sustainability and social responsibility considerations, such as business ethics, labor and human rights, and environmental impacts.

Science Education. The Amgen Foundation seeks to advance excellence in science education to inspire the next generation of innovators and invest in strengthening communities where our staff members live and work.

Since its inception over 30 years ago, the Amgen Foundation has contributed more than $375 million to non-profit organizations around the world that reflect our core values and complement Amgen’s dedication to impacting lives in inspiring and innovative ways.

LabXchange, developed at Harvard University with the financial support of the Amgen Foundation, is a free online science education platform that provides students around the world with access to personalized instruction, virtual lab experiences, and networking opportunities across the global scientific community. In 2021, with the Amgen Foundation’s support, LabXchange launched a digital curriculum focused on examining racial inequity in healthcare, education, and STEM fields in the U.S.

The Amgen Foundation is the exclusive biology content partner of Khan Academy, a leading online learning platform, and approximately

(1)

Valued at wholesale acquisition cost.

(2)

Measured against a 2019 baseline.

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Corporate Governance

15 million users accessed Khan Academy’s free biology lessons in 2021. Through an expanded, multi-year partnership with the Amgen Foundation in support of science learning and education equity, Khan Academy is creating a comprehensive offering of biology resources for students and teachers worldwide and expanding its partnerships with school districts facing budget shortfalls.

Additionally, the Amgen Foundation continued to expand the Amgen Biotech Experience (ABE), an innovative science education program that empowers high school teachers to bring biotechnology education into their classrooms. In 2021, the second cohort of the ABE Master Teacher Fellowship was announced with twelve fellows from around the globe who each receive a stipend and targeted support to develop a curriculum project to be shared with the ABE international community.

The Amgen Scholars Program makes it possible for undergraduates around the globe to engage in cutting-edge research experiences in leading graduate laboratories and learn more about biotechnology and drug discovery.

Our Community. In 2021, The Amgen Foundation provided grants totaling $3 million to more than 30 U.S.-based nonprofits in support of racial and social justice initiatives, economic empowerment, and equal opportunity in education.

Amgen and the Amgen Foundation have been engaged with our community during the pandemic. For additional information, please see “Responding to COVID-19” previously discussed.

The Amgen Foundation also provides programs and resources to empower individual Amgen staff in their charitable activities in our community, including through a matching gift program and by providing service grants to non-profit organizations where staff members regularly volunteer.

Human Capital Management

Our Board has a key role in the oversight of our culture, setting the tone at the top, and holding management accountable for maintaining high ethical standards. The Board believes that human capital management, including our diversity, inclusion, and belonging initiatives, are important to our success. The Compensation Committee assists the Board in providing oversight of human capital management and, beginning in 2022, labor and employment and diversity, inclusion, and belonging oversight responsibilities, previously overseen by the Compliance Committee, moved to the Compensation Committee. We conduct regular staff member engagement assessments that gather feedback on topics, including on the overall engagement of staff members, diversity, inclusion, and belonging, and our culture of compliance, and the results of these surveys are discussed with our workforce and the Board.

Amgen places significant value on fostering and enabling growth of staff, both personally and professionally, and we aim to provide a safe, healthy, innovative, and diverse work environment for our staff.

Our Social Architecture. Since Amgen’s founding in 1980, our staff members have directed their intelligence and enthusiasm toward our mission to serve patients. The combination of our mission, our aspiration to be the world’s best human therapeutics company, our strategy, our well-defined set of Amgen Values, and the clear leadership attributes that we expect from our staff members, form the “social architecture” that defines our unique culture. This social architecture has been a key enabler of Amgen’s worldwide growth from an early pioneer in the biotech industry to a leading innovator.

The Amgen Values were formalized in 1996 and continue to serve as the principles that guide the way we conduct business.

Amgen Values

Be Science-Based

Trust and Respect

Each Other

Compete Intensely

and Win

Ensure Quality

Create Value for

Patients,

Staff, and

Stockholders

Work in Teams
Be Ethical

Collaborate,

Communicate, and Be

Accountable

Diverse and Inclusive Workforce. Consistent with the Amgen Values, we are working to bring the diversity of the world community into the Amgen community. We believe that a diverse and inclusive culture fosters innovation, which supports our ability to serve patients. Further, we also believe our global presence is strengthened by having a workforce that reflects the diversity of the patients we serve. It is with these beliefs in mind that we have continued to strengthen and grow our culture of diversity, inclusion, and belonging.

Our Diversity, Inclusion and Belonging Council is led by our executive leadership and is responsible for overseeing our strategy to further a diverse and inclusive workplace, with an ongoing focus on women in leadership and minority representation. With endorsement from executive management and engagement with senior leaders across the organization, we are implementing a global strategy designed to leverage our diversity and create a more inclusive workplace.

We are engaging in activities and setting goals to improve our focus around diversity, inclusion, and belonging, including the launch of a mandatory unconscious bias training program that was completed by 100% of our U.S., Canada, and Puerto Rico staff members in 2020 (with a global rollout in 2021) and an online learning journey with tools and resources that guides staff members on the role they play in advancing diversity, inclusion and belonging throughout the organization.

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Each of our eleven Employee Resource Groups, dedicated to representing, supporting, and celebrating the diversity of our staff, are supported by a sponsor from our senior executive leadership team.

Amgen Employee Resource Groups

Amgen Asian
Association (AAA)

Amgen Black
Employee Network
(ABEN)

Ability Bettered through Leadership and
Education (ABLE), a resource group for those with
disabilities, visible and invisible

Amgen Early Career
Professionals (AECP)

Amgen International
Network (AIN)

Amgen Indian
Subcontinent
Network (AISN)

Amgen Latin Employee
Network (ALEN)

Amgen LGBTQ and
Allies Network
(PRIDE)

Amgen Veterans
Employees Network
(AVEN)

Women Empowered
to be Exceptional
(WE2)

Women in Information
Systems Enrichment

(WISE)

Amgen is a founding member of OneTen, a coalition of many of the world’s largest, best-known companies that aims collectively to hire one million Black Americans (with a specific focus on those without four-year college degrees) into good-paying family-sustaining jobs over the next ten years.

Amgen is taking a leadership role in the greater Los Angeles region, where we are headquartered, to help expand the coalition of organizations that share our desire to offer opportunities to diverse talent.

Attracting and Developing Talent. We recognize the importance of attracting, motivating, developing, and retaining top global talent and skilled staff members. We compensate our staff members based on their roles, experience, and performance, provide wellness and work-life resources, as well as support employees in giving back and volunteering in their local communities. To support the development of our staff, we provide a variety of programs, including leadership development programs, virtual instructor-led courses, and self-paced learning options.

Our benefit programs are generally broad-based, promote health and overall well-being, and emphasize saving for retirement. Amgen continues to pride itself on industry-leading, family-friendly offerings for families of all compositions, including, in the U.S. and Puerto Rico, on-site child care at certain of our facilities, adoption assistance, resources for elder care and behavioral health, and paid parental leave for all Amgen staff members who have or adopt, or become a foster parent or legal guardian for a child. Globally, comparable benefit programs are offered with the same health and well-being goals, while also designed to comply with local statutory requirements.

(For more information regarding our approach to human capital resource management, including activities in support of workplace safety and diversity, please see our Form 10-K for the year ended December 31, 2021.)

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Corporate Governance

 

Compensation and Management Development Committee

 

Current Members:

Robert A. Eckert (Chair)

Wanda M. Austin (since August 2019)

Brian J. Druker (since August 2019)

Greg C. Garland

Fred HassanS. Omar Ishrak (since July 30, 2021)

Tyler Jacks

Others who served during 2021:

Fred Hassan (until retirement at 2021 Annual Meeting)

 

Number of Meetings Held in 2019:2021: 6

 

Independent Compensation

Consultant:FW Cook

 

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

     

 

Description and Key Responsibilities:

 

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the oversight of the Company’s compensation plans, policies, and programs with a focus on encouraging high performance, promoting accountability and adherence to Company values, and aligning with the interests of the Company’s stockholders.

 

   Approves all executive officer compensation.

 

   Oversees human capital management and succession planning for senior management, including that our approaches to management development are effective in attracting, developing, and retaining talented leadership. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities previously overseen by the Compliance Committee, moved to the Compensation Committee.

 

   Oversees the Board’s relationship with stockholders on executive compensation matters, including stockholder outreach efforts, stockholder proposals, advisory votes, communications with proxy advisory firms, and related matters.

 

 

 

Executive Compensation Website

We maintain a website accessible throughout the year atwww.amgen.com/executive compensation(1), which provides a link to our most recent proxy statement and invites our stockholders to fill out a survey to provide input and feedback to the Compensation Committee regarding our executive compensation policies and practices.

 

 
  
 

 

Equity Award Committee

The Equity Award Committee, 4Meetings Held

Determineswith Robert A. Bradway currently the sole member, assists the Board by determining equity-based awards tonon-Section 16 officers and employees at the level of vice presidents andpresident or below, consistent with the equity grant guidelines established by the Compensation Committee.

Current Member:

Robert A. Bradway

Others Who ServedCommittee, and acted five times in 2019:

Robert A. Eckert, Greg C. Garland2021.

 

       

Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 20192021

 

 

Compensation Committee Determination of Compensation.ByGenerally, by the first calendar quarter of each year, the Compensation Committee reviews and approves Company performance goals and objectives for the current year and evaluates the CEO’s performance for the previous year in light of the Company performance goals and objectives established for the prior year. The Compensation Committee evaluates the performance of the CEO within the context of the financial and operational performance of the Company, considers competitive market data, and establishes the CEO’s compensation based on this evaluation as well as the compensation for each executive officer.

Values and Components.The values of each component of total compensation (base salary, target annual cash incentive awards, and equity awards) for the current year, as well as total annual compensation for the prior year (including the value of equity holdings, potential change of control payments, and vested benefits under our Retirement and Savings Plan, Supplemental Retirement Plan, and Nonqualified Deferred Compensation Plan as of the end of the last fiscal year) are considered at this time. Final determinations regarding our

CEO’s performance and compensation are made during an executive

session of the Compensation Committee and are reported to and reviewed by the Board in an independent directors’ session.

Executive Officers. Our Compensation Committee determines compensation for the executive officers (other than the CEO) based, in part, on the recommendations of our CEO regarding base salary, annual cash incentive awards, and equity awards. In determining compensation recommendations for each Named Executive Officer, or NEO, our CEO reviews comparative peer group data, as well as the performance of the executive. The Compensation Committee has typically followed these recommendations.

Executive Sessions.Each Compensation Committee meeting includes adequate time for executive session and the Compensation Committee meets in executive session on a regular basis with no members of management present (unless otherwise requested by the Compensation Committee).

Delegation of Authority. The Compensation Committee has authority to delegate any of its functions to a subcommittee of its members.

 

 

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

2836    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Corporate Governance

 

 

 

 

 

Delegation of Authority. The Compensation Committee has authority to delegate any of its functions to a subcommittee of its members. No delegation of authority was made in 2021.

Independent Compensation Consultant. The Compensation Committee continued to engage FW Cook, an independent compensation consultant, to provide advice regarding executive compensation and executive compensation trends and developments, compensation designs, and equity compensation practices, market data as requested, and opinions on the appropriateness and competitiveness of our executive compensation programs relative to market practice. FW Cook reported directly to the Compensation Committee and attended regularly scheduled meetings of the Compensation Committee (including meeting in executive session with the Compensation Committee, as requested). Each year the Compensation Committee reviews the independence of FW Cook and whether any conflicts of interest exist.

After review and consultation with FW Cook, the Compensation Committee has determined that FW Cook is independent and there is no conflict of interest resulting from retaining FW Cook currently or during the year ended December 31, 2019.2021. In performing its analysis, the Compensation Committee

considers the factors set forth in the SEC rules and The NASDAQ Stock Market listing standards.

Peer Group Review. In setting executive compensation, the Compensation Committee compares the Company’s pay levels and programs to those ofavailable for the Company’s competitors for executive talent and uses this comparative data as a guide in its review and determination of compensation. Our Compensation Committee annually considers and selects an appropriate peer group (consisting of biotechnology and pharmaceutical companies), based, in part, on the recommendations of FW Cook, and, for each Named Executive Officer, or NEO, the Compensation Committee reviews the compensation levels and practices of our peer group, which for our NEOs, other than the CEO, are based on reports prepared by management from information contained in compensation surveys and proxy statements. FW Cook provides the Compensation Committee with market data, an annual report on the compensation levels and practices of our peer group, and compensation recommendations for the CEO position.

Compensation Risk Management.In cooperation with management, FW Cook assesses the potential risks arising from our compensation policies and practices as discussed more fully below.

 

 

Compensation Risk Management

 

 

Annual Risk Management Assessment.On an annual basis, management, working with the Compensation Committee’s independent compensation consultant, conducts an assessment of the Company’s compensation policies and practices for all staff members generally, and for our staff members who participate in our sales incentive compensation program, for material risk to the Company. Compensation-related risks from COVID-19 were evaluated as part of this assessment for 2021.

Results of Risk Management Assessment.The results of this assessment are reviewed and discussed with the Compensation Committee. Based on this assessment, review and discussion, we believe that, through a combination of risk-mitigating features and incentives guided by relevant market practices and our Company performance goals, our compensation policies and practices do not present risks that are reasonably likely to have a material adverse effect on us.

Factors That Discourage Excessive Risk-Taking.In evaluating our compensation policies and practices, a number of factors were identified which the Company, the Compensation Committee, and its independent consultant believe discourage excessive risk-taking, including:

 

 

Mix of Incentives.Incentives and Metrics. Our compensation programs consist of a mix of incentives and metrics (financial and operational) that are tied to varying performance periods and are designed to balance our need to drive our current performance with the need to position the Company for long-term success.

 

 

Company-wide Results.Company-wide.Company-wide results are the most

important factor in determining the amount of an annual cash incentive award, one of our mix of incentives, for each of our staff members.

 

 

Emphasis on Long-Term Performance. We cap short-term incentives and make long-term incentive, or LTI equity awards a component of compensation for nearly all of our full-time staff members. In particular, the CEO and the other executive officers

participate in compensation plans that are designed so that the largest component of their compensation is in the form of LTI equity awards to ensure that a significant portion of their compensation is associated with long-term, rather than short-term, outcomes, which aligns these individuals’ interests with those of our stockholders.

 

 

Equity Award Grant Practices.We employ appropriate practices with respect to equity awards: we do not award mega-grants, discounted stock options, or immediately vested equity to staff members; and we have grant guidelines that generally limit the grant date for our equity grants to the third business day after our announcement of quarterly earnings.

 

 

Robust Stock Ownership and Retention Guidelines.We have robust stock ownership guidelines for vice presidents and above that require significant investment by these individuals in our Common Stock. We require that each officer who has not met his or her required ownership guidelines hold shares of our Common Stock acquired through the vesting of restricted stock units, the payout of performance units, and the exercise of stock options (net of shares retained by us to satisfy associated tax withholding requirements and exercise price amounts) until such officer has reached his or her required stock ownership level.

 

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Corporate Governance

 

Comprehensive Performance Evaluations. Our Company values and leadership behaviors are an integral part of the performance assessments of our staff members and are particularly emphasized in our assessment tools at higher positions. These evaluations serve as an important information tool and basis for compensation decisions.

 

 

DiscretionClawback Policy. We have a clawback policy that requires our Board to Reduce Awards.The Compensation Committee retains full discretion to reduceconsider recapturing past cash or eliminate annual cash incentive awardsequity compensation payouts awarded to our executive officers if it is subsequently determined that the amounts of such compensation were determined based on financial results that are later restated and can and has modified awards downwards.the executive officer’s misconduct caused or partially caused such restatement.

 

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Corporate Governance

 

Recoupment Provisions.Recoupment. We have recoupment provisions that expressly allow the Compensation Committee or management, as appropriate, to consider employee misconduct that caused serious financial or reputational damage to the Company when determining whether an employee has earned an annual cash incentive award or the amount of any such award.

The Compensation Committee has adopted an executive officer equity recoupment policy that provides the Compensation Committee with the ability to cause the forfeiture and cancellation of unvested equity awards and any unexercised portion of any stock options (granted after December 31, 2020) if an executive officer is terminated for engaging in misconduct that caused serious financial or reputational damage to the Company (including, but not limited to, a financial restatement).

Clawback Policy. We have a clawback policy that requires our Board to consider recapturing past cash or equity compensation payouts awarded to our executive officers if it is subsequently determined that the amounts of such compensation were determined based on financial results that are later restated and

the executive officer’s misconduct caused or partially caused such restatement.

 

Disclosure. Subject to our recoupment and clawback policy statement,policies and provisions, we intend to disclose the general circumstances of any application of our recoupment provisions or clawback policypolicies and provisions against any executive officer (current or former) and the aggregate amount of compensation recovered. Our policy statement is available on our website atwww.amgen.com.

 

 

No Hedging or Pledging. Our Insider Trading Policy prohibits pledging or purchasing of our Common Stock on margin(1) and hedging the economic risk of our Common Stock (as discussed more fully below).

Mandatory Global Code of Conduct Compliance Training. We require training on our global Code of Conduct and other policies that educate our staff members on appropriate behaviors and the consequences of taking inappropriate actions.

Pricing Policies and Controls. Amgen’s drug pricing governance framework is designed to help ensure that our pricing actions around the globe are legally compliant, financially sound, and aligned with our values and corporate objectives. Our approach to pricing includes training, standard operating procedures, policies, approval mechanisms for price increases and price policy exceptions, and other controls that balance regional and country autonomy with centrally managed price discipline. Our Board, with the assistance of the Compliance Committee, has a key role in the oversight of pricing risk and regularly receives presentations from management on drug pricing practices and trends.

 

 

Prohibition on Hedging

 

 

Under our global Insider Trading Policy, all of our Board members and staff members, including our NEOs, consultants, contract workers, secondees, and temporary staff worldwide are considered “Covered Persons.” It is against the Insider Trading Policy for Covered Persons to directly or indirectly participate in transactions involving trading activities in our securities that, by their nature, are aggressive or speculative, or may give rise to an appearance of impropriety. Covered Persons may not:

 

Engage in short sales (sales of stock that the seller does not own or a sale that is completed by delivery of borrowed stock) with respect to our securities;

 

Engage in transactions that hedge or offset, or are designed to hedge or offset, any decrease in the market value of Amgen stock;

 

Purchase or pledge Amgen stock on margin or as collateral to secure a loan or other obligation(1); or

 

Enter into any derivative or similar transactions with respect to our securities.

Examples of prohibited derivative transactions include, but are not limited to, purchases or sales of puts and calls (whether written or purchased or sold), options (whether “covered” or not), forward contracts, including but not limited to prepaid variable forward contracts; put and call “collars” (“European” or “American”), “equity” or “performance” swap or exchange agreements, or any similar agreements or arrangements however denominated, in our securities.

 

 

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

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Corporate Governance

Pay Ratio

 

 

Following is a reasonable estimate, prepared under applicable SEC rules, of the ratio of the annual total compensation of our CEO to the median of the annual total compensation of our other staff members, calculated in accordance with the requirements of Item 402(c)(2)(x) of RegulationS-K. The Company determined our median employee based on total direct compensation paid to all of our staff members worldwide and recorded in our global human resources systems as of December 31, 2019.2021. Total direct compensation included base salary, (wages recorded in our payroll records as of December 31, 2019), annual cash incentive awards earned for the period (and target sales incentive awards for our sales force), and the annual grant value of LTI equity awards during 2019.2021. Earnings of our staff members outside of the U.S. were

converted to U.S. dollars using the currency exchange rate rates

as of December 31, 2019.2021. Nocost-of-living adjustments were made. We then determined the annual total compensation of our median employee for 20192021 which was $130,904.$130,589. As disclosed in the “Summary Compensation Table” appearing on page 66,73, our CEO’s annual total compensation for 20192021 was $19,612,793.$21,721,154. Based on the foregoing, the ratio of the annual total compensation of our CEO to that of the median staff member was 150166 to 1. For information on the determination of executive compensation, please see “Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 2019”2021” above and our Compensation Discussion and Analysis beginning on page 38.41.

 

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

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Corporate Governance

 

Compensation Committee Report

 

 

The Compensation Committee has reviewed and discussed the Compensation Discussion and Analysis with management, and based on the review and discussions, recommended to the Board of Directors that the Compensation Discussion and Analysis be included in the

Company’s 20202022 Annual Meeting proxy statement and incorporated by reference into the Company’s Annual Report on Form10-K for the year ended December 31, 2019.2021.

 

 

Compensation Committee of the Board of Directors

Robert A. Eckert, Chairman

Wanda M. Austin

Brian J. Druker

Greg C. Garland

Fred Hassan

Tyler Jacks

Our Commitment to Environmental Sustainability, Social Responsibility, and Human Capital Management

Corporate responsibility isOur Board has a key role in the oversight of our culture, setting the tone at the top, and holding management accountable for maintaining high ethical standards. The Board believes that human capital management, including our diversity, inclusion, and belonging initiatives, are important to our success. The Compensation Committee assists the Board in providing oversight of human capital management and, beginning in 2022, labor and employment and diversity, inclusion, and belonging oversight responsibilities, previously overseen by the Compliance Committee, moved to the Compensation Committee. We conduct regular staff member engagement assessments that gather feedback on topics, including on the overall engagement of staff members, diversity, inclusion, and belonging, and our culture of compliance, and the results of these surveys are discussed with our workforce and the Board.

Amgen since makingplaces significant value on fostering and enabling growth of staff, both personally and professionally, and we aim to provide a positive differencesafe, healthy, innovative, and diverse work environment for our staff.

Our Social Architecture. Since Amgen’s founding in the world is at the heart of what we do. As part of1980, our staff members have directed their intelligence and enthusiasm toward our mission to serve patients, we take our responsibilities seriously with respect to the areas of environmental sustainability, social responsibility and corporate governance (ESG).

ESG matters at Amgen are governed at the highest levels. Our executive leadership reports our progress to the Compliance Committee of the Board. An executive-level governance council, chaired by the Senior Vice President of Corporate Affairs, oversees the continuing evolution and enhancementpatients. The combination of our approachmission, our aspiration to corporate responsibilitybe the world’s best human therapeutics company, our strategy, our well-defined set of Amgen Values, and ESG. With the oversightclear leadership attributes that we expect from our staff members, form the “social architecture” that defines our unique culture. This social architecture has been a key enabler of executive leadership, individual programmatic elements are managed at a functional level.

In additionAmgen’s worldwide growth from an early pioneer in the biotech industry to a commitmentleading innovator.

The Amgen Values were formalized in 1996 and continue to ethical business practices, our ESG efforts include integrating environmentally sustainable practices throughout our business, improving patient access to medicines, promoting supplier sustainability and diversity, supporting science education forserve as the next generation of innovators, and enhancingprinciples that guide the diversity and inclusiveness of our workplace.

Environmental Sustainabilityway we conduct business.

We have a long-standing commitment to reducing our impact on the environment and regularly set targets to challenge ourselves to deliver further improvements.Amgen Values

 

Be Science-Based

 

LOGO

Trust and Respect

Each Other

Compete Intensely

and Win

Ensure Quality

Create Value for

Patients,

Staff, and

Stockholders

Work in Teams
Be Ethical

Collaborate,

Communicate, and Be

Accountable

Progress Toward Targets.Diverse and Inclusive Workforce. Consistent with the Amgen Values, we are working to bring the diversity of the world community into the Amgen community. We believe that a diverse and inclusive culture fosters innovation, which supports our ability to serve patients. Further, we also believe our global presence is strengthened by having a workforce that reflects the diversity of the patients we serve. It is with these beliefs in mind that we have continued to strengthen and grow our culture of diversity, inclusion, and belonging.

Our Diversity, Inclusion and Belonging Council is led by our executive leadership and is responsible for overseeing our strategy to further a diverse and inclusive workplace, with an ongoing focus on women in leadership and minority representation. With endorsement from executive management and engagement with senior leaders across the organization, we are implementing a global strategy designed to leverage our diversity and create a more inclusive workplace.

We are engaging in activities and setting goals to improve our focus around diversity, inclusion, and belonging, including the last yearlaunch of a mandatory unconscious bias training program that was completed by 100% of our 2012-2020 conservation targets, which are setU.S., Canada, and Puerto Rico staff members in areas where we can make2020 (with a global rollout in 2021) and an online learning journey with tools and resources that guides staff members on the most progressrole they play in reducing our environmental impactadvancing diversity, inclusion and deliver value, including targets for reductions in fleet and facilities carbon, waste, and water use. In addition to beingon-track to deliver on all of our targets, we are well-head of our targets to reduce our carbon and water consumption.belonging throughout the organization.

 

 

34    LOGO  ï 2020 Proxy Statement    31


Corporate Governance

Reducing Carbon Emissions Through Energy Conservation. Our carbon reduction strategy focuses on eliminating energy use, increasing energy efficiency, and increasing the proportion of energy used from renewable and alternative sources. We have exceeded our 2020 carbon targets and are continuing to work through our portfolio of identified carbon reduction opportunities as we finalize our next generation of environmental targets. Amgen also participates in the CDP (formerly Carbon Disclosure Project).

Sustainable by Design. Amgen helped invent the processes and tools that created the global biotech industry. As we continue to grow and innovate, we are pioneering advanced technologies for research and development and manufacturing to increase operational efficiency, improve access to our medicines, and reduce our environmental footprint.

Our next-generation biomanufacturing facility in Singapore is an example of our innovative capability at work. This redesign of our approach to biomanufacturing dramatically reduces the scale and costs of making biologics, vastly reduces water and energy use, while maintaining a reliable, high-quality, compliant supply of medicines. In 2019, we continued to work on the construction of our second next-generation biomanufacturing plant in Rhode Island. This new plant is expected to be the first of its kind in the U.S. and will use our next-generation biomanufacturing capabilities.

United Nations Global Compact.We are a signatory to the United Nations Global Compact, a voluntary initiative based on commitments to implement universal sustainability principles and take steps to support United Nations goals.

Climate-Related Risks and Opportunities.We have processes to evaluate and quantify risk from climatic events to our operations and take steps to avoid the associated consequences. Additionally, Amgen has had a carbon and energy reduction strategy since 2008 and, as described above, considerable progress has been made in reducing our carbon footprint as a result.

Social Responsibility

Improving Patient Access to Medicines. Amgen is committed to assisting patients with no or limited drug coverage to access the medicines they need. We provide patient support and education programs and help patients in financial need access our medicines. Amgen Safety Net Foundation (ASNF), a separate legal entity entirely funded by Amgen, supports qualifying patients in the U.S. who might go without important medicines because of financial barriers, by providing our medicines at no cost. In 2019, the commercial value of Amgen’s medicines provided at no cost to uninsured or underinsured patients by ASNF was approximately $1.5 billion(1). In 2018, Amgen donated over $93 million worth of Amgen cancer treatment and supportive care medicines(1)for distribution to patients in 18 developing countries through Direct Relief, a leadingnon-governmental organization, and we recently completed a second donation of medicine through Direct Relief in 2019.

We also partner with payers to share risk and accountability for health outcomes, and help patients access the medicines they need without significant financial burden. We continue to spearhead implementation of innovative contracting, including outcomes-based and risk-sharing approaches, to improve patient access to medicines while providing budget predictability to payers, in addition to value based partnerships designed to create mutually beneficial opportunities, improve patient outcomes, experience, and satisfaction in the context of the healthcare system and overall total costs to society.

Supplier Sustainability and Diversity.All staff members are responsible for upholding the Amgen Values and Code of Conduct and, similarly, we require our suppliers to conduct their businesses in alignment with our mission and values. We focus not only on commitment to quality, cost, and reliability but also on a wide range of sustainability and social responsibility considerations, such as business ethics, labor and human rights, and environmental impacts.

We also have a supplier diversity program designed to identify, develop, and utilize small, disadvantaged, veteran, service-disabled veteran, minority, and women-owned business enterprises, as well as companies located in historically underutilized business zones, in our procurement of goods and services.

Science Education.The Amgen Foundation, Inc. (Amgen Foundation),a separate legal entity entirely funded by Amgen, seeks to advance excellence in science education to inspire the next generation of innovators, and invest in strengthening communities where our staff members live and work.

Since its inception almost 30 years ago, the Amgen Foundation has contributed more than $325 million tonon-profit organizations across the world that reflect our core values and complement Amgen’s dedication to impacting lives in inspiring and innovative ways.

Through what is now a sixteen-year commitment from the Amgen Foundation, the Amgen Scholars Program makes it possible for young scientists across the globe to engage in cutting-edge research experiences and learn more about biotechnology and drug discovery.

LabXchange, developed at Harvard University with the financial sponsorship of the Amgen Foundation, is a free online science education platform which launched in January 2020 providing students around the world with access to personalized instruction, next-generation virtual lab experiences, and networking opportunities across the global, scientific community.

The Amgen Foundation is the biology partner of the Khan Academy, a leading online learning educational platform with over 89 million registered users across the globe.

Additionally, the Amgen Foundation supports the Amgen Biotech Experience, an innovative science education program that empowers high school teachers to bring biotechnology education into their classrooms.

(1)

Valued at wholesale acquisition cost.

32    LOGOï 20202022 Proxy Statement


    

 

 

 

 

Corporate Governance

 

 

 

 

 

Our Community.The Each of our eleven Employee Resource Groups, dedicated to representing, supporting, and celebrating the diversity of our staff, are supported by a sponsor from our senior executive leadership team.

Amgen Foundation has provided support following devastating disasters, including immediate relief for victims of the wildfires in Australia and Southern California, and continues to provide support for reconstruction efforts in Puerto Rico following Hurricane Maria. Moreover, the Amgen Foundation provides programs and resources to empower individual Amgen staff in their charitable giving, including through a matching gift program and by providing service grants tonon-profitEmployee Resource Groups organizations where staff members regularly volunteer.

 

Amgen Asian
Association (AAA)

Amgen Black
Employee Network
(ABEN)

Ability Bettered through Leadership and
Education (ABLE), a resource group for those with
disabilities, visible and invisible

Amgen Early Career
Professionals (AECP)

Amgen International
Network (AIN)

Amgen Indian
Subcontinent
Network (AISN)

Amgen Latin Employee
Network (ALEN)

Amgen LGBTQ and
Allies Network
(PRIDE)

Amgen Veterans
Employees Network
(AVEN)

Women Empowered
to be Exceptional
(WE2)

Women in Information
Systems Enrichment

(WISE)

Amgen is a founding member of OneTen, a coalition of many of the world’s largest, best-known companies that aims collectively to hire one million Black Americans (with a specific focus on those without four-year college degrees) into good-paying family-sustaining jobs over the next ten years.

Amgen is taking a leadership role in the greater Los Angeles region, where we are headquartered, to help expand the coalition of organizations that share our desire to offer opportunities to diverse talent.

Attracting and Developing Talent. We recognize the importance of attracting, motivating, developing, and retaining top global talent and skilled staff members. We compensate our staff members based on their roles, experience, and performance, provide wellness and work-life resources, as well as support employees in giving back and volunteering in their local communities. To support the development of our staff, we provide a variety of programs, including leadership development programs, virtual instructor-led courses, and self-paced learning options.

Our benefit programs are generally broad-based, promote health and overall well-being, and emphasize saving for retirement. Amgen continues to pride itself on industry-leading, family-friendly offerings for families of all compositions, including, in the U.S. and Puerto Rico, on-site child care at certain of our facilities, adoption assistance, resources for elder care and behavioral health, and paid parental leave for all Amgen staff members who have or adopt, or become a foster parent or legal guardian for a child. Globally, comparable benefit programs are offered with the same health and well-being goals, while also designed to comply with local statutory requirements.

(For more information regarding our approach to human capital resource management, including activities in support of workplace safety and diversity, please see our Form 10-K for the year ended December 31, 2021.)

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Corporate Governance

 

Amgen’s ResponseCompensation and Management Development Committee

Current Members:

Robert A. Eckert (Chair)

Wanda M. Austin

Brian J. Druker

Greg C. Garland

S. Omar Ishrak (since July 30, 2021)

Tyler Jacks

Others who served during 2021:

Fred Hassan (until retirement at 2021 Annual Meeting)

Number of Meetings Held in 2021: 6

Independent Compensation Consultant: FW Cook

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

  Description and Key Responsibilities:

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the COVID-19 Pandemicoversight of the Company’s compensation plans, policies, and programs with a focus on encouraging high performance, promoting accountability and adherence to Company values, and aligning with the interests of the Company’s stockholders.

 

As   Approves all executive officer compensation.

   Oversees human capital management and succession planning for senior management, including that our approaches to management development are effective in attracting, developing, and retaining talented leadership. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities previously overseen by the Compliance Committee, moved to the Compensation Committee.

   Oversees the Board’s relationship with stockholders on executive compensation matters, including stockholder outreach efforts, stockholder proposals, advisory votes, communications with proxy advisory firms, and related matters.

Executive Compensation Website

We maintain a leading global healthcare companywebsite accessible throughout the year at www.amgen.com/executive compensation(1), which provides a link to our most recent proxy statement and responsible corporate citizen, Amgeninvites our stockholders to fill out a survey to provide input and feedback to the Compensation Committee regarding our executive compensation policies and practices.

Equity Award Committee

The Equity Award Committee, with Robert A. Bradway currently the sole member, assists the Board by determining equity-based awards to non-Section 16 officers and employees at the level of vice president or below, consistent with the equity grant guidelines established by the Compensation Committee, and acted five times in 2021.

Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 2021

Compensation Committee Determination of Compensation. Generally, by the first calendar quarter of each year, the Compensation Committee reviews and approves Company performance goals and objectives for the current year and evaluates the CEO’s performance for the previous year in light of the Company performance goals and objectives established for the prior year. The Compensation Committee evaluates the performance of the CEO within the context of the financial and operational performance of the Company, considers competitive market data, and establishes the CEO’s compensation based on this evaluation as well as the compensation for each executive officer.

Values and Components. The values of each component of total compensation (base salary, target annual cash incentive awards, and equity awards) for the current year, as well as total annual compensation for the prior year (including the value of equity holdings, potential change of control payments, and vested benefits under our Retirement and Savings Plan, Supplemental Retirement Plan, and Nonqualified Deferred Compensation Plan as of the end of the last fiscal year) are considered at this time. Final determinations regarding our

CEO’s performance and compensation are made during an executive session of the Compensation Committee and are reported to and reviewed by the Board in an independent directors’ session.

Executive Officers. Our Compensation Committee determines compensation for the executive officers (other than the CEO) based, in part, on the recommendations of our CEO regarding base salary, annual cash incentive awards, and equity awards. In determining compensation recommendations for each Named Executive Officer, or NEO, our CEO reviews comparative peer group data, as well as the performance of the executive. The Compensation Committee has typically followed these recommendations.

Executive Sessions.Each Compensation Committee meeting includes adequate time for executive session and the Compensation Committee meets in executive session on a regular basis with no members of management present (unless otherwise requested by the Compensation Committee).

(1)

Reference to our website is committednot intended to help addressfunction as a hyperlink and theCOVID-19 outbreak. We have prioritized the safety of our employees, supply of our medicines to patients, and health of the communities where we live and work. For information contained on our responsewebsite is not intended to be part of this unprecedented situation, please visitproxy statement.

36    LOGO ï 2022 Proxy Statement


www.amgen.com/COVID-19Corporate Governance(1).

 

Delegation of Authority. The Compensation Committee has authority to delegate any of its functions to a subcommittee of its members. No delegation of authority was made in 2021.

Independent Compensation Consultant. The Compensation Committee continued to engage FW Cook, an independent compensation consultant, to provide advice regarding executive compensation and executive compensation trends and developments, compensation designs, and equity compensation practices, market data as requested, and opinions on the appropriateness and competitiveness of our executive compensation programs relative to market practice. FW Cook reported directly to the Compensation Committee and attended regularly scheduled meetings of the Compensation Committee (including meeting in executive session with the Compensation Committee, as requested). Each year the Compensation Committee reviews the independence of FW Cook and whether any conflicts of interest exist. After review and consultation with FW Cook, the Compensation Committee has determined that FW Cook is independent and there is no conflict of interest resulting from retaining FW Cook currently or during the year ended December 31, 2021. In performing its analysis, the Compensation Committee

considers the factors set forth in the SEC rules and The NASDAQ Stock Market listing standards.

Peer Group Review. In setting executive compensation, the Compensation Committee compares the Company’s pay levels and programs to those available for the Company’s competitors for executive talent and uses this comparative data as a guide in its review and determination of compensation. Our Compensation Committee annually considers and selects an appropriate peer group (consisting of biotechnology and pharmaceutical companies), based, in part, on the recommendations of FW Cook, and, for each NEO, the Compensation Committee reviews the compensation levels and practices of our peer group, which for our NEOs, other than the CEO, are based on reports prepared by management from information contained in compensation surveys and proxy statements. FW Cook provides the Compensation Committee with market data, an annual report on the compensation levels and practices of our peer group, and compensation recommendations for the CEO position.

Compensation Risk Management. In cooperation with management, FW Cook assesses the potential risks arising from our compensation policies and practices as discussed more fully below.

Compensation Risk Management

Annual Risk Management Assessment. On an annual basis, management, working with the Compensation Committee’s independent compensation consultant, conducts an assessment of the Company’s compensation policies and practices for all staff members generally, and for our staff members who participate in our sales incentive compensation program, for material risk to the Company. Compensation-related risks from COVID-19 were evaluated as part of this assessment for 2021.

Results of Risk Management Assessment.The results of this assessment are reviewed and discussed with the Compensation Committee. Based on this assessment, review and discussion, we believe that, through a combination of risk-mitigating features and incentives guided by relevant market practices and our Company performance goals, our compensation policies and practices do not present risks that are reasonably likely to have a material adverse effect on us.

Factors That Discourage Excessive Risk-Taking.In evaluating our compensation policies and practices, a number of factors were identified which the Company, the Compensation Committee, and its independent consultant believe discourage excessive risk-taking, including:

Mix of Incentives and Metrics. Our compensation programs consist of a mix of incentives and metrics (financial and operational) that are tied to varying performance periods and are designed to balance our need to drive our current performance with the need to position the Company for long-term success.

Company-wide Results.Company-wide results are the most

important factor in determining the amount of an annual cash incentive award, one of our mix of incentives, for each of our staff members.

Emphasis on Long-Term Performance. We cap short-term incentives and make LTI equity awards a component of compensation for nearly all of our full-time staff members. In particular, the CEO and the other executive officers participate in compensation plans that are designed so that the largest component of their compensation is in the form of LTI equity awards to ensure that a significant portion of their compensation is associated with long-term, rather than short-term, outcomes, which aligns these individuals’ interests with those of our stockholders.

Equity Award Grant Practices. We employ appropriate practices with respect to equity awards: we do not award mega-grants, discounted stock options, or immediately vested equity to staff members; and we have grant guidelines that generally limit the grant date for our equity grants to the third business day after our announcement of quarterly earnings.

Robust Stock Ownership and Retention Guidelines. We have robust stock ownership guidelines for vice presidents and above that require significant investment by these individuals in our Common Stock. We require that each officer who has not met his or her required ownership guidelines hold shares of our Common Stock acquired through the vesting of restricted stock units, the payout of performance units, and the exercise of stock options (net of shares retained by us to satisfy associated tax withholding requirements and exercise price amounts) until such officer has reached his or her required stock ownership level.

LOGO ï 2022 Proxy Statement37


Corporate Governance

Comprehensive Performance Evaluations. Our Company values and leadership behaviors are an integral part of the performance assessments of our staff members and are particularly emphasized in our assessment tools at higher positions. These evaluations serve as an important information tool and basis for compensation decisions.

Clawback Policy. We have a clawback policy that requires our Board to consider recapturing past cash or equity compensation payouts awarded to our executive officers if it is subsequently determined that the amounts of such compensation were determined based on financial results that are later restated and the executive officer’s misconduct caused or partially caused such restatement.

Recoupment. We have recoupment provisions that expressly allow the Compensation Committee or management, as appropriate, to consider employee misconduct that caused serious financial or reputational damage to the Company when determining whether an employee has earned an annual cash incentive award or the amount of any such award.

The Compensation Committee has adopted an executive officer equity recoupment policy that provides the Compensation Committee with the ability to cause the forfeiture and cancellation of unvested equity awards and any unexercised portion of any stock options (granted after December 31, 2020) if an executive officer is terminated for engaging in misconduct that caused serious financial or reputational damage to the Company (including, but not limited to, a financial restatement).

Disclosure. Subject to our recoupment and clawback policies and provisions, we intend to disclose the general circumstances of any application of our recoupment or clawback policies and provisions against any executive officer (current or former) and the aggregate amount of compensation recovered.

No Hedging or Pledging. Our Insider Trading Policy prohibits pledging or purchasing of our Common Stock on margin(1) and hedging the economic risk of our Common Stock (as discussed more fully below).

Mandatory Global Code of Conduct Compliance Training. We require training on our global Code of Conduct and other policies that educate our staff members on appropriate behaviors and the consequences of taking inappropriate actions.

Pricing Policies and Controls. Amgen’s drug pricing governance framework is designed to help ensure that our pricing actions around the globe are legally compliant, financially sound, and aligned with our values and corporate objectives. Our approach to pricing includes training, standard operating procedures, policies, approval mechanisms for price increases and price policy exceptions, and other controls that balance regional and country autonomy with centrally managed price discipline. Our Board, with the assistance of the Compliance Committee, has a key role in the oversight of pricing risk and regularly receives presentations from management on drug pricing practices and trends.

Prohibition on Hedging

Under our global Insider Trading Policy, all of our Board members and staff members, including our NEOs, consultants, contract workers, secondees, and temporary staff worldwide are considered “Covered Persons.” It is against the Insider Trading Policy for Covered Persons to directly or indirectly participate in transactions involving trading activities in our securities that, by their nature, are aggressive or speculative, or may give rise to an appearance of impropriety. Covered Persons may not:

Engage in short sales (sales of stock that the seller does not own or a sale that is completed by delivery of borrowed stock) with respect to our securities;

Engage in transactions that hedge or offset, or are designed to hedge or offset, any decrease in the market value of Amgen stock;

Purchase or pledge Amgen stock on margin or as collateral to secure a loan or other obligation(1); or

Enter into any derivative or similar transactions with respect to our securities.

Examples of prohibited derivative transactions include, but are not limited to, purchases or sales of puts and calls (whether written or purchased or sold), options (whether “covered” or not), forward contracts, including but not limited to prepaid variable forward contracts; put and call “collars” (“European” or “American”), “equity” or “performance” swap or exchange agreements, or any similar agreements or arrangements however denominated, in our securities.

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

38    LOGO ï 2022 Proxy Statement


Corporate Governance

Pay Ratio

Following is a reasonable estimate, prepared under applicable SEC rules, of the ratio of the annual total compensation of our CEO to the median of the annual total compensation of our other staff members, calculated in accordance with the requirements of Item 402(c)(2)(x) of Regulation S-K. The Company determined our median employee based on total direct compensation paid to all of our staff members worldwide and recorded in our global human resources systems as of December 31, 2021. Total direct compensation included base salary, annual cash incentive awards earned for the period (and target sales incentive awards for our sales force), and the annual grant value of LTI equity awards during 2021. Earnings of our staff members outside of the U.S. were converted to U.S. dollars using currency exchange rates

as of December 31, 2021. No cost-of-living adjustments were made. We then determined the annual total compensation of our median employee for 2021 which was $130,589. As disclosed in the “Summary Compensation Table” appearing on page 73, our CEO’s annual total compensation for 2021 was $21,721,154. Based on the foregoing, the ratio of the annual total compensation of our CEO to that of the median staff member was 166 to 1. For information on the determination of executive compensation, please see “Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 2021” above and our Compensation Discussion and Analysis beginning on page 41.

Compensation Committee Report

The Compensation Committee has reviewed and discussed the Compensation Discussion and Analysis with management, and based on the review and discussions, recommended to the Board of Directors that the Compensation Discussion and Analysis be included in the

Company’s 2022 Annual Meeting proxy statement and incorporated by reference into the Company’s Annual Report on Form 10-K for the year ended December 31, 2021.

Human Capital Management

Our Board has a key role in the oversight of our culture, setting the tone at the top, and holding management accountable for maintaining high ethical standards. The Board believes that human capital management, including diversity and inclusion initiatives, are important to our success. We conduct staff member engagement surveys on a regular basis and the results of these surveys are discussed with the Board.

Amgen places significant value on fostering and enabling growth for staff, both personally and professionally, and we are committed to providing a safe, healthy, innovative, and diverse work environment for our staff.

Our Social Architecture. Since Amgen’s founding in 1980, our staff members have directed their intelligence and enthusiasm toward a simple, yet powerful mission to serve patients. This clearly articulated mission, our aspiration to be the world’s best human therapeutics company, a carefully considered strategy informed by our mission and aspiration, a well-defined set of Amgen Values that define how we behave, and clear leadership attributes that we expect from our staff members, together form the “social architecture” that defines our unique culture. This social architecture is deeply rooted in our culture and has enabled Amgen’s growth over the past forty years from an early pioneer in the biotech industry to a leading innovator and world-class biologics manufacturer.

The Amgen Values were formalized in 1996 and continue to serve as the principles that guide the way we conduct business

Amgen ValuesHave Implemented Compensation Best Practices

 

Be Science-Based

Trust and Respect Each

OtherWhat we do

 

Compete Intensely and Win 

Long-term performance-based equity awards (80% of total target equity, of which 50% are three-year performance unit awards and 30% are stock options)

Ensure Quality

 

A substantial majority of NEO compensation is performance-based and at-risk

Recoupment provisions for misconduct that causes serious financial or reputational damage include forfeiture and cancellation of unvested or unexercised(1) equity awards and annual cash incentive awards being deemed not earned in full or part

Clawback policy tied to financial restatement and misconduct that permits recapture of past cash or long-term incentive equity award payouts

Robust stock ownership (6x for Chief Executive Officer) and retention guidelines

Minimum vesting periods of one year, with most equity grants vesting over four years (with no vesting in the first year and vesting in three approximately equal installments thereafter)

We use market median values as the reference point for each element of compensation at all job levels, including our NEOs

Independent compensation consultant

Amgen Values overlay our performance goals

 

Create Value for Patients,
Staff, and Stockholders

Work in Teams

Be Ethical

Collaborate, Communicate,

and Be AccountableWhat we don’t do

 

Diverse and Inclusive Workforce. We believe that an environment of inclusion and belonging fosters innovation, which drives our ability to serve patients. Our global presence is strengthened by having a workforce that reflects the diversity of the patients we serve. To that end, we established a new executive diversity, inclusion, and belonging council chaired by our CEO. With endorsement from executive management and engagement with senior leaders across the organization, we have implemented a global strategy designed to leverage our diversity and create a more inclusive workspace.

This strategy is designed to help us successfully navigate a global, complex marketplace as we bring more medicines to patients around the world. In addition, we are setting goals to improve our focus around diversity, inclusion, and belonging and Amgen is positioned to amplify our program reach across the globe and measure our progress towards creating a more inclusive workplace. Additionally, we currently have global Employee Resource Groups at our Company, all with executive sponsorship, that are organized around primary diversity attributes, including:

 

×

No alterations to our established goals to respond to changing business conditions (for example, we have not made any changes to established goals in response to the occurrence or challenges of the pandemic)

×

No hedging or pledging

×

No re-pricing or backdating

×

No tax gross-ups (except in connection with relocation)

×

No single-trigger for stock options and restricted stock units in the event of a change of control

×

No excessive perks

×

No employment agreements

×

No dividends paid on unvested equity

×

No defined benefit pension or supplemental executive retirement plan (SERP) benefits

 

Amgen Asian AssociationTHE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPROVAL OF THE

ADVISORY RESOLUTION TO APPROVE THE COMPENSATION OF THE

(AAA)COMPANY’S NAMED EXECUTIVE OFFICERS.

 

  

(1)

Forfeiture and cancellation applies to any unvested or unexercised portion of any stock options granted after December 31, 2020.

6    LOGO ï 2022 Proxy Statement


 

Amgen Black Employee Network (ABEN)Proxy Statement Summary

 

Item 3: Ratification of Selection of Independent Registered Public Accountants (Page 94)

Each year, the Audit Committee evaluates the qualifications and performance of the Company’s independent registered public accountants and determines whether to re-engage the current independent registered public accountants.

Based on this evaluation, the Audit Committee believes that the continued retention of Ernst & Young LLP, or EY, is in the best interests of the Company and its stockholders.

The Audit Committee of the Board has selected EY as our independent registered public accountants for the fiscal year ending December 31, 2022.

 

Ability Bettered through Leadership and Education (ABLE), a resource group for the physically or cognitively disabled

Amgen Early CareerTHE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” RATIFICATION OF OUR

Professionals (AECP)INDEPENDENT REGISTERED PUBLIC ACCOUNTANTS.

 

  

LOGO ï 2022 Proxy Statement7


 

Amgen Indian Subcontinent Network (AISN)Item 1 — Election of Directors

 

Item 1

Election of Directors

Under our governance documents, the Board of Directors, or Board, has the power to set the number of directors from time to time by resolution. The Board has fixed the authorized number of directors at 12 and we currently have 12 directors serving on our Board. Our Board is composed of directors with a wide range of relevant experiences and backgrounds and considers a number of attributes when seeking new candidates for the Board as discussed more fully below and in the section “Corporate Governance—Process for Selecting Directors, Director Qualifications, and Board Diversity.” Based upon the recommendation of our Governance and Nominating Committee, or Governance Committee, the Board has nominated each of the director nominees set forth below to stand for election as a director, in each case for a one-year term expiring at our 2023 annual meeting of stockholders and until his or her successor is elected and qualified, or until his or her earlier retirement, resignation, disqualification, removal, or death.

Each nominee has agreed to serve if elected and the Board has no reason to believe that any nominee will be unable to serve. However, if

any nominee should become unavailable for election prior to the 2022 Annual Meeting of Stockholders, or Annual Meeting, proxies will be voted in favor of the election of a substitute nominee or nominees proposed by the Board or, alternatively, the number of directors may be reduced accordingly by the Board. Vacancies on the Board (including any vacancy created by an increase in the size of the Board) may be filled only by a majority of the directors remaining in office, even if less than a quorum of the Board. A director elected by the Board to fill a vacancy (including a vacancy created by an increase in the size of the Board) will serve until the next annual meeting of stockholders and until such director’s successor is elected and qualified, or until such director’s earlier retirement, resignation, disqualification, removal, or death.

The independent members of the Board have elected Robert A. Eckert to continue to serve as our lead independent director, subject to his re-election to the Board by our stockholders at the Annual Meeting. As lead independent director, Mr. Eckert will continue to have the specific and significant duties as discussed under “Corporate Governance.”

Nominees to the Board

  

Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive   

 

 

 

Compensation

and

Management

Development

 

 

 

 

 

   

Equity

Award

 

 

   

Corporate  

Responsibility  

and  

Compliance  

 

 

 

 

 

Wanda M. Austin

  

 

 

  

 

67

 

  

 

2017

 

  

 

M

 

      

 

M

 

    
 

Robert A. Bradway

    

 

59

 

  

 

2011

 

      

 

C

 

    

 

M

 

  
 

Brian J. Druker

  

 

 

  

 

66

 

  

 

2018

 

        

 

M

 

    

 

M

 

 

Robert A. Eckert*

  

 

 

  

 

67

 

  

 

2012

 

    

 

M

 

  

 

M

 

  

 

C

 

    
 

Greg C. Garland

  

 

 

  

 

64

 

  

 

2013

 

    

 

C

 

  

 

M

 

  

 

M

 

    
 

Charles M. Holley, Jr.

  

 

 

  

 

65

 

  

 

2017

 

  

 

C

 

  

 

M

 

  

 

M

 

      
 

S. Omar Ishrak

  

 

 

  

 

66

 

  

 

2021

 

        

 

M

 

    

 

M

 

 

Tyler Jacks

  

 

 

  

 

61

 

  

 

2012

 

        

 

M

 

    

 

M

 

 

Ellen J. Kullman

  

 

 

  

 

66

 

  

 

2016

 

  

 

M

 

  

 

M

 

        
 

Amy E. Miles

  

 

 

  

 

55

 

  

 

2020

 

  

 

M

 

  

 

M

 

        
 

Ronald D. Sugar

  

 

 

  

 

73

 

  

 

2010

 

    

 

M

 

  

 

M

 

      

 

C

 

  

R. Sanders Williams

  

 

 

  

 

73

 

  

 

2014

 

       

 

M

 

                 

 

M

 

“*”

indicates Lead Independent Director.

“C”

indicates Chair of the committee.

“M”

indicates member of the committee.

8    LOGO ï 2022 Proxy Statement


Item 1 — Election of Directors

Summary of Director Nominee Core Experiences and Skills

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, have gained significant and wide-ranging management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees), an understanding of corporate governance practices and trends, and bring unique perspectives to the Board. A number of our directors have extensive scientific and healthcare expertise relevant to our industry, including pioneering scientific research in the areas of oncology and cardiology and experience leading important academic institutions. The Board and the Governance Committee believe the skills, qualities, attributes, experience and diversity of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director nominee. The details of each nominee’s competencies are included in each nominee’s biography.

LOGO

Experience/Skills Austin Bradway Druker Eckert Garland Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

LOGO ï 2022 Proxy Statement9


Item 1 — Election of Directors

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE NAMED NOMINEES. PROXIES WILL BE VOTED “FOR” THE ELECTION OF THE NOMINEES UNLESS OTHERWISE SPECIFIED.

Set forth below is biographical information for each nominee and a summary of the specific qualifications, attributes, skills, and experiences which led our Board to conclude that each nominee should serve on the Board at this time. All of our directors meet the qualifications and skills of our Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations included in this proxy statement as Appendix A. There are no family relationships among any of our directors or among any of our directors and our executive officers.

 

Amgen Latino EmployeeWanda M. Austin

LOGO

Director since: 2017

Age:67

Committees:

Network (ALEN)  Audit

  Compensation and Management Development

Other Public Company Boards:

  Chevron Corporation

  Virgin Galactic Holdings, Inc.

 

 

Wanda M. Austin is the retired President and Chief Executive Officer of The Aerospace Corporation, a leading architect of the United States’ national security space programs, where she served from 2008 until her retirement in 2016. From 2004 to 2007, Dr. Austin was Senior Vice President, National Systems Group of The Aerospace Corporation. Dr. Austin joined The Aerospace Corporation in 1979 and served in various positions from 1979 until 2004.

Dr. Austin was the Interim President of the University of Southern California, or USC, from 2018 to 2019 and has served as an Adjunct Research Professor at USC’s Viterbi School of Engineering since 2007. She is the co-founder of MakingSpace, Inc., where she serves as a motivational speaker on STEM education. Dr. Austin has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2016, serving on its Management Compensation Committee and chairing its Board Nominating and Governance Committee. Dr. Austin has been a director of Virgin Galactic Holdings, Inc., a commercial space flight company, since 2019 and is a member of its Safety Committee, and Chair of its Compensation Committee. Dr. Austin is a life trustee of USC, having served as a voting trustee from 2010 to March 2021, and previously served on the boards of directors of the National Geographic Society and the Space Foundation. Dr. Austin received an undergraduate degree from Franklin & Marshall College, a master’s degree from the University of Pittsburgh, and a doctorate from USC. She is a member of the National Academy of Engineering.

 

Amgen LGBTQ and Allies Network (PRIDE)Qualifications

 

The Board concluded that Dr. Austin should serve on the Board based on her leadership and management experience as a chief executive officer, her extensive background in science, technology, and government affairs in a highly regulated industry, and her public board experience.

 

Amgen Veterans EmployeesRobert A. Bradway

LOGO

Director since:2011

Age:Network (AVEN)59

Committees:

  Equity Award

  Executive (Chair)

Other Public Company Boards:

  The Boeing Company

 

 

Robert A. Bradway has served as our director since 2011 and Chairman of the Board since 2013. Mr. Bradway has been our President since 2010 and Chief Executive Officer since 2012. From 2010 to 2012, Mr. Bradway served as our Chief Operating Officer. Mr. Bradway joined Amgen in 2006 as Vice President, Operations Strategy and served as Executive Vice President and Chief Financial Officer from 2007 to 2010. Prior to joining Amgen, he was a Managing Director at Morgan Stanley in London where, beginning in 2001, he had responsibility for the firm’s banking department and corporate finance activities in Europe.

Mr. Bradway has been a director of The Boeing Company, an aerospace company and manufacturer of commercial airplanes, defense, space and securities systems, since 2016, serving as the Chair of the Finance Committee and a member of the Governance and Public Policy Committee. From 2011 to 2017, Mr. Bradway was a director of Norfolk Southern Corporation, a transportation company. He has served on the board of trustees of the University of Southern California since 2014. Mr. Bradway holds a bachelor’s degree in biology from Amherst College and a master’s degree in business administration from Harvard Business School.

Qualifications

The Board concluded that Mr. Bradway should serve on the Board based on his thorough knowledge of all aspects of our business, combined with his leadership and management skills having previously served as our President and Chief Operating Officer and as our Chief Financial Officer.

10    LOGO ï 2022 Proxy Statement


Item 1 — Election of Directors

 

Brian J. Druker

LOGO

Director since:Women Empowered2018

Age:66

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Vincerx Pharma, Inc.

Brian J. Druker joined Oregon Health & Science University, or OHSU, in 1993 and is currently a physician-scientist and professor of medicine. Dr. Druker has served as the director of the OHSU Knight Cancer Institute since 2007, associate dean for oncology of the OHSU School of Medicine since 2010, and the JELD-WEN chair of leukemia research at OHSU since 2001. He was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, from 2002 to be Exceptional (WE2)2019.

Dr. Druker has been a director of Vincerx Pharma, Inc., a biopharmaceutical company, since December 2020, and serves on its Nominating and Corporate Governance Committee. Dr. Druker has served on the scientific advisory board of Aptose Biosciences Inc., a biotechnology company, since 2013. Dr. Druker has been a consultant to Grail, Inc., a biotechnology company, since 2021, and served on its scientific advisory board, from 2016 to 2019. In 2011, he founded Blueprint Medicines Corporation, a biopharmaceutical company, and remains as a scientific advisor to this company. In 2006, he founded MolecularMD, a privately-held molecular diagnostics company that was acquired by ICON plc in 2019.

Dr. Druker has received numerous awards, including the Lasker-DeBakey Clinical Research Award in 2009, the Japan Prize in Healthcare and Medical Technology in 2012, the Albany Medical Center Prize in 2013, and the Sjöberg Prize in 2019, for influential work in the development of STI571 (Gleevec®) for the treatment of chronic myeloid leukemia. He was elected to the National Academy of Sciences in 2012 as well as the National Academy of Medicine in 2007. Dr. Druker received both an undergraduate degree and his medical doctorate from the University of California, San Diego.

Qualifications

The Board concluded that Dr. Druker should serve on the Board based on his extensive scientific research and expertise leading an important academic institution, conducting highly significant research in the area of oncology, and directly managing the care of cancer patients.

Robert A. Eckert

Lead Independent Director

LOGO

Director since:2012

Age:67

Committees:

  Compensation and Management Development (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Levi Strauss & Co.

  McDonald’s Corporation

  Uber Technologies, Inc.

Robert A. Eckert is our lead independent director. Mr. Eckert has been an Operating Partner at FFL Partners, LLC (formerly known as Friedman Fleischer & Lowe, LLP), a private equity firm, since 2014. Mr. Eckert was the Chief Executive Officer of Mattel, Inc., a toy design, manufacture and marketing company, having held this position from 2000 through 2011, and its Chairman of the Board from 2000 through 2012. He was President and Chief Executive Officer of Kraft Foods Inc., a consumer packaged food and beverage company, from 1997 to 2000, Group Vice President from 1995 to 1997, President of the Oscar Mayer Foods Division from 1993 to 1995 and held various other senior executive and other positions from 1977 to 1992.

Mr. Eckert has been a director of McDonald’s Corporation, a company that franchises and operates McDonald’s restaurants in the global restaurant industry, since 2003, serving as the Chair of the Public Policy and Strategy Committee and a member of the Executive and Governance Committees. Mr. Eckert also has served as a director of Levi Strauss & Co., a jeans and casual wear manufacturer, since 2010, serving as Chair of the Nominating, Governance and Corporate Citizenship Committee and a member of the Compensation Committee and, since March 2021, as non-executive Chair of the board. In 2020, Mr. Eckert was appointed a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, serving as Chair of the Compensation Committee and a member of the Nominating and Governance Committee. Mr. Eckert was a director of Smart & Final Stores, Inc., a warehouse store, from 2013 until 2014 prior to it becoming a publicly-traded company. He was appointed director of Eyemart Express Holdings LLC, a privately-held eyewear retailer and portfolio company of FFL Partners, LLC, in 2015. Mr. Eckert is on the Global Advisory Board of the Kellogg School of Management at Northwestern University and serves on the Eller College National Board of Advisors at the University of Arizona. Mr. Eckert received an undergraduate degree from the University of Arizona and a master’s degree in business administration from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Mr. Eckert should serve on our Board because of Mr. Eckert’s long-tenured experience as a chief executive officer and director of large public companies, his broad international experience in marketing and business development, and his valuable leadership experience.

LOGO ï 2022 Proxy Statement11


Item 1 — Election of Directors

Greg C. Garland              

LOGO

Director since:2013

Age:64

Committees:

  Compensation and Management Development

  Executive

  Governance and Nominating (Chair)

Other Public Company Boards:

  Phillips 66(1)

Greg C. Garland is the Chairman and Chief Executive Officer of Phillips 66, a diversified energy manufacturing and logistics company created through the repositioning of ConocoPhillips, having held this position since 2012. Mr. Garland chairs the Executive Committee of Phillips 66.(1) Prior to Phillips 66, Mr. Garland served as Senior Vice President, Exploration and Production, Americas of ConocoPhillips from 2010 to 2012. He was President and Chief Executive Officer of Chevron Phillips Chemical Company (now a joint venture between Phillips 66 and Chevron) from 2008 to 2010 and Senior Vice President, Planning and Specialty Chemicals from 2000 to 2008. Mr. Garland served in various positions at Phillips Petroleum Company from 1980 to 2000. Mr. Garland is a member of the Engineering Advisory Council for Texas A&M University. Mr. Garland received an undergraduate degree from Texas A&M University.

Qualifications

The Board concluded that Mr. Garland should serve on our Board because of Mr. Garland’s experience as a chief executive officer and his over 30 years of international experience in a highly regulated industry.

 

(1)

Mr. Garland served as Chairman and Chief Executive Officer of Phillips 66 Partners LP, a master limited partnership and subsidiary of Phillips 66 without any employees, until its full acquisition in March 2022 by Phillips 66.

Charles M. Holley, Jr.      

LOGO

Director since:2017

Age:65

Committees:

  Audit (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Carrier Global Corporation

  Phillips 66

Audit Committee financial expert

Charles M. Holley, Jr. is the former Executive Vice President and Chief Financial Officer for Wal-Mart Stores, Inc., or Walmart, where he served from 2010 to 2015 and as Executive Vice President in January 2016. Prior to this, Mr. Holley served as Executive Vice President, Finance and Treasurer of Walmart from 2007 to 2010. From 2005 to 2006, he served as Senior Vice President. Prior to that, Mr. Holley was Senior Vice President and Controller from 2003 to 2005. Mr. Holley served various roles in Wal-Mart International from 1994 through 2002. Prior to this, Mr. Holley served in various roles at Tandy Corporation. He spent more than ten years with Ernst & Young LLP. Mr. Holley was an Independent Senior Advisor, U.S. CFO Program, at Deloitte LLP, a privately-held provider of audit, consulting, tax, and advisory services, from 2016 to 2019.

Mr. Holley has been a director of Phillips 66 since 2019 and serves on the Audit and Finance, and Public Policy and Sustainability Committees. Mr. Holley has also been a director of Carrier Global Corporation, a provider of heating, ventilating, air conditioning (HVAC), refrigeration, fire, and security solutions, since 2020 and chairs the Audit Committee and serves as a member of the Compensation Committee. Mr. Holley serves on the Advisory Council for the McCombs School of Business at the University of Texas at Austin and the University of Texas Presidents’ Development Board.

Qualifications

The Board concluded that Mr. Holley should serve on the Board based on his experience as a chief financial officer of a global public company, his financial acumen, and his management and leadership skills. Given his financial and leadership experience, Mr. Holley has been determined to be an Audit Committee financial expert by our Board.

Attracting and Developing Talent.12    LOGO Our success dependsï 2022 Proxy Statement


Item 1 — Election of Directors

S. Omar Ishrak

LOGO

Director since:2021

Age:66

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Intel Corporation

  Compute Health Acquisition Corporation

S. Omar Ishrak has served as a director of the Company since July 2021. Dr. Ishrak was first identified to the Governance and Nominating Committee as a potential director candidate by the Chairman and certain non-employee members of the Board, including our lead independent director. He is the former Executive Chairman and Chairman of the Board of Directors of Medtronic plc, or Medtronic, a global medical technology company. Dr. Ishrak served as the Chief Executive Officer of Medtronic from 2011 to April 2020 and was Executive Chairman until December 2020. Prior to joining Medtronic, he served as President and Chief Executive Officer of GE Healthcare Systems, a provider of medical imaging and diagnostic technology and a division of GE Healthcare, from 2009 to 2011. Dr. Ishrak was President and Chief Executive Officer of GE Healthcare Clinical Systems from 2005 to 2008 and President and Chief Executive Officer of GE Healthcare Ultrasound and BMD from 1995 to 2004.

Dr. Ishrak has been a director of Intel Corporation, a multinational corporation and technology company, since 2017 and Chairman of its Board since 2020, serving as a member of the Compensation Committee and Corporate Governance and Nominating Committee. He has served as Chairman of the Board of Directors of Compute Health Acquisition Corporation, a special purpose acquisition company, since 2021. Dr. Ishrak is a member of the Board of Trustees of the Asia Society, an educational organization dedicated to promoting mutual understanding and strong partnerships between Asia and the U.S. Since 2021, Dr. Ishrak has been a senior advisor to Blackstone Life Sciences, a segment of Blackstone Inc. that invests in the biopharmaceutical and medical technology industries.

Dr. Ishrak was inducted into the American Institute for Medical and Biological Engineering College of Fellows in 2016, elected as a Fellow of King’s College London in 2017, inducted into the Bakken Society in 2020, and elected to the National Academy of Engineering in 2020. Dr. Ishrak received his undergraduate degree and doctorate from the University of London, King’s College.

Qualifications

The Board concluded that Dr. Ishrak should serve on our ability to attract and retain talent and skilled staff members. We compensate our staff membersBoard based on theirDr. Ishrak’s board and senior executive-level expertise, including his experience as chief executive officer of a global, highly regulated public company in the healthcare industry, his extensive background in medical technologies, manufacturing, international expertise and interest in Asia, and his management and leadership skills.

LOGO ï 2022 Proxy Statement13


Item 1 — Election of Directors

Tyler Jacks

LOGO

Director since:2012

Age:61

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Thermo Fisher Scientific, Inc.

Tyler Jacks joined the faculty of Massachusetts Institute of Technology, or MIT, in 1992 and is currently the David H. Koch Professor of Biology, a position he has held since 2007, and founding director of the David H. Koch Institute for Integrative Cancer Research, which brings together biologists and engineers to improve detection, diagnosis and treatment of cancer, having served as director from 2007 to 2021. Since 2021, Dr. Jacks has served as President and director of Break Through Cancer, a foundation bringing together multidisciplinary cancer research teams selected from across five participating institutions.(1) Dr. Jacks was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, from 1994 until 2021.

Dr. Jacks has been a director of Thermo Fisher Scientific, Inc., a life sciences supply company, since 2009, serving as the Chair of its Science and Technology Committee and as a member of its Strategy and Finance Committee and its scientific advisory board. In 2006, he co-founded T2 Biosystems, Inc., a biotechnology company, and served on its scientific advisory board until 2013. Dr. Jacks has served on the scientific advisory board of SQZ Biotechnologies Company, a biotechnology company, since 2015. Dr. Jacks served on the scientific advisory board of Aveo Pharmaceuticals Inc., a biopharmaceutical company, from 2001 until 2013. In 2015, Dr. Jacks founded Dragonfly Therapeutics, Inc., a privately-held biopharmaceutical company, and serves as Chair of its scientific advisory board. In 2011, he was appointed to the National Cancer Advisory Board, which advises and assists the Director of the National Cancer Institute with respect to the National Cancer Program, and served as Chair until 2016. In 2016, Dr. Jacks was named to a blue ribbon panel of scientists and advisors established as a working group of the National Cancer Advisory Board and served as co-Chair advising the Cancer MoonshotSM Task Force. Dr. Jacks was a director of MIT’s Center for Cancer Research from 2001 to 2007 and received numerous awards including the Paul Marks Prize for Cancer Research and the American Association for Cancer Research Award for Outstanding Achievement. He was elected to the National Academy of Sciences as well as the National Academy of Medicine in 2009 and received the MIT Killian Faculty Achievement Award in 2015. Dr. Jacks received an undergraduate degree from Harvard University and his doctorate from the University of California, San Francisco.

Qualifications

The Board concluded that Dr. Jacks should serve on the Board based on his extensive scientific expertise relevant to our industry, including his broad experience as a cancer researcher, pioneering uses of technology to study cancer-associated genes, and service on several scientific advisory boards and service to the National Cancer Advisory Board.

(1)

Dana-Farber Cancer Institute, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The University of Texas MD Anderson Cancer Center, Memorial Sloan Kettering Cancer Center, and the Koch Institute for Integrative Cancer Research at MIT.

14    LOGO ï 2022 Proxy Statement


Item 1 — Election of Directors

Ellen J. Kullman

LOGO

Director since: 2016

Age:66

Committees:

  Audit

  Governance and Nominating

Other Public Company Boards:

  Dell Technologies Inc.

  Goldman Sachs Group, Inc.

Audit Committee financial expert

Ellen J. Kullman is President and Chief Executive Officer of Carbon, Inc., or Carbon, a privately-held 3D printing company, having held this position since 2019, and has served as a director of Carbon since 2016. She is the former President, Chair and Chief Executive Officer of E.I. du Pont de Nemours and Company, or DuPont, a science and technology-based company, where she served from 2009 to 2015. Prior to this, Ms. Kullman served as President of DuPont from 2008 to 2009. From 2006 through 2008, she served as Executive Vice President of DuPont. Prior to that, Ms. Kullman was Group Vice President, DuPont Safety and Protection. Ms. Kullman has been a director of Goldman Sachs Group, Inc., an investment banking firm, since 2016, serving on its Compensation and Corporate Governance and Nominating Committees and chairing its Public Responsibilities Committee. Ms. Kullman has been a director of Dell Technologies Inc., a technology company, since 2016, serving on its Audit Committee. Ms. Kullman served as a director of United Technologies Corporation, a technology products and services company, from 2011 (and as lead director from 2018), serving on its Compensation, Finance and Executive Committees, until its merger with Raytheon Company in 2020. Ms. Kullman served as a director of General Motors, from 2004 to 2008, serving on its Audit Committee.

Ms. Kullman has served on the Board of Trustees of Northwestern University since 2016 and is a Trustee Emerita of Tufts University School of Engineering, having served on its Board of Advisors since 2006. She served as Chair of the US-China Business Council from 2013 to 2015. Since 2016, Ms. Kullman has been a member of the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Ms. Kullman received a bachelor of science in mechanical engineering degree from Tufts University and a master’s degree from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Ms. Kullman should serve on the Board based on her lengthy global experience as chief executive officer and board chair at both public and private companies, her management and leadership skills, and her experience with scientific operations, all of which provide valuable insight into the operations of our Company. Given her leadership and financial experience, Ms. Kullman has been determined to be an Audit Committee financial expert by our Board.

Amy E. Miles

LOGO

Director since: 2020

Age:55

Committees:

  Audit

  Governance and Nominating

Other Public Company Boards:

  Gap Inc.

  Norfolk Southern Corporation

Audit Committee financial expert

Amy E. Miles was the Chief Executive Officer and a director of Regal Entertainment Group, Inc., or Regal Entertainment, a leading theatre exhibition company, having held these positions from 2009 through 2018, and its Chair of the Board from 2015 to 2018. From 2002 to 2009, Ms. Miles served as Executive Vice President, Chief Financial Officer and Treasurer of Regal Entertainment. Ms. Miles also served as Chief Executive Officer of Regal Cinemas, Inc., or Regal Cinemas, from 2009 to 2018, and its Executive Vice President, Chief Financial Officer and Treasurer from 2000 to 2009. Ms. Miles joined Regal Cinemas in 1999 as Senior Vice President of Finance. Previously, Ms. Miles was with Deloitte & Touche, LLP and PricewaterhouseCoopers LLP.

Ms. Miles has been a director of Norfolk Southern Corporation, a transportation company, since 2014, and serves on the Executive Committee, the Governance and Nominating Committee, and chairs the Audit Committee, and, beginning in May 2022, will serve as non-executive Chair of the board and cease serving as Chair of the Audit Committee, but will remain a member of the Audit Committee. Ms. Miles has been a director of The Gap, Inc., an apparel retail company, since 2020, and chairs the Audit and Finance Committee. Ms. Miles was a director of National CineMedia, Inc., a cinema advertising company, from 2011 to 2015. She was a director of Townsquare Media, Inc., a radio, digital media, entertainment, and digital marketing solutions company, from 2014 until 2016.

Ms. Miles has been a director of ASM Global, a privately-held entertainment and venue management company, since 2019. Ms. Miles serves on the boards of trustees of the University of Tennessee and the Boys and Girls Club of Eastern Tennessee.

Qualifications

The Board concluded that Ms. Miles should serve on our Board based on Ms. Miles’ board and senior executive-level expertise, including her experience as chief executive officer and chief financial officer of a large public company and her extensive finance, accounting, and management expertise in marketing and strategic planning, and public board experience. Given her leadership and financial experience, Ms. Miles has been determined to be an Audit Committee financial expert by our Board.

LOGO ï 2022 Proxy Statement15


Item 1 — Election of Directors

Ronald D. Sugar

LOGO

Director since:2010

Age:73

Committees:

  Corporate Responsibility and Compliance (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Apple Inc.

  Chevron Corporation

  Uber Technologies, Inc.

Ronald D. Sugar is the retired Chairman of the Board and Chief Executive Officer of Northrop Grumman Corporation, a global aerospace and defense company, having held these posts from 2003 through 2009.

Dr. Sugar has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2005, serving as the lead director and on the Management Compensation Committee and the Board Nominating and Governance Committee. Dr. Sugar has been a director of Apple Inc., a manufacturer and seller of, among other things, personal computers, mobile communication and media devices, since 2010, chairing the Audit and Finance Committee. Dr. Sugar has been a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, since 2018, serving as the Chair of the board of directors and chairing the Nominating and Governance Committee and serving on the Compensation Committee. Dr. Sugar served as a director of Air Lease Corporation, an aircraft leasing company, from 2010 to 2020, and chaired its Compensation Committee and served on the Nominating and Corporate Governance Committee. Since 2010, he has been a senior advisor to Ares Management LLC, a privately-held asset manager and registered investment advisor. In 2014, Dr. Sugar joined the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Dr. Sugar is a member of the National Academy of Engineering, trustee of the University of Southern California, member of the UCLA Anderson School of Management Board of Advisors, and director of the Los Angeles Philharmonic Association.

Qualifications

The Board concluded that Dr. Sugar should serve on our Board because of Dr. Sugar’s board and senior executive-level expertise, including his experience as chief executive officer and board chair of a large, highly regulated, public company and his insight in the areas of operations, government affairs, science, technology and finance.

R. Sanders Williams

LOGO

Director since:2014

Age:73

Committees:

  Corporate Responsibility and Compliance

  Governance and Nominating

Other Public Company Boards:

  Laboratory Corporation of America Holdings

  Tenaya Therapeutics, Inc.

R. Sanders Williams is the President Emeritus of Gladstone Institutes, a non-profit biomedical research enterprise, having served in this position since 2018, and was the Chief Executive Officer of the Gladstone Foundation, a not-for-profit organization supporting the Gladstone Institutes during 2018. Dr. Williams has served as Professor of Medicine at Duke University since 2018 and, from February 2021 to January 2022, acted as Interim Vice President for Research and Innovation. He has been a Professor of Medicine at the University of California, San Francisco since 2010. Dr. Williams was both President of Gladstone Institutes and its Robert W. and Linda L. Mahley Distinguished Professor of Medicine, from 2010 to 2017. Prior to this, Dr. Williams served as Senior Vice Chancellor of the Duke University School of Medicine from 2008 to 2010 and Dean of the Duke University School of Medicine from 2001 to 2008. He was the founding Dean of the Duke-NUS Graduate Medical School, Singapore, from 2003 to 2008 and served on its Governing Board from 2003 to 2010. From 1990 to 2001, Dr. Williams was Chief of Cardiology and Director of the Ryburn Center for Molecular Cardiology at the University of Texas, Southwestern Medical Center.

Dr. Williams has been a director of the Laboratory Corporation of America Holdings, a diagnostic technologies company, since 2007, serving on the Audit Committee and chairing the Quality and Compliance Committee. Since 2016, Dr. Williams also has served as a director of Tenaya Therapeutics, Inc., a biotechnology company, chairing the Compensation Committee. Tenaya Therapeutics, Inc. was a privately-held company until July 2021 when it became publicly traded. Dr. Williams was a director of Bristol-Myers Squibb Company, a pharmaceutical company, from 2006 until 2013. Dr. Williams has served on the board of directors of the Gladstone Foundation, a non-profit institution that is distinct from Gladstone Institutes, since 2012. Dr. Williams was elected to the National Academy of Medicine in 2002. Dr. Williams received his undergraduate degree from Princeton University and his medical doctorate from Duke University.

Qualifications

The Board concluded that Dr. Williams should serve on the Board because of his broad medical and scientific background, including his leadership roles in domestic and academic science settings, his deep experience in cardiology, oversight of governance of multi-hospital healthcare provider systems, leadership and performance, provide wellness resources, as well as support employeesdevelopment of international medical programs in giving backAsia, and volunteeringprior industry board experience.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE ABOVE 12 NAMED NOMINEES.

16    LOGO ï 2022 Proxy Statement


Corporate Governance

Corporate Governance

Board of Directors Corporate Governance Highlights

Our Board of Directors, or Board, is governed by our Amgen Board of Directors Corporate Governance Principles which are amended from time to time to incorporate certain current best practices in their local communities.corporate governance. Our Corporate Governance Principles may be found on our website at www.amgen.com(1) and are available in print upon written request to the Company’s Secretary at our principal executive offices at One Amgen has added transgender benefitsCenter Drive, Thousand Oaks, California 91320-1799. The Board’s corporate governance practices and continues to pride itself on industry-leading, family-friendly offerings for families of all compositions.stockholder rights include the following:

Board Governance Practices

Lead Independent Director. The independent members of the Board elect a lead independent director on an annual basis. The lead independent director has robust responsibilities and authorities as discussed below. Robert A. Eckert currently serves as our lead independent director.

Regular Executive Sessions of Independent Directors. Our independent directors meet privately on a regular basis. Our lead independent director presides at such meetings.

Board Access to Management. We afford our directors ready access to our management. Key members of management attend Board and committee meetings to present information concerning various aspects of the Company, its operations, and results, and have regular meetings in executive sessions with the Board and committees.

Board Authority to Retain Outside Advisors. Our Board and its committees have the authority to retain independent advisors and counsel. The Audit Committee has the sole authority to appoint, compensate, retain, and oversee the independent registered public accountants. The Compensation and Management Development Committee, or Compensation Committee, has the sole authority to appoint, compensate, retain, and oversee compensation advisors for senior management compensation review. The Governance and Nominating Committee, or Governance Committee, has the sole authority to appoint, retain, and replace search firms to identify director candidates and compensation advisors for our directors’ compensation review.

Independent Board Members on Key Standing Committees. The Board has four key standing committees: the Governance Committee; Audit Committee; Corporate Responsibility and Compliance Committee, or Compliance Committee; and Compensation Committee. Each member on key standing committees has been determined by the Board to be independent

under The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission, or SEC.

Regular Board and Committee Evaluations. The Board and the Audit, Compensation, Compliance, and Governance Committees each conduct an annual evaluation process. We provide more information regarding the Board and committee evaluations on page 27.

Management Succession Oversight. Our Board oversees Chief Executive Officer, or CEO, and senior management succession planning. Directors engage with potential CEO, executive, and senior management successors at Board and committee meetings. All independent members of the Board are invited to attend the Compensation Committee session on succession. Our Board also establishes steps to address succession to respond to unexpected vacancies in the event of an emergency.

Solicitation of Stockholder Perspectives. The Board believes that engagement with stockholders is a source of valuable information and perspectives on the Company. The Board has requested that management solicit input from investors on behalf of the Board and the lead independent director has also met directly with stockholders when appropriate. We provide more information regarding our stockholder engagement program on pages 31 and 51.

Majority Approval Required for Director Elections. If an incumbent director up for re-election at a meeting of stockholders fails to receive a majority of the votes cast in favor for his or her election in an uncontested election, the Board will adhere to the director resignation policy as provided in our Amended and Restated Bylaws of Amgen Inc., or Bylaws.

Director Limitation on Number of Boards. A director who is currently serving as our CEO should not serve on more than two outside public company boards. No director should serve on more than five outside public company boards. As part of its nominating process, the Governance Committee conducts an annual review of director commitment levels and shares its findings with the Board.

ContinuousBoard Refreshment. We have added seven new members to our Board since 2015 and our average Board tenure is approximately 6 years.

Director Retirement Age. The Board has established a retirement age of 75. A director is expected to retire from the Board on the day of the annual meeting of stockholders following his or her 75th birthday.

 

 

(1) 

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

 

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Item 2 — Advisory Vote to Approve Our Executive CompensationCorporate Governance

 

 

 

 

 

Director Changes in Circumstances Actively Evaluated. If a director has a significant change in principal business or professional affiliation or responsibility, including a change in principal occupation, he or she shall offer his or her resignation to the Chair of the Governance Committee. The Governance Committee then determines whether to accept the resignation based on what it believes to be in the best interests of the Company and our stockholders. Directors notify the Chair of the Governance Committee prior to accepting an invitation to serve on a public or private company board to permit the Governance Committee to evaluate the relationship for a potential conflict of interest and to confirm that the director continues to have time available to perform his or her duties.

Director Outside Relationships Require Pre-Approval. Without the prior approval of disinterested members of the Board, directors should not enter into any transaction or relationship with the Company in which they will have a financial or a personal interest or any transaction that otherwise involves a conflict of interest.

Active Management of Director Conflicts of Interest. If an actual or potential conflict of interest arises for a director or a situation arises giving the appearance of an actual or potential conflict, the director must promptly inform the Chairman of the Board or the Chair of the Governance Committee. All directors are expected to recuse themselves from any discussion or decision found to affect their personal, business, or professional interests.

Stockholder Rights

Single Class of Shares. We have a single class of shares with equal voting rights. One share equals one vote.

Proxy Access. Our Bylaws permit proxy access for director nominations. Eligible stockholders with an ownership threshold of 3% who have held their shares for at least 3 years and who otherwise meet the requirements set forth in our Bylaws may have their nominees up to the number of directors constituting the greater of 20% of the total number of directors or two nominees of our Board included in our proxy materials. Up to 20 eligible stockholders may group together to reach the 3% ownership threshold. In the course of designing our proxy access provisions, we carefully considered each element in the interest of our stockholders as a whole, including that the number of stockholders who may group together (20) would afford those stockholders likely to utilize proxy access with the opportunity to do so.

Action by Written Consent. Our Amgen Inc. Restated Certificate of Incorporation permits stockholders to act by written consent in lieu of a meeting upon the request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements of our Certificate of Incorporation.

Special Meetings. Our Bylaws permit stockholders to request that the Company call a special meeting upon the written request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements set forth in our Bylaws.

No Supermajority Vote Provisions. We have a simple majority voting standard to amend our Certificate of Incorporation and Bylaws.

No Poison Pill. We do not have a shareholder rights plan, or poison pill.

Item 2Leadership Structure

Advisory Vote to Approve Our Executive Compensation

 

 

This advisory stockholder vote, commonly knownOur current leadership structure and governing documents permit the roles of Chairman and CEO to be filled by the same or different individuals.

Annual Evaluation of Leadership Structure and Annual Election of Lead Independent Director. The Board evaluates, considers, and discusses the leadership structure annually. As part of this annual evaluation process, the Board reviews its leadership structure, including whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders. The Board also considers:

The effectiveness of the policies, practices, and people in place at the Company to help ensure strong, independent Board oversight;

The Company’s performance and the effect the leadership structure could have on its performance;

The Board’s performance and the effect the leadership structure could have on the Board’s performance;

The Chairman’s performance in the role;

The lead independent director’s performance in the role;

The views of the Company’s stockholders; and

The practices at other companies and trends in governance.

In the circumstance that the Board determines that it remains in the best interests of the Company and its stockholders that the CEO serve as “Say on Pay,” gives you,Chairman, the independent members of the Board then elects a lead independent director from the independent members of the Board. The last review was completed in March 2022, and as a result of such review, the Board has determined that it continues to be in the best interests of the Company and our stockholders to have Robert A. Bradway, our CEO and President, serve as Chairman, coupled with an active lead independent director. As such, Mr. Bradway holds the position of Chairman, CEO, and President, and Mr. Eckert serves as the lead independent director.

Overview of Lead Independent Director Responsibilities. The responsibilities of the lead independent director are well-defined. The lead independent director engages in regular communication with the independent directors, including in independent directors sessions. The lead independent director keeps Mr. Bradway apprised of any concerns, issues, or determinations made during the independent sessions, and consults with Mr. Bradway on other matters pertinent to the Company and the Board.

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Lead Independent Director Responsibilities

The lead independent director’s responsibilities outlined in our Corporate Governance Principles include:

   Approving meeting agendas for the Board;

   Assuring that there is sufficient time for discussion of all meeting agenda items;

   Previewing the information to be provided to the Board;

   Having the authority to call meetings of the independent directors;

   Organizing and leading the Board’s evaluation of the CEO;

   Serving as a liaison between the Chairman and the independent directors;

   Leading the Board’s annual self-evaluation;

   Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

   Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

In addition to the responsibilities outlined above, our lead independent director also:

Meets with the Chairman prior to each regular meeting of the Board and its committees to discuss, provide input on, and approve the agendas;

With the Chairman, determines who attends Board meetings, such as members of management or outside advisors, and presenters;

Has one-on-one discussions with each independent director, including as part of the Board’s annual evaluation process;

Attends all committee meetings, including those committees for which he is not a member (at his discretion) and has access to all committee materials;

Has the authority to engage independent consultants;

Is regularly apprised of inquiries from stockholders;

Interviews Board candidates; and

Has an increased role in crisis and risk management, as appropriate.

Independent Directors Sessions. A meeting of the independent directors is scheduled at every regular Board meeting and the independent directors meet in an executive session without Mr. Bradway to review matters, including Company performance, management effectiveness, proposed programs and transactions, and the Board meeting agenda items. These independent sessions are organized and chaired by our lead independent director and our lead independent director provides direct feedback to Mr. Bradway after these executive sessions.

Independent Committee Leadership. The Audit, Compensation, Compliance, and Governance Committees are each composed solely of,

and led by, independent directors and provide independent oversight of management and its Board-delegated duties. In addition:

Each committee Chair meets with management in advance of meetings to review and refine agendas, add topics of interest, and review and comment on materials to be delivered to the committee;

Every director has access to all committee materials;

Each committee Chair provides a report summarizing committee meetings to the full Board at each regular meeting of the Board;

Each committee meeting includes adequate time for executive session and the committees meet in executive session on a regular basis with no members of management present (unless otherwise requested by the committee); and

Each committee effectively manages its Board-delegated duties and communicates regularly with the Chairman, lead independent director, the Board, and members of management.

Furthermore, the Compensation Committee has an effective process for succession planning and for monitoring and evaluating Mr. Bradway’s compensation and performance.

Lead Independent Director. Following the annual re-evaluation of our corporate governance structure, Mr. Eckert has been elected as the lead independent director each year since our May 2016 annual meeting of stockholders and was re-elected by our Board on March 2, 2022 to continue to serve as lead independent director subject to his re-election to the Board by our stockholders at the 2022 Annual Meeting.

Corporate Governance Structure. The Board believes our corporate governance structure, with its strong emphasis on Board independence, an active lead independent director, and strong Board and committee involvement, provides sound and robust oversight of management.

Benefits of Combined Leadership Structure. Following the annual evaluation of the governance structure, the Board continues to believe that the Company and our stockholders are best served by having Mr. Bradway in the role of Chairman (subject to his re-election to the Board) and CEO for the following reasons:

Mr. Bradway is most familiar with our business and the unique challenges we face. Mr. Bradway’s day-to-day insight into our challenges facilitates timely deliberation by the Board of important matters.

Mr. Bradway has and will continue to identify agenda items and lead effective discussions on the important matters affecting us. Mr. Bradway’s knowledge and extensive experience regarding our operations and the highly-regulated industries and markets in which we compete position him to identify and prioritize matters for Board review and deliberation.

As Chairman and CEO, Mr. Bradway serves as an important bridge between the Board and management and provides critical leadership for carrying out our strategic initiatives and confronting our challenges. The Board believes that Mr. Bradway brings a

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Corporate Governance

unique, stockholder-focused insight to assist the Company to most effectively execute its strategy and business plans to maximize stockholder value.

The strength and effectiveness of the communications between Mr. Bradway as our Chairman and Mr. Eckert as our lead independent director result in comprehensive Board oversight of the issues, plans, and prospects of our Company.

This leadership structure provides the Board with more complete and timely information about the Company, a unified structure and

consistent leadership direction internally and externally and provides a collaborative and collegial environment for Board decision making.

Flexibility of the Leadership Structure. The Board is committed to high standards of corporate governance. The Board values its flexibility to select its optimal leadership structure to best serve the Company’s and stockholders’ best interests based on the qualifications of individuals available, circumstances existing at the time, and Company’s particular needs. As such, the Board annually evaluates whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders.

The Board’s Role in Risk Oversight

Our Board oversees an enterprise-wide approach to risk management, which is designed to support execution of our strategy and achievement of the Company’s objectives to improve long-term operational and financial performance and enhance stockholder interests. Our Board believes that a fundamental part of risk management is understanding the opportunityrisks that we face, adopting appropriate controls and mitigation activities for such risks, monitoring these risks, and responding to endorseemerging developments for such risks.

We have a Company-wide Enterprise Risk Management, or ERM, program, to identify, assess, manage, report, and monitor enterprise-level risks that may affect our ability to achieve the Company’s objectives. The ERM program is overseen by our Executive Vice President and Chief Financial Officer and chaired by our Chief Audit Executive. Annually, we evaluate the greatest risks to our business, their underlying risk drivers, and the associated mitigation activities, maturity, and controls. Our Enterprise Risk Council, a cross-functional group of the Company’s business leaders representing all key business functions, works to identify and assess risks that meet the pre-established criteria constituting an enterprise-level risk, and confirms that there is clear accountability and appropriate mitigation plans are in place, including monitoring and reporting. Additionally, emerging risks that do not endorserise to the level of enterprise-level risks, are assessed, discussed, and actively managed and monitored. We believe that the areas of risk that are fundamental to the success of our enterprise and rise to enterprise-level risks include the areas of product development, safety and surveillance, supply and quality, value (which includes pricing) and access, sales and promotion, business development, as well as protecting our assets (financial, intellectual property, and information, including cybersecurity), all of which are managed by senior executive paymanagement reporting directly to our CEO.

The enterprise-level risks are overseen by the Board and the appropriate Board committee (as discussed below). The Board receives regular risk reporting from senior management, including an annual detailed review of the ERM program and policies. Accordingly, youkey enterprise-level and emerging risks, as well as during the Board’s annual strategic planning process, annual budget reviews and approvals, capital plan review and approval, and through reviews of compliance issues at the applicable committees of our Board, as appropriate. For example, the risks associated with COVID-19 have the potential to affect areas of enterprise-level risk overseen by our Board, Audit Committee, Compensation Committee, and Compliance Committee and, as such, our risk mitigation plans and the effects of COVID-19 have been a topic regularly brought to and reviewed by the Board and its committees. For topics allocated to specific committees for their oversight, such as antitrust and competition regulation that is an area of the Compliance Committee’s responsibilities (as discussed below), the Compliance Committee Chair oversees the Compliance Committee’s annual calendar and meeting agendas to determine that the Company’s activities in support of its compliance with antitrust and competition regulation are being askedassessed regularly, including a full annual review that includes Amgen’s policies, processes, and training to cast an advisory votesupport such compliance, as well as regular updates of any significant industry developments at each Compliance Committee meeting. As is the practice for each of our committee Chairs, the Compliance Committee Chair reports out on these and other activities to the Board for its information and oversight at each regular Board meeting.

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Each Board committee has primary risk oversight responsibility that is aligned with its areas of focus. At each regular meeting, or more frequently as needed, the Board receives and considers committee reports, and such reports may provide additional detail on risk management issues and management’s response.

  Committee

Primary Risk Oversight Responsibility

  Governance and Nominating

   Oversees governance risk, including the assessment of each member of the Board’s independence, as well as the compliance with our Corporate Governance Principles and Board of Directors’ Code of Conduct. Also oversees Board and committee evaluations and Board succession.

  Audit

   Oversees internal controls over financial reporting, as well as internal audit and independent registered public accountants, as well as financial risk, such as capital risk, tax risk, sourcing risk, and financial compliance risk.

  Compensation and Management Development

   Oversees human capital management, as well as executive talent management, development, and succession planning. Also oversees our compensation policies and practices and incentive program administration and design, including whether such policies, practices, and incentive programs balance risk-taking and rewards in an appropriate manner (as discussed further below), align with stockholders’ interests, and are consistent with emerging best practices. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities, previously overseen by the Compliance Committee, moved to the Compensation Committee.

  Corporate Responsibility and Compliance

   Oversees non-financial compliance risk, such as regulatory risks associated with the requirements of U.S. federal health care programs, Food and Drug Administration and other regulatory agencies, and risks associated with privacy, trade compliance, antitrust and competition, anti-bribery and anti-corruption), information systems and security (including cybersecurity), value (which includes pricing) and access, government affairs, aspects of labor and employment activities and diversity, inclusion, and belonging(1), aspects of environmental sustainability, social responsibility, and corporate governance, or ESG (including environmental sustainability, corporate philanthropy, and pricing philosophy and practice), and our reputation. Also oversees staff member compliance with the global Code of Conduct.

COVID-19 Impacts to Enterprise Risk and Our Response. The far-reaching effects of COVID-19 prompted the Company to consider enterprise risk focused on rare, but high-impact events, such as global pandemics. Our business resilience program is designed to enable us to effectively prepare for and respond to crisis incidents at the global, regional, and local levels. Since the beginning of the pandemic in early 2020, we have activated appropriate crisis management and business

continuity plans and responded to the challenges presented to the operations of our business and focused on the compensationexperiences of our Named Executive Officers,customers, patients, staff members, and communities. Multiple enhancements were made to our overall resilience during this pandemic, including investments in systems, automation, and innovation designed to support our remote work environment.

(1)

Responsibility of the Compliance Committee in 2021. Responsibility for these activities moved to the Compensation Committee for 2022.

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Responding to COVID-19

In the second year of the pandemic, we continued to focus on the health and safety of our staff members and the effective operation of our business, while undertaking activities to help address the pandemic, such as manufacturing COVID-19 antibody material with Eli Lilly & Company.

Our Employees. Creating a safe and healthy workplace for our staff is a priority at Amgen. Staff member access to our facilities has been in accordance with applicable government health and safety protocols and guidance issued in response to the COVID-19 pandemic and we have taken additional safety measures, including implementing occupancy limits, restricting business travel, providing personal protective equipment, temperature screening, and COVID-19 testing. In 2021, we required staff members in the U.S. and Puerto Rico to be fully vaccinated against COVID-19.(1)

Supply of Our Medicines to Patients. To date, our remote working arrangements have not significantly affected our ability to maintain

critical business operations. We have been able to serve physicians and patients as we have avoided disruptions to delivery and shortages of our supply of medicines.

Helping Our Communities. Amgen and The Amgen Foundation, Inc., a separate legal entity entirely funded by Amgen (Amgen Foundation), have been deeply engaged with our communities during the COVID-19 pandemic. For example, since the start of the pandemic, we committed $12.5 million to support local emergency response efforts in our U.S. and international communities, patient-focused organizations mounting their own response efforts, and international relief efforts by Direct Relief and International Medical Corps. Additionally, the free online learning programs supported by the Amgen Foundation, including LabXchange and the Khan Academy, have helped students continue their science education during school closures.

Codes of Business Conduct

Our Board has adopted two codes of business conduct – the Amgen Board of Directors’ Code of Conduct that applies to our Board and a global Code of Conduct that applies to our Board, all our staff, and others conducting business on our behalf. Annual training on the global Code of Conduct is required and our Board participates in such training. We also have a code of ethics for senior financial officers. To view our

codes of business conduct and ethics, please visit our website at www.amgen.com.(2) We intend to disclose any future amendments to certain provisions of our codes of business conduct and ethics, or NEOs,waivers of such provisions, applicable to our directors and executive officers on our website if such disclosure is required by SEC or NASDAQ rules. There were no waivers of any of our codes of business conduct or code of ethics in 2021.

Board Meetings

The Board held 7 meetings in 2021 and all of the directors attended at least 75% of the total number of meetings of the Board and committees on which they served. S. Omar Ishrak was appointed to the Board effective in July 2021 and attended all of the meetings of the Board and of the committees on which he served after the date of his

appointment. It is the Company’s policy that all current directors attend our annual meetings of stockholders barring unforeseen circumstances or irresolvable conflicts. Each of our directors serving at the time of our 2021 Annual Meeting were present at our 2021 Annual Meeting.

Communication with the Board

Our annual meeting of stockholders provides an opportunity each year for stockholders to ask questions of our lead independent director and other members of the Board on appropriate matters. In addition, stockholders may communicate in writing with any particular director, any committee of the Board, or the directors as discloseda group, by sending such written communication to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799. Copies of written communications received at such address will be provided to the Board or the relevant director unless such communications are considered, in the reasonable judgment of our Secretary, to be inappropriate for submission to the intended recipient(s). Examples of stockholder communications that would be considered inappropriate for submission to the Board include, without

limitation, customer complaints, solicitations, communications that do not relate directly or indirectly to our business, or communications that relate to improper or irrelevant topics. The Secretary or his designee may analyze and prepare a response to the information contained in communications received and may deliver a copy of the communication to other Company staff members or agents who are responsible for analyzing or responding to complaints or requests. Communications concerning potential director nominees submitted by any of our stockholders will be forwarded to the Chair of the Governance Committee. For information on our engagement with our stockholders since the 2021 Annual Meeting, please see page 51 of our Compensation Discussion and Analysis (pages 38 through 65)Analysis.

(1)

This vaccination requirement did not apply to staff who were unable to receive a COVID-19 vaccine because of qualifying medical or religious reasons.

(2)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Board Committees and relatedCharters

The Board has four key standing committees: the Governance Committee; Audit Committee; Compliance Committee; and Compensation Committee. The Compensation Committee has delegated certain responsibilities to an Equity Award Committee. In addition, an Executive Committee of the Board has all of the powers and authority of the Board in the management of our business and affairs, except with respect to certain enumerated matters, including Board composition and compensation, tableschanges to our Certificate of Incorporation, or any other matter expressly prohibited by law or our

Certificate of Incorporation. The Executive Committee did not meet in 2021. The Board maintains charters for each of its standing committees and these charters are evaluated annually. In addition, the Board has adopted a written set of Corporate Governance Principles and the narrativeAmgen Board of Directors’ Code of Conduct that generally formalize practices we have in place. To view the charters of our standing Board committees, our Corporate Governance Principles, and the Board of Directors’ Code of Conduct, please visit our website at www.amgen.com.(1)

Governance and Nominating Committee

Current Members:

Greg C. Garland (Chair)

Robert A. Eckert

Charles M. Holley, Jr.

Ellen J. Kullman

Amy E. Miles

Ronald D. Sugar

R. Sanders Williams

Number of Meetings Held in 2021: 5

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

Description and Key Responsibilities:

   Determines Board membership qualifications and maintains, with the approval of the Board, guidelines for selecting nominees to serve on the Board and considering stockholder recommendations for nominees. The Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement as Appendix A.

   Selects, evaluates, and recommends to the Board nominees to stand for election at the annual meeting of stockholders and to fill vacancies as they arise as more fully described in “Process for Selecting Directors, Director Qualifications, and Board Diversity” below.

   Recommends to the Board the appointment of a lead director.

   Reviews the performance of the Board and its committees and is responsible for ensuring the availability of an orientation program for new Board members and director education.

   Recommends to the Board nominees for appointment as executive officers and certain other officers.

   Evaluates and makes recommendations to our Board regarding compensation for non-employee Board members, including minimum retention and ownership levels of Company stock by Board members. (Any Board member who is also an employee of the Company does not receive separate compensation for service on the Board.)

   Monitors the independence of the Board and evaluates questions of possible conflicts of interest of members of the Board.

   Oversees the Board’s Corporate Governance Principles and the Amgen Board of Directors’ Code of Conduct applicable to members of the Board.

The Governance Committee has authority to delegate these functions to a subcommittee of its members, but no delegation of authority was made in 2021.

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Summary of Current Director Core Experiences and Skills

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, and have gained significant and diverse management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Many of our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees) and an

understanding of corporate governance practices and trends, scientific expertise and healthcare industry experience, and bring unique perspectives to the Board. The Board and the Governance Committee believe the skills, qualities, attributes, experience, and variety of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our Company’s evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director currently represented on our Board. The details of each director nominee’s competencies are included in each director nominee’s biography.

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Experience/Skills Austin Bradway Druker Eckert Garland Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

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Board Tenure 2 <3 Years 4 3-6 Years 4 2 7-9 Years ~6 Years Average Board Tenure Continuous Board Refreshment 7 new directors since 2015 Board Diversity Highlights Gender Diversity Racial/Ethnic Diversity 3 25% Female Directors 9 2 17% Diverse Directors 10 100% Independent directors on key standing committees

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In compliance with NASDAQ’s Board Diversity Rule, the table below provides certain highlights of the composition of our Board members and nominees.

Board Diversity Matrix (As of January 20, 2022)
  

Total Number of Directors

 12
   
  Female   Male  
 

Part I: Gender Identity

   

Directors

 3   9  
 

Part II: Demographic Background

   

African American or Black

 1   –  
   

Asian

 –   1  
   

White

 2   8  

Process for Selecting Directors, Director Qualifications, and Board Diversity

Board Composition. Board composition is one of the most critical areas of focus for the Board. Reflecting our Board’s commitment to refreshment, the Board has appointed seven new directors since 2015, including women as well as those from underrepresented communities, adding critical skills and experience to our Board in furtherance of our strategic priorities.

Our Governance Committee regularly screens and recommends candidates for nomination by the full Board and, among other things, considers feedback received during the annual Board and committee evaluation process, investor feedback, our qualification guidelines and skills matrix, director commitment levels (with consideration given to public company leadership roles and outside commitments) and diversity. The Governance Committee will consider recommendations for director candidates made by stockholders and evaluate them using the same criteria as for other candidates.

Director Qualifications and Board Diversity. Our Governance Committee is responsible for determining Board membership qualifications and for selecting, evaluating, and recommending to the Board nominees for annual election to the Board and to fill vacancies as they arise. The Governance Committee reviews regularly and reports to the Board on the composition and size of the Board, and makes recommendations, as necessary, so that the Board maintains at least the minimum number of independent directors required by applicable laws and regulations, composition requirements of the Audit and Compensation Committees, and reflects the appropriate balance of knowledge, experience, skills, expertise, and diversity advisable and required by applicable laws and regulations for the Board as a whole.

The Governance Committee and Board view diversity as a priority, considers diversity in its determinations, and seeks representation across a range of attributes. Diversity includes race, ethnicity, age, and gender and is also broadly construed to take into consideration many

other factors, including industry knowledge, operational experience, scientific and academic expertise, geography, and personal background. In an effort to best support maintaining and expanding the diversity of our Board, our Governance Committee actively seeks diverse candidates, including women and minority candidates, as part of its search for new directors.

The Governance Committee determines and oversees guidelines for selecting nominees to serve on the Board and for considering stockholder recommendations for nominees. The Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement (pages 66 through 82)as Appendix A.

Among other things, under the Board of Directors Guidelines for Director Qualifications and Evaluations, each Board member must possess:

A demonstrated breadth and depth of management and leadership experience;

Financial and/or business acumen or relevant industry or scientific experience;

Integrity and high ethical standards;

Sufficient time to devote to the Company’s business;

The ability to oversee, as a director, the Company’s business and affairs for the benefit of our stockholders;

The ability to comply with the Amgen Board of Directors’ Code of Conduct; and

A demonstrated ability to think independently and work collaboratively.

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Continuous Board Refreshment

Our Board is committed to strong refreshment practices to continuously align the composition of the Board and its leadership structure with our long-term strategic needs. The Board, led by the Governance Committee, has an ongoing process for identifying, evaluating, and selecting directors, and these decisions are also informed by the annual Board and committee evaluation process described below. Our Governance Committee uses a variety of methods to help identify potential Board candidates and considers an assessment of current Board skills, background, diversity, independence, experience, tenure, and anticipated retirements to identify gaps that may need to be filled through the Board refreshment process.

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Current Board Composition: 7 new directors since 2015 3 women 2 ethnically/racially diverse directors Candidate Pool Sourced, Maintained and Updated Independent Search Firms Stockholders Independent Directors Select Directors Continuous Board Refreshment Governance Committee Review Review by the full Board Recommend Candidates to the Board Consider Guidelines for Director Qualifications and Evaluations (Appendix A) Consider skills matrix Include women and divers director candidates in the list from which director nominees are recommended Review independence and potential conflicts Meet candidates

Director Education

Our Board believes that director education is important to the ability of directors to fulfill their roles and supports Board members in their continuous learning. The Board encourages directors to participate in continuing education programs, and we reimburse directors for their expenses associated with this participation. During Board and committee meetings, education and information sessions are provided on specific subjects by internal and external experts. New directors also participate in our director orientation program.

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Regular Board and Committee Evaluations

Board and committee evaluations play a critical role in supporting the effective functioning of our Board. Through evaluations, our directors review where they believe our Board functions effectively and,

importantly, areas where our Board thinks there may be opportunities for improvement, including through Board refreshment.

Annual Governance Review

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Planning The Governance Committee oversees the Board evaluation process. In consultation with our lead independent director, and the committee Chairs, a framework for evaluation is established, including a review of topics for evaluation that are incorporated in the evaluation forms used by the Board and committees. Committee Evaluations and Assessment Formal annual anonymous evaluations of the Audit, Compensation, Compliance, and Governance Committees are collected, compiled, and distributed in advance of the scheduled discussion by each committee in executive session (typically in October). The evaluations include open-ended questions and space for candid commentary. All comments are unattributed, included verbatim, and shared with the full Board and each applicable committee. Each committee Chair reports out to the full Board on these assessments for review and discussion. One-on-One Discussions Our lead independent director conducts one-on-one discussions with each independent director. These candid conversations allow for direct and honest feedback on varied aspects of our Board's operations. Board Evaluation and Assessment Annual anonymous evaluations of the Board are collected, compiled, and distributed in advance of the scheduled discussion by the full Board in executive session (typically in December) and informed by the results of the committee-level evaluation discussions as well as the one-on-one discussions conducted by the lead independent director. Follow-Up Policies, practices, and the composition of our Board and its committees are modified, as appropriate, based on evaluation findings, one-on-one discussions, and follow-up items are discussed at subsequent Board and committee meetings. Ongoing Our directors are encouraged to convey ongoing feedback to our lead independent director or the Governance Committee during any executive session throughout the year.

Evaluation Results. The Audit, Compensation, Compliance, and Governance Committees each completed their committee evaluations and assessments in October 2021 and such evaluations were included as part of the total evaluation by the Governance Committee in December 2021. The Board completed its evaluation in December 2021. Each committee and the Board was considered to be operating effectively, with appropriate balance among governance, oversight, strategic, and operational matters, and each committee and the Board was satisfied with its performance.

Ongoing Feedback. Our directors provide real-time feedback throughout the year outside of the formal evaluation process and have

open access to management and third-party advisors. Additionally, executive sessions of directors (without management) are scheduled for every regular Board and committee meeting to identify any issues and assess whether meeting objectives were satisfied.

Changes Implemented. Based on the annual Board and committee evaluation process, ongoing feedback provided by directors, and one-on-one discussions between our lead independent director and each independent director, changes to Board practices have included enhancements to our committee structure and composition, additional presentations on various topics, and the addition of new directors.

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Corporate Governance

Director Independence

At least annually, the Governance Committee reviews the independence of each non-employee director and makes recommendations to the Board and the Board affirmatively determines whether each director qualifies as independent. Each director must keep the Governance Committee fully and promptly informed as to any development that may affect the director’s independence.

The Board has determined that each of our non-employee directors: Wanda M. Austin; Brian J. Druker; Robert A. Eckert; Greg C. Garland; Charles M. Holley, Jr.; S. Omar Ishrak; Tyler Jacks; Ellen J. Kullman; Amy E. Miles; Ronald D. Sugar; and R. Sanders Williams; and Fred Hassan (who served as a director during part of 2021) was independent during 2021 under The NASDAQ Stock Market listing standards and the requirements of the SEC. Mr. Bradway is not independent based on his service as our CEO and President. Mr. Bradway is the only director who also serves in a management capacity. In making its independence determinations, the Board reviewed direct and indirect transactions and relationships between each director or any member of his or her immediate family, and us or any of our subsidiaries or affiliates based on information provided by the director, our records, and/or publicly available information.

All of the reviewed transactions and arrangements were entered into in the ordinary course of business and none of the business transactions, donations, or grants involved an amount that (i) exceeded the greater of 5% of the recipient entity’s revenues or $200,000 with respect to transactions where a director or any member of his or her immediate family or spouse served as an employee, officer, partner, director, or controlling shareholder, or (ii) exceeded $10,000 with respect to professional or consulting services provided by entities at which directors serve as professors or employees.

The following types and categories of transactions, relationships, and arrangements were considered by our Board in making its independence determinations:

Each of the independent directors (or their immediate family members) currently serves or has previously served within the last

three years as a professor, trustee, director, or member of a board, advisory board, council, or committee for one or more colleges, universities, or non-profit charitable organizations, including research or scientific institutions, to which the Amgen Foundation has made grants or matching donations under the Amgen matching gift program that is available to all of our employees and directors.

Each of the independent directors (or their immediate family members) currently serves, or has previously served within the last three years, as a member of the board of directors, the board of trustees, or an advisory board for an entity with which Amgen has business transactions or to which Amgen or the Amgen Foundation makes donations or grants. These business transactions include, among other things, purchasing supplies, equipment and software licenses, payment of fees or memberships, and expenses relating to repair and maintenance, clinical trials, research and development and training, sponsorship of healthcare programs and conferences, financial advisory, investment management, investment advisory and consulting services, and reimbursement of business-related expenses incurred by our staff members (such as for transportation, gas, and food purchases).

Wanda M. Austin, Brian J. Druker, Tyler Jacks, and R. Sanders Williams currently serve as professors for universities to which Amgen has made payments for certain business transactions such as symposiums, conferences and exhibits, postdoctoral research programs, clinical trials, training and research and development, software licenses and maintenance, as well as for grants from the Amgen Foundation.

None of the directors, directly or indirectly, provides any professional or consulting services to us and none of the directors currently has or has had any direct or indirect material interest in any of the above transactions and arrangements. The Board determined that these transactions and arrangements did not warrant a determination that any of our directors were not independent.

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Corporate Governance

Governance Committee Processes and Procedures for Considering and Determining Director Compensation

The Governance Committee has the authority to evaluate and make recommendations to our Board regarding director compensation.

The Governance Committee conducts this evaluation periodically by reviewing our director compensation practices against the practices of an appropriate peer group and the Governance Committee has the authority to retain consultants to advise on director compensation matters, including in support of the Governance Committee’s periodic review of director compensation practices.

In 2020, the Governance Committee engaged Frederic W. Cook and Co., or FW Cook, to provide advice regarding director compensation.

FW Cook reported directly to the Governance Committee and attended the Governance Committee meeting to evaluate director compensation. No executive officer has any role in determining or recommending the form or amount of director compensation.

Based on the analysis provided by FW Cook, the Governance Committee determined to make changes to director compensation effective for 2021, the first increase since 2013, to align with market practice and attract and retain high-quality director candidates in a competitive global marketplace. For more information regarding director compensation, see “Director Compensation—2021 Director Compensation.

Audit Committee

Current Members:

Charles M. Holley, Jr.* (Chair)

Wanda M. Austin

Ellen J. Kullman*

Amy E. Miles*

*Audit Committee financial expert

Others who served in 2021:

Fred Hassan (until retirement at 2021 Annual Meeting)

Number of Meetings Held in 2021: 10

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC, including the requirements regarding financial literacy and sophistication.

Description and Key Responsibilities:

   Oversees our accounting and financial reporting process and the audits of the financial statements, as required by NASDAQ.

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the oversight of our financial accounting and reporting, the underlying internal controls and procedures over financial reporting, and the audits of the financial statements.

   Has sole authority for the appointment, compensation, and oversight of the work of the independent registered public accountants.

   Reviews and discusses, prior to filing or issuance, with management and the independent registered public accountants (when appropriate) our audited consolidated financial statements to be included in our Annual Report on Form 10-K and earnings press releases.

   Approves related party transactions.

   Reviews any violations or alleged violations of the Company’s Code of Ethics for the CEO and Senior Financial Officers.

Audit Committee Oversight of the Independent Registered Public Accountants

•   Auditor Selection. Evaluates the qualifications and performance of our independent registered public accountants each year and appoints the independent registered public accountants annually.

•   Audit Partner Selection. Participates directly in the selection of the lead engagement partner through an interview process.

•   Audit Firm Evaluation. Considers the quality and efficiency of the services provided, the independent registered public accountants’ technical expertise and knowledge of our operations and industry.

•   Audit Services. Pre-approves services.

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Corporate Governance

Corporate Responsibility and Compliance Committee

Current Members:

Ronald D. Sugar (Chair)

Brian J. Druker

S. Omar Ishrak (since July 30, 2021)

Tyler Jacks

R. Sanders Williams

Number of Meetings Held in 2021: 5

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

Description and Key Responsibilities:

   Oversees our compliance program and reviews our programs in a number of areas governing ethical conduct including:

-  U.S. federal health care program requirements;

-  U.S. Food and Drug Administration requirements and other regulatory agency requirements, including good manufacturing, clinical and laboratory practices, drug safety and pharmacovigilance activities;

-  interactions with members of the healthcare community;

-  the Company’s Corporate Integrity Agreement;

-  anti-bribery/anti-corruption risks;

-  environment, health, and safety;

-  information security, including cybersecurity; and

-  aspects of labor and employment activities and diversity, inclusion and belonging(1); and

-  government affairs, including the Political Action Committee.

   Receives regular updates on value (which includes pricing) and access, political, social, and environmental trends, and public policy issues that may affect our reputation, including our business or public image, and reviews our elements of our corporate responsibility (including environmental sustainability), political, and philanthropic activities.

About Our Compliance Program

Amgen’s Compliance Program is designed to promote ethical business conduct and compliance with applicable laws and regulations. The key objectives of our compliance program operations include:

Developing policies and procedures;

Providing ongoing compliance training and education;

Auditing and monitoring compliance risks;

Maintaining and promoting avenues for staff to raise concerns without fear of retaliation, including anonymously through a business conduct hotline;

Conducting investigations;

Responding appropriately to any compliance violations;

Taking appropriate steps to detect and prevent recurrence, including by implementing appropriate corrective and preventive actions; and

Promoting an ethical culture.

Our Chief Compliance Officer, who reports to the CEO and the Compliance Committee, oversees the ongoing operations of the compliance program.

(1)

Beginning in 2022, oversight of those aspects of labor and employment activities (including diversity, inclusion and belonging), previously overseen by the Compliance Committee, moved to the Compensation Committee.

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Corporate Governance

Our Approach to Environmental Sustainability, Social Responsibility, and Human Capital Management

Amgen’s ESG strategy begins with our mission to serve patients and is supported by our long-standing focus on using resources responsibly to support the sustainability of our business and the global environment in which we and our patients live.

ESG Oversight and Governance

ESG at Amgen is governed at the highest levels and includes Board and committee oversight, executive-level leadership, and subject-matter experts who lead our ESG efforts across our business.

Board Oversight. The Board and its applicable committees provide guidance and oversight to management with respect to ESG matters. The Compliance Committee assists the Board in overseeing our activities in areas that include environmental sustainability, diversity, inclusion and belonging, and access to medicines. Beginning in 2022, oversight of diversity, inclusion and belonging shifted to the Compensation Committee, the committee that also provides oversight of our approach to human capital management. The Governance Committee oversees the Company’s corporate governance activities and Board membership. Additionally, management shares feedback received from our stockholders with the Board, including in connection with our governance-focused engagement program. For additional discussion, please see “Positive 2021 Say on Pay Vote Outcome and Compensation Design Changes in Response to 2021 Stockholder Input” in our Compensation Discussion and Analysis.

Management Leadership. A cross-functional, executive-level governance council sets our overall ESG strategy, provides guidance on program implementation, and oversees the continuing enhancement of our approach to ESG. This council, chaired by our Senior Vice President, Corporate Affairs, regularly evaluates current and emerging ESG-related risk topics that are relevant to our business, including those considered as part of our ERM program. For additional information, please see “The Board’s Role in Risk Oversight” previously discussed.

Our ESG framework currently includes four strategic pillars—Healthy People, Healthy Society, Healthy Planet, and A Healthy Amgen—that serve as organizing principles facilitating our ability to address the interconnectivity of issues in a more holistic way across our business.

Amgen’s ESG Framework

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Program Implementation.Each pillar is supported by an initiative steering committee and, together with the oversight of our executive leadership, individual programmatic elements are managed at a business function level. Since 2021, to further integrate ESG across the organization, our Compensation Committee added an ESG goal to our Company performance goals for our annual cash incentive plan. For additional information, please see “Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance” in our Compensation Discussion and Analysis.

In addition to our history of strong corporate governance practices, examples of our ESG initiatives include our endeavors to strengthen science education and inspire the next generation of scientists, expand access to our medicines and support efforts to strengthen healthcare systems to better serve patients in need worldwide, and pursue a more environmentally sustainable business model. For additional information, please see “Board of Directors Corporate Governance Highlights” previously discussed.

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Corporate Governance

Environmental Sustainability

As a science-based company committed to advancing human health, Amgen recognizes the importance of climate change on human health around the world. We have a long-standing objective to conduct environmentally responsible operations and regularly set targets to challenge ourselves to deliver further improvements. Since 2007, we have successfully advanced our environmental sustainability program while substantially increasing our global production capacity and patient reach.

Building on the successful execution of our 2013-2020 conservation targets, we launched a new environmental sustainability plan in 2021 (our third since 2007) that includes a target of achieving carbon neutrality in our operations by 2027, while also aiming to further reduce our water use (by 40%) and waste disposed (by 75%).(1)

LOGO

Our 2027 Environmental Sustainability Plan. To achieve our 2027 goals, we plan to harness our innovative capabilities to help combat climate change and preserve natural resources. We expect these efforts to help us become not just more environmentally sustainable but also more flexible and productive, resulting in reductions in operating costs from such efficiencies over the same period.

Our 2027 plan is designed to drive specific environmental sustainability projects across our operations, including continued investment in highly resource efficient biomanufacturing, smart and integrated facility design, use of on-site solar and other renewable energy sources, electric vehicle fleet conversion, treatment and reuse of water, the reduction and recycling of single-use plastics, and the reduction of consumables packaging. This plan also includes activities to further integrate the potential risks and opportunities from climate change into our existing processes for strategic planning, analysis, and risk management.

The Road to Net Zero. To help achieve our goal of carbon neutrality by 2027(1), Amgen is focusing on the use of innovative technologies and efficiency projects to reduce carbon emissions from our owned and operated facilities, in addition to sourcing renewable energy. Where renewable sources are not available, we expect to prioritize offsetting based on the quality of the credit or offset.

Sustainability by Design. Amgen helped to invent the processes and tools that created the global biotech industry. As we continue to grow

and innovate, we are pioneering advanced technologies and implementing more environmentally responsible approaches throughout the Company to increase operational efficiency and reduce our environmental footprint.

Our next-generation biomanufacturing facility in Singapore, which began commercial production in 2017, is an example of our innovative capability at work. This redesign of our approach to biomanufacturing dramatically reduces the scale and costs of making biologic medicines, and vastly reduces water and energy use, while maintaining a reliable, high-quality, compliant supply of medicines.

LOGO

The success of our facility in Singapore, along with U.S. corporation tax incentives to invest in innovation and advanced technologies, led to our building a second such plant in the U.S. in Rhode Island. This facility was licensed by the U.S. Food and Drug Administration in January 2022 and will support product volume growth, while delivering environmental and operating efficiencies.

We continue to apply innovation to our facilities with multiple ongoing projects, including in connection with the expansion of our U.S. plants. In 2021, we commenced construction on two new facilities (a final product assembly and packaging plant in Ohio and a multi-product drug substance facility in North Carolina). These facilities are expected to support our ability to meet the demand for our medicines, utilize cutting-edge technologies to be more efficient and environmentally friendly than traditional plants, and bring hundreds of full-time jobs to the regions while expanding our access to diverse talent.

(1)

Carbon neutrality goal refers to Scope 1 and 2. Reductions take into account only verified reduction projections, do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

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Corporate Governance

Sustainable Value Chain. Our footprint and focus on sustainability extend beyond our own employees and facilities. Amgen’s 2027 environmental sustainability plan includes engaging with our suppliers and contactors to evaluate the carbon impact throughout our value chain and identify reduction opportunities.

ESG Reporting.Informed by insights from our investors, we enhanced our ESG reporting in 2021 by expanding our latest Environmental, Social, and Governance Report by mapping our reporting to the Sustainability Accounting Standards Board (SASB) standards for our industry, disclosing our annual Consolidated EEO-1 Report, and providing additional metrics on the diversity of our workforce.

Since 2010, Amgen has reported to CDP (formally the Carbon Disclosure Project). Over time, CDP’s disclosure platform for climate change has evolved to contain over 25 questions (within its governance, risks and opportunities, strategy, targets and emissions modules) that are aligned with the recommendations of the Task Force on Climate-related Financial Disclosures, or TCFD; this platform is now nearly in full alignment with the TCFD. We continue to report to the CDP as completely as possible and, in 2022, we are undertaking a TCFD-aligned scenario analysis to improve our understanding of the physical and transitional effects of climate change as well as inform our future reporting.

United Nations Global Compact. We are a signatory to the United Nations Global Compact, a voluntary initiative based on commitments to implement universal sustainability principles and take steps to support the United Nations Sustainable Development Goals.

Social Responsibility

Improving Patient Access to Medicines. Through patient assistance programs, expanded access to investigational therapies, donations, and other initiatives, Amgen has developed support programs for eligible patients around the world as they seek to obtain the medicines they need.

Amgen Safety Net Foundation (ASNF), a separate legal entity entirely funded by Amgen, supports qualifying patients in the U.S. who might go without important medicines because of financial limitations, by providing our medicines at no cost. In 2021, the commercial value of Amgen’s medicines provided at no cost to uninsured or underinsured patients by ASNF was over $2 billion.(1)

Since 2018, Amgen has also donated approximately $140 million worth of Amgen cancer treatment and supportive care medicines(1) for distribution to patients in more than 30 developing countries through Direct Relief, a leading non-governmental organization.

We continue to offer and implement value-based contracts in an effort to help improve patient access to medicines and offer stakeholders greater budget predictability.

Advancing Health Equity. As part of our mission to serve patients, we are working to improve the diversity and representation of racial and ethnic minority populations in clinical trial research at Amgen and to advance solutions and increase dialogue regarding this area across the industry.

We recognize the importance of a patient-centric approach to clinical research and our Representation in Clinical Research (RISE) team is working with groups within Amgen and outside of the business towards exceeding industry standards for clinical trial diversity and representation and helping Amgen develop new medicines studied in participants who better reflect the populations affected by certain diseases or conditions. We also continue building relationships with leaders and organizations in diverse communities to help address healthcare disparities, improve disease state awareness, and increase dialogue in this area.

Supplier Diversity and Responsible Sourcing. We aspire to double our supplier diversity spend, and triple our Black-owned business spend, in the U.S. by 2023.(2) Our supplier diversity program is designed to achieveidentify, develop, and utilize small, disadvantaged, veteran, LGBTQ, minority, disabled, and women-owned business enterprises, as well as companies located in historically underutilized business zones, in our procurement of goods and services. Our efforts include mentoring and development opportunities to further strengthen the following objectives:leadership capabilities of these diverse suppliers and contactors.

All staff members are guided by the Amgen Values and global Code of Conduct and, similarly, we request our suppliers to conduct their businesses in alignment with our mission and values. Our supplier sustainability program focuses not only on quality, cost, and reliability but also on a wide range of sustainability and social responsibility considerations, such as business ethics, labor and human rights, and environmental impacts.

Science Education. The Amgen Foundation seeks to advance excellence in science education to inspire the next generation of innovators and invest in strengthening communities where our staff members live and work.

Since its inception over 30 years ago, the Amgen Foundation has contributed more than $375 million to non-profit organizations around the world that reflect our core values and complement Amgen’s dedication to impacting lives in inspiring and innovative ways.

 

Pay for performanceLabXchange, developed at Harvard University with the financial support of the Amgen Foundation, is a free online science education platform that provides students around the world with access to personalized instruction, virtual lab experiences, and networking opportunities across the global scientific community. In 2021, with the Amgen Foundation’s support, LabXchange launched a digital curriculum focused on examining racial inequity in a manner that strongly aligns with stockholder interests by rewarding both our short-healthcare, education, and long-term measurable performance.

Drive our business strategy by positioning our staff to execute on our strategic prioritiesSTEM fields in the near- and longer-term.U.S.

 

Attract, motivate,The Amgen Foundation is the exclusive biology content partner of Khan Academy, a leading online learning platform, and retain the highest level of talent by providing competitive compensation, consistent with their roles and responsibilities, our success, and their contributions to this success.

Mitigate compensation riskby maintaining pay practices that reward actions and outcomes consistent with the sound operation of our Company and with the creation of long-term stockholder value.

Consider all Amgen staff members in the design of our executive compensation programs, to ensure a consistent approach that encourages and rewards all staff members who contribute to our success.approximately

 

 

(1)

Valued at wholesale acquisition cost.

(2)

Measured against a 2019 baseline.

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Corporate Governance

15 million users accessed Khan Academy’s free biology lessons in 2021. Through an expanded, multi-year partnership with the Amgen Foundation in support of science learning and education equity, Khan Academy is creating a comprehensive offering of biology resources for students and teachers worldwide and expanding its partnerships with school districts facing budget shortfalls.

Additionally, the Amgen Foundation continued to expand the Amgen Biotech Experience (ABE), an innovative science education program that empowers high school teachers to bring biotechnology education into their classrooms. In 2021, the second cohort of the ABE Master Teacher Fellowship was announced with twelve fellows from around the globe who each receive a stipend and targeted support to develop a curriculum project to be shared with the ABE international community.

The Amgen Scholars Program makes it possible for undergraduates around the globe to engage in cutting-edge research experiences in leading graduate laboratories and learn more about biotechnology and drug discovery.

Our Community. In 2021, The Amgen Foundation provided grants totaling $3 million to more than 30 U.S.-based nonprofits in support of racial and social justice initiatives, economic empowerment, and equal opportunity in education.

Amgen and the Amgen Foundation have been engaged with our community during the pandemic. For additional information, please see “Responding to COVID-19” previously discussed.

The Amgen Foundation also provides programs and resources to empower individual Amgen staff in their charitable activities in our community, including through a matching gift program and by providing service grants to non-profit organizations where staff members regularly volunteer.

We Have Implemented Compensation Best Practices

 

 

What we do

 

A substantial majority of NEO compensation is performance based andat-risk

Recoupment in the case of misconduct causing serious financial or reputational damage

Clawback policy tied to financial restatement

Robust stock ownership and retention guidelines

Minimum vesting periods for equity compensation

 

 

Long-term performance-based equity awards (80% of total target equity)equity, of which 50% are three-year performance unit awards and 30% are stock options)

A substantial majority of NEO compensation is performance-based and at-risk

Recoupment provisions for misconduct that causes serious financial or reputational damage include forfeiture and cancellation of unvested or unexercised(1) equity awards and annual cash incentive awards being deemed not earned in full or part

Clawback policy tied to financial restatement and misconduct that permits recapture of past cash or long-term incentive equity award payouts

Robust stock ownership (6x for Chief Executive Officer) and retention guidelines

Minimum vesting periods of one year, with most equity grants vesting over four years (with no vesting in the first year and vesting in three approximately equal installments thereafter)

We use market median values as the reference point for each element of compensation at all job levels, including our NEOs

 

 

Independent compensation consultant

Amgen Values overlay our performance goals

 

What we don’t do

 

 

×

No alterations to our established goals to respond to changing business conditions (for example, we have not made any changes to established goals in response to the occurrence or challenges of the pandemic)

×

  

No hedging or pledging

×

  

Nore-pricing or backdating

×

  

No taxgross-ups (except in connection with relocation)

×

  

No single-trigger for stock options and restricted stock units in the event of a change of control

×

  

No excessive perks

×

  

No employment agreements

×

  

No dividends paid on unvested equity

×

  

No defined benefit pension or supplemental executive retirement plan (SERP) benefits

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPROVAL OF THE

ADVISORY RESOLUTION TO APPROVE THE COMPENSATION OF THE

COMPANY’S NAMED EXECUTIVE OFFICERS.

(1)

Forfeiture and cancellation applies to any unvested or unexercised portion of any stock options granted after December 31, 2020.

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Proxy Statement Summary

Item 3: Ratification of Selection of Independent Registered Public Accountants (Page 94)

Each year, the Audit Committee evaluates the qualifications and performance of the Company’s independent registered public accountants and determines whether to re-engage the current independent registered public accountants.

Based on this evaluation, the Audit Committee believes that the continued retention of Ernst & Young LLP, or EY, is in the best interests of the Company and its stockholders.

The Audit Committee of the Board has selected EY as our independent registered public accountants for the fiscal year ending December 31, 2022.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” RATIFICATION OF OUR

INDEPENDENT REGISTERED PUBLIC ACCOUNTANTS.

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Item 1 — Election of Directors

Item 1

Election of Directors

Under our governance documents, the Board of Directors, or Board, has the power to set the number of directors from time to time by resolution. The Board has fixed the authorized number of directors at 12 and we currently have 12 directors serving on our Board. Our Board is composed of directors with a wide range of relevant experiences and backgrounds and considers a number of attributes when seeking new candidates for the Board as discussed more fully below and in the section “Corporate Governance—Process for Selecting Directors, Director Qualifications, and Board Diversity.” Based upon the recommendation of our Governance and Nominating Committee, or Governance Committee, the Board has nominated each of the director nominees set forth below to stand for election as a director, in each case for a one-year term expiring at our 2023 annual meeting of stockholders and until his or her successor is elected and qualified, or until his or her earlier retirement, resignation, disqualification, removal, or death.

Each nominee has agreed to serve if elected and the Board has no reason to believe that any nominee will be unable to serve. However, if

any nominee should become unavailable for election prior to the 2022 Annual Meeting of Stockholders, or Annual Meeting, proxies will be voted in favor of the election of a substitute nominee or nominees proposed by the Board or, alternatively, the number of directors may be reduced accordingly by the Board. Vacancies on the Board (including any vacancy created by an increase in the size of the Board) may be filled only by a majority of the directors remaining in office, even if less than a quorum of the Board. A director elected by the Board to fill a vacancy (including a vacancy created by an increase in the size of the Board) will serve until the next annual meeting of stockholders and until such director’s successor is elected and qualified, or until such director’s earlier retirement, resignation, disqualification, removal, or death.

The independent members of the Board have elected Robert A. Eckert to continue to serve as our lead independent director, subject to his re-election to the Board by our stockholders at the Annual Meeting. As lead independent director, Mr. Eckert will continue to have the specific and significant duties as discussed under “Corporate Governance.”

Nominees to the Board

  

Nominee

   Independent    Age    

Director

Since

 

 

   Audit    

Governance

and

Nominating

 

 

 

   Executive   

 

 

 

Compensation

and

Management

Development

 

 

 

 

 

   

Equity

Award

 

 

   

Corporate  

Responsibility  

and  

Compliance  

 

 

 

 

 

Wanda M. Austin

  

 

 

  

 

67

 

  

 

2017

 

  

 

M

 

      

 

M

 

    
 

Robert A. Bradway

    

 

59

 

  

 

2011

 

      

 

C

 

    

 

M

 

  
 

Brian J. Druker

  

 

 

  

 

66

 

  

 

2018

 

        

 

M

 

    

 

M

 

 

Robert A. Eckert*

  

 

 

  

 

67

 

  

 

2012

 

    

 

M

 

  

 

M

 

  

 

C

 

    
 

Greg C. Garland

  

 

 

  

 

64

 

  

 

2013

 

    

 

C

 

  

 

M

 

  

 

M

 

    
 

Charles M. Holley, Jr.

  

 

 

  

 

65

 

  

 

2017

 

  

 

C

 

  

 

M

 

  

 

M

 

      
 

S. Omar Ishrak

  

 

 

  

 

66

 

  

 

2021

 

        

 

M

 

    

 

M

 

 

Tyler Jacks

  

 

 

  

 

61

 

  

 

2012

 

        

 

M

 

    

 

M

 

 

Ellen J. Kullman

  

 

 

  

 

66

 

  

 

2016

 

  

 

M

 

  

 

M

 

        
 

Amy E. Miles

  

 

 

  

 

55

 

  

 

2020

 

  

 

M

 

  

 

M

 

        
 

Ronald D. Sugar

  

 

 

  

 

73

 

  

 

2010

 

    

 

M

 

  

 

M

 

      

 

C

 

  

R. Sanders Williams

  

 

 

  

 

73

 

  

 

2014

 

       

 

M

 

                 

 

M

 

“*”

indicates Lead Independent Director.

“C”

indicates Chair of the committee.

“M”

indicates member of the committee.

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Item 1 — Election of Directors

Summary of Director Nominee Core Experiences and Skills

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, have gained significant and wide-ranging management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees), an understanding of corporate governance practices and trends, and bring unique perspectives to the Board. A number of our directors have extensive scientific and healthcare expertise relevant to our industry, including pioneering scientific research in the areas of oncology and cardiology and experience leading important academic institutions. The Board and the Governance Committee believe the skills, qualities, attributes, experience and diversity of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director nominee. The details of each nominee’s competencies are included in each nominee’s biography.

LOGO

Experience/Skills Austin Bradway Druker Eckert Garland Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

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Item 1 — Election of Directors

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE NAMED NOMINEES. PROXIES WILL BE VOTED “FOR” THE ELECTION OF THE NOMINEES UNLESS OTHERWISE SPECIFIED.

Set forth below is biographical information for each nominee and a summary of the specific qualifications, attributes, skills, and experiences which led our Board to conclude that each nominee should serve on the Board at this time. All of our directors meet the qualifications and skills of our Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations included in this proxy statement as Appendix A. There are no family relationships among any of our directors or among any of our directors and our executive officers.

Wanda M. Austin

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Director since: 2017

Age:67

Committees:

  Audit

  Compensation and Management Development

Other Public Company Boards:

  Chevron Corporation

  Virgin Galactic Holdings, Inc.

Wanda M. Austin is the retired President and Chief Executive Officer of The Aerospace Corporation, a leading architect of the United States’ national security space programs, where she served from 2008 until her retirement in 2016. From 2004 to 2007, Dr. Austin was Senior Vice President, National Systems Group of The Aerospace Corporation. Dr. Austin joined The Aerospace Corporation in 1979 and served in various positions from 1979 until 2004.

Dr. Austin was the Interim President of the University of Southern California, or USC, from 2018 to 2019 and has served as an Adjunct Research Professor at USC’s Viterbi School of Engineering since 2007. She is the co-founder of MakingSpace, Inc., where she serves as a motivational speaker on STEM education. Dr. Austin has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2016, serving on its Management Compensation Committee and chairing its Board Nominating and Governance Committee. Dr. Austin has been a director of Virgin Galactic Holdings, Inc., a commercial space flight company, since 2019 and is a member of its Safety Committee, and Chair of its Compensation Committee. Dr. Austin is a life trustee of USC, having served as a voting trustee from 2010 to March 2021, and previously served on the boards of directors of the National Geographic Society and the Space Foundation. Dr. Austin received an undergraduate degree from Franklin & Marshall College, a master’s degree from the University of Pittsburgh, and a doctorate from USC. She is a member of the National Academy of Engineering.

Qualifications

The Board concluded that Dr. Austin should serve on the Board based on her leadership and management experience as a chief executive officer, her extensive background in science, technology, and government affairs in a highly regulated industry, and her public board experience.

Robert A. Bradway

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Director since:2011

Age:59

Committees:

  Equity Award

  Executive (Chair)

Other Public Company Boards:

  The Boeing Company

Robert A. Bradway has served as our director since 2011 and Chairman of the Board since 2013. Mr. Bradway has been our President since 2010 and Chief Executive Officer since 2012. From 2010 to 2012, Mr. Bradway served as our Chief Operating Officer. Mr. Bradway joined Amgen in 2006 as Vice President, Operations Strategy and served as Executive Vice President and Chief Financial Officer from 2007 to 2010. Prior to joining Amgen, he was a Managing Director at Morgan Stanley in London where, beginning in 2001, he had responsibility for the firm’s banking department and corporate finance activities in Europe.

Mr. Bradway has been a director of The Boeing Company, an aerospace company and manufacturer of commercial airplanes, defense, space and securities systems, since 2016, serving as the Chair of the Finance Committee and a member of the Governance and Public Policy Committee. From 2011 to 2017, Mr. Bradway was a director of Norfolk Southern Corporation, a transportation company. He has served on the board of trustees of the University of Southern California since 2014. Mr. Bradway holds a bachelor’s degree in biology from Amherst College and a master’s degree in business administration from Harvard Business School.

Qualifications

The Board concluded that Mr. Bradway should serve on the Board based on his thorough knowledge of all aspects of our business, combined with his leadership and management skills having previously served as our President and Chief Operating Officer and as our Chief Financial Officer.

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Item 1 — Election of Directors

Brian J. Druker

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Director since:2018

Age:66

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Vincerx Pharma, Inc.

Brian J. Druker joined Oregon Health & Science University, or OHSU, in 1993 and is currently a physician-scientist and professor of medicine. Dr. Druker has served as the director of the OHSU Knight Cancer Institute since 2007, associate dean for oncology of the OHSU School of Medicine since 2010, and the JELD-WEN chair of leukemia research at OHSU since 2001. He was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, from 2002 to 2019.

Dr. Druker has been a director of Vincerx Pharma, Inc., a biopharmaceutical company, since December 2020, and serves on its Nominating and Corporate Governance Committee. Dr. Druker has served on the scientific advisory board of Aptose Biosciences Inc., a biotechnology company, since 2013. Dr. Druker has been a consultant to Grail, Inc., a biotechnology company, since 2021, and served on its scientific advisory board, from 2016 to 2019. In 2011, he founded Blueprint Medicines Corporation, a biopharmaceutical company, and remains as a scientific advisor to this company. In 2006, he founded MolecularMD, a privately-held molecular diagnostics company that was acquired by ICON plc in 2019.

Dr. Druker has received numerous awards, including the Lasker-DeBakey Clinical Research Award in 2009, the Japan Prize in Healthcare and Medical Technology in 2012, the Albany Medical Center Prize in 2013, and the Sjöberg Prize in 2019, for influential work in the development of STI571 (Gleevec®) for the treatment of chronic myeloid leukemia. He was elected to the National Academy of Sciences in 2012 as well as the National Academy of Medicine in 2007. Dr. Druker received both an undergraduate degree and his medical doctorate from the University of California, San Diego.

Qualifications

The Board concluded that Dr. Druker should serve on the Board based on his extensive scientific research and expertise leading an important academic institution, conducting highly significant research in the area of oncology, and directly managing the care of cancer patients.

Robert A. Eckert

Lead Independent Director

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Director since:2012

Age:67

Committees:

  Compensation and Management Development (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Levi Strauss & Co.

  McDonald’s Corporation

  Uber Technologies, Inc.

Robert A. Eckert is our lead independent director. Mr. Eckert has been an Operating Partner at FFL Partners, LLC (formerly known as Friedman Fleischer & Lowe, LLP), a private equity firm, since 2014. Mr. Eckert was the Chief Executive Officer of Mattel, Inc., a toy design, manufacture and marketing company, having held this position from 2000 through 2011, and its Chairman of the Board from 2000 through 2012. He was President and Chief Executive Officer of Kraft Foods Inc., a consumer packaged food and beverage company, from 1997 to 2000, Group Vice President from 1995 to 1997, President of the Oscar Mayer Foods Division from 1993 to 1995 and held various other senior executive and other positions from 1977 to 1992.

Mr. Eckert has been a director of McDonald’s Corporation, a company that franchises and operates McDonald’s restaurants in the global restaurant industry, since 2003, serving as the Chair of the Public Policy and Strategy Committee and a member of the Executive and Governance Committees. Mr. Eckert also has served as a director of Levi Strauss & Co., a jeans and casual wear manufacturer, since 2010, serving as Chair of the Nominating, Governance and Corporate Citizenship Committee and a member of the Compensation Committee and, since March 2021, as non-executive Chair of the board. In 2020, Mr. Eckert was appointed a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, serving as Chair of the Compensation Committee and a member of the Nominating and Governance Committee. Mr. Eckert was a director of Smart & Final Stores, Inc., a warehouse store, from 2013 until 2014 prior to it becoming a publicly-traded company. He was appointed director of Eyemart Express Holdings LLC, a privately-held eyewear retailer and portfolio company of FFL Partners, LLC, in 2015. Mr. Eckert is on the Global Advisory Board of the Kellogg School of Management at Northwestern University and serves on the Eller College National Board of Advisors at the University of Arizona. Mr. Eckert received an undergraduate degree from the University of Arizona and a master’s degree in business administration from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Mr. Eckert should serve on our Board because of Mr. Eckert’s long-tenured experience as a chief executive officer and director of large public companies, his broad international experience in marketing and business development, and his valuable leadership experience.

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Item 1 — Election of Directors

Greg C. Garland              

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Director since:2013

Age:64

Committees:

  Compensation and Management Development

  Executive

  Governance and Nominating (Chair)

Other Public Company Boards:

  Phillips 66(1)

Greg C. Garland is the Chairman and Chief Executive Officer of Phillips 66, a diversified energy manufacturing and logistics company created through the repositioning of ConocoPhillips, having held this position since 2012. Mr. Garland chairs the Executive Committee of Phillips 66.(1) Prior to Phillips 66, Mr. Garland served as Senior Vice President, Exploration and Production, Americas of ConocoPhillips from 2010 to 2012. He was President and Chief Executive Officer of Chevron Phillips Chemical Company (now a joint venture between Phillips 66 and Chevron) from 2008 to 2010 and Senior Vice President, Planning and Specialty Chemicals from 2000 to 2008. Mr. Garland served in various positions at Phillips Petroleum Company from 1980 to 2000. Mr. Garland is a member of the Engineering Advisory Council for Texas A&M University. Mr. Garland received an undergraduate degree from Texas A&M University.

Qualifications

The Board concluded that Mr. Garland should serve on our Board because of Mr. Garland’s experience as a chief executive officer and his over 30 years of international experience in a highly regulated industry.

(1)

Mr. Garland served as Chairman and Chief Executive Officer of Phillips 66 Partners LP, a master limited partnership and subsidiary of Phillips 66 without any employees, until its full acquisition in March 2022 by Phillips 66.

Charles M. Holley, Jr.      

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Director since:2017

Age:65

Committees:

  Audit (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Carrier Global Corporation

  Phillips 66

Audit Committee financial expert

Charles M. Holley, Jr. is the former Executive Vice President and Chief Financial Officer for Wal-Mart Stores, Inc., or Walmart, where he served from 2010 to 2015 and as Executive Vice President in January 2016. Prior to this, Mr. Holley served as Executive Vice President, Finance and Treasurer of Walmart from 2007 to 2010. From 2005 to 2006, he served as Senior Vice President. Prior to that, Mr. Holley was Senior Vice President and Controller from 2003 to 2005. Mr. Holley served various roles in Wal-Mart International from 1994 through 2002. Prior to this, Mr. Holley served in various roles at Tandy Corporation. He spent more than ten years with Ernst & Young LLP. Mr. Holley was an Independent Senior Advisor, U.S. CFO Program, at Deloitte LLP, a privately-held provider of audit, consulting, tax, and advisory services, from 2016 to 2019.

Mr. Holley has been a director of Phillips 66 since 2019 and serves on the Audit and Finance, and Public Policy and Sustainability Committees. Mr. Holley has also been a director of Carrier Global Corporation, a provider of heating, ventilating, air conditioning (HVAC), refrigeration, fire, and security solutions, since 2020 and chairs the Audit Committee and serves as a member of the Compensation Committee. Mr. Holley serves on the Advisory Council for the McCombs School of Business at the University of Texas at Austin and the University of Texas Presidents’ Development Board.

Qualifications

The Board concluded that Mr. Holley should serve on the Board based on his experience as a chief financial officer of a global public company, his financial acumen, and his management and leadership skills. Given his financial and leadership experience, Mr. Holley has been determined to be an Audit Committee financial expert by our Board.

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Item 1 — Election of Directors

S. Omar Ishrak

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Director since:2021

Age:66

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Intel Corporation

  Compute Health Acquisition Corporation

S. Omar Ishrak has served as a director of the Company since July 2021. Dr. Ishrak was first identified to the Governance and Nominating Committee as a potential director candidate by the Chairman and certain non-employee members of the Board, including our lead independent director. He is the former Executive Chairman and Chairman of the Board of Directors of Medtronic plc, or Medtronic, a global medical technology company. Dr. Ishrak served as the Chief Executive Officer of Medtronic from 2011 to April 2020 and was Executive Chairman until December 2020. Prior to joining Medtronic, he served as President and Chief Executive Officer of GE Healthcare Systems, a provider of medical imaging and diagnostic technology and a division of GE Healthcare, from 2009 to 2011. Dr. Ishrak was President and Chief Executive Officer of GE Healthcare Clinical Systems from 2005 to 2008 and President and Chief Executive Officer of GE Healthcare Ultrasound and BMD from 1995 to 2004.

Dr. Ishrak has been a director of Intel Corporation, a multinational corporation and technology company, since 2017 and Chairman of its Board since 2020, serving as a member of the Compensation Committee and Corporate Governance and Nominating Committee. He has served as Chairman of the Board of Directors of Compute Health Acquisition Corporation, a special purpose acquisition company, since 2021. Dr. Ishrak is a member of the Board of Trustees of the Asia Society, an educational organization dedicated to promoting mutual understanding and strong partnerships between Asia and the U.S. Since 2021, Dr. Ishrak has been a senior advisor to Blackstone Life Sciences, a segment of Blackstone Inc. that invests in the biopharmaceutical and medical technology industries.

Dr. Ishrak was inducted into the American Institute for Medical and Biological Engineering College of Fellows in 2016, elected as a Fellow of King’s College London in 2017, inducted into the Bakken Society in 2020, and elected to the National Academy of Engineering in 2020. Dr. Ishrak received his undergraduate degree and doctorate from the University of London, King’s College.

Qualifications

The Board concluded that Dr. Ishrak should serve on our Board based on Dr. Ishrak’s board and senior executive-level expertise, including his experience as chief executive officer of a global, highly regulated public company in the healthcare industry, his extensive background in medical technologies, manufacturing, international expertise and interest in Asia, and his management and leadership skills.

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Item 1 — Election of Directors

Tyler Jacks

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Director since:2012

Age:61

Committees:

  Compensation and Management Development

  Corporate Responsibility and Compliance

Other Public Company Boards:

  Thermo Fisher Scientific, Inc.

Tyler Jacks joined the faculty of Massachusetts Institute of Technology, or MIT, in 1992 and is currently the David H. Koch Professor of Biology, a position he has held since 2007, and founding director of the David H. Koch Institute for Integrative Cancer Research, which brings together biologists and engineers to improve detection, diagnosis and treatment of cancer, having served as director from 2007 to 2021. Since 2021, Dr. Jacks has served as President and director of Break Through Cancer, a foundation bringing together multidisciplinary cancer research teams selected from across five participating institutions.(1) Dr. Jacks was an investigator with the Howard Hughes Medical Institute, a nonprofit medical research organization, from 1994 until 2021.

Dr. Jacks has been a director of Thermo Fisher Scientific, Inc., a life sciences supply company, since 2009, serving as the Chair of its Science and Technology Committee and as a member of its Strategy and Finance Committee and its scientific advisory board. In 2006, he co-founded T2 Biosystems, Inc., a biotechnology company, and served on its scientific advisory board until 2013. Dr. Jacks has served on the scientific advisory board of SQZ Biotechnologies Company, a biotechnology company, since 2015. Dr. Jacks served on the scientific advisory board of Aveo Pharmaceuticals Inc., a biopharmaceutical company, from 2001 until 2013. In 2015, Dr. Jacks founded Dragonfly Therapeutics, Inc., a privately-held biopharmaceutical company, and serves as Chair of its scientific advisory board. In 2011, he was appointed to the National Cancer Advisory Board, which advises and assists the Director of the National Cancer Institute with respect to the National Cancer Program, and served as Chair until 2016. In 2016, Dr. Jacks was named to a blue ribbon panel of scientists and advisors established as a working group of the National Cancer Advisory Board and served as co-Chair advising the Cancer MoonshotSM Task Force. Dr. Jacks was a director of MIT’s Center for Cancer Research from 2001 to 2007 and received numerous awards including the Paul Marks Prize for Cancer Research and the American Association for Cancer Research Award for Outstanding Achievement. He was elected to the National Academy of Sciences as well as the National Academy of Medicine in 2009 and received the MIT Killian Faculty Achievement Award in 2015. Dr. Jacks received an undergraduate degree from Harvard University and his doctorate from the University of California, San Francisco.

Qualifications

The Board concluded that Dr. Jacks should serve on the Board based on his extensive scientific expertise relevant to our industry, including his broad experience as a cancer researcher, pioneering uses of technology to study cancer-associated genes, and service on several scientific advisory boards and service to the National Cancer Advisory Board.

(1)

Dana-Farber Cancer Institute, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The University of Texas MD Anderson Cancer Center, Memorial Sloan Kettering Cancer Center, and the Koch Institute for Integrative Cancer Research at MIT.

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Item 1 — Election of Directors

Ellen J. Kullman

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Director since: 2016

Age:66

Committees:

  Audit

  Governance and Nominating

Other Public Company Boards:

  Dell Technologies Inc.

  Goldman Sachs Group, Inc.

Audit Committee financial expert

Ellen J. Kullman is President and Chief Executive Officer of Carbon, Inc., or Carbon, a privately-held 3D printing company, having held this position since 2019, and has served as a director of Carbon since 2016. She is the former President, Chair and Chief Executive Officer of E.I. du Pont de Nemours and Company, or DuPont, a science and technology-based company, where she served from 2009 to 2015. Prior to this, Ms. Kullman served as President of DuPont from 2008 to 2009. From 2006 through 2008, she served as Executive Vice President of DuPont. Prior to that, Ms. Kullman was Group Vice President, DuPont Safety and Protection. Ms. Kullman has been a director of Goldman Sachs Group, Inc., an investment banking firm, since 2016, serving on its Compensation and Corporate Governance and Nominating Committees and chairing its Public Responsibilities Committee. Ms. Kullman has been a director of Dell Technologies Inc., a technology company, since 2016, serving on its Audit Committee. Ms. Kullman served as a director of United Technologies Corporation, a technology products and services company, from 2011 (and as lead director from 2018), serving on its Compensation, Finance and Executive Committees, until its merger with Raytheon Company in 2020. Ms. Kullman served as a director of General Motors, from 2004 to 2008, serving on its Audit Committee.

Ms. Kullman has served on the Board of Trustees of Northwestern University since 2016 and is a Trustee Emerita of Tufts University School of Engineering, having served on its Board of Advisors since 2006. She served as Chair of the US-China Business Council from 2013 to 2015. Since 2016, Ms. Kullman has been a member of the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Ms. Kullman received a bachelor of science in mechanical engineering degree from Tufts University and a master’s degree from the Kellogg School of Management at Northwestern University.

Qualifications

The Board concluded that Ms. Kullman should serve on the Board based on her lengthy global experience as chief executive officer and board chair at both public and private companies, her management and leadership skills, and her experience with scientific operations, all of which provide valuable insight into the operations of our Company. Given her leadership and financial experience, Ms. Kullman has been determined to be an Audit Committee financial expert by our Board.

Amy E. Miles

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Director since: 2020

Age:55

Committees:

  Audit

  Governance and Nominating

Other Public Company Boards:

  Gap Inc.

  Norfolk Southern Corporation

Audit Committee financial expert

Amy E. Miles was the Chief Executive Officer and a director of Regal Entertainment Group, Inc., or Regal Entertainment, a leading theatre exhibition company, having held these positions from 2009 through 2018, and its Chair of the Board from 2015 to 2018. From 2002 to 2009, Ms. Miles served as Executive Vice President, Chief Financial Officer and Treasurer of Regal Entertainment. Ms. Miles also served as Chief Executive Officer of Regal Cinemas, Inc., or Regal Cinemas, from 2009 to 2018, and its Executive Vice President, Chief Financial Officer and Treasurer from 2000 to 2009. Ms. Miles joined Regal Cinemas in 1999 as Senior Vice President of Finance. Previously, Ms. Miles was with Deloitte & Touche, LLP and PricewaterhouseCoopers LLP.

Ms. Miles has been a director of Norfolk Southern Corporation, a transportation company, since 2014, and serves on the Executive Committee, the Governance and Nominating Committee, and chairs the Audit Committee, and, beginning in May 2022, will serve as non-executive Chair of the board and cease serving as Chair of the Audit Committee, but will remain a member of the Audit Committee. Ms. Miles has been a director of The Gap, Inc., an apparel retail company, since 2020, and chairs the Audit and Finance Committee. Ms. Miles was a director of National CineMedia, Inc., a cinema advertising company, from 2011 to 2015. She was a director of Townsquare Media, Inc., a radio, digital media, entertainment, and digital marketing solutions company, from 2014 until 2016.

Ms. Miles has been a director of ASM Global, a privately-held entertainment and venue management company, since 2019. Ms. Miles serves on the boards of trustees of the University of Tennessee and the Boys and Girls Club of Eastern Tennessee.

Qualifications

The Board concluded that Ms. Miles should serve on our Board based on Ms. Miles’ board and senior executive-level expertise, including her experience as chief executive officer and chief financial officer of a large public company and her extensive finance, accounting, and management expertise in marketing and strategic planning, and public board experience. Given her leadership and financial experience, Ms. Miles has been determined to be an Audit Committee financial expert by our Board.

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Item 1 — Election of Directors

Ronald D. Sugar

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Director since:2010

Age:73

Committees:

  Corporate Responsibility and Compliance (Chair)

  Executive

  Governance and Nominating

Other Public Company Boards:

  Apple Inc.

  Chevron Corporation

  Uber Technologies, Inc.

Ronald D. Sugar is the retired Chairman of the Board and Chief Executive Officer of Northrop Grumman Corporation, a global aerospace and defense company, having held these posts from 2003 through 2009.

Dr. Sugar has been a director of Chevron Corporation, a petroleum, exploration, production and refining company, since 2005, serving as the lead director and on the Management Compensation Committee and the Board Nominating and Governance Committee. Dr. Sugar has been a director of Apple Inc., a manufacturer and seller of, among other things, personal computers, mobile communication and media devices, since 2010, chairing the Audit and Finance Committee. Dr. Sugar has been a director of Uber Technologies, Inc., a personal mobility, meal delivery and logistics technology platform, since 2018, serving as the Chair of the board of directors and chairing the Nominating and Governance Committee and serving on the Compensation Committee. Dr. Sugar served as a director of Air Lease Corporation, an aircraft leasing company, from 2010 to 2020, and chaired its Compensation Committee and served on the Nominating and Corporate Governance Committee. Since 2010, he has been a senior advisor to Ares Management LLC, a privately-held asset manager and registered investment advisor. In 2014, Dr. Sugar joined the Temasek Americas Advisory Panel of Temasek Holdings (Private) Limited, a privately-held investment company based in Singapore. Dr. Sugar is a member of the National Academy of Engineering, trustee of the University of Southern California, member of the UCLA Anderson School of Management Board of Advisors, and director of the Los Angeles Philharmonic Association.

Qualifications

The Board concluded that Dr. Sugar should serve on our Board because of Dr. Sugar’s board and senior executive-level expertise, including his experience as chief executive officer and board chair of a large, highly regulated, public company and his insight in the areas of operations, government affairs, science, technology and finance.

R. Sanders Williams

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Director since:2014

Age:73

Committees:

  Corporate Responsibility and Compliance

  Governance and Nominating

Other Public Company Boards:

  Laboratory Corporation of America Holdings

  Tenaya Therapeutics, Inc.

R. Sanders Williams is the President Emeritus of Gladstone Institutes, a non-profit biomedical research enterprise, having served in this position since 2018, and was the Chief Executive Officer of the Gladstone Foundation, a not-for-profit organization supporting the Gladstone Institutes during 2018. Dr. Williams has served as Professor of Medicine at Duke University since 2018 and, from February 2021 to January 2022, acted as Interim Vice President for Research and Innovation. He has been a Professor of Medicine at the University of California, San Francisco since 2010. Dr. Williams was both President of Gladstone Institutes and its Robert W. and Linda L. Mahley Distinguished Professor of Medicine, from 2010 to 2017. Prior to this, Dr. Williams served as Senior Vice Chancellor of the Duke University School of Medicine from 2008 to 2010 and Dean of the Duke University School of Medicine from 2001 to 2008. He was the founding Dean of the Duke-NUS Graduate Medical School, Singapore, from 2003 to 2008 and served on its Governing Board from 2003 to 2010. From 1990 to 2001, Dr. Williams was Chief of Cardiology and Director of the Ryburn Center for Molecular Cardiology at the University of Texas, Southwestern Medical Center.

Dr. Williams has been a director of the Laboratory Corporation of America Holdings, a diagnostic technologies company, since 2007, serving on the Audit Committee and chairing the Quality and Compliance Committee. Since 2016, Dr. Williams also has served as a director of Tenaya Therapeutics, Inc., a biotechnology company, chairing the Compensation Committee. Tenaya Therapeutics, Inc. was a privately-held company until July 2021 when it became publicly traded. Dr. Williams was a director of Bristol-Myers Squibb Company, a pharmaceutical company, from 2006 until 2013. Dr. Williams has served on the board of directors of the Gladstone Foundation, a non-profit institution that is distinct from Gladstone Institutes, since 2012. Dr. Williams was elected to the National Academy of Medicine in 2002. Dr. Williams received his undergraduate degree from Princeton University and his medical doctorate from Duke University.

Qualifications

The Board concluded that Dr. Williams should serve on the Board because of his broad medical and scientific background, including his leadership roles in domestic and academic science settings, his deep experience in cardiology, oversight of governance of multi-hospital healthcare provider systems, leadership and development of international medical programs in Asia, and prior industry board experience.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” EACH OF THE ABOVE 12 NAMED NOMINEES.

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Corporate Governance

Corporate Governance

Board of Directors Corporate Governance Highlights

Our Board of Directors, or Board, is governed by our Amgen Board of Directors Corporate Governance Principles which are amended from time to time to incorporate certain current best practices in corporate governance. Our Corporate Governance Principles may be found on our website at www.amgen.com(1) and are available in print upon written request to the Company’s Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799. The Board’s corporate governance practices and stockholder rights include the following:

Board Governance Practices

Lead Independent Director. The independent members of the Board elect a lead independent director on an annual basis. The lead independent director has robust responsibilities and authorities as discussed below. Robert A. Eckert currently serves as our lead independent director.

Regular Executive Sessions of Independent Directors. Our independent directors meet privately on a regular basis. Our lead independent director presides at such meetings.

Board Access to Management. We afford our directors ready access to our management. Key members of management attend Board and committee meetings to present information concerning various aspects of the Company, its operations, and results, and have regular meetings in executive sessions with the Board and committees.

Board Authority to Retain Outside Advisors. Our Board and its committees have the authority to retain independent advisors and counsel. The Audit Committee has the sole authority to appoint, compensate, retain, and oversee the independent registered public accountants. The Compensation and Management Development Committee, or Compensation Committee, has the sole authority to appoint, compensate, retain, and oversee compensation advisors for senior management compensation review. The Governance and Nominating Committee, or Governance Committee, has the sole authority to appoint, retain, and replace search firms to identify director candidates and compensation advisors for our directors’ compensation review.

Independent Board Members on Key Standing Committees. The Board has four key standing committees: the Governance Committee; Audit Committee; Corporate Responsibility and Compliance Committee, or Compliance Committee; and Compensation Committee. Each member on key standing committees has been determined by the Board to be independent

under The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission, or SEC.

Regular Board and Committee Evaluations. The Board and the Audit, Compensation, Compliance, and Governance Committees each conduct an annual evaluation process. We provide more information regarding the Board and committee evaluations on page 27.

Management Succession Oversight. Our Board oversees Chief Executive Officer, or CEO, and senior management succession planning. Directors engage with potential CEO, executive, and senior management successors at Board and committee meetings. All independent members of the Board are invited to attend the Compensation Committee session on succession. Our Board also establishes steps to address succession to respond to unexpected vacancies in the event of an emergency.

Solicitation of Stockholder Perspectives. The Board believes that engagement with stockholders is a source of valuable information and perspectives on the Company. The Board has requested that management solicit input from investors on behalf of the Board and the lead independent director has also met directly with stockholders when appropriate. We provide more information regarding our stockholder engagement program on pages 31 and 51.

Majority Approval Required for Director Elections. If an incumbent director up for re-election at a meeting of stockholders fails to receive a majority of the votes cast in favor for his or her election in an uncontested election, the Board will adhere to the director resignation policy as provided in our Amended and Restated Bylaws of Amgen Inc., or Bylaws.

Director Limitation on Number of Boards. A director who is currently serving as our CEO should not serve on more than two outside public company boards. No director should serve on more than five outside public company boards. As part of its nominating process, the Governance Committee conducts an annual review of director commitment levels and shares its findings with the Board.

ContinuousBoard Refreshment. We have added seven new members to our Board since 2015 and our average Board tenure is approximately 6 years.

Director Retirement Age. The Board has established a retirement age of 75. A director is expected to retire from the Board on the day of the annual meeting of stockholders following his or her 75th birthday.

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Director Changes in Circumstances Actively Evaluated. If a director has a significant change in principal business or professional affiliation or responsibility, including a change in principal occupation, he or she shall offer his or her resignation to the Chair of the Governance Committee. The Governance Committee then determines whether to accept the resignation based on what it believes to be in the best interests of the Company and our stockholders. Directors notify the Chair of the Governance Committee prior to accepting an invitation to serve on a public or private company board to permit the Governance Committee to evaluate the relationship for a potential conflict of interest and to confirm that the director continues to have time available to perform his or her duties.

Director Outside Relationships Require Pre-Approval. Without the prior approval of disinterested members of the Board, directors should not enter into any transaction or relationship with the Company in which they will have a financial or a personal interest or any transaction that otherwise involves a conflict of interest.

Active Management of Director Conflicts of Interest. If an actual or potential conflict of interest arises for a director or a situation arises giving the appearance of an actual or potential conflict, the director must promptly inform the Chairman of the Board or the Chair of the Governance Committee. All directors are expected to recuse themselves from any discussion or decision found to affect their personal, business, or professional interests.

Stockholder Rights

Single Class of Shares. We have a single class of shares with equal voting rights. One share equals one vote.

Proxy Access. Our Bylaws permit proxy access for director nominations. Eligible stockholders with an ownership threshold of 3% who have held their shares for at least 3 years and who otherwise meet the requirements set forth in our Bylaws may have their nominees up to the number of directors constituting the greater of 20% of the total number of directors or two nominees of our Board included in our proxy materials. Up to 20 eligible stockholders may group together to reach the 3% ownership threshold. In the course of designing our proxy access provisions, we carefully considered each element in the interest of our stockholders as a whole, including that the number of stockholders who may group together (20) would afford those stockholders likely to utilize proxy access with the opportunity to do so.

Action by Written Consent. Our Amgen Inc. Restated Certificate of Incorporation permits stockholders to act by written consent in lieu of a meeting upon the request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements of our Certificate of Incorporation.

Special Meetings. Our Bylaws permit stockholders to request that the Company call a special meeting upon the written request of the holders of at least 15% of our outstanding common shares who otherwise meet the requirements set forth in our Bylaws.

No Supermajority Vote Provisions. We have a simple majority voting standard to amend our Certificate of Incorporation and Bylaws.

No Poison Pill. We do not have a shareholder rights plan, or poison pill.

Leadership Structure

Our current leadership structure and governing documents permit the roles of Chairman and CEO to be filled by the same or different individuals.

Annual Evaluation of Leadership Structure and Annual Election of Lead Independent Director. The Board evaluates, considers, and discusses the leadership structure annually. As part of this annual evaluation process, the Board reviews its leadership structure, including whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders. The Board also considers:

The effectiveness of the policies, practices, and people in place at the Company to help ensure strong, independent Board oversight;

The Company’s performance and the effect the leadership structure could have on its performance;

The Board’s performance and the effect the leadership structure could have on the Board’s performance;

The Chairman’s performance in the role;

The lead independent director’s performance in the role;

The views of the Company’s stockholders; and

The practices at other companies and trends in governance.

In the circumstance that the Board determines that it remains in the best interests of the Company and its stockholders that the CEO serve as Chairman, the independent members of the Board then elects a lead independent director from the independent members of the Board. The last review was completed in March 2022, and as a result of such review, the Board has determined that it continues to be in the best interests of the Company and our stockholders to have Robert A. Bradway, our CEO and President, serve as Chairman, coupled with an active lead independent director. As such, Mr. Bradway holds the position of Chairman, CEO, and President, and Mr. Eckert serves as the lead independent director.

Overview of Lead Independent Director Responsibilities. The responsibilities of the lead independent director are well-defined. The lead independent director engages in regular communication with the independent directors, including in independent directors sessions. The lead independent director keeps Mr. Bradway apprised of any concerns, issues, or determinations made during the independent sessions, and consults with Mr. Bradway on other matters pertinent to the Company and the Board.

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Lead Independent Director Responsibilities

The lead independent director’s responsibilities outlined in our Corporate Governance Principles include:

   Approving meeting agendas for the Board;

   Assuring that there is sufficient time for discussion of all meeting agenda items;

   Previewing the information to be provided to the Board;

   Having the authority to call meetings of the independent directors;

   Organizing and leading the Board’s evaluation of the CEO;

   Serving as a liaison between the Chairman and the independent directors;

   Leading the Board’s annual self-evaluation;

   Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

   Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

In addition to the responsibilities outlined above, our lead independent director also:

Meets with the Chairman prior to each regular meeting of the Board and its committees to discuss, provide input on, and approve the agendas;

With the Chairman, determines who attends Board meetings, such as members of management or outside advisors, and presenters;

Has one-on-one discussions with each independent director, including as part of the Board’s annual evaluation process;

Attends all committee meetings, including those committees for which he is not a member (at his discretion) and has access to all committee materials;

Has the authority to engage independent consultants;

Is regularly apprised of inquiries from stockholders;

Interviews Board candidates; and

Has an increased role in crisis and risk management, as appropriate.

Independent Directors Sessions. A meeting of the independent directors is scheduled at every regular Board meeting and the independent directors meet in an executive session without Mr. Bradway to review matters, including Company performance, management effectiveness, proposed programs and transactions, and the Board meeting agenda items. These independent sessions are organized and chaired by our lead independent director and our lead independent director provides direct feedback to Mr. Bradway after these executive sessions.

Independent Committee Leadership. The Audit, Compensation, Compliance, and Governance Committees are each composed solely of,

and led by, independent directors and provide independent oversight of management and its Board-delegated duties. In addition:

Each committee Chair meets with management in advance of meetings to review and refine agendas, add topics of interest, and review and comment on materials to be delivered to the committee;

Every director has access to all committee materials;

Each committee Chair provides a report summarizing committee meetings to the full Board at each regular meeting of the Board;

Each committee meeting includes adequate time for executive session and the committees meet in executive session on a regular basis with no members of management present (unless otherwise requested by the committee); and

Each committee effectively manages its Board-delegated duties and communicates regularly with the Chairman, lead independent director, the Board, and members of management.

Furthermore, the Compensation Committee has an effective process for succession planning and for monitoring and evaluating Mr. Bradway’s compensation and performance.

Lead Independent Director. Following the annual re-evaluation of our corporate governance structure, Mr. Eckert has been elected as the lead independent director each year since our May 2016 annual meeting of stockholders and was re-elected by our Board on March 2, 2022 to continue to serve as lead independent director subject to his re-election to the Board by our stockholders at the 2022 Annual Meeting.

Corporate Governance Structure. The Board believes our corporate governance structure, with its strong emphasis on Board independence, an active lead independent director, and strong Board and committee involvement, provides sound and robust oversight of management.

Benefits of Combined Leadership Structure. Following the annual evaluation of the governance structure, the Board continues to believe that the Company and our stockholders are best served by having Mr. Bradway in the role of Chairman (subject to his re-election to the Board) and CEO for the following reasons:

Mr. Bradway is most familiar with our business and the unique challenges we face. Mr. Bradway’s day-to-day insight into our challenges facilitates timely deliberation by the Board of important matters.

Mr. Bradway has and will continue to identify agenda items and lead effective discussions on the important matters affecting us. Mr. Bradway’s knowledge and extensive experience regarding our operations and the highly-regulated industries and markets in which we compete position him to identify and prioritize matters for Board review and deliberation.

As Chairman and CEO, Mr. Bradway serves as an important bridge between the Board and management and provides critical leadership for carrying out our strategic initiatives and confronting our challenges. The Board believes that Mr. Bradway brings a

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unique, stockholder-focused insight to assist the Company to most effectively execute its strategy and business plans to maximize stockholder value.

The strength and effectiveness of the communications between Mr. Bradway as our Chairman and Mr. Eckert as our lead independent director result in comprehensive Board oversight of the issues, plans, and prospects of our Company.

This leadership structure provides the Board with more complete and timely information about the Company, a unified structure and

consistent leadership direction internally and externally and provides a collaborative and collegial environment for Board decision making.

Flexibility of the Leadership Structure. The Board is committed to high standards of corporate governance. The Board values its flexibility to select its optimal leadership structure to best serve the Company’s and stockholders’ best interests based on the qualifications of individuals available, circumstances existing at the time, and Company’s particular needs. As such, the Board annually evaluates whether combining or separating the roles of Chairman and CEO is in the best interests of the Company and our stockholders.

The Board’s Role in Risk Oversight

Our Board oversees an enterprise-wide approach to risk management, which is designed to support execution of our strategy and achievement of the Company’s objectives to improve long-term operational and financial performance and enhance stockholder interests. Our Board believes that a fundamental part of risk management is understanding the risks that we face, adopting appropriate controls and mitigation activities for such risks, monitoring these risks, and responding to emerging developments for such risks.

We have a Company-wide Enterprise Risk Management, or ERM, program, to identify, assess, manage, report, and monitor enterprise-level risks that may affect our ability to achieve the Company’s objectives. The ERM program is overseen by our Executive Vice President and Chief Financial Officer and chaired by our Chief Audit Executive. Annually, we evaluate the greatest risks to our business, their underlying risk drivers, and the associated mitigation activities, maturity, and controls. Our Enterprise Risk Council, a cross-functional group of the Company’s business leaders representing all key business functions, works to identify and assess risks that meet the pre-established criteria constituting an enterprise-level risk, and confirms that there is clear accountability and appropriate mitigation plans are in place, including monitoring and reporting. Additionally, emerging risks that do not rise to the level of enterprise-level risks, are assessed, discussed, and actively managed and monitored. We believe that the areas of risk that are fundamental to the success of our enterprise and rise to enterprise-level risks include the areas of product development, safety and surveillance, supply and quality, value (which includes pricing) and access, sales and promotion, business development, as well as protecting our assets (financial, intellectual property, and information, including cybersecurity), all of which are managed by senior executive management reporting directly to our CEO.

The enterprise-level risks are overseen by the Board and the appropriate Board committee (as discussed below). The Board receives regular risk reporting from senior management, including an annual detailed review of the ERM program and key enterprise-level and emerging risks, as well as during the Board’s annual strategic planning process, annual budget reviews and approvals, capital plan review and approval, and through reviews of compliance issues at the applicable committees of our Board, as appropriate. For example, the risks associated with COVID-19 have the potential to affect areas of enterprise-level risk overseen by our Board, Audit Committee, Compensation Committee, and Compliance Committee and, as such, our risk mitigation plans and the effects of COVID-19 have been a topic regularly brought to and reviewed by the Board and its committees. For topics allocated to specific committees for their oversight, such as antitrust and competition regulation that is an area of the Compliance Committee’s responsibilities (as discussed below), the Compliance Committee Chair oversees the Compliance Committee’s annual calendar and meeting agendas to determine that the Company’s activities in support of its compliance with antitrust and competition regulation are assessed regularly, including a full annual review that includes Amgen’s policies, processes, and training to support such compliance, as well as regular updates of any significant industry developments at each Compliance Committee meeting. As is the practice for each of our committee Chairs, the Compliance Committee Chair reports out on these and other activities to the Board for its information and oversight at each regular Board meeting.

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Each Board committee has primary risk oversight responsibility that is aligned with its areas of focus. At each regular meeting, or more frequently as needed, the Board receives and considers committee reports, and such reports may provide additional detail on risk management issues and management’s response.

  Committee

Primary Risk Oversight Responsibility

  Governance and Nominating

   Oversees governance risk, including the assessment of each member of the Board’s independence, as well as the compliance with our Corporate Governance Principles and Board of Directors’ Code of Conduct. Also oversees Board and committee evaluations and Board succession.

  Audit

   Oversees internal controls over financial reporting, as well as internal audit and independent registered public accountants, as well as financial risk, such as capital risk, tax risk, sourcing risk, and financial compliance risk.

  Compensation and Management Development

   Oversees human capital management, as well as executive talent management, development, and succession planning. Also oversees our compensation policies and practices and incentive program administration and design, including whether such policies, practices, and incentive programs balance risk-taking and rewards in an appropriate manner (as discussed further below), align with stockholders’ interests, and are consistent with emerging best practices. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities, previously overseen by the Compliance Committee, moved to the Compensation Committee.

  Corporate Responsibility and Compliance

   Oversees non-financial compliance risk, such as regulatory risks associated with the requirements of U.S. federal health care programs, Food and Drug Administration and other regulatory agencies, and risks associated with privacy, trade compliance, antitrust and competition, anti-bribery and anti-corruption), information systems and security (including cybersecurity), value (which includes pricing) and access, government affairs, aspects of labor and employment activities and diversity, inclusion, and belonging(1), aspects of environmental sustainability, social responsibility, and corporate governance, or ESG (including environmental sustainability, corporate philanthropy, and pricing philosophy and practice), and our reputation. Also oversees staff member compliance with the global Code of Conduct.

COVID-19 Impacts to Enterprise Risk and Our Response. The far-reaching effects of COVID-19 prompted the Company to consider enterprise risk focused on rare, but high-impact events, such as global pandemics. Our business resilience program is designed to enable us to effectively prepare for and respond to crisis incidents at the global, regional, and local levels. Since the beginning of the pandemic in early 2020, we have activated appropriate crisis management and business

continuity plans and responded to the challenges presented to the operations of our business and focused on the experiences of our customers, patients, staff members, and communities. Multiple enhancements were made to our overall resilience during this pandemic, including investments in systems, automation, and innovation designed to support our remote work environment.

(1)

Responsibility of the Compliance Committee in 2021. Responsibility for these activities moved to the Compensation Committee for 2022.

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Responding to COVID-19

In the second year of the pandemic, we continued to focus on the health and safety of our staff members and the effective operation of our business, while undertaking activities to help address the pandemic, such as manufacturing COVID-19 antibody material with Eli Lilly & Company.

Our Employees. Creating a safe and healthy workplace for our staff is a priority at Amgen. Staff member access to our facilities has been in accordance with applicable government health and safety protocols and guidance issued in response to the COVID-19 pandemic and we have taken additional safety measures, including implementing occupancy limits, restricting business travel, providing personal protective equipment, temperature screening, and COVID-19 testing. In 2021, we required staff members in the U.S. and Puerto Rico to be fully vaccinated against COVID-19.(1)

Supply of Our Medicines to Patients. To date, our remote working arrangements have not significantly affected our ability to maintain

critical business operations. We have been able to serve physicians and patients as we have avoided disruptions to delivery and shortages of our supply of medicines.

Helping Our Communities. Amgen and The Amgen Foundation, Inc., a separate legal entity entirely funded by Amgen (Amgen Foundation), have been deeply engaged with our communities during the COVID-19 pandemic. For example, since the start of the pandemic, we committed $12.5 million to support local emergency response efforts in our U.S. and international communities, patient-focused organizations mounting their own response efforts, and international relief efforts by Direct Relief and International Medical Corps. Additionally, the free online learning programs supported by the Amgen Foundation, including LabXchange and the Khan Academy, have helped students continue their science education during school closures.

Codes of Business Conduct

Our Board has adopted two codes of business conduct – the Amgen Board of Directors’ Code of Conduct that applies to our Board and a global Code of Conduct that applies to our Board, all our staff, and others conducting business on our behalf. Annual training on the global Code of Conduct is required and our Board participates in such training. We also have a code of ethics for senior financial officers. To view our

codes of business conduct and ethics, please visit our website at www.amgen.com.(2) We intend to disclose any future amendments to certain provisions of our codes of business conduct and ethics, or waivers of such provisions, applicable to our directors and executive officers on our website if such disclosure is required by SEC or NASDAQ rules. There were no waivers of any of our codes of business conduct or code of ethics in 2021.

Board Meetings

The Board held 7 meetings in 2021 and all of the directors attended at least 75% of the total number of meetings of the Board and committees on which they served. S. Omar Ishrak was appointed to the Board effective in July 2021 and attended all of the meetings of the Board and of the committees on which he served after the date of his

appointment. It is the Company’s policy that all current directors attend our annual meetings of stockholders barring unforeseen circumstances or irresolvable conflicts. Each of our directors serving at the time of our 2021 Annual Meeting were present at our 2021 Annual Meeting.

Communication with the Board

Our annual meeting of stockholders provides an opportunity each year for stockholders to ask questions of our lead independent director and other members of the Board on appropriate matters. In addition, stockholders may communicate in writing with any particular director, any committee of the Board, or the directors as a group, by sending such written communication to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799. Copies of written communications received at such address will be provided to the Board or the relevant director unless such communications are considered, in the reasonable judgment of our Secretary, to be inappropriate for submission to the intended recipient(s). Examples of stockholder communications that would be considered inappropriate for submission to the Board include, without

limitation, customer complaints, solicitations, communications that do not relate directly or indirectly to our business, or communications that relate to improper or irrelevant topics. The Secretary or his designee may analyze and prepare a response to the information contained in communications received and may deliver a copy of the communication to other Company staff members or agents who are responsible for analyzing or responding to complaints or requests. Communications concerning potential director nominees submitted by any of our stockholders will be forwarded to the Chair of the Governance Committee. For information on our engagement with our stockholders since the 2021 Annual Meeting, please see page 51 of our Compensation Discussion and Analysis.

(1)

This vaccination requirement did not apply to staff who were unable to receive a COVID-19 vaccine because of qualifying medical or religious reasons.

(2)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Board Committees and Charters

The Board has four key standing committees: the Governance Committee; Audit Committee; Compliance Committee; and Compensation Committee. The Compensation Committee has delegated certain responsibilities to an Equity Award Committee. In addition, an Executive Committee of the Board has all of the powers and authority of the Board in the management of our business and affairs, except with respect to certain enumerated matters, including Board composition and compensation, changes to our Certificate of Incorporation, or any other matter expressly prohibited by law or our

Certificate of Incorporation. The Executive Committee did not meet in 2021. The Board maintains charters for each of its standing committees and these charters are evaluated annually. In addition, the Board has adopted a written set of Corporate Governance Principles and the Amgen Board of Directors’ Code of Conduct that generally formalize practices we have in place. To view the charters of our standing Board committees, our Corporate Governance Principles, and the Board of Directors’ Code of Conduct, please visit our website at www.amgen.com.(1)

Governance and Nominating Committee

Current Members:

Greg C. Garland (Chair)

Robert A. Eckert

Charles M. Holley, Jr.

Ellen J. Kullman

Amy E. Miles

Ronald D. Sugar

R. Sanders Williams

Number of Meetings Held in 2021: 5

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

Description and Key Responsibilities:

   Determines Board membership qualifications and maintains, with the approval of the Board, guidelines for selecting nominees to serve on the Board and considering stockholder recommendations for nominees. The Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement as Appendix A.

   Selects, evaluates, and recommends to the Board nominees to stand for election at the annual meeting of stockholders and to fill vacancies as they arise as more fully described in “Process for Selecting Directors, Director Qualifications, and Board Diversity” below.

   Recommends to the Board the appointment of a lead director.

   Reviews the performance of the Board and its committees and is responsible for ensuring the availability of an orientation program for new Board members and director education.

   Recommends to the Board nominees for appointment as executive officers and certain other officers.

   Evaluates and makes recommendations to our Board regarding compensation for non-employee Board members, including minimum retention and ownership levels of Company stock by Board members. (Any Board member who is also an employee of the Company does not receive separate compensation for service on the Board.)

   Monitors the independence of the Board and evaluates questions of possible conflicts of interest of members of the Board.

   Oversees the Board’s Corporate Governance Principles and the Amgen Board of Directors’ Code of Conduct applicable to members of the Board.

The Governance Committee has authority to delegate these functions to a subcommittee of its members, but no delegation of authority was made in 2021.

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Summary of Current Director Core Experiences and Skills

Our Board consists of a diverse group of highly qualified leaders in their respective fields. Most of our directors have senior leadership experience at large companies, and have gained significant and diverse management experience (including strategic and financial planning, public company financial reporting, compliance, risk management, and leadership development). Many of our directors also have public company experience (serving as chief executive officers or chief financial officers, on boards of directors and board committees) and an

understanding of corporate governance practices and trends, scientific expertise and healthcare industry experience, and bring unique perspectives to the Board. The Board and the Governance Committee believe the skills, qualities, attributes, experience, and variety of backgrounds of our directors provide us with a diverse range of perspectives to effectively address our Company’s evolving needs and represent the best interests of our stockholders.

Our Board possesses a deep and broad set of skills and experiences that facilitate strong oversight and strategic direction for a leading global innovator in biotechnology. The following chart summarizes the competencies of each director currently represented on our Board. The details of each director nominee’s competencies are included in each director nominee’s biography.

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Experience/Skills Austin Bradway Druker Eckert Garland Holley Ishrak Jacks Kullman Miles Sugar Williams Healthcare Industry, Providers and Payers Science/Technology Public Company CEO/COO/CFO Regulatory Compliance Financial/Accounting Government/Public Policy International

The lack of a “” for a particular item does not mean that the director does not possess that qualification, characteristic, skill, or experience. Each of our Board members have experience and/or skills in the enumerated areas, however, the is designed to indicate that a director has a particular strength in that area.

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Board Tenure 2 <3 Years 4 3-6 Years 4 2 7-9 Years ~6 Years Average Board Tenure Continuous Board Refreshment 7 new directors since 2015 Board Diversity Highlights Gender Diversity Racial/Ethnic Diversity 3 25% Female Directors 9 2 17% Diverse Directors 10 100% Independent directors on key standing committees

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In compliance with NASDAQ’s Board Diversity Rule, the table below provides certain highlights of the composition of our Board members and nominees.

Board Diversity Matrix (As of January 20, 2022)
  

Total Number of Directors

 12
   
  Female   Male  
 

Part I: Gender Identity

   

Directors

 3   9  
 

Part II: Demographic Background

   

African American or Black

 1   –  
   

Asian

 –   1  
   

White

 2   8  

Process for Selecting Directors, Director Qualifications, and Board Diversity

Board Composition. Board composition is one of the most critical areas of focus for the Board. Reflecting our Board’s commitment to refreshment, the Board has appointed seven new directors since 2015, including women as well as those from underrepresented communities, adding critical skills and experience to our Board in furtherance of our strategic priorities.

Our Governance Committee regularly screens and recommends candidates for nomination by the full Board and, among other things, considers feedback received during the annual Board and committee evaluation process, investor feedback, our qualification guidelines and skills matrix, director commitment levels (with consideration given to public company leadership roles and outside commitments) and diversity. The Governance Committee will consider recommendations for director candidates made by stockholders and evaluate them using the same criteria as for other candidates.

Director Qualifications and Board Diversity. Our Governance Committee is responsible for determining Board membership qualifications and for selecting, evaluating, and recommending to the Board nominees for annual election to the Board and to fill vacancies as they arise. The Governance Committee reviews regularly and reports to the Board on the composition and size of the Board, and makes recommendations, as necessary, so that the Board maintains at least the minimum number of independent directors required by applicable laws and regulations, composition requirements of the Audit and Compensation Committees, and reflects the appropriate balance of knowledge, experience, skills, expertise, and diversity advisable and required by applicable laws and regulations for the Board as a whole.

The Governance Committee and Board view diversity as a priority, considers diversity in its determinations, and seeks representation across a range of attributes. Diversity includes race, ethnicity, age, and gender and is also broadly construed to take into consideration many

other factors, including industry knowledge, operational experience, scientific and academic expertise, geography, and personal background. In an effort to best support maintaining and expanding the diversity of our Board, our Governance Committee actively seeks diverse candidates, including women and minority candidates, as part of its search for new directors.

The Governance Committee determines and oversees guidelines for selecting nominees to serve on the Board and for considering stockholder recommendations for nominees. The Amgen Inc. Board of Directors Guidelines for Director Qualifications and Evaluations are included in this proxy statement as Appendix A.

Among other things, under the Board of Directors Guidelines for Director Qualifications and Evaluations, each Board member must possess:

A demonstrated breadth and depth of management and leadership experience;

Financial and/or business acumen or relevant industry or scientific experience;

Integrity and high ethical standards;

Sufficient time to devote to the Company’s business;

The ability to oversee, as a director, the Company’s business and affairs for the benefit of our stockholders;

The ability to comply with the Amgen Board of Directors’ Code of Conduct; and

A demonstrated ability to think independently and work collaboratively.

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Continuous Board Refreshment

Our Board is committed to strong refreshment practices to continuously align the composition of the Board and its leadership structure with our long-term strategic needs. The Board, led by the Governance Committee, has an ongoing process for identifying, evaluating, and selecting directors, and these decisions are also informed by the annual Board and committee evaluation process described below. Our Governance Committee uses a variety of methods to help identify potential Board candidates and considers an assessment of current Board skills, background, diversity, independence, experience, tenure, and anticipated retirements to identify gaps that may need to be filled through the Board refreshment process.

LOGO

Current Board Composition: 7 new directors since 2015 3 women 2 ethnically/racially diverse directors Candidate Pool Sourced, Maintained and Updated Independent Search Firms Stockholders Independent Directors Select Directors Continuous Board Refreshment Governance Committee Review Review by the full Board Recommend Candidates to the Board Consider Guidelines for Director Qualifications and Evaluations (Appendix A) Consider skills matrix Include women and divers director candidates in the list from which director nominees are recommended Review independence and potential conflicts Meet candidates

Director Education

Our Board believes that director education is important to the ability of directors to fulfill their roles and supports Board members in their continuous learning. The Board encourages directors to participate in continuing education programs, and we reimburse directors for their expenses associated with this participation. During Board and committee meetings, education and information sessions are provided on specific subjects by internal and external experts. New directors also participate in our director orientation program.

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Regular Board and Committee Evaluations

Board and committee evaluations play a critical role in supporting the effective functioning of our Board. Through evaluations, our directors review where they believe our Board functions effectively and,

importantly, areas where our Board thinks there may be opportunities for improvement, including through Board refreshment.

Annual Governance Review

LOGO

Planning The Governance Committee oversees the Board evaluation process. In consultation with our lead independent director, and the committee Chairs, a framework for evaluation is established, including a review of topics for evaluation that are incorporated in the evaluation forms used by the Board and committees. Committee Evaluations and Assessment Formal annual anonymous evaluations of the Audit, Compensation, Compliance, and Governance Committees are collected, compiled, and distributed in advance of the scheduled discussion by each committee in executive session (typically in October). The evaluations include open-ended questions and space for candid commentary. All comments are unattributed, included verbatim, and shared with the full Board and each applicable committee. Each committee Chair reports out to the full Board on these assessments for review and discussion. One-on-One Discussions Our lead independent director conducts one-on-one discussions with each independent director. These candid conversations allow for direct and honest feedback on varied aspects of our Board's operations. Board Evaluation and Assessment Annual anonymous evaluations of the Board are collected, compiled, and distributed in advance of the scheduled discussion by the full Board in executive session (typically in December) and informed by the results of the committee-level evaluation discussions as well as the one-on-one discussions conducted by the lead independent director. Follow-Up Policies, practices, and the composition of our Board and its committees are modified, as appropriate, based on evaluation findings, one-on-one discussions, and follow-up items are discussed at subsequent Board and committee meetings. Ongoing Our directors are encouraged to convey ongoing feedback to our lead independent director or the Governance Committee during any executive session throughout the year.

Evaluation Results. The Audit, Compensation, Compliance, and Governance Committees each completed their committee evaluations and assessments in October 2021 and such evaluations were included as part of the total evaluation by the Governance Committee in December 2021. The Board completed its evaluation in December 2021. Each committee and the Board was considered to be operating effectively, with appropriate balance among governance, oversight, strategic, and operational matters, and each committee and the Board was satisfied with its performance.

Ongoing Feedback. Our directors provide real-time feedback throughout the year outside of the formal evaluation process and have

open access to management and third-party advisors. Additionally, executive sessions of directors (without management) are scheduled for every regular Board and committee meeting to identify any issues and assess whether meeting objectives were satisfied.

Changes Implemented. Based on the annual Board and committee evaluation process, ongoing feedback provided by directors, and one-on-one discussions between our lead independent director and each independent director, changes to Board practices have included enhancements to our committee structure and composition, additional presentations on various topics, and the addition of new directors.

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Director Independence

At least annually, the Governance Committee reviews the independence of each non-employee director and makes recommendations to the Board and the Board affirmatively determines whether each director qualifies as independent. Each director must keep the Governance Committee fully and promptly informed as to any development that may affect the director’s independence.

The Board has determined that each of our non-employee directors: Wanda M. Austin; Brian J. Druker; Robert A. Eckert; Greg C. Garland; Charles M. Holley, Jr.; S. Omar Ishrak; Tyler Jacks; Ellen J. Kullman; Amy E. Miles; Ronald D. Sugar; and R. Sanders Williams; and Fred Hassan (who served as a director during part of 2021) was independent during 2021 under The NASDAQ Stock Market listing standards and the requirements of the SEC. Mr. Bradway is not independent based on his service as our CEO and President. Mr. Bradway is the only director who also serves in a management capacity. In making its independence determinations, the Board reviewed direct and indirect transactions and relationships between each director or any member of his or her immediate family, and us or any of our subsidiaries or affiliates based on information provided by the director, our records, and/or publicly available information.

All of the reviewed transactions and arrangements were entered into in the ordinary course of business and none of the business transactions, donations, or grants involved an amount that (i) exceeded the greater of 5% of the recipient entity’s revenues or $200,000 with respect to transactions where a director or any member of his or her immediate family or spouse served as an employee, officer, partner, director, or controlling shareholder, or (ii) exceeded $10,000 with respect to professional or consulting services provided by entities at which directors serve as professors or employees.

The following types and categories of transactions, relationships, and arrangements were considered by our Board in making its independence determinations:

Each of the independent directors (or their immediate family members) currently serves or has previously served within the last

three years as a professor, trustee, director, or member of a board, advisory board, council, or committee for one or more colleges, universities, or non-profit charitable organizations, including research or scientific institutions, to which the Amgen Foundation has made grants or matching donations under the Amgen matching gift program that is available to all of our employees and directors.

Each of the independent directors (or their immediate family members) currently serves, or has previously served within the last three years, as a member of the board of directors, the board of trustees, or an advisory board for an entity with which Amgen has business transactions or to which Amgen or the Amgen Foundation makes donations or grants. These business transactions include, among other things, purchasing supplies, equipment and software licenses, payment of fees or memberships, and expenses relating to repair and maintenance, clinical trials, research and development and training, sponsorship of healthcare programs and conferences, financial advisory, investment management, investment advisory and consulting services, and reimbursement of business-related expenses incurred by our staff members (such as for transportation, gas, and food purchases).

Wanda M. Austin, Brian J. Druker, Tyler Jacks, and R. Sanders Williams currently serve as professors for universities to which Amgen has made payments for certain business transactions such as symposiums, conferences and exhibits, postdoctoral research programs, clinical trials, training and research and development, software licenses and maintenance, as well as for grants from the Amgen Foundation.

None of the directors, directly or indirectly, provides any professional or consulting services to us and none of the directors currently has or has had any direct or indirect material interest in any of the above transactions and arrangements. The Board determined that these transactions and arrangements did not warrant a determination that any of our directors were not independent.

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Governance Committee Processes and Procedures for Considering and Determining Director Compensation

The Governance Committee has the authority to evaluate and make recommendations to our Board regarding director compensation.

The Governance Committee conducts this evaluation periodically by reviewing our director compensation practices against the practices of an appropriate peer group and the Governance Committee has the authority to retain consultants to advise on director compensation matters, including in support of the Governance Committee’s periodic review of director compensation practices.

In 2020, the Governance Committee engaged Frederic W. Cook and Co., or FW Cook, to provide advice regarding director compensation.

FW Cook reported directly to the Governance Committee and attended the Governance Committee meeting to evaluate director compensation. No executive officer has any role in determining or recommending the form or amount of director compensation.

Based on the analysis provided by FW Cook, the Governance Committee determined to make changes to director compensation effective for 2021, the first increase since 2013, to align with market practice and attract and retain high-quality director candidates in a competitive global marketplace. For more information regarding director compensation, see “Director Compensation—2021 Director Compensation.

Audit Committee

Current Members:

Charles M. Holley, Jr.* (Chair)

Wanda M. Austin

Ellen J. Kullman*

Amy E. Miles*

*Audit Committee financial expert

Others who served in 2021:

Fred Hassan (until retirement at 2021 Annual Meeting)

Number of Meetings Held in 2021: 10

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC, including the requirements regarding financial literacy and sophistication.

Description and Key Responsibilities:

   Oversees our accounting and financial reporting process and the audits of the financial statements, as required by NASDAQ.

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the oversight of our financial accounting and reporting, the underlying internal controls and procedures over financial reporting, and the audits of the financial statements.

   Has sole authority for the appointment, compensation, and oversight of the work of the independent registered public accountants.

   Reviews and discusses, prior to filing or issuance, with management and the independent registered public accountants (when appropriate) our audited consolidated financial statements to be included in our Annual Report on Form 10-K and earnings press releases.

   Approves related party transactions.

   Reviews any violations or alleged violations of the Company’s Code of Ethics for the CEO and Senior Financial Officers.

Audit Committee Oversight of the Independent Registered Public Accountants

•   Auditor Selection. Evaluates the qualifications and performance of our independent registered public accountants each year and appoints the independent registered public accountants annually.

•   Audit Partner Selection. Participates directly in the selection of the lead engagement partner through an interview process.

•   Audit Firm Evaluation. Considers the quality and efficiency of the services provided, the independent registered public accountants’ technical expertise and knowledge of our operations and industry.

•   Audit Services. Pre-approves services.

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Corporate Governance

Corporate Responsibility and Compliance Committee

Current Members:

Ronald D. Sugar (Chair)

Brian J. Druker

S. Omar Ishrak (since July 30, 2021)

Tyler Jacks

R. Sanders Williams

Number of Meetings Held in 2021: 5

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

Description and Key Responsibilities:

   Oversees our compliance program and reviews our programs in a number of areas governing ethical conduct including:

-  U.S. federal health care program requirements;

-  U.S. Food and Drug Administration requirements and other regulatory agency requirements, including good manufacturing, clinical and laboratory practices, drug safety and pharmacovigilance activities;

-  interactions with members of the healthcare community;

-  the Company’s Corporate Integrity Agreement;

-  anti-bribery/anti-corruption risks;

-  environment, health, and safety;

-  information security, including cybersecurity; and

-  aspects of labor and employment activities and diversity, inclusion and belonging(1); and

-  government affairs, including the Political Action Committee.

   Receives regular updates on value (which includes pricing) and access, political, social, and environmental trends, and public policy issues that may affect our reputation, including our business or public image, and reviews our elements of our corporate responsibility (including environmental sustainability), political, and philanthropic activities.

About Our Compliance Program

Amgen’s Compliance Program is designed to promote ethical business conduct and compliance with applicable laws and regulations. The key objectives of our compliance program operations include:

Developing policies and procedures;

Providing ongoing compliance training and education;

Auditing and monitoring compliance risks;

Maintaining and promoting avenues for staff to raise concerns without fear of retaliation, including anonymously through a business conduct hotline;

Conducting investigations;

Responding appropriately to any compliance violations;

Taking appropriate steps to detect and prevent recurrence, including by implementing appropriate corrective and preventive actions; and

Promoting an ethical culture.

Our Chief Compliance Officer, who reports to the CEO and the Compliance Committee, oversees the ongoing operations of the compliance program.

(1)

Beginning in 2022, oversight of those aspects of labor and employment activities (including diversity, inclusion and belonging), previously overseen by the Compliance Committee, moved to the Compensation Committee.

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Our Approach to Environmental Sustainability, Social Responsibility, and Human Capital Management

Amgen’s ESG strategy begins with our mission to serve patients and is supported by our long-standing focus on using resources responsibly to support the sustainability of our business and the global environment in which we and our patients live.

ESG Oversight and Governance

ESG at Amgen is governed at the highest levels and includes Board and committee oversight, executive-level leadership, and subject-matter experts who lead our ESG efforts across our business.

Board Oversight. The Board and its applicable committees provide guidance and oversight to management with respect to ESG matters. The Compliance Committee assists the Board in overseeing our activities in areas that include environmental sustainability, diversity, inclusion and belonging, and access to medicines. Beginning in 2022, oversight of diversity, inclusion and belonging shifted to the Compensation Committee, the committee that also provides oversight of our approach to human capital management. The Governance Committee oversees the Company’s corporate governance activities and Board membership. Additionally, management shares feedback received from our stockholders with the Board, including in connection with our governance-focused engagement program. For additional discussion, please see “Positive 2021 Say on Pay Vote Outcome and Compensation Design Changes in Response to 2021 Stockholder Input” in our Compensation Discussion and Analysis.

Management Leadership. A cross-functional, executive-level governance council sets our overall ESG strategy, provides guidance on program implementation, and oversees the continuing enhancement of our approach to ESG. This council, chaired by our Senior Vice President, Corporate Affairs, regularly evaluates current and emerging ESG-related risk topics that are relevant to our business, including those considered as part of our ERM program. For additional information, please see “The Board’s Role in Risk Oversight” previously discussed.

Our ESG framework currently includes four strategic pillars—Healthy People, Healthy Society, Healthy Planet, and A Healthy Amgen—that serve as organizing principles facilitating our ability to address the interconnectivity of issues in a more holistic way across our business.

Amgen’s ESG Framework

LOGO

Program Implementation.Each pillar is supported by an initiative steering committee and, together with the oversight of our executive leadership, individual programmatic elements are managed at a business function level. Since 2021, to further integrate ESG across the organization, our Compensation Committee added an ESG goal to our Company performance goals for our annual cash incentive plan. For additional information, please see “Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance” in our Compensation Discussion and Analysis.

In addition to our history of strong corporate governance practices, examples of our ESG initiatives include our endeavors to strengthen science education and inspire the next generation of scientists, expand access to our medicines and support efforts to strengthen healthcare systems to better serve patients in need worldwide, and pursue a more environmentally sustainable business model. For additional information, please see “Board of Directors Corporate Governance Highlights” previously discussed.

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Environmental Sustainability

As a science-based company committed to advancing human health, Amgen recognizes the importance of climate change on human health around the world. We have a long-standing objective to conduct environmentally responsible operations and regularly set targets to challenge ourselves to deliver further improvements. Since 2007, we have successfully advanced our environmental sustainability program while substantially increasing our global production capacity and patient reach.

Building on the successful execution of our 2013-2020 conservation targets, we launched a new environmental sustainability plan in 2021 (our third since 2007) that includes a target of achieving carbon neutrality in our operations by 2027, while also aiming to further reduce our water use (by 40%) and waste disposed (by 75%).(1)

LOGO

Our 2027 Environmental Sustainability Plan. To achieve our 2027 goals, we plan to harness our innovative capabilities to help combat climate change and preserve natural resources. We expect these efforts to help us become not just more environmentally sustainable but also more flexible and productive, resulting in reductions in operating costs from such efficiencies over the same period.

Our 2027 plan is designed to drive specific environmental sustainability projects across our operations, including continued investment in highly resource efficient biomanufacturing, smart and integrated facility design, use of on-site solar and other renewable energy sources, electric vehicle fleet conversion, treatment and reuse of water, the reduction and recycling of single-use plastics, and the reduction of consumables packaging. This plan also includes activities to further integrate the potential risks and opportunities from climate change into our existing processes for strategic planning, analysis, and risk management.

The Road to Net Zero. To help achieve our goal of carbon neutrality by 2027(1), Amgen is focusing on the use of innovative technologies and efficiency projects to reduce carbon emissions from our owned and operated facilities, in addition to sourcing renewable energy. Where renewable sources are not available, we expect to prioritize offsetting based on the quality of the credit or offset.

Sustainability by Design. Amgen helped to invent the processes and tools that created the global biotech industry. As we continue to grow

and innovate, we are pioneering advanced technologies and implementing more environmentally responsible approaches throughout the Company to increase operational efficiency and reduce our environmental footprint.

Our next-generation biomanufacturing facility in Singapore, which began commercial production in 2017, is an example of our innovative capability at work. This redesign of our approach to biomanufacturing dramatically reduces the scale and costs of making biologic medicines, and vastly reduces water and energy use, while maintaining a reliable, high-quality, compliant supply of medicines.

LOGO

The success of our facility in Singapore, along with U.S. corporation tax incentives to invest in innovation and advanced technologies, led to our building a second such plant in the U.S. in Rhode Island. This facility was licensed by the U.S. Food and Drug Administration in January 2022 and will support product volume growth, while delivering environmental and operating efficiencies.

We continue to apply innovation to our facilities with multiple ongoing projects, including in connection with the expansion of our U.S. plants. In 2021, we commenced construction on two new facilities (a final product assembly and packaging plant in Ohio and a multi-product drug substance facility in North Carolina). These facilities are expected to support our ability to meet the demand for our medicines, utilize cutting-edge technologies to be more efficient and environmentally friendly than traditional plants, and bring hundreds of full-time jobs to the regions while expanding our access to diverse talent.

(1)

Carbon neutrality goal refers to Scope 1 and 2. Reductions take into account only verified reduction projections, do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

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Sustainable Value Chain. Our footprint and focus on sustainability extend beyond our own employees and facilities. Amgen’s 2027 environmental sustainability plan includes engaging with our suppliers and contactors to evaluate the carbon impact throughout our value chain and identify reduction opportunities.

ESG Reporting.Informed by insights from our investors, we enhanced our ESG reporting in 2021 by expanding our latest Environmental, Social, and Governance Report by mapping our reporting to the Sustainability Accounting Standards Board (SASB) standards for our industry, disclosing our annual Consolidated EEO-1 Report, and providing additional metrics on the diversity of our workforce.

Since 2010, Amgen has reported to CDP (formally the Carbon Disclosure Project). Over time, CDP’s disclosure platform for climate change has evolved to contain over 25 questions (within its governance, risks and opportunities, strategy, targets and emissions modules) that are aligned with the recommendations of the Task Force on Climate-related Financial Disclosures, or TCFD; this platform is now nearly in full alignment with the TCFD. We continue to report to the CDP as completely as possible and, in 2022, we are undertaking a TCFD-aligned scenario analysis to improve our understanding of the physical and transitional effects of climate change as well as inform our future reporting.

United Nations Global Compact. We are a signatory to the United Nations Global Compact, a voluntary initiative based on commitments to implement universal sustainability principles and take steps to support the United Nations Sustainable Development Goals.

Social Responsibility

Improving Patient Access to Medicines. Through patient assistance programs, expanded access to investigational therapies, donations, and other initiatives, Amgen has developed support programs for eligible patients around the world as they seek to obtain the medicines they need.

Amgen Safety Net Foundation (ASNF), a separate legal entity entirely funded by Amgen, supports qualifying patients in the U.S. who might go without important medicines because of financial limitations, by providing our medicines at no cost. In 2021, the commercial value of Amgen’s medicines provided at no cost to uninsured or underinsured patients by ASNF was over $2 billion.(1)

Since 2018, Amgen has also donated approximately $140 million worth of Amgen cancer treatment and supportive care medicines(1) for distribution to patients in more than 30 developing countries through Direct Relief, a leading non-governmental organization.

We continue to offer and implement value-based contracts in an effort to help improve patient access to medicines and offer stakeholders greater budget predictability.

Advancing Health Equity. As part of our mission to serve patients, we are working to improve the diversity and representation of racial and ethnic minority populations in clinical trial research at Amgen and to advance solutions and increase dialogue regarding this area across the industry.

We recognize the importance of a patient-centric approach to clinical research and our Representation in Clinical Research (RISE) team is working with groups within Amgen and outside of the business towards exceeding industry standards for clinical trial diversity and representation and helping Amgen develop new medicines studied in participants who better reflect the populations affected by certain diseases or conditions. We also continue building relationships with leaders and organizations in diverse communities to help address healthcare disparities, improve disease state awareness, and increase dialogue in this area.

Supplier Diversity and Responsible Sourcing. We aspire to double our supplier diversity spend, and triple our Black-owned business spend, in the U.S. by 2023.(2) Our supplier diversity program is designed to identify, develop, and utilize small, disadvantaged, veteran, LGBTQ, minority, disabled, and women-owned business enterprises, as well as companies located in historically underutilized business zones, in our procurement of goods and services. Our efforts include mentoring and development opportunities to further strengthen the leadership capabilities of these diverse suppliers and contactors.

All staff members are guided by the Amgen Values and global Code of Conduct and, similarly, we request our suppliers to conduct their businesses in alignment with our mission and values. Our supplier sustainability program focuses not only on quality, cost, and reliability but also on a wide range of sustainability and social responsibility considerations, such as business ethics, labor and human rights, and environmental impacts.

Science Education. The Amgen Foundation seeks to advance excellence in science education to inspire the next generation of innovators and invest in strengthening communities where our staff members live and work.

Since its inception over 30 years ago, the Amgen Foundation has contributed more than $375 million to non-profit organizations around the world that reflect our core values and complement Amgen’s dedication to impacting lives in inspiring and innovative ways.

LabXchange, developed at Harvard University with the financial support of the Amgen Foundation, is a free online science education platform that provides students around the world with access to personalized instruction, virtual lab experiences, and networking opportunities across the global scientific community. In 2021, with the Amgen Foundation’s support, LabXchange launched a digital curriculum focused on examining racial inequity in healthcare, education, and STEM fields in the U.S.

The Amgen Foundation is the exclusive biology content partner of Khan Academy, a leading online learning platform, and approximately

(1)

Valued at wholesale acquisition cost.

(2)

Measured against a 2019 baseline.

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15 million users accessed Khan Academy’s free biology lessons in 2021. Through an expanded, multi-year partnership with the Amgen Foundation in support of science learning and education equity, Khan Academy is creating a comprehensive offering of biology resources for students and teachers worldwide and expanding its partnerships with school districts facing budget shortfalls.

Additionally, the Amgen Foundation continued to expand the Amgen Biotech Experience (ABE), an innovative science education program that empowers high school teachers to bring biotechnology education into their classrooms. In 2021, the second cohort of the ABE Master Teacher Fellowship was announced with twelve fellows from around the globe who each receive a stipend and targeted support to develop a curriculum project to be shared with the ABE international community.

The Amgen Scholars Program makes it possible for undergraduates around the globe to engage in cutting-edge research experiences in leading graduate laboratories and learn more about biotechnology and drug discovery.

Our Community. In 2021, The Amgen Foundation provided grants totaling $3 million to more than 30 U.S.-based nonprofits in support of racial and social justice initiatives, economic empowerment, and equal opportunity in education.

Amgen and the Amgen Foundation have been engaged with our community during the pandemic. For additional information, please see “Responding to COVID-19” previously discussed.

The Amgen Foundation also provides programs and resources to empower individual Amgen staff in their charitable activities in our community, including through a matching gift program and by providing service grants to non-profit organizations where staff members regularly volunteer.

Human Capital Management

Our Board has a key role in the oversight of our culture, setting the tone at the top, and holding management accountable for maintaining high ethical standards. The Board believes that human capital management, including our diversity, inclusion, and belonging initiatives, are important to our success. The Compensation Committee assists the Board in providing oversight of human capital management and, beginning in 2022, labor and employment and diversity, inclusion, and belonging oversight responsibilities, previously overseen by the Compliance Committee, moved to the Compensation Committee. We conduct regular staff member engagement assessments that gather feedback on topics, including on the overall engagement of staff members, diversity, inclusion, and belonging, and our culture of compliance, and the results of these surveys are discussed with our workforce and the Board.

Amgen places significant value on fostering and enabling growth of staff, both personally and professionally, and we aim to provide a safe, healthy, innovative, and diverse work environment for our staff.

Our Social Architecture. Since Amgen’s founding in 1980, our staff members have directed their intelligence and enthusiasm toward our mission to serve patients. The combination of our mission, our aspiration to be the world’s best human therapeutics company, our strategy, our well-defined set of Amgen Values, and the clear leadership attributes that we expect from our staff members, form the “social architecture” that defines our unique culture. This social architecture has been a key enabler of Amgen’s worldwide growth from an early pioneer in the biotech industry to a leading innovator.

The Amgen Values were formalized in 1996 and continue to serve as the principles that guide the way we conduct business.

Amgen Values

Be Science-Based

Trust and Respect

Each Other

Compete Intensely

and Win

Ensure Quality

Create Value for

Patients,

Staff, and

Stockholders

Work in Teams
Be Ethical

Collaborate,

Communicate, and Be

Accountable

Diverse and Inclusive Workforce. Consistent with the Amgen Values, we are working to bring the diversity of the world community into the Amgen community. We believe that a diverse and inclusive culture fosters innovation, which supports our ability to serve patients. Further, we also believe our global presence is strengthened by having a workforce that reflects the diversity of the patients we serve. It is with these beliefs in mind that we have continued to strengthen and grow our culture of diversity, inclusion, and belonging.

Our Diversity, Inclusion and Belonging Council is led by our executive leadership and is responsible for overseeing our strategy to further a diverse and inclusive workplace, with an ongoing focus on women in leadership and minority representation. With endorsement from executive management and engagement with senior leaders across the organization, we are implementing a global strategy designed to leverage our diversity and create a more inclusive workplace.

We are engaging in activities and setting goals to improve our focus around diversity, inclusion, and belonging, including the launch of a mandatory unconscious bias training program that was completed by 100% of our U.S., Canada, and Puerto Rico staff members in 2020 (with a global rollout in 2021) and an online learning journey with tools and resources that guides staff members on the role they play in advancing diversity, inclusion and belonging throughout the organization.

 

 

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Each of our eleven Employee Resource Groups, dedicated to representing, supporting, and celebrating the diversity of our staff, are supported by a sponsor from our senior executive leadership team.

Amgen Employee Resource Groups

Amgen Asian
Association (AAA)

Amgen Black
Employee Network
(ABEN)

Ability Bettered through Leadership and
Education (ABLE), a resource group for those with
disabilities, visible and invisible

Amgen Early Career
Professionals (AECP)

Amgen International
Network (AIN)

Amgen Indian
Subcontinent
Network (AISN)

Amgen Latin Employee
Network (ALEN)

Amgen LGBTQ and
Allies Network
(PRIDE)

Amgen Veterans
Employees Network
(AVEN)

Women Empowered
to be Exceptional
(WE2)

Women in Information
Systems Enrichment

(WISE)

Amgen is a founding member of OneTen, a coalition of many of the world’s largest, best-known companies that aims collectively to hire one million Black Americans (with a specific focus on those without four-year college degrees) into good-paying family-sustaining jobs over the next ten years.

Amgen is taking a leadership role in the greater Los Angeles region, where we are headquartered, to help expand the coalition of organizations that share our desire to offer opportunities to diverse talent.

Attracting and Developing Talent. We recognize the importance of attracting, motivating, developing, and retaining top global talent and skilled staff members. We compensate our staff members based on their roles, experience, and performance, provide wellness and work-life resources, as well as support employees in giving back and volunteering in their local communities. To support the development of our staff, we provide a variety of programs, including leadership development programs, virtual instructor-led courses, and self-paced learning options.

Our benefit programs are generally broad-based, promote health and overall well-being, and emphasize saving for retirement. Amgen continues to pride itself on industry-leading, family-friendly offerings for families of all compositions, including, in the U.S. and Puerto Rico, on-site child care at certain of our facilities, adoption assistance, resources for elder care and behavioral health, and paid parental leave for all Amgen staff members who have or adopt, or become a foster parent or legal guardian for a child. Globally, comparable benefit programs are offered with the same health and well-being goals, while also designed to comply with local statutory requirements.

(For more information regarding our approach to human capital resource management, including activities in support of workplace safety and diversity, please see our Form 10-K for the year ended December 31, 2021.)

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Compensation and Management Development Committee

Current Members:

Robert A. Eckert (Chair)

Wanda M. Austin

Brian J. Druker

Greg C. Garland

S. Omar Ishrak (since July 30, 2021)

Tyler Jacks

Others who served during 2021:

Fred Hassan (until retirement at 2021 Annual Meeting)

Number of Meetings Held in 2021: 6

Independent Compensation Consultant: FW Cook

Each member has been determined by the Board to be independent under The NASDAQ Stock Market listing standards and the requirements of the SEC.

  Description and Key Responsibilities:

   Assists the Board in fulfilling its fiduciary responsibilities with respect to the oversight of the Company’s compensation plans, policies, and programs with a focus on encouraging high performance, promoting accountability and adherence to Company values, and aligning with the interests of the Company’s stockholders.

   Approves all executive officer compensation.

   Oversees human capital management and succession planning for senior management, including that our approaches to management development are effective in attracting, developing, and retaining talented leadership. Beginning in 2022, oversight of those aspects of labor and employment and diversity, inclusion and belonging activities previously overseen by the Compliance Committee, moved to the Compensation Committee.

   Oversees the Board’s relationship with stockholders on executive compensation matters, including stockholder outreach efforts, stockholder proposals, advisory votes, communications with proxy advisory firms, and related matters.

Executive Compensation Website

We maintain a website accessible throughout the year at www.amgen.com/executive compensation(1), which provides a link to our most recent proxy statement and invites our stockholders to fill out a survey to provide input and feedback to the Compensation Committee regarding our executive compensation policies and practices.

Equity Award Committee

The Equity Award Committee, with Robert A. Bradway currently the sole member, assists the Board by determining equity-based awards to non-Section 16 officers and employees at the level of vice president or below, consistent with the equity grant guidelines established by the Compensation Committee, and acted five times in 2021.

Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 2021

Compensation Committee Determination of Compensation. Generally, by the first calendar quarter of each year, the Compensation Committee reviews and approves Company performance goals and objectives for the current year and evaluates the CEO’s performance for the previous year in light of the Company performance goals and objectives established for the prior year. The Compensation Committee evaluates the performance of the CEO within the context of the financial and operational performance of the Company, considers competitive market data, and establishes the CEO’s compensation based on this evaluation as well as the compensation for each executive officer.

Values and Components. The values of each component of total compensation (base salary, target annual cash incentive awards, and equity awards) for the current year, as well as total annual compensation for the prior year (including the value of equity holdings, potential change of control payments, and vested benefits under our Retirement and Savings Plan, Supplemental Retirement Plan, and Nonqualified Deferred Compensation Plan as of the end of the last fiscal year) are considered at this time. Final determinations regarding our

CEO’s performance and compensation are made during an executive session of the Compensation Committee and are reported to and reviewed by the Board in an independent directors’ session.

Executive Officers. Our Compensation Committee determines compensation for the executive officers (other than the CEO) based, in part, on the recommendations of our CEO regarding base salary, annual cash incentive awards, and equity awards. In determining compensation recommendations for each Named Executive Officer, or NEO, our CEO reviews comparative peer group data, as well as the performance of the executive. The Compensation Committee has typically followed these recommendations.

Executive Sessions.Each Compensation Committee meeting includes adequate time for executive session and the Compensation Committee meets in executive session on a regular basis with no members of management present (unless otherwise requested by the Compensation Committee).

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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Delegation of Authority. The Compensation Committee has authority to delegate any of its functions to a subcommittee of its members. No delegation of authority was made in 2021.

Independent Compensation Consultant. The Compensation Committee continued to engage FW Cook, an independent compensation consultant, to provide advice regarding executive compensation and executive compensation trends and developments, compensation designs, and equity compensation practices, market data as requested, and opinions on the appropriateness and competitiveness of our executive compensation programs relative to market practice. FW Cook reported directly to the Compensation Committee and attended regularly scheduled meetings of the Compensation Committee (including meeting in executive session with the Compensation Committee, as requested). Each year the Compensation Committee reviews the independence of FW Cook and whether any conflicts of interest exist. After review and consultation with FW Cook, the Compensation Committee has determined that FW Cook is independent and there is no conflict of interest resulting from retaining FW Cook currently or during the year ended December 31, 2021. In performing its analysis, the Compensation Committee

considers the factors set forth in the SEC rules and The NASDAQ Stock Market listing standards.

Peer Group Review. In setting executive compensation, the Compensation Committee compares the Company’s pay levels and programs to those available for the Company’s competitors for executive talent and uses this comparative data as a guide in its review and determination of compensation. Our Compensation Committee annually considers and selects an appropriate peer group (consisting of biotechnology and pharmaceutical companies), based, in part, on the recommendations of FW Cook, and, for each NEO, the Compensation Committee reviews the compensation levels and practices of our peer group, which for our NEOs, other than the CEO, are based on reports prepared by management from information contained in compensation surveys and proxy statements. FW Cook provides the Compensation Committee with market data, an annual report on the compensation levels and practices of our peer group, and compensation recommendations for the CEO position.

Compensation Risk Management. In cooperation with management, FW Cook assesses the potential risks arising from our compensation policies and practices as discussed more fully below.

Compensation Risk Management

Annual Risk Management Assessment. On an annual basis, management, working with the Compensation Committee’s independent compensation consultant, conducts an assessment of the Company’s compensation policies and practices for all staff members generally, and for our staff members who participate in our sales incentive compensation program, for material risk to the Company. Compensation-related risks from COVID-19 were evaluated as part of this assessment for 2021.

Results of Risk Management Assessment.The results of this assessment are reviewed and discussed with the Compensation Committee. Based on this assessment, review and discussion, we believe that, through a combination of risk-mitigating features and incentives guided by relevant market practices and our Company performance goals, our compensation policies and practices do not present risks that are reasonably likely to have a material adverse effect on us.

Factors That Discourage Excessive Risk-Taking.In evaluating our compensation policies and practices, a number of factors were identified which the Company, the Compensation Committee, and its independent consultant believe discourage excessive risk-taking, including:

Mix of Incentives and Metrics. Our compensation programs consist of a mix of incentives and metrics (financial and operational) that are tied to varying performance periods and are designed to balance our need to drive our current performance with the need to position the Company for long-term success.

Company-wide Results.Company-wide results are the most

important factor in determining the amount of an annual cash incentive award, one of our mix of incentives, for each of our staff members.

Emphasis on Long-Term Performance. We cap short-term incentives and make LTI equity awards a component of compensation for nearly all of our full-time staff members. In particular, the CEO and the other executive officers participate in compensation plans that are designed so that the largest component of their compensation is in the form of LTI equity awards to ensure that a significant portion of their compensation is associated with long-term, rather than short-term, outcomes, which aligns these individuals’ interests with those of our stockholders.

Equity Award Grant Practices. We employ appropriate practices with respect to equity awards: we do not award mega-grants, discounted stock options, or immediately vested equity to staff members; and we have grant guidelines that generally limit the grant date for our equity grants to the third business day after our announcement of quarterly earnings.

Robust Stock Ownership and Retention Guidelines. We have robust stock ownership guidelines for vice presidents and above that require significant investment by these individuals in our Common Stock. We require that each officer who has not met his or her required ownership guidelines hold shares of our Common Stock acquired through the vesting of restricted stock units, the payout of performance units, and the exercise of stock options (net of shares retained by us to satisfy associated tax withholding requirements and exercise price amounts) until such officer has reached his or her required stock ownership level.

LOGO ï 2022 Proxy Statement37


Corporate Governance

Comprehensive Performance Evaluations. Our Company values and leadership behaviors are an integral part of the performance assessments of our staff members and are particularly emphasized in our assessment tools at higher positions. These evaluations serve as an important information tool and basis for compensation decisions.

Clawback Policy. We have a clawback policy that requires our Board to consider recapturing past cash or equity compensation payouts awarded to our executive officers if it is subsequently determined that the amounts of such compensation were determined based on financial results that are later restated and the executive officer’s misconduct caused or partially caused such restatement.

Recoupment. We have recoupment provisions that expressly allow the Compensation Committee or management, as appropriate, to consider employee misconduct that caused serious financial or reputational damage to the Company when determining whether an employee has earned an annual cash incentive award or the amount of any such award.

The Compensation Committee has adopted an executive officer equity recoupment policy that provides the Compensation Committee with the ability to cause the forfeiture and cancellation of unvested equity awards and any unexercised portion of any stock options (granted after December 31, 2020) if an executive officer is terminated for engaging in misconduct that caused serious financial or reputational damage to the Company (including, but not limited to, a financial restatement).

Disclosure. Subject to our recoupment and clawback policies and provisions, we intend to disclose the general circumstances of any application of our recoupment or clawback policies and provisions against any executive officer (current or former) and the aggregate amount of compensation recovered.

No Hedging or Pledging. Our Insider Trading Policy prohibits pledging or purchasing of our Common Stock on margin(1) and hedging the economic risk of our Common Stock (as discussed more fully below).

Mandatory Global Code of Conduct Compliance Training. We require training on our global Code of Conduct and other policies that educate our staff members on appropriate behaviors and the consequences of taking inappropriate actions.

Pricing Policies and Controls. Amgen’s drug pricing governance framework is designed to help ensure that our pricing actions around the globe are legally compliant, financially sound, and aligned with our values and corporate objectives. Our approach to pricing includes training, standard operating procedures, policies, approval mechanisms for price increases and price policy exceptions, and other controls that balance regional and country autonomy with centrally managed price discipline. Our Board, with the assistance of the Compliance Committee, has a key role in the oversight of pricing risk and regularly receives presentations from management on drug pricing practices and trends.

Prohibition on Hedging

Under our global Insider Trading Policy, all of our Board members and staff members, including our NEOs, consultants, contract workers, secondees, and temporary staff worldwide are considered “Covered Persons.” It is against the Insider Trading Policy for Covered Persons to directly or indirectly participate in transactions involving trading activities in our securities that, by their nature, are aggressive or speculative, or may give rise to an appearance of impropriety. Covered Persons may not:

Engage in short sales (sales of stock that the seller does not own or a sale that is completed by delivery of borrowed stock) with respect to our securities;

Engage in transactions that hedge or offset, or are designed to hedge or offset, any decrease in the market value of Amgen stock;

Purchase or pledge Amgen stock on margin or as collateral to secure a loan or other obligation(1); or

Enter into any derivative or similar transactions with respect to our securities.

Examples of prohibited derivative transactions include, but are not limited to, purchases or sales of puts and calls (whether written or purchased or sold), options (whether “covered” or not), forward contracts, including but not limited to prepaid variable forward contracts; put and call “collars” (“European” or “American”), “equity” or “performance” swap or exchange agreements, or any similar agreements or arrangements however denominated, in our securities.

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

38    LOGO ï 2022 Proxy Statement


Corporate Governance

Pay Ratio

Following is a reasonable estimate, prepared under applicable SEC rules, of the ratio of the annual total compensation of our CEO to the median of the annual total compensation of our other staff members, calculated in accordance with the requirements of Item 402(c)(2)(x) of Regulation S-K. The Company determined our median employee based on total direct compensation paid to all of our staff members worldwide and recorded in our global human resources systems as of December 31, 2021. Total direct compensation included base salary, annual cash incentive awards earned for the period (and target sales incentive awards for our sales force), and the annual grant value of LTI equity awards during 2021. Earnings of our staff members outside of the U.S. were converted to U.S. dollars using currency exchange rates

as of December 31, 2021. No cost-of-living adjustments were made. We then determined the annual total compensation of our median employee for 2021 which was $130,589. As disclosed in the “Summary Compensation Table” appearing on page 73, our CEO’s annual total compensation for 2021 was $21,721,154. Based on the foregoing, the ratio of the annual total compensation of our CEO to that of the median staff member was 166 to 1. For information on the determination of executive compensation, please see “Compensation Committee Processes and Procedures for Considering and Determining Executive Compensation in 2021” above and our Compensation Discussion and Analysis beginning on page 41.

Compensation Committee Report

The Compensation Committee has reviewed and discussed the Compensation Discussion and Analysis with management, and based on the review and discussions, recommended to the Board of Directors that the Compensation Discussion and Analysis be included in the

Company’s 2022 Annual Meeting proxy statement and incorporated by reference into the Company’s Annual Report on Form 10-K for the year ended December 31, 2021.

Compensation Committee of the Board of Directors

Robert A. Eckert, Chair

Wanda M. Austin

Brian J. Druker

Greg C. Garland

S. Omar Ishrak

Tyler Jacks

LOGO ï 2022 Proxy Statement39


    

 

 

 

 

Item 2 — Advisory Vote to Approve Our Executive Compensation

 

 

 

 

2019 Executive Compensation Was Aligned With Our Strategy and Performance

As discussed more fully in our Compensation Discussion and Analysis starting on page 38, a significant majority of each NEO’s compensation isat-risk and dependent on our performance and execution of our strategic priorities.

LTI Equity Award Allocation2019 Total Target Direct Compensation Mix

LOGO

LOGO

2019 Performance AgainstPre-Established Goals and MeasuresItem 2

2019 Annual Cash Incentive Program

 

 

2017-2019 Long-Term Incentive Performance Award Payout

 

Goal

 

  

 

Weighting

 

 

 

 

 

% of Target 

Earned 

 

 

LOGO

 

Financial Performance

 

 

Revenues

 

  

 

30%

 

 

 

 

177% 

 

 

Non-GAAP Net Income(1)

 

  

 

30%

 

 

 

 

168% 

 

 

Progress Innovative Pipeline

 

 

Advance Early Pipeline

 

  

 

10%

 

 

 

 

100% 

 

 

Execute Key Clinical Studies and Regulatory Filings

 

  

 

20%

 

 

 

 

80% 

 

 

Deliver Annual Priorities

 

 

Execute Critical Launches

and Long-Term

Commercial Objectives

 

  

 

5%

 

 

 

 

77% 

 

 

Achieve Productivity Objectives

 

  

 

5%

 

 

 

 

107% 

 

 

Final Score

 

  

 

Achieved 138.9% 

 

(1)

Non-GAAP net income for purposes of the 2019 Company performance goals of our annual cash incentive award program is reported and reconciled inAppendix B.

(2)

The operating measures of the 2017-2019 performance goals were based onnon-GAAP financial results for 2017, 2018, and 2019 as reported and reconciled inAppendix B, except that operating measures were further adjusted for the impacts of Hurricane Maria as prescribed by the terms of the 2017-2019 performance goals document. For this purpose, operating expense was reduced by $147 million ($0.16 in EPS) for 2017, increased by $21 million ($0.03 in EPS) for 2018, and increased by $49 million ($0.07 in EPS) for 2019.

LOGOï 2020 Proxy Statement    35


Item 2 — Advisory Vote to Approve Our Executive Compensation

2019 Alignment of Pay with Performance

Our strategy includes a series of integrated activities to strengthen our long-term competitive position in the industry. Key 2019 activities that align our NEO pay with performance and support the execution of our strategic priorities are summarized below.

Our financial performance was strong in a year of transition.

We delivered aone-year total shareholder return, or TSR, of 28%. We outperformed our peer group average for theone-, three-, and five-year TSRs and significantly outperformed the Standard & Poor’s 500 Index for the three-year period.

In March 2019, when we established our 2019 performance goals, we expected to drive volume growth in our newer products, but we also anticipated substantial competition against our legacy products due to patent expiries that would more than offset newer product sales growth. Our early 2019 investor guidance also reflected this anticipated competitive intensity.

In 2019, we grew product volumes by 3% globally. And, despite the anticipated competitive headwinds, we outperformed our budgeted financial targets and exceeded our original guidance as we retained more of our legacy product sales than expected, drove our newer product volume growth, and addedOtezla® to our product portfolio.

Our strong cash flows and balance sheet allowed continued investment for long-term growth in 2019 through internal research and development, capital expenditures, and external business development transactions.

Our quarterly 2019 dividend of $1.45 per share represented a 10% increase from the quarterly dividend for 2018.

In 2019, we returned $11.2 billion to our stockholders in the form of repurchases of our Common Stock ($7.7 billion) and dividends paid ($3.5 billion).

We progressed our pipeline.

We develop innovative and biosimilar medicines that address unmet medical needs to treat serious illnesses.

In 2019, we launchedEVENITY®(1), an innovative product for the treatment of osteoporosis in postmenopausal women at high risk of fracture, and two oncology biosimilars,MVASI®(2) (biosimilar bevacizumab (Avastin®)) andKANJINTI®(2) (biosimilar trastuzumab (Herceptin®)) in the U.S.

We advanced our early pipeline and executed key clinical studies and regulatory filings.

We delivered on our annual priorities.

We executed critical launches and long-term commercial objectives. Our revenues benefited from volume-driven growth from a number of innovative medicines, includingProlia®,Aimovig®(3), andRepatha®.

We achieved our productivity objectives. We realized gross savings of approximately $286 million as a result of our focus on productivity to support continued reinvestment opportunities (such as our early pipeline).

We continued to deliver on our other strategic priorities.

We launched our first product in China and made significant progress in expanding our presence in China and Japan, the second and third largest pharmaceutical markets, respectively.

We successfully operated our next-generation manufacturing facility in Singapore and continued to work on the construction of our U.S facility in Rhode Island.

Positive 2019 Say on Pay Vote Outcome and Engagement With Our Stockholders

In 2019, we received approximately 93% stockholder support on our say on pay advisory vote. In addition to our outreach by our executives and our Investor Relations department to our investors owning approximately 58% of our outstanding shares, since our 2019 annual meeting of stockholders, we have engaged in governance-focused outreach activities and discussions with stockholders comprising approximately 51% of our outstanding shares. The compensation-related feedback is

reviewed by our Compensation and Management Development Committee, or Compensation Committee. In 2019, the predominant feedback from investors with respect to our compensation and governance practices was that they are satisfied with our compensation program and governance practices. For more detail regarding our stockholder engagement, see page 46.

(1)

Jointly developed in collaboration with UCB. Developed in Japan by Amgen Astellas BioPharma K.K., our joint venture with Astellas Pharma Inc.

(2)

Jointly developed in collaboration with Allergan plc.

(3)

Jointly developed in collaboration with Novartis AG.

36    LOGOï 2020 Proxy Statement


Item 2 — Advisory Vote to Approve Our Executive Compensation

Board Recommends a Vote “FOR” Our Executive Compensation

 

 

This advisory stockholder vote, commonly known as “Say on Pay,” gives you, as a stockholder, the opportunity to endorse or not endorse our executive pay program and policies. Accordingly, as required by Section 14A of the Securities and Exchange Act of 1934, as amended, you are being asked to cast an advisory vote on the compensation of our Named Executive Officers, or NEOs, as disclosed in the Compensation Discussion and Analysis (pages 41 through 72) and related compensation tables and the narrative in this proxy statement (pages 73 through 86). We urge stockholders to read the Compensation Discussion and Analysis section of this proxy statement, as well as the related tables and disclosures for a more complete understanding of how our executive compensation program operates.

Our Board of Directors, or Board, believes that the 2021 compensation of our NEOs was appropriate, our current executive compensation program aligns the interests of our executives with those of our stockholders, and compensation outcomes are primarily based on the performance of our Company. We intend that our compensation programs reward actions and outcomes that are consistent with the sound operation of our Company, advance our strategy, and are aligned with the creation of long-term stockholder value.

For thethese reasons and as discussed above and more fully in the Compensation Discussion and Analysis, the Board recommends that stockholders vote “FOR” the following resolution:

“Resolved, that the stockholders approve, on an advisory basis, the compensation paid to the Company’s Named Executive Officers, as

disclosed pursuant to Securities and Exchange Commission rules in the Compensation Discussion and Analysis, the compensation tables and the accompanying narrative disclosure of this proxy statement.”

Although this vote is advisory and is not binding on the Board, our Compensation and Management Development Committee values the opinions expressed by our stockholders and will consider the outcome of the vote when making future executive compensation decisions.

We currently conduct annual advisory votes on executive compensation, and we expect to conduct the next advisory vote on executive compensation at our 20212023 annual meeting of stockholders.

 

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE APPROVAL OF THE ADVISORY RESOLUTION TO APPROVE THE COMPENSATION OF THE COMPANY’S NAMED EXECUTIVE OFFICERS.

 

40    LOGO  ï 2020 Proxy Statement    37


Compensation Discussion and Analysis

Executive Compensation

Compensation Discussion and Analysis

Table of Contents

Our Named Executive Officers

38

Our Strategy

39

Our Compensation and Governance Best Practices

40

Aligning Pay With Performance and Execution of Our Strategic Priorities

41

Positive 2019 Say on Pay Vote Outcome and Engagement With Our Stockholders

46

Long-Term Incentive Equity Award Design in 2019

46

Our 2019 Compensation Program Highlights and Objectives

47

How Compensation Decisions Are Made For Our Named Executive Officers

48

Elements of Compensation and Specific Compensation Decisions

51

Compensation Policies and Practices

61

Non-Direct Compensation and Payouts in Certain Circumstances

63

Taxes and Accounting Standards

65

This Compensation Discussion and Analysis describes our compensation strategy, philosophy, policies, programs, and practices for our Named Executive Officers, or NEOs, and the positions they held in 2019 below.

Our Named Executive Officers

NameTitle

Robert A. Bradway

Chairman of the Board, Chief Executive Officer and President

Murdo Gordon

Executive Vice President, Global Commercial Operations

David W. Meline

Executive Vice President and Chief Financial Officer(1)

David M. Reese

Executive Vice President, Research and Development

Jonathan P. Graham

Executive Vice President, General Counsel and Secretary

(1)

Mr. Meline retired as Chief Financial Officer on December 31, 2019. Peter H. Griffith became Executive Vice President and Chief Financial Officer effective January 1, 2020. As he was not an executive officer in 2019, Mr. Griffith is not considered a Named Executive Officer in this proxy statement.

38    LOGOï 20202022 Proxy Statement


    

 

 

 

 

Compensation Discussion and Analysis

 

 

 

 

 

Executive Compensation

Compensation Discussion and Analysis

Table of Contents

Our Named Executive Officers

41

Our Strategy

41

Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance

43

Our Compensation Best Practices

44

Executing On Our Strategic Priorities While Navigating the Impact of the COVID-19 Pandemic

45

Aligning Pay With Performance

45

Positive 2021 Say on Pay Vote Outcome and Compensation Design Changes in Response to 2021 Stockholder Input

51

Long-Term Incentive Equity Award Design in 2021

52

Our 2021 Compensation Program Highlights and Objectives

53

How Compensation Decisions Are Made For Our Named Executive Officers

54

Elements of Compensation and Specific Compensation Decisions

57

Compensation Policies and Practices

68

Non-Direct Compensation and Payouts in Certain Circumstances

70

Tax and Accounting Standards

72

This Compensation Discussion and Analysis describes our compensation strategy, philosophy, policies, programs, and practices for our Named Executive Officers, or NEOs, and the executive positions they held in 2021 as set forth below.

Our Named Executive Officers

NameTitle

Robert A. Bradway

Chief Executive Officer and President

Murdo Gordon

Executive Vice President, Global Commercial Operations

David M. Reese

Executive Vice President, Research and Development

Peter H. Griffith

Executive Vice President and Chief Financial Officer

Esteban Santos

Executive Vice President, Operations

Our Strategy

 

Our strategy includes a series of integrated activities designed to strengthen our long-term competitive position in the industry. Select 2019 activitySuccessful strategy requires constant rebalancing of resource allocation across the short-, medium- and long-term.

How Our Board Oversees Our Strategy

Our Board of Directors, or Board, possesses a deep and broad set of skills and experiences that supports the executionfacilitate strong oversight of our strategic prioritiesdirection. Annually, our Board engages in a dedicated strategy session focused on a comprehensive review of our strategy and deliverygoals for the business for the short-, medium-, and long-term. The Company’s management is then charged with executing on the business strategy as

informed by the Board’s review. Throughout the course of the year, the Board and its committees receive from management in-depth reviews of key topics and developments for our business and its strategy, reports on our business performance are summarized belowrelative to our strategy, and discussed further in the following pages.our enterprise level risks and risk mitigation activities.

Strategic Priorities

Innovative Medicines

Branded Biosimilars

Transforming Amgen

for the Future

Capital Allocation and Investing for Long-Term Growth

Global Geographic Reach

Next-Generation

Biomanufacturing

DescriptionSelected 2019 Activity

Innovative

Medicines

Innovation is at the core of our strategy. Our focus on developing innovative, “breakaway” medicines to address important unmet needs guides how we allocate resources across internal and external program possibilities. This results in a productive balance of internal development and external programs and collaborations reflected in our current product portfolio and pipeline.

Launched EVENITY®(1) (osteoporosis)

Acquired Otezla® (apremilast)

•  Progressed innovative pipeline:

8 product teams formed(2)

7 first-in-human studies initiated

4 programs advanced throughearly-to-late stage portal(3)

Branded

Biosimilars

We believe our deep experience in biologics development and biotechnology manufacturing position us for leadership in the emerging biosimilars market. Our branded biosimilar medicines have the potential to expand access to important medicines for patients while delivering volume-based sales growth in our therapeutic areas.

•  Launched our first biosimilars in the U.S.:

MVASI®(4)(biosimilar bevacizumab (Avastin®))

KANJINTI®(4) (biosimilar trastuzumab (Herceptin®))

AVSOLA (biosimilar infliximab (Remicade®))approved in U.S.

ABP 798(4) (biosimilar rituximab (Rituxan®))Biologics License Application submitted to U.S. Food and Drug Administration

Transforming

Amgen

for the Future

In 2019, we began realizing the benefit of productivity initiatives embedded in our business. The savings from the productivity initiatives have contributed, and we expect will continue to contribute, to funding strategic growth investments, such as investment in research and development.

Realized gross productivity savings which wereinvested in our business, including in our early oncology research and development programs

��Capital Allocation
and Investing for
Long-Term Growth

Our strong cash flows and balance sheet also allows us to make substantial investments for long-term growth. We also recognize that stockholders who support investment in developing innovative medicines require an appropriate return on the capital they commit to Amgen.

•  Invested $16B for long-term growth:

Acquired Otezla andNuevolution AB

20.5% equity stake in BeiGene Ltd.(5)

•  Returned capital to stockholders:

– $7.7B in stock repurchases

– $3.5B of dividends paid

$1.45 per share per quarter,a 10% per share dividend increase over 2018

Global Geographic

Reach

We are leveraging our global presence to deliver the potential of our products to patients globally. Amgen medicines are now available to patients in approximately 100 countries worldwide (up from 50 in 2011).

•  Launched Repatha® in China

•  Launched EVENITY in Japan

•  Expanded oncology presence in China through strategic collaboration with BeiGene Ltd.

Next-Generation Biomanufacturing

Next-generation biomanufacturing plants have a smaller manufacturing footprint and reduce environmental impact, including reducing consumption of water and energy and lower levels of carbon emissions. Next-generation biomanufacturing plants can be built in less time than traditional plants and have lower operating costs.

•  Singapore next-generation biomanufacturing facility operating and delivering cost and environmental efficiencies

•  Continued work on the construction of our first U.S. next-generation biomanufacturing plant

(1)

Jointly developed in collaboration with UCB. Developed in Japan by Amgen Astellas BioPhrama K.K., our joint venture with Astellas Pharma Inc.

(2)

Formed when a molecule has been judged to have the potential to be safe and effective in humans.

(3)

The period covering Phase 2 through Phase 3.

(4)

Jointly developed in collaboration with Allergan plc.

(5)

Entered into strategic collaboration with BeiGene Ltd. in October 2019; closed in January 2020.

 

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Compensation Discussion and Analysis

 

 

 

 

 

2021 Activities Supporting Execution of Our Strategy

Select 2021 activities that support the execution of our strategic priorities and delivery of performance are summarized below and discussed further in the following pages.

  Strategic Priorities  

Importance

Select 2021 Activities

LOGO

Internal and

External

Innovation

Innovation is at the core of our strategy. Our focus on developing innovative medicines to address important unmet needs guides how we allocate resources across internal and external program possibilities. This results in a productive balance of internal development and external programs and collaborations reflected in our current product portfolio and pipeline.

•  Launched:

–  LUMAKRAS® for the treatment of advanced non-small cell lung cancer;

–  TEZSPIRE(1) for the treatment of severe asthma (based on our December 2021 U.S. Food and Drug Administration, or FDA, approval); and

–  Otezla® for the expanded indication for the treatment of plaque psoriasis across all severities (mild, moderate, and severe).

  Completed strategic business acquisitions that add innovation, including:

–  Five Prime Therapeutics, Inc., and bemarituzumab, a first-in-class antibody in oncology; and

–  Teneobio, Inc. and its proprietary bispecific and multispecific antibody technologies and portfolio of early-stage oncology assets.

  Entered into a collaboration with Kyowa Kirin Co. Ltd. to develop and commercialize AMG 451, a Phase 3-ready first-in-class asset in inflammation.

Executed key clinical studies and advanced innovative first-in-class pipeline delivering positive results:

  Generated data supportive of the approval of LUMAKRAS in the U.S., Canada, and Great Britain, and in the EU from the Committee for Medicinal Products for Human Use, and the submissions of TEZSPIRE and Otezla (across all severities of plaque psoriasis) to the FDA;

  Advanced bemarituzumab into Phase 3;

  Expanded KYPROLIS® U.S. prescribing information to include its use in combination with DARZALEX FASPRO®(2) and dexamethasone for patients with multiple myeloma at first or subsequent relapse; and

Progressed our early innovative pipeline with 7 product teams(3) formed, 4 first-in-human studies initiated, and 4 programs advanced through our early-to-late stage portal.

LOGO

Branded

Biosimilars

Our branded biosimilars are fully integrated with, and supported by, our biologic development, manufacturing and global commercial operations capabilities. We use the same development and manufacturing processes, scientific standards, quality systems, and supply chain for our biosimilars as we do for our innovator biologics. Further, the same global commercial team members who have been talking with providers on our proprietary branded portfolio also represent our branded biosimilars.

  We have 11 biosimilars in our current portfolio, five that have been approved in the U.S., three in the EU, and three in Phase 3 development.

  We have Phase 3 studies underway for:

–  ABP 654 (biosimilar ustekinumab (STELARA®(4)));

–  ABP 938 (biosimilar aflibercept (EYLEA®(5))); and

–  ABP 959 (biosimilar eculizumab (Soliris®(6))).

  In 2021, MVASI® (biosimilar bevacizumab (Avastin®(7))) led the bevacizumab segment in the U.S., KANJINTI® (biosimilar trastuzumab (Herceptin®(7))) was the most purchased trastuzumab in the U.S., and AMGEVITA (biosimilar adalimumab (Humira®(8))) was the most prescribed adalimumab biosimilar in the EU.

LOGO

Global

Impact

We are leveraging our global presence to serve patients and customers globally and international expansion is an important part of our growth strategy. Amgen medicines are available to patients in approximately 100 countries worldwide.

  In fast growing markets in Asia, we continue to expand our presence:

  In China, we received approval for Otezla in mild-to-moderate psoriasis, Repatha® was added to the National Reimbursement Drug List, and we currently have five additional marketed products (XGEVA®, KYPROLIS, BLINCYTO®, Repatha, and Prolia®); and

  In Japan, based on our 2021 filing, we received approval for LUMAKRAS in January 2022, and have five marketed products (BLINCYTO, EVENITY®, Repatha, Aimovig®, and Otezla).

(1)

Being developed in collaboration with AstraZeneca plc.

(2)

DARZALEX FASPRO is a registered trademark of Janssen Biotech, Inc.

(3)

Formed when a molecule has been judged to have the potential to be safe and effective in humans.

(4)

STELARA is a registered trademark of Janssen Biotech, Inc.

(5)

EYLEA is a registered trademark of Regeneron Pharmaceuticals, Inc.

(6)

Soliris is a registered trademark of Alexion Pharmaceuticals, Inc.

(7)

Avastin and Herceptin are registered trademarks of Genentech, Inc.

(8)

Humira is a registered trademark of AbbVie Inc.

42    LOGO ï 2022 Proxy Statement


Compensation Discussion and Analysis

  Strategic Priorities  

Importance

Select 2021 Activities

LOGO

Manufacturing

Excellence

Smaller footprint, highly resource efficient biomanufacturing plants reduce environmental impact, including reducing consumption of water and energy and lower levels of carbon emissions. They also can be built in less time than traditional plants and have lower operating costs.

  Our latest U.S. biomanufacturing plant featuring innovative technologies in Rhode Island received FDA approval in January 2022, expanding our manufacturing capacity while also delivering environmental and cost efficiencies.

  We announced plans to invest approximately $1B to build two additional U.S. plants (in Ohio and North Carolina) featuring innovative technologies that support our 2027 environmental targets (including carbon neutrality(1)), and that will bring hundreds of jobs to the regions and expand our access to diverse talent.

LOGO

Continuous

Improvement

We prioritize continuous operating improvements to fund innovation. We have embarked on a digital transformation journey to advance modalities and technology platforms and our better understanding of biology to work to achieve maximum efficiencies and drive innovation.

  We invested in information technology platforms, and established a Company-wide digital transformationgoal to focus on process simplification, automation,andinnovation to further enable speed andefficiencies in our research, development, and global commercial operations.

LOGO

Return of Capital

Our strong cash flows and balance sheet allow us to make substantial investments for long-term growth. We also recognize that stockholders who support investment in developing innovative medicines require an appropriate return on the capital they commit to Amgen.

Invested in excess of $8.2B for long-term growth:

–  $4.8B in research and development;

  $2.5Bin acquisitions; and

  $880Mincapital expenditures, including investments in manufacturing sites that support our environmental goals.

•  Returned $9 billion of capital to stockholders:

–  $4B of dividends paid ($1.76 per share per quarter, a 10% per share dividend increase over 2020); and

  $5B  in share repurchases.

Our Approach to Environmental Sustainability, Social Responsibility, and Corporate Governance

Consistent with our commitment to the long-term and our mission to serve patients, we are focused on building a sustainable business. To that end, our environmental sustainability, social responsibility, and corporate governance (ESG) activities are integrated into our execution of our strategic priorities and our business pursuits and overseen by our Board.

Our 2027 environmental sustainability plan features ambitious targets on carbon emissions, water conservation and waste reductions. The plan, our third since 2007, includes a goal of achieving carbon neutrality(1) in our operations by 2027. The plan also includes goals to reduce water use by 40% and waste disposed by 75%.(1) To build the infrastructure to support achievement of our 2027 environmental sustainability plan and further embed diversity, a sense of belonging, and inclusion into our culture, in March 2021, our Compensation and Management Development Committee, or Compensation Committee, added an ESG goal to our 2021 Company performance goals for our annual cash incentive plan focused on two areas: an environmental goal and social responsibility goal.

The environmental goal required development of annual auditable conservation targets, governance bodies, teams, and processes to oversee activities to deliver on such targets.

The social responsibility goal required development of action plans by leaders at executive director levels and above to establish, document, and execute diversity, inclusion, and belonging action plans in 2021 to continue to enhance the diversity and inclusivity of our culture.

For additional discussion, please see “Aligning Pay With Performance” and “Executing on Our Strategic Priorities While Navigating the Impact of the COVID-19 Pandemic—2021 Annual Cash Incentive Plan,” and “Elements of Compensation and Specific Compensation Decisions—Annual Cash Incentive Awards—2021 Company Performance Goals” below. A full description of our ESG efforts can be found in the “Corporate Governance” section, including the subsection “—Our Approach to Environmental Sustainability, Social Responsibility, and Human Capital Management.”

(1)

Carbon neutrality goal refers to Scope 1 and 2. Reductions take into account only verified reduction projections, do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

LOGO ï 2022 Proxy Statement43


Compensation Discussion and Analysis

Our Compensation and Governance Best Practices

 

What we do

 

 

 

Majority of compensation is performance based: A substantial majority of NEO compensation is performance based andat-risk.

 

 

Recoupment: Our incentive compensation plans contain recoupment provisions applicable to all staff members that expressly allow the Compensation and Management Development Committee, or Compensation Committee, to determine that annual cash incentive awards are not earned fully or in part where such employee has engaged in misconduct that causes serious financial or reputational damage to the Company.

Clawback policy:Policy:Our Board of Directors, or Board is required to consider the recapture of past cash or long-term incentive, or LTI, equity award payouts to our NEOs if the amounts were determined based on financial results that are later restated and the NEOs’ misconduct is determined by the Board to have caused the restatement.

Recoupment Provisions for Misconduct: Our recoupment mechanisms include:

Cash Incentive Compensation Plan Recoupment Provisions: Recoupment provisions applicable to all staff members that expressly allow the Compensation Committee to determine that annual cash incentive awards are not earned fully, or in part, where such employee has engaged in misconduct that causes serious financial or reputational damage to the Company.

Equity Recoupment Policy: The Compensation Committee has adopted a policy that provides the Compensation Committee with the ability to cause the forfeiture and cancellation of unvested equity awards and any unexercised portion of any stock options (granted after December 31, 2020) should an executive officer be terminated for engaging in misconduct that caused serious financial or reputational damage to the Company.

 

 

Robust stock ownership and retention guidelines: We have a six times base salary ownership requirement for our Chief Executive Officer, or CEO. Our Executive Vice Presidents and Senior Vice Presidents have three times and two times base salary ownership requirements, respectively. Officers are required to hold shares of our Common Stock acquired through the vesting of restricted stock units, or RSUs, the payout of performance units, or the exercise of stock options until they have reached the required stock ownership level. Compliance with this policy is assessed annually and all executive officers, including our NEOs, who were expected to meet such guidelines by December 31, 2019,2021, were in compliance.

 

 

Minimum vesting periods: Our equity incentive plan provides that our equity awards are subject to a minimum vesting period of no less than one year onfor 95% of equity awards granted and ourgranted. Our grants generally vest over four years, with no vesting in the first year and vesting in three approximately equal annual installments on the second, third, and fourth anniversaries of the grant date.

 

 

Performance-based equity: Our LTI equity award grants are primarily (80%) performance-based, with 50% in the form of three-year performance units.

 

 

Independent compensation consultant: The Compensation Committee retained and sought advice from Frederic W. Cook & Co., or FW Cook, to assist the Compensation Committee in its review and determination of executive compensation.

 

 

Amgen Values:The Amgen Values overlay our Company performance goals and the Compensation Committee assesses each NEO’s annual compensation, including the annual incentive award, based on compliance with these internal standards.

EEO-1 Disclosure: To enhance transparency around the composition of our workforce, we disclose our annual Consolidated EEO-1 Report(1) after our submission of the report to the U.S. Equal Employment Opportunity Commission.

 

What we don’t do

 

 

×

No alterations to our established goals to respond to changing business conditions (for example, we have not made any changes to established goals in response to the occurrence or challenges of the pandemic).

×

 

No hedging or pledging: With respect to our Common Stock, all of our staff members and Board members are prohibited from engaging in short sales, purchasing or pledging our Common Stock on margin(2), or entering into any hedging, derivative, or similar transactions.

 

×

 

Nore-pricing or backdating:We have strong LTI equity award plans and policies that prohibitre-pricing or backdating of equity awards.

 

×

 

No taxgross-ups: We do not provide taxgross-ups, except for business-related payments such as reimbursement of certain relocation expenses on behalf of newly hired and current executives who agree to relocate to work on the Company’s behalf.

 

×

 

No single-trigger and nogross-ups in the event of a change of control: We do not have “single-trigger” equity vesting acceleration upon a change of control for RSUs and stock options and do not provide taxgross-ups on change of control payments.

 

×

 

No excessive perks:Our perquisites are limited to those with a clear business-related rationale.

 

×

 

No employment agreements: We do not have employment contracts or guaranteed bonuses, other than in countries where they are required by law.

 

×

 

No dividends paid on unvested equity: Dividends equivalents accrue on our performance units and RSUs, but are paid out in shares of our Common Stock only when, and to the extent that, the underlying award is earned and vested. Stock options do not have dividend equivalent rights.

 

×

 

No defined benefit pension or supplemental executive retirement plan (SERP) benefits or “above market” interest on deferred compensation.

 

 

(1)

Beginning with our Consolidated EEO-1 Report filed in 2021.

(2)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

 

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Compensation Discussion and Analysis

 

 

 

 

 

Executing on Our Strategic Priorities While Navigating the Impact of the COVID-19 Pandemic

Ongoing Impact of the COVID-19 Pandemic

Since the onset of the pandemic in 2020, we have remained focused on our strategic priorities and our values while closely managing the effects of the COVID-19 pandemic on our global operations. We continue to take appropriate steps to minimize risks to our employees, a significant number of whom have continued to work virtually. Staff member access to our facilities has been in accordance with applicable government health and safety protocols and guidance issued in response to the COVID-19 pandemic and in 2021 we required staff members in the U.S. and Puerto Rico to be fully vaccinated against COVID-19.(1)To date, our remote working arrangements have not significantly affected our ability to maintain critical business operations, and we have not experienced disruptions to or shortages of our supply of medicines.

Since the beginning of the pandemic, we have seen changes in patient visits to doctors’ offices that have impacted providing treatments to existing patients and reduced diagnoses in new patients. Through 2021, while there has been gradual recovery in both patient visits and diagnoses, overall these have remained below pre-COVID levels. The cumulative decrease in diagnoses over the course of the pandemic has suppressed the volume of new patients starting treatment, impacting our revenues and business for 2021. We are closely monitoring the effects of the emerging COVID-19 variants on patient behavior and access.

With respect to our drug development activities, we are continuously monitoring COVID-19 infection rates, including change from new variants, and working to mitigate effects on future study enrollment in our clinical trials and evaluating the impact in all countries where clinical trials occur. We remain focused on supporting our active clinical sites in their providing care for patients and in our providing investigational drug supply.

Amgen’s Response to the COVID-19 Pandemic

As a leading global healthcare company and responsible corporate citizen, in 2021 we prioritized:

   Ensuring the safety and well-being of our employees around the world;

   Contributing to the fight against COVID-19, including manufacturing COVID-19 antibody material with Eli Lilly & Company;

   Continuing to serve patients – both those currently on Amgen medicines and those who stand to benefit from potential new medicines in our pipeline; and

   Helping in the communities where we live and work.

We established the goals for our annual cash incentive award and LTI equity award programs in March 2021. Since then, we have not made any changes to these goals in response to the challenges of the pandemic.

Aligning Pay With Performance and Execution of Our Strategic Priorities

 

 

A substantial majority of each NEO’s compensation is “at risk” and earned based on our execution of our strategy and performance. Our annual cash and long-term equity incentive programs promote focus on activities supporting the execution of our strategic priorities as well as near- andnear-and long-term stockholder value creation. This incentivecreation with compensation is earned based on our financial, operating, and stock price performance. In 2019, we made significant progress

Our Executive Compensation Objectives

Our executive compensation program is designed to achieve the following objectives:

Pay for performance in a manner that strongly aligns with stockholder interests by rewarding both our short- and long-term performance.

Drive our business strategy by positioning our staff to execute on our strategic priorities in the near- and longer-term.

Attract, motivate, and retain the highest level of talent by providing competitive compensation, consistent with their roles and responsibilities, our success, and their contributions to this success.

Mitigate compensation risk by maintaining pay practices that reward actions and outcomes consistent with the sound operation of our Company and with the creation of long-term stockholder value.

Consider all Amgen staff members in the design of our executive compensation programs, to ensure a consistent approach that encourages and rewards all staff members who contribute to our success.

Our 2021 Performance

Despite the ongoing impact of the pandemic, we have delivered strong performance goalsin 2021. We advanced our innovative pipeline, launched new products, completed several strategic transactions to augment our pipeline and research capabilities, and continued to provide uninterrupted supply of our medicines globally. We accomplished these objectives while maintaining a strategic and disciplined approach to capital allocation and advancing our strategic priorities, facilitating execution of our strategy and mission to serve patients.ESG efforts.

We delivered a one year total shareholder return, or TSR, of 28%. As depicted below, we outperformed our peer group average TSR for each of the

(1)

This vaccination requirement did not apply to staff who were unable to receive a COVID-19 vaccine because of qualifying medical or religious reasons.

LOGO one-,ï three-, and five-year periods, and strongly outperformed the Standard and Poor’s 500 Index, or S&P 500, TSR for the three-year period. 2022 Proxy Statement45


Compensation Discussion and Analysis

 

 

LOGO

LOGOLOGO

Our strong cash flows and balance sheet allowed continuedfor significant investment in 2021 for long-term growth in 2019 through internal research and development, strategic business acquisitions and collaborations, and capital expenditures, and external business development transactions (including the acquisition of Otezla and our equity stake in BeiGene),projects, while simultaneously providing substantial returns to stockholders.

 

Otezla Acquisition.The acquisitionIn 2021, while investing $4.8 billion in research and development, $2.5 billion in strategic business acquisitions, and $880 million in capital projects, we also returned $9 billion of Otezla, the only oralnon-biologic treatment for psoriasiscapital to our stockholders ($4 billion of dividends and psoriatic arthritis, offers many benefits, including:$5 billion in share repurchases).

-

A strong strategic fit with our long-standing expertise in psoriasis and inflammation;

-

A differentiated, oral therapy complementary to our existing inflammation franchise of innovative biologics and biosimilar products; and

-

Worldwide rights enhancing our global geographic expansion objectives.

BeiGene Ltd. Equity Stake.To support the development of our early oncology pipeline and our global geographic expansion objectives, we entered into a collaboration with BeiGene, a research-based, oncology-focused biotechnology company with an established, experienced team in China, the world’s second-largest pharmaceutical market. BeiGene will commercialize three of our products in China (XGEVA®, KYPROLIS®, and BLINCYTO®) and we and BeiGene will collaborate to advance 20 medicines from our innovative oncology pipeline in China and globally. In support of this collaboration, we took a 20.5% equity stake in BeiGene.

In 2019, whileinvesting $4.1 billion in research and development,$618 million in capital expenditures, and$13.6 billion in acquisitions, we also allocated$11.2 billion of capital for return to our stockholders ($7.7 billion in stock repurchases and $3.5 billion of dividends)

We increased our quarterly dividend per share 10% over 20182020 (to $1.45$1.76 per share per quarter for 2019)2021). Our annualized dividend per share has increased 418%529% since the inception of our dividend in 2011.

Annual Dividend Increases

 

 

LOGOLOGO

Depicted below is our one-year, three-year, five-year, and 10-year total shareholder return, or TSR, for the period ending December 31, 2021. As shown, we delivered long-term shareholder value and returns with ten-year TSR of 348%, outperforming our peer group in this period.

Total Shareholder Return

 

LOGOï 2020 Proxy Statement    41

LOGO

2021 Annual Cash Incentive Plan


 

Compensation DiscussionEarned amounts from our 2021 annual cash incentive plan are tied directly to our performance based on pre-established financial and Analysisoperating performance goals designed to drive execution of our strategic priorities.

 

 

Earned amounts from our 2019 annual cash incentive compensation program are tied directly to our performance based onpre-established financial and operating performance goals designed to drive execution of our strategic priorities.

Goal

 

   

 

Weighting

 

 

 

 

 

% of Target Earned

 

 

1. Financial Performance

 

Revenues

Target  $22.1B

Results $23.4B

 

  

 

 

 

 

30%

 

 

 

 

 

 

177%

 

 

Non-GAAP Net Income(1)

Target  $8.2B

Results $9.0B

 

  

 

 

 

 

30%

 

 

 

 

 

 

168%

 

 

 

2. Progress Innovative Pipeline

 

 

Advance Early Pipeline

 

  

 

 

 

10%

 

 

 

 

100%

 

Execute Key Clinical Studies and Regulatory Filings

 

  

 

 

 

 

20%

 

 

 

 

 

 

80%

 

 

 

3. Deliver Annual Priorities

 

 

Execute Critical Launches and Long-Term Commercial Objectives

 

  

 

 

 

 

5%

 

 

 

 

 

 

77%

 

 

Achieve Productivity Objectives

 

  

 

 

 

 

5%

 

 

 

 

 

 

107%

 

  

 

Final Score

 

  

 

 

 

 

Achieved 138.9%

 

Goal  Weighting   % of
Target
Earned
  Weighted
Score
Achieved(1)
  
1. Financial Performance

 

 62.1%
  

a.  Revenues

    Target $26.227B

    Results $25.979B

   30%    87.6%   
  

b.  Non-GAAP Net Income(2)

    Target $9.515B

    Results $9.797B

   30%    119.5%   
  
2. Progress Innovative Pipeline

 

 53.6%
  

a.  Advance Early Pipeline

   10%    200.0%   
  

b.  Execute Key Clinical Studies and Regulatory Filings

   20%    167.9%   
  
3. Deliver Annual Priorities

 

 21.0%
  

a.  Environmental, Social, and Governance

   5%    195.8%   
  

b.  Digital Transformation

   5%    225.0%   
   
    Final Score        136.8%

1. Our financialWe delivered strong performance was strong in a year of transition.

In March 2019, when we established our 2019 performance goals, we expected to drive volume growth in our newer products, but we also anticipated substantial competition against our legacy products due to patent expiries that would more than offset newer product sales growth. Our early 2019 investor guidance also reflected this anticipated competitive intensity.

In 2019, we grew product volumes by 3% globally. And, despitewhile navigating the anticipated competitive headwinds, we outperformed our budgeted financial targets and exceeded our original guidance as we retained more of our legacy product sales than expected, drove our newer product volume growth, and added Otezla to our product portfolio.

Our 2019 revenues benefited from volume-driven growth from a number of our newer innovative medicines that grew units double digit or better, including Repatha®, Parsabiv®, BLINCYTO, Aimovig®(2), and Prolia®. Overall 2019 revenues decreased 2% to $23.4 billion reflecting

theongoing impact of biosimilar and generic competition against our mature products. Lower product sales were affected by lower net selling price, offset partially by higher unit demand.

Ournon-GAAP net income performance also benefited from our success in retaining more of our mature product sales, driving unit growth of our newer products, and the favorable productivity savings resulting from our strong performance of our “Achieve Productivity Objectives” annual goal discussed further below.

2. We progressed our pipeline(3).pandemic.

 

2019 Pipeline Launches.(a) Revenues and (b) non-GAAP net income

LOGO

   We launched EVENITY, an innovative product for the treatment of osteoporosis in postmenopausal women at high risk of fracture, in the U.S., Canada, Japan, South Korea, and Australia(4).

LOGO

   We also launched two oncology biosimilars in the U.S.:

-MVASI(biosimilar bevacizumab (Avastin®)), the first oncology therapeutic biosimilar approved by the U.S. Food and Drug Administration, or FDA, was approved for all approved indications of Avastin.

-KANJINTI (biosimilar trastuzumab (Herceptin®)) was approved for all approved indications of Herceptin.

In 2019,Despite the ongoing impact of the pandemic, we advancedhave delivered strong performance in 2021. Our rigorous revenue goal was established based on our guidance issued in early 2021 (between $25.8 and $26.6 billion) with our target goal exceeding our 2020 actual revenues. However, the cumulative decrease in patient visits and diagnoses over the course of the pandemic has suppressed the number of new patients starting treatment during 2020, affecting 2021 sales growth. Further, through 2021, while there has been gradual recovery in both patient visits and diagnoses, overall these have remained below pre-COVID levels. As a consequence, we did not achieve target performance for our revenue goal.

Our non-GAAP net income target was correlated to the midpoint of our early pipeline2021 non-GAAP EPS guidance and executed key clinical studiesincluded increased research and regulatory filings.

We generated eight new product teams (formed whendevelopment investment to support our longer-term performance. However, as a molecule has been judged to have the potential to be safe and effective in humans).

We initiated sevenfirst-in-human studies.

We advanced four programs through theearly-to-late stage portal (the period covering Phase 2 through Phase 3).

Oncology:

We advancedresult of, among other things, ourearly oncology programs with approximately 17 individual therapeutics in development.Early data readouts from disciplined operating expense management, we exceeded this pipeline have been promising, including forAMG 510target.

 

 

(1) 

Percentages do not total to final score due to rounding.

(2)

Non-Generally Accepted Accounting Principles, ornon-GAAP, net income for purposes of the 20192021 Company performance goals of our annual cash incentive award programplan is reported and reconciled inAppendix B.

(2)

Jointly developed in collaboration with Novartis AG.

(3)

For complete information regarding our significant pipeline advancements, please refer to ourForm 10-K for the year ended December 31, 2019.

(4)

EVENITY is also approved in Japan and South Korea for men at high risk for fracture and in Australia as a treatment to increase bone mass in men with osteoporosis at high risk of fracture.

 

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Compensation Discussion and Analysis

 

 

 

 

 

(our KRASG12C small molecule inhibitor being investigated as a treatment for a variety of solid tumors):

2. We progressed our pipeline(1)while navigating the ongoing impact of the pandemic.

a. Early pipeline

While monitoring and actively managing the challenges of the impact of COVID-19 to our clinical trials activities discussed earlier, we advanced our early pipeline:

We generated seven new product teams (formed when a molecule has been judged to have the potential to be safe and effective in humans), including for product candidates being studied in oncology, cardiovascular disease, and inflammation.

We initiated four first-in-human studies, including for product candidates being studied in solid tumors (including non-small cell lung cancer, mesothelioma, pancreatic cancer, and ovarian cancer), neuroendocrine prostate cancer, nonalcoholic steatohepatitis (NASH), and multiple myeloma.

We advanced four programs in our early-to-late portal or commit to registrational studies portal.

b. Key clinical studies and regulatory filings

Despite the ongoing impact of the pandemic, we made progress on our key clinical studies and regulatory filings in 2021.

 

-

The FDA grantedOrphan Drug DesignationOncology: for previously treated metastaticnon-small cell lung cancer, or NSCLC, and colorectal cancer with KRASG12C mutation andFast Track Designation for previously treated metastatic NSCLC with KRASG12C mutation.

-

We enrolled a potentially pivotal Phase 2 monotherapy study in advanced NSCLC, and began enrollment of colorectal cancer patients in a Phase 2 monotherapy study.

 

 

We submittedBased on our successful execution of our Phase 2 CodeBreaK 100 study in adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), we launched LUMAKRAS in the U.S. and received regulatory approvals in many countries, including Canada, Great Britain, Switzerland, and United Arab Emirates. Additionally, in January 2022, LUMAKRAS was approved in Japan and we received a conditional marketing authorization for LUMYKRAS in the EU from the Committee for Medicinal Products for Human Use. The CodeBreaK clinical development program is the most advanced program designed to treat patients with an FDA Biologics License Applicationadvanced solid tumor with the KRAS G12C mutation and address the longstanding unmet medical need created by these cancers. Also as part of this program, in 2021, we initiated our Phase 3 study comparing LUMAKRAS to docetaxel in patients with KRAS G12C-mutated advanced NSCLC, Phase 2 study for patients with NSCLC STK11-mutated and/or ABP 798PD-L1 (biosimilar rituximab (Rituxan®)).negative tumors, Phase 2 study in patients with KRAS G12C-mutated solid tumors (other than NSCLC and colorectal cancer), and continued to progress our exploration of LUMAKRAS in multiple Phase 1b combination cohorts.

 

In connection with our 2021 acquisition of Five Prime Therapeutics, we acquired marketed oncology therapeuticsbemarituzumab, we invested in studies that expanded treatment options for patients:a first-in-class anti-fibroblast growth

 - 

For KYPROLIS (our medicinefactor receptor 2b (FGFR2b) antibody for the treatment of patients with relapsed or refractory multiple myeloma),human epidermal growth factor receptor 2 negative FGFR2b-positive gastric and gastroesophageal junction cancer. Bemarituzmab was granted Breakthrough Therapy Designation(2) by the FDA and, based on this designation, we accelerated our Phase 3 CANDOR(1)study (evaluating KYPROLISdevelopment to bring this potential new therapy to patients. We are also investigating bemarituzumab in combination with dexamethasone and DARZALEX® compared to KYPROLIS and dexamethasone alone) met its primary endpoint of progression-free survival.

-

Nplate®(our medicine to treat low blood platelet count) was approved for earlier use in adults with immune thrombocytopenia; and

-

BLINCYTO (our medicine for patients with acute lymphoblastic leukemia) was approved for patients with Philadelphia chromosome negative minimal residual disease-positiveB-cell precursor acute lymphoblastic leukemia in the European Union.other solid tumors, including squamous cell NSCLC.

 

Our 2021 acquisition of Cardiovascular Disease:Teneobio, that includes a Phase 1 bispecific antibody for patients with advanced prostate cancer, proprietary bispecific and multispecific antibody technologies, and a portfolio of early-stage oncology assets, meaningfully adds to our pipeline capabilities in the oncology therapeutic area.

We launchedRepatha® in China as the first PCSK9 inhibitor for adults with established atherosclerotic cardiovascular disease to reduce the risk of myocardial infarction, stroke, and coronary revascularization.

 

In December 2021, the FDA approved the expansion of Inflammatory Disease:KYPROLIS U.S. prescribing information to include its use in combination with DARZALEX FASPRO and dexamethasone for patients with multiple myeloma at first or subsequent relapse.

 

Received aBreakthrough Therapy designationInflammation: forTezepelumab(2) (our medicine in Phase 3 development for asthma) in patients with severe asthma without an eosinophilic phenotype.

 

 

TheBased on results from the PATHFINDER clinical trial program, including results from the successful NAVIGATOR Phase 3 trial, TEZSPIRE (a first-in-class therapy that blocks the action of a cytokine that plays a key role across the spectrum of asthma inflammation developed in collaboration with AstraZeneca) is the only biologic approved by the FDA approvedAVSOLA (biosimilar infliximab (Remicade®))(December 2021) for all approved indicationssevere asthma with no phenotype or biomarker limitations. Additionally, for TEZSPIRE in 2021, we initiated a Phase 3 study in patients with chronic rhinosinusitis with nasal polyps, a Phase 2b study for patients with chronic spontaneous uricaria, and Phase 2 study for patients with chronic obstructive pulmonary disease. TEZSPIRE was granted Orphan Drug Designation(3) by the FDA for the treatment of Remicade.eosinophilic esophagitis.

 

For Bone Health:Otezla

Received approval forEVENITY in the European Union(our medicine approved for the treatment of severe osteoporosismoderate-to-severe plaque psoriasis in postmenopausal women at high risk of fracture.

3. We deliveredthe U.S.), based on our annual priorities.successful execution of the ADVANCE study, at the end of 2021 we received a label expansion from the FDA that allows Otezla to be used in the treatment of plaque psoriasis across all severities (including mild, moderate, and severe).

 

We executed on our critical launchesentered into a collaboration with Kyowa Kirin Co. Ltd. to develop and long-term commercial objectives.commercialize AMG 451

As discussed above, our revenues benefited from volume-driven growth from, a numberPhase 3-ready first-in-class asset in development for the treatment of our newer innovative medicines, including those medicines that were the focus of our annual priorities to execute critical launches:

Prolia(our medicine for patients with osteoporosis) worldwide sales increased 17% in 2019.

Aimovigworldwide sales increased 157%atopic dermatitis, with potential in 2019.other autoimmune diseases.

 

RepathaABP 654 (biosimilar ustekinumab (STELARA)), a monoclonal antibody that inhibits IL-12 worldwide sales increased 20% in 2019. Given the gravity of the impact of cardiovascular disease, we took significant actions to address access challenges for patients who would benefit from Repatha, including:and IL-23, advanced into Phase 3 development.

-

Efforts to Improve Access.To address access challenges, we have offered payers significant rebates on Repatha in exchange for improved patient access.

-

Action to Increase Affordability.In the U.S. we established a 60% lower list price to address affordability for patients, particularly those on Medicare. Beginning January 2020, Repatha is available exclusively at this 60% lower list price.

We achieved our productivity objectives.

LOGO

We began realizing the benefit of the productivity initiatives embedded in our business. In 2019, as a result of our focus on productivity to support continued reinvestment opportunities, we achieved gross savings of approximately $286 million. Part of these savings have been invested into our research and development activities. We expect savings from these productivity initiatives will continue to contribute to funding strategic growth investments, such as investment in our early oncology programs.

We delivered on additional strategic priorities.

LOGO

In 2019, in addition to launching Repatha as our first product in China, we made significant progress in expanding our presence in China and Japan, the second and third largest pharmaceutical markets, respectively.

 

 

(1)

Carfilzomib, Daratumumab and DexamethasoneFor information regarding our significant pipeline advancements, please refer to our Form 10-K for Patients With Relapsed and/or Refractory Multiple Myeloma.the year ended December 31, 2021.

(2)

Jointly developed in collaboration with AstraZeneca plc.A Breakthrough Therapy Designation is designed to expedite the development and regulatory review of medicines that may demonstrate substantial improvement on a clinically significant endpoint over available medicines.

(3)

The Orphan Drug Designation program provides orphan status to drugs and biologics intended for the treatment, prevention, or diagnosis of a rare disease or condition.

 

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Compensation Discussion and Analysis

 

 

 

 

 

Cardiovascular:

We entered intoFor Olpasiran (AMG 890, a strategic collaboration with BeiGene Ltd. to collaboratesmall interfering RNA (siRNA) that lowers lipoprotein(a) being investigated for the treatment of atherosclerotic cardiovascular disease), we executed on the commercialization of XGEVA, KYPROLIS, and BLINCYTO in China and the global development and commercialization of 20 Amgen oncology pipeline products.key clinical milestones for a Phase 2b study.

 

With EVENITY,For Repatha (our medicine approved to help patients lower bad cholesterol and reduce their risks of heart attack and stroke), we realizedexecuted on key clinical milestones for VESALIUS-CV, a large Phase 3 cardiovascular outcomes study of patients with high cardiovascular risk without prior myocardial infarction or stroke.

3. We delivered on our third product approval in three years in Japan through our Amgen Astellas BioPharma K.K. joint venture.

We executed our first biosimilar launch in the Asia-Pacific region with the launch of MVASI in Thailand. This was also the fourth biosimilar launch for Amgen globally.

We acquired Otezla, with approvals around the world, providing an attractive international growth opportunity.

LOGO

In 2019, we successfully operated our next-generation manufacturing facility in Singapore and continued to work on the construction of our U.S. facility in Rhode Island.annual priorities.

 

a. We successfully delivered on our environmental, social, and governance goal.

To support our environmental sustainability 2027 targets, we established a Company-wide environmental goal to develop additional processes and capabilities in this area and successfully delivered, on an accelerated basis, the following tools, governance, and resources:

Annual auditable and verifiable conservation targets for the years 2021-2027;

Governance bodies and processes approved and established to oversee, develop, execute, and monitor these annual targets; and

Teams assembled and operating in accordance with charters approved by the governance bodies to further support activities necessary to achieve the conservation targets.

Our Environmental Sustainability 2027 Targets

  Achieve carbon neutrality;(1)

  Reduce water consumed by 40%;(1) and

  Reduce waste disposed by 75%.(1)

To tangibly deepen and drive the Company’s diversity, inclusion and belonging activities enterprise-wide and actively communicate our culture of belonging to all staff, we established a diversity, inclusion, and belonging goal for all leaders at executive director levels and above to establish, document, and execute diversity, inclusion, and belonging action plans and over 80% of our leaders delivered and executed on such plans in 2021.

b. We successfully achieved our digital transformation goal.

To drive further efficiencies and speed throughout the drug discovery, development, manufacturing, and marketing efforts, we established a digital transformation goal to leverage digitization across our infrastructure and operations. For 2021, each function was challenged to establish digital value creation roadmaps to navigate and monitor the progress of its

digital transformation journey to support greater efficiency and speed in its activities and operations. Eight value creation roadmaps across our operations were established in 2021 with governance activities to simplify and automate our approach to our business as we work towards achieving maximum effectiveness and enable speed.

We delivered on additional strategic priorities.

LOGO

 

   We have successfully operated our manufacturing facility employing a smaller footprint and  reduced  environmental  impact

in Singapore since its licensure in 2017. This success, along with U.S. corporation tax incentives to invest in innovation and advanced technologies, led to our building a second such plant in the U.S. in Rhode Island. These biomanufacturing plants have a smaller manufacturing footprint and reduce environmental impact, including reducing consumption of water and energy and lower levels of carbon emissions. They also can be built in less time than traditional plants and have lower operating costs.

U.S. Biomanufacturing Facility. Our Rhode Island Facility.In 2019, to support expected product volume growth, we continued construction on our first U.S. next-generation biomanufacturing plant, approved by the FDA in Rhode Island. This new plant will be the first of its kind in the U.S., is anticipated to createJanuary 2022, employs our innovative technologies, and creates a substantial number of additional highly skilled manufacturing positions in the U.S., This plant expands our capacity to support volume growth, while also delivering environmental and cost efficiencies.

Investment in Two Additional U.S. Facilities. In 2021, we announced our plans to invest approximately $1 billion to build two new environmentally friendly U.S. facilities to meet the demands for our medicines.

Product assembly and packaging plant in Ohio and multi-product drug substance manufacturing plant in North Carolina.

Both facilities will employutilize cutting edge technologies to be much more efficient and environmentally friendly than traditional plants, supporting our next-generation biomanufacturing2027 carbon neutrality targets. We expect to bring hundreds of full-time jobs to these regions while expanding our access to diverse talent.

LOGO

   Our branded biosimilars are fully integrated with, and supported by, our biologic development, manufacturing and global commercial operations capabilities.

 

We use the same development and manufacturing processes, scientific standards, quality systems, and supply chain for our biosimilars as we do for our innovator biologics.

The same global commercial team members who have been talking with providers on our proprietary branded portfolio also represent our branded biosimilars beginning at launch and are able to help providers and patients with the transition from a branded product to a biosimilar.

(1)

Carbon neutrality goal refers to Scope 1 and 2 emissions. Reductions take into account only verified reduction projections, and do not take into account changes associated with the contraction or expansion of the Company and are measured against a 2019 baseline.

48    LOGO ï 2022 Proxy Statement


Compensation Discussion and Analysis

With our high quality branded biosimilars, we provide expanded access to important medicines for patients, offering more affordable options, and deliver volume-based sales in our therapeutic areas.

We have 11 biosimilars in our current portfolio, five that have been approved in the U.S., three in the EU, and three in Phase 3 development.

Performance Under Our Long-Term Incentive Program

Pay delivery from ourOur LTI compensation plan is tied directly to our stock performance and key annual operational metrics and aligns with long-term value creation for our stockholders.

80% of our annual LTI equity award grants are performance-based, aligning compensation with long-term value creation for our

stockholders. Three-year performancePerformance units comprise 50% of our annual LTI equity award grants. The goal design and all measurement targets are established at the beginning of theeach three-year performance period and, for the 2017-20192019-2021 performance period, were earned based on our performance as measured against thesepre-established annual targets for the three equally weightednon-GAAP operating measures of earnings per share, or EPS, growth operating margin, and operating expense (in 2017 and 2018) and EPS growth, operating margin, and return on invested capital, or ROIC, (for 2019). Thesewith a TSR modifier of +non-GAAP/-30 operating measurespercentage points. ROIC was included as a

measure and rigorous targets were chosenset to drivereflect our ongoing focus on remaining operationally disciplined in our management of our capital. However, during this performance in alignment with,period, we took advantage of several important acquisition opportunities, including Otezla, Five Prime Therapeutics, and focus our executivesTeneobio, that we believed were important to the support of the Company’s business and longer-term performance, but that would have an impact on our 2014-2018 investor commitments, which includedROIC for this performance period. As a consequence, despite our strong three-year average EPS growth operating margin improvement, and operating expense reduction through significant transformation improvement efforts. For the third year of the 2017-2019 performance period (2019), the Compensation Committee replacednon-GAAP operating expense withnon-GAAP ROIC in response to stockholder feedback, as well as our goal of delivering an efficient disciplined business model beyond 2018. At(112.4%) at the end of the 2017-20192019-2021 performance period, our performance under the three annualROIC operating measure percentagesperformance was below target (70.8%) and, when both measures were averaged, resulting inthe result was a total operating measures score of 103.7% driven by our strongnon-GAAP EPS growth over the period.91.6%.

The total operating measures score was then increased or decreased based on our relativeTarget TSR performance as compared to the companies in the S&P 500 over the three-year performance period is set at the 50th percentile relative to the Standard & Poor’s 500 Index, or S&P 500. For relative TSR performance below the 50th percentile, there is a reduction in the total percentage of performance units earned for the performance period. Our strong TSR performance ranking (77.8th percentile) relative to the TSRs of the companies in the S&P 500 for the three-year performance period ranked at the 46th percentile of S&P 500 companies and resulted in a TSR modifier for the 2017-20192019-2021 performance period of +50-4.8 percentage points andfor a payout of 153.7%86.8% of performance units granted. A detailed depiction of thisour performance under these operating measures and the resulting calculation is on the next page.

 

 

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Compensation Discussion and Analysis

2019-2021 Performance Period Goal Design and Award Calculation

All operating measures and goals were established at the beginning of the three-year performance period and no alterations were made to respond to changing business conditions (i.e., the occurrence or challenges of the pandemic).

The Compensation Committee constructed the 2019-2021 performance period (January 1, 2019 to December 31, 2021) design with two non-GAAP operating measures of EPS growth and ROIC weighted equally in each year (one-half per measure). All operating measures and goals were established at the beginning of the 2019-2021 performance period. The Compensation Committee retained the same general performance award goal design as for the 2018-2020 performance period, including the requirement that the TSR modifier cannot exceed target (100%) regardless of our relative TSR performance if our absolute TSR over the performance period is less than zero.

2021 Operating Measures and Performance for the 2019-2021 Performance Period

  

Non-GAAP(1)

Operating

Measures

 

Minimum

(30%)

 

Low

(90%)

 

Target

(100%)

 

High

(110%)

 

Maximum

(170%)

 

2021 Actual

Performance


LOGO           

 

  EPS Growth  

($)

                 106.4%
  

$8.00

   

$11.00

   

$15.32

     

$19.00

    

$22.00

 
               

 

($17.69 actual)

 

        
 

 

ROIC

(%)

                 30.0%
  

27%

   

33%

   

41%

   

49%

    

55%

 
 

 

 (26.5% actual)

 

                  
      

 

  LOGO

 

 

68.2%

 

                

LOGO

(1)

The non-GAAP operating measures (EPS growth and ROIC) with respect to the 2019-2021 performance period are as reported and reconciled in Appendix B, except that operating measures for 2021 performance were further adjusted to include the impacts of gains on equity investments as prescribed by the 2019-2021 performance goals document. For this purpose, non-GAAP net income was increased by $338 million, or $0.59 per share and the tax rate used to calculate ROIC was adjusted accordingly to approximately 13.1%, resulting in a 0.1% reduction in ROIC.

(2)

Our targets for our 2019 and 2020 performance were disclosed under the 2019-2021 performance goals in our 2020 proxy statement filed with the Securities and Exchange Commission, or SEC, on April 7, 2020 and the 2021 Proxy Statement filed with the SEC on April 6, 2021, respectively.

(3)

TSR Measurement Points = average daily closing price of stock for the first 20 trading days beginning on the grant date and the last 20 trading days of the performance period.

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Compensation Discussion and Analysis

 

 

 

 

 

2017-2019 Performance Period Goal

Positive 2021 Say on Pay Vote Outcome and Compensation Design and Award Calculation

All operating measures and goals were established at theChanges in Response to 2021 Stockholder Input

beginning

In 2021, we received 93% stockholder support on our say on pay advisory vote. Our directors and management recognize the benefits from robust dialogue with our stockholders and we have engaged consistently in broad, direct, governance-focused stockholder outreach since 2011. Consistent with prior years’ practices, since our 2021 annual meeting of stockholders, we have engaged in governance-focused outreach activities and discussions with stockholders comprising approximately 52% of our outstanding shares. In addition to

these governance-focused outreach activities, we have more than doubled our participation in investor events and engagement sessions since 2017.

We will continue to solicit the three-year performance periodperspectives of our investors and share such perspectives with our Board. Among other topics, we invite dialogue with our stockholders regarding compensation best practices and policy issues to help inform our compensation program review process.

2019 Operating Measures

LOGO

Feedback From Our Stockholders and Performance                                                             Responsive Actions Taken by Our Board

In 2021, stockholders asked questions about our response to COVID-19 and ESG issues. The predominant feedback from investors with respect to our compensation and governance practices was that they are satisfied with our compensation program and governance practices.

Stockholder feedback is delivered to our Board. We will continue to engage with our stockholders to be sure we understand and address any concerns.

 

Non-GAAP(1)
Operating
Measures

Minimum

(50%)

Target

(100%)

Intermediate

(125%)

Maximum

(150%)

2019

Performance


LOGO           

  EPS Growth  

($)

136.8%

$14.75

£$11.60

$12.75

$14.35

³$15.20

Operating

Margin

(%)

75.3%

50.0%

£48%

52%

54%

³58%

ROIC (%)

66.6%

30.7%

£30%

32%

³36%

  LOGO

92.9%

2017-2019 Operating Measures Score

(Operating Measure Percentages 50 – 150% with linear
interpolation along the payout curve)

 

Operating Measure Percentages are Equally Weighted
for Each of the Three Years
Non-GAAP(1)
Operating
Measures
 2017(2) 2018(2) 2019 2017-2019
Average
Operating
Measures

EPS  

Growth ($)  

 

133.8%

($12.74)

 

142.9%

($14.37)

 

136.8%

($14.75)

 137.8%

Operating  

Margin (%)  

 

114.5%

(54.2%)

 

106.6%

(52.5%)

 

75.3%

(50.0%)

 98.8%

Operating   Expense  

Years 1 & 2  

(in billions)  

 

107.0%

($11.04)

 

50.0%

($11.91)

   74.5%

ROIC (%)  

Year 3  

   

66.6%

(30.7%)

 

 

118.4%

 

 

 

99.8%

 

 

 

92.9%

 

 

 

103.7%

 

 

2017-2019 S&P 500 Relative TSR(3) ModifierExamples of Actions Taken By the Board in Response to Stockholder Feedback

Expanded and enhanced a number of our disclosures, including:

Payout for Performance Relative to S&P 500 TSR Percentage

Amgen TSR³   75th percentile = 50% (Maximum)

Board gender and racial/ethnic diversity;
     Drug pricing practices; and
   Data from our annual Consolidated EEO-1 Report;(2)  

Actual Amgen

percentile

ranking 77.8th

percentile

resulting in a

+50% score

   Alignment of compensation program with strategic priorities.

Amgen TSR = 50   Mapping our ESG reporting to the SASBth(3) percentileLOGO= 0% (Target)

Amgen TSR£ 25th percentile =-50% (Minimum)

standards for our      industry;   

LOGO

If Amgen’s TSR is less than 0, the relative TSR modifier can be no greater than 0% (target).

 

LOGO

 

(1)

The operating measuresReference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of the 2017-2019 performance units were based onNon-GAAP financial results for 2017, 2018, and 2019 as reported and reconciled inAppendix B, except that operating measures were further adjusted for the impacts of Hurricane Maria as prescribed by the terms of the 2017-2019 performance goals document. For this purpose, operating expense was reduced by $147 million ($0.16 in EPS) for 2017 and increased by $21 million ($0.03 in EPS) for 2018, and increased by $49 million ($0.07 in EPS) for 2019.proxy statement.

(2)

Our targets forBeginning with our 2017 and 2018 performance were disclosed under the 2017-2019 performance goalsConsolidated EEO-1 Report filed in our 2018 and 2019 proxy statement, respectively, filed with the Securities and Exchange Commission on April 11, 2018 and April 8, 2019, respectively.2021.

(3)

TSR Measurement Points = Average daily closing price of stock for the first 20 trading days beginning on the grant date (May 1, 2017) and the last 20 trading days of the performance period (December 31, 2019).Sustainability Accounting Standards Board.

 

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Compensation Discussion and Analysis

 

 

 

 

 

Positive 2019 Say on Pay Vote Outcome and Engagement With Our Stockholders

In 2019, we received approximately 93% stockholder support on our say on pay advisory vote. We have engaged consistently in broad direct governance-focused stockholder outreach since 2011. Since our 2019 annual meeting of stockholders, in addition to outreach by our executives and Investor Relations department to our investors owning approximately 58% of our outstanding shares, we have engaged in governance-focused outreach activities and discussions with stockholders owning approximately 51% of our outstanding shares. These discussions have been valuable and informative and we will

continue to engage with our stockholders to further enhance our understanding of the perspectives of our investors.

In 2019, the predominant feedback from investors with respect to our compensation and governance practices was that they are satisfied with our compensation program and governance practices. We are pleased with our say on pay results and stockholder feedback, and will continue to engage with our stockholders to be sure we understand and address any concerns.

LOGO

Long-Term Incentive Equity Award Design in 20192021

 

 

In December 20182020 and March 2019,2021, the Compensation Committee reviewed, evaluated, and established a performance award goal design for the 2019-20212021-2023 performance period (January 1, 20192021 to December 31, 2021)2023) with input from management and FW Cook, to take into accountreflect stockholder discussions with our stockholders, and to continue to drive operating performance and financial discipline. For the 2019-20212021-2023 performance period, the Compensation Committee retained the same general performance award goal design as forthat of the 2018-20202020-2022 performance period includingwith the non-GAAP operating measures of EPS and ROIC weighted equally in each year measured against targets and goals pre-established at the beginning of the three-year performance period for each year of the performance period. The Compensation Committee selected non-GAAP

EPS to drive delivery of value to stockholders and ROIC to reflect our ongoing focus on remaining operationally disciplined in our management of our capital. The Compensation Committee also retained the TSR modifier of +/-30 percentage points and the requirement that the TSR modifier cannot exceed target (100%) regardless of our relative TSR performance if our absolute TSR over the performance period is less than zero. This feature providesrequirement ensures a greaterstronger tie to stockholders’ interests and investment

experience. The Compensation Committee moved to using two operating measures, retaining the twonon-GAAP operating measures of EPS growth and ROIC used for the last two years of the 2018-2020 performance period for the entire 2019-2021 performance period to continue to incentivize focus on delivering stockholder value and to emphasize our goal of remaining disciplined experience in our management of the business and use of capital, respectively. These operating measures are weighted equally(one-half per measure).a challenging market. A detailed depiction of the 2019-20212021-2023 performance period goal design can be found in “Performance Award Goal Design for the 2019-2021 Performance Period—“Elements of Compensation and Specific Compensation Decisions—2019-20212021-2023 Performance Period Goal Design and Award Calculation.

 

 

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Compensation Discussion and Analysis

 

 

 

 

 

Our 20192021 Compensation Program Highlights and Objectives

 

 

Total Target Direct Compensation Focuses on At Risk“At Risk” Compensation

(91%92% for our CEO and 82%84% for our other NEOs)

 

LOGO

LOGO

 

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Compensation Discussion and Analysis

 

 

 

 

 

How Compensation Decisions Are Made For Our Named Executive Officers

 

 

 

LOGOLOGO

  Roles and Responsibilities

 

 

Compensation Committee

ComposedBoard Committee composed solely of independent directors and reports to the Board

 

 

 

   Oversees the development and effective succession planning of our CEO and other members of Senior Management.

 

   Evaluates the performance of our CEO within the context of the financial and operational performance of the Company.

   Determines and approves compensation packages for our CEO, other NEOs, Executive Vice Presidents, Senior Vice Presidents, and Section 16 officers (collectively, “Senior Management”).

 

 

   Reviews and approves all compensation programs in which our NEOs participate.

   Oversees the development and effective succession planning of our CEO and other members of Senior Management annually.

   Exercises the sole authority to select, retain, replace, and/or obtain advice from compensation consultants, legal counsel, and other outside advisors and assesses the independence of each such advisor, taking into consideration the factors set forth in the Securities and Exchange Commission, or SEC, rules and The NASDAQ Stock Market listing standards.

 

   Oversees the Board’s relationship with, and response to, stockholders on executive compensation mattersmatters.

   Exercises the sole authority to select, retain, replace, and/or obtain advice from independent compensation consultants, legal counsel, and the Compensation Discussion and Analysis.other outside advisors.

 

 

 

Consultant to the Compensation Committee

Frederic W. Cook & Co., Inc., Independent consultant to, and retained directly by, the Compensation Committee

 

 

 

 

   Regularly attends Compensation Committee meetings, including meeting in executive session with the Compensation Committee.

   Provides advice and studies on the appropriateness and competitiveness ofof:

  our compensation program relative to market practice for our NEO compensation.

compensation;

   Provides advice and studies on  our equity programs.

programs; and

   Provides advice on  the selection of our peer group.

   Consults, advises, and makes recommendations, when requested, on executive compensation trends and developments.

   Consults and makes recommendations, when requested, ondevelopments, various compensation matters and compensation program designs and practices to support our business strategy and objectives.

 

 

   Coordinates and reviews the appropriateness of market data compiled by management.

   WorksAt the direction of the Compensation Committee, works with management to assess the potential risks arising from our compensation policies and practices.

 

 

 

CEO

Assisted by the Executive Vice President, Human Resources and other Company staff members

 

 

   Conducts performance reviews of the other NEOs and makes recommendations to the Compensation Committee with respect to compensation of other members of Senior Management other than himself.Management.

 

 

   Provides recommendations on the development of and succession planning for the members of Senior Management other than himself.Management.

Our Values

 

Annual performance reviews for each staff member (including NEOs) include an assessment of delivery of performance in alignment with our

The Amgen Values, a set of principles establishedformalized in 1996, that guide the wayhow we execute on our strategy, conduct business:our business, and what we reward.

 

  Amgen Values:      
  

   Be science-based;

  

   Trust and respect each other;

   
  

   Compete intensely and win;

  

   Ensure quality;

   
  

   Create value for patients, staff, and stockholders;

  

   Work in teams; and

   
  

   Be ethical;

  

   Collaborate, communicate, and be accountable.

   
   

Annual performance reviews for all staff members are designed to weight equally what was accomplished

as well as how it was accomplished in accordance with the Amgen Values

         

 

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Compensation Discussion and Analysis

 

 

 

 

 

Use of Independent Compensation Committee Consultant

To assist the Compensation Committee in its review and determination of executive compensation, the Compensation Committee retained and sought advice from FW Cook, an independent consultant. George B. Paulin, the Chairman of FW Cook, worked directly with the Compensation Committee in the roles and undertaking the responsibilities previously described in “How Compensation Decisions Are Made For Our Named Executive Officers” and specifically in 2019 provided consultation regarding regulatory updates, selection of our peer group, consultation on market competitiveness for our LTI equity award practices, competitive practice for CEO compensation, and general market practices for NEO compensation.

During 2019, the Compensation Committee, as in past years, had responsibility for engaging FW Cook and directed the nature of the activity and interchange of data between FW Cook and management. The Company did not engage FW Cook for any other services to the Company.

 

Retaining and Attracting Executive Talent

The Compensation Committee recognizes the unique demands of our industry, including its complex regulatory and reimbursement environment, and the challenges of running an enterprise focused on the discovery, development, manufacture, and commercialization of innovativebiologic medicines to address serious illness. The Compensation Committee believes that these unique demands require executive talent that has significant industry experience as well as, for certain key functions, specific scientific expertise to oversee research and development activities and the complex manufacturing requirements forof biologic products. Further, the Compensation Committee believes that these very particular skills and capabilities limit the pool of talent from which we can recruit and also cause our employees to be highly valued and sought after in our industry.

Use of Independent Compensation Committee Consultant

For 2021, to assist the Compensation Committee in its review and determination of executive compensation, the Compensation Committee retained and directed the nature of the activity between FW Cook, an independent consultant, and management. George B. Paulin, the Chairman of FW Cook, worked directly with the Compensation Committee until his retirement from FW Cook in May 2021, after which

Cimi Silverberg, Managing Director of FW Cook, worked directly with the Compensation Committee in the role of its independent consultant and undertaking the responsibilities previously described in “How Compensation Decisions Are Made For Our Named Executive Officers” and, in 2021, including providing advice and consultation regarding regulatory updates, selection of our peer group, and market competitiveness of our executive compensation programs. The Company did not engage FW Cook for any other services at the Company in 2021.

On an annual basis, FW Cook reviews our peer group with the Compensation Committee to determine whether the peer group remains appropriate. In 2019,July 2021, FW Cook recommended continuingthe continued use of the objective criteria previously established and makingto make no changes to the peer group.group and that the non-U.S. peer group companies be given a lower weighting than U.S. peer group companies to recognize that the non-U.S. peers reflect differences in law and governance practices. Based, in part, on these recommendations from FW Cook, as well as a review of the objective criteria, the Compensation Committee determined that the currentthis peer group, remainedcomposed of 14 companies (nine of which are based in the U.S.) remains appropriate.

 

 

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Compensation Discussion and Analysis

 

 

 

 

 

How We Establish Our Peer Group

 

   

20192021 Peer Group Companies

BiotechnologyWe focus on biotechnology and pharmaceutical companies with which we compete for executive talent.

   

Objective Criteria Considered

 

 

LOGO

2019

2021 Peer Group

(Companies in blue also list Amgen as a peer)  

 

  

   GICS codes of biotechnology (352010) and pharmaceuticals (352020);

 

   12-month average market capitalization between 0.25 and 4.0x that of Amgen’s average market capitalization for the same periodperiod;(1);

 

   Trailing four-quarter revenues between 0.25 and 4.0x that of Amgen’s revenuesrevenues;(1);

 

   Non-U.S. peers limited to those commonly identified as a “peer of peers”;

 

   Competitors for executive talent;

 

   Companies of comparable scope and complexity;

 

   Competitors for equity investor capital;

 

   Companies that identify us as their direct peer; and

 

   Companies with similar pay practices.

 

•   AbbVie Inc.

 

   Allergan plc

   AstraZeneca plc

 

•   Biogen Inc.

 

•   Bristol-Myers Squibb Company

 

•   Celgene Corporation

•   Eli Lilly and Company

 

•   Gilead Sciences, Inc.

•   GlaxoSmithKline plc

 

   Johnson & Johnson

 

•   Merck & Co., Inc.

 

•   Novartis AG

 

•   Pfizer Inc.

 

•   Regeneron Pharmaceuticals, Inc.

 

•   Roche Holding AG

 

   Sanofi S.A.

 

(1)

For purposes of the 20192021 peer group analyses:

 

    

Market Capitalization(a)

  

Revenues(b)

 

  Amgen

  

$122140 billion

  

 

$2425 billion

 

  Relative Peer Group Position

  

3rd Quartile (above median)2nd quartile

  

 

21ndst Quartilequartile

 

 

 (a)

Represents the12-month average market capitalization as of May 31, 2019.2021.

 
 (b)

Represents revenues for the trailing four quarters ended March 31, 2019.2021. Revenues for GlaxoSmithKline plc, Roche Holding AG, and Sanofi S.A. were converted into U.S. dollars using Standard & Poor’s Capital IQ.

 

 

Peer Group Data Sources

Our primary data sources for evaluating all elements of compensation for our CEO is data compiled by FW Cook from SEC filings of our peer group, including for the 25th, 50th, and 75th percentiles of the specific compensation elements paid to CEOs in our peer group. For our other NEOs, our primary data sources for evaluating all elements of compensation are the Willis Towers Watson Pharmaceutical Human Resources Association Executive Compensation Survey, or PHRAPHS Survey, which provides peer company data, augmented by the available data from proxy statements filed with the SEC for companies in our peer group. TheOur Executive Vice President, Global Commercial Operations role is well-matched in the PHRAPHS Survey. However, thethis role

is not consistently well-represented in the peer group proxy statements and, as a result, to reflect the scope and criticality of the role, is instead benchmarked to the second highest paid named executive officersofficer in such filings.

Further, as a result of our single business unit structure, our Executive Vice President, Operations role is not well-matched in either the PHS Survey or the peer group proxy statements as this role at our Company oversees a significantly broader scope of responsibilities. Due to this lack of comparability, the compensation for our Executive Vice President, Operations is compared to that of our other Executive Vice President roles that are generally similar in size and scope. Based on this data (to the extent applicable), the Compensation Committee is presented with a comparison of each NEO on a position or pay rank basis with an analysis of each element of direct compensation for such NEO at the 50th and 75th percentile of the peer group. Because PHRAPHS Survey and proxy statement data is only available for the previous calendar year, consistent with generally accepted practice, base pay data is aged forward to the current year based on expected salary movement. Annual cash incentive award and LTI equity award market data are not adjusted for aging.

 

The “Market Median” is determined for our CEO and our other NEOs based on the prior year’s compensation and is reviewed by the Compensation Committee to inform compensation decisions made in March of each year as follows:

Market Median

CEO(compiled by FW Cook)

Other NEOs

   50th percentile of each compensation element paid to CEOs in our peer group in the previous year from proxy statements.

   Average of the 50th percentile of each compensation element of our peer group from the PHRA Survey and proxy statements in the previous year (with base pay data aged forward to the current year) except for the Executive Vice President, Global Commercial Operations role as described above.

 

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Compensation Discussion and Analysis

 

 

 

 

 

The “Market Median,” as applicable, is determined for our CEO and our other NEOs based on the prior year’s compensation and is reviewed by the Compensation Committee to inform compensation decisions made in March of each year as follows:

Market Median

CEO (compiled by FW Cook)

Other NEOs

   50th percentile of each compensation element paid to CEOs in our peer group in the previous year as reported in applicable proxy statements.

   Average of the 50th percentile of each compensation element of our peer group from the PHS Survey and proxy statements for the previous year (with base pay data aged forward to the current year) modified for the Executive Vice President, Global Commercial Operations and Executive Vice President, Operations roles as described above.

Elements of Compensation and Specific Compensation Decisions

 

Described below are our three primary elements of executive compensation in order of magnitude: LTI equity awards; annual cash incentive awards; and base salaries.

 

Long-Term Incentive Equity Awards

Our compensation program aims to achieve the appropriate balance of compensation elements relative to the responsibilities of our staff members, with the result that the largest proportion of compensation for our CEO and the other NEOs is in the form of LTI equity awards that are risk-based and closely aligned with the creation of long-term stockholder value. For 2019,2021, equity-based compensation represents 78%79% of our CEO’s target compensation and 65%69% of target compensation for our other NEOs, and 50% of annual equity awards are in the form of long-term performance units. In addition, while being mindful of stockholder dilution (see below), we also grant LTI equity awards each year to nearly all of our staff members worldwide to increase staff awareness of how our performance impacts stockholder value. We believe that our practice of granting equity-based compensation broadly has been a significant factor in advancing our strategic priorities by aligning all of our staff members’ (including our NEOs’) interests with those of our stockholders, rewarding execution of our strategy, fostering long-term focus, and enhancing retention.

We Continue to Exercise Discipline in the Grant of Long-Term Incentive Equity Awards—Monitoring Dilution and Annual Equity Usage

Our Compensation Committee balances the use of equity to align staff members with our stockholders while striving to limit stockholder dilution to that amount which investors would expect to experience with members of our peer group. Annually, LTI equity award grant guidelines are established for each Company job level targeting the 50th percentile of our peer group for levels for which equity data is broadly available, setting an annual LTI equity award budget at approximately the 50th percentile of our peer group, and reviewing the Shareholder Value Transfer (SVT) associated with the proposed aggregate LTI equity award grants to ensure that our SVT is aligned with our peer group practices. (For certain lower job levels where data is not as comprehensive, we have developed guidelines that trendin-line with

available data and consider internal equity.) As illustrated, the resulting dilutive effect has been maintained at a generally trended downward.consistent level over the past seven years after being significantly reduced between 2012 and 2015.

LOGO

Amgen Ten Year Outstanding Potential Dilution (% Shares Outstanding)

LOGO

LOGO ï 2022 Proxy Statement57


Compensation Discussion and Analysis

Long-Term Incentive Equity Award Mix

As part of its annual evaluation of our LTI equity award practices, the Compensation Committee reviewed our LTI equity award mix with FW Cook and elected to maintain the previous year’s LTI equity award allocation for 20192021 given itspay-for-performance alignment. As such, 80% of our annual equity award value continued to be delivered as performance-based LTI equity awards consisting of performance units (50%) and stock options (30%). Time-vested RSUs, designed to foster retention, continued to comprise the remaining 20% of equity value. Both our stock options and RSUs generally vest over four years (with no vesting in the first year and vesting in three approximately equal annual installments on the second, third, and fourth anniversaries of the grant date). The delay in the commencement of vesting furthers the longer-term performance emphasis of our LTI equity award program and enhances retention.

LTI Equity Award Allocation

 

LOGO

LOGO

Performance Units 50% Stock Options 30% (earned at the end of a three-year performance period) RSUs 20%

 

 

LOGOï 2020 Proxy Statement    51


Compensation Discussion and Analysis

Value of 20192021 Annual Long-Term Incentive Equity Awards

Based on a review of Company and executive performance and market data, the Compensation Committee determined to grant the following annual LTI equity award grant values to our CEO and the other NEOs in March 2019,2021, with an effective grant date of May 3, 2019,April 30, 2021, the third business day after the announcement of our first quarter 20192021 earnings results. (For more information regarding the determination of the Market Median, see “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources” previously discussed.)results in accordance with our equity grant policy.

 

Named Executive Officer  

Performance

Units(1)

($)

   

Stock

Options

($)

   

Restricted

Stock

Units

($)

   

Total Equity

Value

Granted

($)

   

2018

Market

Median

($)

   

Difference vs. 

Market Median 

Over/ (Under) 

(%) 

   

Performance

Units(1)

($)

   

Stock

Options

($)

   

Restricted

Stock

Units

($)

   

Total Equity

Value

Granted

($)

   

2020

Market

Median(2)

($)

   

Difference vs. 

      Market Median 

Over/(Under) 

(%) 

 

Robert A. Bradway

   7,000,000    4,200,000    2,800,000    14,000,000    11,209,000    24.9     7,956,250    4,773,750    3,182,500    15,912,500    11,567,000    37.6  

Murdo Gordon

   2,000,000    1,200,000    800,000    4,000,000    3,918,612    2.1     2,500,000    1,500,000    1,000,000    5,000,000    3,781,204    32.2  

David W. Meline

   2,000,000    1,200,000    800,000    4,000,000    3,399,988    17.6  

David M. Reese

   2,000,000    1,200,000    800,000    4,000,000    4,010,465    (0.3)    2,400,000    1,440,000    960,000    4,800,000    3,978,254    20.7  

Jonathan P. Graham(2)

   

 

1,400,000

 

 

 

   

 

840,000

 

 

 

   

 

560,000

 

 

 

   

 

2,800,000

 

 

 

   

 

2,594,725

 

 

 

   

 

7.9 

 

 

 

Peter Griffith

   2,000,000    1,200,000    800,000    4,000,000    3,364,661    18.9  

Esteban Santos(3)

   2,375,000    1,425,000    950,000    4,750,000    n/a    n/a  

 

(1)

The 2019-20212021-2023 performance period runs from January 1, 20192021 through December 31, 2021.2023.

(2)

For more information regarding the determination of the Market Median, see “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources” previously discussed.

(3)

As previously discussed under “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources,” no comparable market data is available for Mr. GrahamSantos and his LTI equity award value was promotedestablished using comparisons to the values granted to our other Executive Vice President General Counsel and Secretary, effective October 22, 2019. Prior to that date, and at the time that the 2019 annual LTI equity awards were granted, Mr. Graham served as Senior Vice President, General Counsel and Secretary and the grant amounts reflect his role prior to his promotion, and does not give effect to his promotion grant.roles.

 

Based on the March 2019 Compensation CommitteeCommittee’s review of the market data in March 2021, the Compensation Committee approved an increase in Mr. Bradway’s LTI equity award value from $12.5$14.4 million to $14$15.9 million to reward Mr. Bradway for strong performance and excellentrecognize his successful leadership of the Company since 2012, noting that, since 2012 Mr. Bradway’s base salary and/or total target annual cash compensation had been belowduring the Market Median, and to differentiate his pay with equity that is substantially performance-based. In making its decision, the Compensation Committee noted that, while the Market Median for CEO pay had declinedpandemic, as a result of turnover in leadership at four of our peer group companies, among continuing incumbents at our peer group companies, the Market Median increased. The March 2019 Compensation Committee reviewwell as of the market data also resulted in granting Mr. Melineaccelerated Otezla integration, the same LTI equity award value ($4 million) that he had received in 2018 in recognitionsuccessful execution of Mr. Meline’s lengthy tenure in the role of Chief Financial Officer of large public companiesBeiGene, Ltd. collaboration, and the valueadvancement of his expertise.new approaches to the business’ activities that support the long-term growth of the Company. The Compensation Committee also granted Mr. Gordon and Dr. Reeseapproved increased LTI equity award grant values offor Mr. Gordon (from $4.1 million to $5 million), Dr. Reese (from $4.1 million to $4.8 million), and Mr. Santos (from $4 million each to position$4.75 million) to recognize their successful leadership of their respective total target direct compensation closerfunctions during the

pandemic, as well as of the strong execution of the accelerated integration of Otezla in 2020 following its acquisition in late 2019, the BeiGene collaboration established in 2020, and activities to enable the Company’s long-term growth. As 2020 was Mr. Griffith’s first year in the Chief Financial Officer role, while recognizing the breadth and importance of Mr. Griffith’s contributions to the Market Median for their respective roles. Further, in continued recognition ofCompany’s performance during a global pandemic, Mr. Graham’s tenure and diversity of experience in the

role of General Counsel at other complex publicly traded companies, the Compensation Committee granted Mr. Graham the sameGriffith’s LTI equity award value ($2.8 million) that he had received in 2018.was maintained at $4 million. The Compensation Committee concluded that the LTI equity award values granted to our NEOs were appropriate because they recognize and reward strong execution by our executives with compensation that is substantially “at risk,“at-risk, performance-based, and focused on the longer-term.

Promotion Equity Awards

Mr. Graham was promoted to Executive Vice President, General Counsel and Secretary effective October 22, 2019 to recognize the scope and impact of his service to the Company. In connection with Mr. Graham’s promotion, the Compensation Committee granted Mr. Graham a promotional RSU award on November 1, 2019 with a value of $2 million. This grant was intended to bring Mr. Graham’s 2019 annual LTI equity award grant morein-line with his role as Executive Vice President and will vest in accordance with our standard vesting schedule over four years, with no vesting in the first year and three approximately equal installments each year thereafter.longer term.

 

 

5258    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Compensation Discussion and Analysis

 

 

 

 

 

Performance Award Program 2017-20192019-2021 Performance Period Performance Units Earned

AtFor the endlast operating year of the 2017-2019our 2019-2021 performance period, our 2021 EPS performance for eachearned 106.4% of the three annualtarget and 2021 ROIC performance earned 30% of target, resulting in 2021 performance of 68.2% of target on these non-GAAP operating measures. Our performance with respect to our non-GAAP operating measures was averaged, resultingfor each year of the performance period resulted in 137.8%100.5% earned for EPS growth, 98.8%2019, 106% earned for operating margin,2020, and 74.5%68.2% earned for operating expense and ROIC over the three-year period.2021. These threenon-GAAPannual operating measure percentagespercentage calculations were then averaged for a total operating measures score of 103.7%91.6% for the three-year performance period. Based on our strong TSR ranking of 77.8the 46th percentile relative to the TSRs of the companies in the S&P 500, the total operating measures score of 103.7%91.6% was increaseddecreased by the maximum TSR adjustment of 504.8 percentage points, to 153.7%. This actual earnedresulting in a payout of 86.8% of target performance of 153.7% forunits granted. For the 2017-20192019-2021 performance period, this payout percentage resulted in the following number of shares of Common Stock being earned. Each earned performance unit converted to one share of Common Stock upon the payout date of March 20, 2020. See18, 2022. For additional information on the specific targets and actual performance and calculation of amounts earned, see the detailed description of the 2017-20192019-2021 performance period previously discussed.discussed on page 49.

 

Named Executive Officer  

Performance Units Value

Granted (Target)

($)

     

    Number of Performance

Units Granted

(#)

     

    Number of Shares of our

Common
Stock Earned
(1)

(#)

   

Performance Units Value

Granted (Target)

($)

   

  Number of Performance

Units Granted

(#)

   

  Number of Shares of our

Common
Stock Earned
(1)

(#)

 

Robert A. Bradway

   6,000,000      33,543      56,106    7,000,000    37,154    35,257 

Murdo Gordon(2)

   n/a      n/a      n/a    2,000,000    10,615    10,073 

David W. Meline

   1,750,000      9,783      16,363 

David M. Reese

   400,000      2,236      3,740    2,000,000    10,615    10,073 

Jonathan P. Graham

   

 

1,250,000

 

 

 

     

 

6,988

 

 

 

     

 

11,688 

 

 

 

Peter Griffith(2)

   n/a    n/a    n/a 

Esteban Santos

  

 

1,750,000

 

  

 

9,288

 

  

 

8,813

 

 

(1) 

Includes dividend equivalents earned on these amounts rounded down to the nearest whole number of shares (excluding fractional shares paid in cash).

(2)

Mr. GordonGriffith commenced employment with the Company in 2018 after the participants for the 2017-2019 performance period had been determined and did not receive any performance units for such performance period.late 2019. For a full description of thenew-hire LTI equity awards granted to Mr. GordonGriffith in connection with the commencement of his employment, see the subsection“Non-Direct Compensation and Payouts in Certain Circumstances—Change of Control Benefits and Offer Letter with Limited Severance Benefits—Offer Letter Letter—Mr. Gordon”Griffith” below.

 

LOGO  ï 20202022 Proxy Statement    5359


    

 

 

 

 

Compensation Discussion and Analysis

 

 

 

 

 

2018-2020

2020-2022 Performance Period Goal Design and Award Calculation

All operating measures and goals were established at the

beginning of the three-year performance period

Based on reviewperiod and deliberation in December 2017 and March 2018,no alterations were made to respond to changing business conditions (i.e., the occurrence

or challenges of the pandemic).

The Compensation Committee with input from management and FW Cook constructed the 2018-20202020-2022 performance period (January 1, 20182020 to December 31, 2020)2022) design to be similar to that ofretaining the 2017-2019same two operating measures as the 2019-2021 performance period design. All operating measures and goals were established at the beginning of the 2018-2020 performance period. For 2018, the three annualnon-GAAP operating measures established for 2018 under the 2017-2019 performance period were employed. For 2019 and 2020,non-GAAP EPS growth and ROIC two measures included among the three operating measures established for 2019 under the 2017-2019 performance period, are the operating measures under the 2018-2020 performance period.weighted equally in each year (one-half per measure) and relative TSR modifier (+/-30 percentage points). The TSR modifier was rebalanced forcannot exceed target (100%) regardless of our relative TSR performance if our absolute TSR over the 2018-2020 performance period from 50 to 30 percentage points to shift the weightingis less than zero. Our performance under these operating measures for 2021 yielded 113.2% of the TSR modifier to be in greater alignment with the value of each of the operating measures. For our 2019 operating performance measures (after weighting), we performed at 110.6%.target earned.

20192021 Operating Measures and Performance for the 2020-2022 Performance Period

 

  

    Non-GAAP(1)    

Operating

Measures

 

Minimum

(30%)

    

Low

(65%)

    

Target

(100%)

 

High

(135%)

 

Maximum

(170%)

 

2019

Performance

LOGO           

 

  EPS Growth  

($)

                

131.8%

($14.82)

  

£$9.05

   

$10.05

 

   

$12.55

     

$15.05

   

³$16.05

 
                              
 

 

ROIC

(%)

                

89.5%

(30.8%)

  

£26%

   

 

28%

 

     

32%

   

36%

   

³38%

 
                              
  

 

  LOGO

 

 

110.6%

 

                 
  Non-GAAP(1)
Operating
Measures
 

Minimum

(30%)

 

Low

(80%)

 

Target

(100%)

 

High

(120%)

 

Maximum

(170%)

 

2021

  Performance  


    LOGO      

 

  EPS Growth   

($) 

                 125.4%
  

$9.00

    

$11.00

   

$15.25

   

$17.50

     

$19.25

 
                     

 

($17.69 actual)

  
 

 

ROIC(2) 

(%) 

                 100.9%
  

15%

    

17%

   

22%

     

25%

   

27%

 
               

 

(22.1% actual)

        
      

 

  LOGO

 

 

113.2%

 

                

2018-2020 Operating Measures Score

(Operating Measure Percentages 30 – 170% with linear
interpolation along the payout curve)

Operating Measure Percentages are Equally Weighted

for Each of the Three Years

Non-GAAP(1)   
Operating  
Measures  
 2018(2) 2019 2020 2018-2020
Average
Operating
Measures

Operating  

Margin (%)  

Year 1  

 

105.4%

(52.6%)

     TBD

Operating Expense   Year 1  

(in billions)  

 

30.0%

($11.89)

 TBD

EPS  

Growth ($)  

Years 1, 2, and 3  

 

132.7%

($14.40)

 

131.8%

($14.82)

 

Pre-established

and to be

disclosed(3)

 TBD

ROIC (%)  

Years 2 and 3  

   

89.5%

(30.8%)

 TBD
 

 

89.4%

 

 

 

110.6%

 

 

 

TBD

 

 

 

TBD

 

2020-2022 Operating Measures Score

(Operating Measure Percentages 30 – 170% with linear
interpolation along the payout curve)

 

Operating Measure Percentages are Equally Weighted
for Each of the Three Years
Non-GAAP(1)(2)    
Operating
Measures
 2020(3) 2021 2022 2020-2022
Average
Operating
Measures

EPS

Growth ($)

 

155.7%

($16.60)

 

125.4%

($17.69)

 

 

Pre-established and to be disclosed(4)

 

 

TBD

ROIC(2)

(%)

 

85.8%

(20.4%)

 

100.9%

(22.1%)

 

 

TBD

 

 

120.8%

 

 

 

113.2%

 

 

 

TBD

 

 

 

TBD

 

 

2018-20202020-2022 S&P 500 Relative TSR(5)(4) Modifier

 

Payout for Performance Relative to S&P 500 TSR Percentage
 
 

Amgen TSR³75th percentile = 30% (Maximum)

 

 

Amgen TSR = 50th percentileLOGO = 0% (Target)

 

 

Amgen TSR£25th percentile = -30% (Minimum)

 

 

 

LOGO

If Amgen’s TSR is less than 0, the relative TSR modifier can be no greater than 0% (target).

 

LOGO

LOGO

Final 2018-20202020-2022 Performance Period Award Calculation 2018-20202020-2022 Non-GAAP(1) Average Operating Measures 2018 2019/2020 EPS Growth EPS Growth Operating Margin ROIC Operating Expense 2018-20202020-2022 Amgen Relative TSR Performance Final Payout Multiplier (0-200%) of target)

 

(1) 

The 2018non-GAAP operating measures (EPS growth, operating margin,2020 and operating expense) and the 20192021 non-GAAP operating measures (EPS growth and ROIC) with respect to the 2018-20202020-2022 performance period are as reported and reconciled inAppendix B., except that operating measures were further adjusted to include the impacts of gains on equity investments as prescribed by the 2020-2022 performance goals document. For this purpose, non-GAAP net income was increased by $338 million, or $0.59 per share and the tax rate used to calculate ROIC was adjusted accordingly to approximately 13.1%, resulting in a 0.1% reduction in ROIC.

(2) 

Our targetsFor the 2020-2022 performance period ROIC includes cash in invested capital to better align with our strategic priority of “Innovative Medicines” (which contemplates pursuit of innovation both internally and externally) by removing potential disincentives for our 2018 performance were disclosed under the 2018-2020 performance goals in our 2019 proxy statement filed with the Securitiesacquisitions that could yield innovative medicines and Exchange Commission on April 8, 2019.drive shareholder value.

(3)

Our targets for our 2020 Performance were disclosed under the 2020-2022 Performance Goals in our 2021 Proxy Statement filed with the SEC on April 6, 2021.

(4)

2022 targets arepre-established, but are not being disclosed at this time as they are competitively sensitive.

(4)(5) 

TSR Measurement Points = Averageaverage daily closing price of stock for the first 20 trading days beginning on the grant date and the last 20 trading days of the performance period.

 

5460    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Compensation Discussion and Analysis

 

 

 

 

 

2019-2021

2021-2023 Performance Period Goal Design and Award Calculation

All operating measures and goals were established at the

beginning of the three-year performance

period and no alterations were made to respond to changing business conditions (i.e., the challenges

of the pandemic).

The Compensation Committee constructed the 2019-20212021-2023 performance period (January 1, 20192021 to December 31, 2021)2023) design with the same twonon-GAAP operating measures as the 2019-2021 and 2020-2022 performance periods ofnon-GAAP EPS growth and ROIC weighted equally in each year(one-half per measure) and relative TSR modifier (+/-30 percentage points). SeeThe TSR modifier cannot exceed target (100%) regardless of our relative TSR performance if our absolute TSR over the detailed description of the 2019-2021 performance period previously discussed.is less than zero. Our performance under these operating measures for 2021 yielded 111.6% of target earned.

20192021 Operating Measures and Performance for the 2021-2023 Performance Period                                

 

  

    Non-GAAP(1)    

Operating

Measures

 

Minimum

(30%)

    

Low

(90%)

    

Target

(100%)

 

High

(110%)

 

Maximum

(170%)

 

2019

Performance

  LOGO   

 

  EPS Growth  

($)

                

108.8%

($14.82)

  

£$10.00

   

$12.00

 

   

$13.45

     

$15.00

   

³$17.00

 
                              
 

 

ROIC

(%)

                

92.2%

(30.8%)

  

£25%

   

29%

 

     

37%

   

45%

   

³49%

 
                              
  

 

  LOGO

 

 

100.5%

 

                 
  Non-GAAP(1)
Operating
Measures
 

Minimum

(30%)

 

Low

(80%)

 

Target

(100%)

 

High

(120%)

 

Maximum

(170%)

 

2021

  Performance  


    LOGO      

 

  EPS Growth  

($)

                 125.5%
  

$14.00

    

$16.00

   

$16.50

   

$17.00

     

$18.00

 
                     

 

($17.11 actual)

  
 

 

ROIC(2)

(%)

                 97.7%
  

18%

    

20%

     

22.5%

   

24%

   

26%

 
         

 

(22.2% actual)

              
  

 

  LOGO

 

 

111.6%

 

                

 

2019-2021 Operating Measures Score

(Operating Measure Percentages 30 – 170% with linear
interpolation along the payout curve)

 

 

Operating Measure Percentages are Equally Weighted

for Each of the Three Years

 

Non-GAAP(1)  
Operating  
Measures  

 

 

2019

 

 

2020

 

 

2021

 

 

 

2019-2021
Average
Operating
Measures

 

 

EPS  

Growth ($)  

 

 

108.8%

($14.82)

 

Pre-established

and to be

disclosed(2)

 TBD

ROIC(%)  

 

92.2%

(30.8%)

 TBD
 

 

100.5%

 

 

 

TBD

 

 

 

TBD

 

 

 

TBD

 

2021-2023 Operating Measures Score

(Operating Measure Percentages 30 – 170% with linear
interpolation along the payout curve)

 

Operating Measure Percentages are Equally Weighted
for Each of the Three Years
 Non-GAAP(1)(2) 
Operating
Measures
 2021 2022 2023 2021-2023
Average
Operating
Measures

EPS

Growth ($)

 

125.5%

($17.11)

 

Pre-established

and to be

disclosed(3)

 

 

TBD

ROIC(2)
(%)
 

97.7%

(22.2%)

 

 

TBD

 

 

111.6%

 

 

 

TBD

 

 

 

TBD

 

 

 

TBD

 

 

2019-20212021-2023 S&P 500 Relative TSR(4)(3) Modifier

 

Payout for Performance Relative to S&P 500 TSR Percentage

 
 

Amgen TSR³75th percentile = 30% (Maximum)

 

 

Amgen TSR = 50th percentileLOGO = 0% (Target)

 

 

Amgen TSR£25th percentile = -30% (Minimum)

 

 

 

LOGO

If Amgen’s TSR is less than 0, the relative TSR modifier can be no greater than 0% (target).

LOGO Final 2019-2021

LOGO

2021-2023 Performance Period Calculation 2019-20212021-2023 Non-GAAP(1) Average Operating Measures EPS Growth ROIC 2019-20212021-2023 Amgen Relative TSR Performance Final Payout Multiplier (0-200% of target)

 

 

(1) 

The 20192021 non-GAAP operating measures (EPS growth and ROIC) with respect to the 2019-20212021-2023 performance period are as reported and reconciled inAppendix B., except that operating measures were further adjusted to exclude the impact of direct on-going revenues and expenses from the acquisition of TeneoBio, Inc. as prescribed by the 2021-2023 performance goals document. For this purpose, non-GAAP net income was increased by $5 million, or $0.01 per share.

(2) 

2020For the 2021-2023 performance period ROIC includes cash in invested capital to better align with our strategic priority of “Innovative Medicines” (which contemplates pursuit of innovation both internally and 2021externally) by removing potential disincentives for acquisitions that could yield innovative medicines and drive shareholder value.

(3)

2022 and 2023 targets arepre-established, but are not being disclosed at this time as they are competitively sensitive.

(3)(4) 

TSR Measurement Points = Averageaverage daily closing price of stock for the first 20 trading days beginning on the grant date and the last 20 trading days of the performance period.

 

LOGO  ï 20202022 Proxy Statement    5561


    

 

 

 

 

Compensation Discussion and Analysis

 

 

 

 

 

Performance Award Goal Design for the 2020–20222022–2024 Performance Period

As part of its regular review and consideration of the performance award program, the Compensation Committee evaluated potential performance award goal designs for the 2020-20222022-2024 performance period (January 1, 20202022 to December 31, 2022)2024) with input from management and FW Cook at its December 20192021 and March 20202022 meetings. Based on such evaluations, the Compensation Committee retained the 2019-20212021-2023 performance period goalsgoal design as described previously for the 2020-2022 performance period. The operating measures ofnon-GAAP EPS and ROIC remain weighted equally in each year(one-half per measure) and are measured against targets and goalspre-established for each year of the2022-2024 performance period, at the beginning of the performance period. The Compensation Committee selectednon-GAAP EPS to measure delivery of value to stockholders, including among other things, the effectiveness of our execution of our strategic priority of “Capital Allocation and Investing for Long Term Growth” over an appropriate period. The Compensation Committee also retained the requirement that the TSR modifier could not effect a payout greater than target if our absolute TSR over the performance period was less than 0. The Compensation Committee revised the calculation ofnon-GAAP ROIC for the 2020-2022 performance period to include cash in invested capital.zero.

Dividend Equivalents

RSUs and performance units have dividend equivalent rights. Such dividend equivalents are payable only when, and to the extent that, the underlying RSUs and performance units are vested, earned, and converted to shares of Common Stock. The dividend equivalents may be paid in stock (with cash paid for fractional shares) or in cash at the Compensation Committee’s election. Stock options do not have dividend equivalent rights.

Plan Minimum Vesting Period of One Year; Actual Minimum ofGenerally Two Years

Mindful of stockholder concerns and best practices, our equity incentive plan requires that at least 95% of all equity awards, including RSUs, restricted stock, stock options, performance awards, and dividend equivalents granted to staff members (including NEOs) will be subject to a minimum vesting period of no less than one year. Our annual stock option and RSU grants generally vest over four years in

three approximately equal annual installments on the second, third, and fourth anniversaries of the grant date. This delayed vesting schedule further underscores the long-term focus of our LTI equity award program and enhances retention of staff members.

Long-Term Incentive Equity Awards Granted to Named Executive Officers in 20202022

In March 2020,2022, the Compensation Committee reviewed the LTI equity award grant values proposed to be granted to NEOs in 2020.2022. The Compensation Committee approved an increase in Mr. Bradway’s LTI equity award from $14 million to $14.4 millionvalue of the same value ($15.9 million) for Mr. Bradway in 2022 as it approved in 2021 to recognize his

sustained and continued successful execution against the Company’s strategic priorities, while navigating the ongoing challenges of the pandemic. The Compensation Committee also maintained Mr. Gordon’s LTI equity award grant ($5 million) to recognize Mr. Gordon’s successful leadership of his function during the Company through a periodpandemic and strong execution of transformationactivities necessary to meetenable the challengesCompany’s long-term growth. The Compensation Committee approved LTI equity grant values of the evolving biopharmaceutical marketplace.$4.5 million and $4.2 million for Dr. Reese and Mr. Santos, respectively, for 2022 to recognize their successful leadership of their respective functions. The Compensation Committee approved an increase in the LTI equity award from $4 million to $4.1 million for Dr. Reese to bring Dr. Reese’s total direct compensation closer to the Market Median and to reflect the importance of his contributions to the Company since his promotion to Executive Vice President. The Compensation Committee also approved an increase in the LTI equity award from $4 million to $4.1 million for Mr. Gordon to recognize his leadership of our Commercial team through a period of transition and his positioning of our Commercial team for a period of growth. The Compensation Committee granted Mr. Graham anincreased LTI equity award grant value of $3.9for Mr. Griffith (from $4 million to position his 2020 annual$4.5 million) in recognition of comparisons to peer group proxy reporting and to align Mr. Griffith closer to the LTI equity award grantin-line with his role asvalues of other Executive Vice President and to reflect the value to Amgen stockholders of the work in whichPresidents given his team is engaged. As Mr. Meline remains with the Company to assistcontinued successful performance in the transitionrole of our new Chief Financial Officer, he was granted an LTI equity award grant value equal to the same value as he received in 2019 ($4 million) which will bepro-rated according to the number of complete months of employment in 2020.Officer. The Compensation Committee concluded that the LTI equity award values granted were appropriate because they recognize and reward strong execution by our executives with compensation that is substantially “at risk,” performance-based, and focused on the longer-term.

Annual Cash Incentive Awards

Executive Incentive Plan

Annual cash incentive awards to our NEOs are generally made under our stockholder-approved Executive Incentive Plan, or EIP, which employs a formula that establishes a maximum award possible for each participant based on ournon-GAAP net income(1). For 2019, each of our NEOs was a participant in the EIP. This year, as in the past, actual awards under the EIP are determined by the Compensation Committee using its negative discretion under the EIP, with award determinations based on Company performance against the composite final score of thepre-established 2019 Company performance goals. In evaluating and confirming this approach, the Compensation Committee also considers the contributions of each participant’s role to our success during the year.

In March 2019, the Compensation Committee determined for the EIP participants, the definition ofnon-GAAP net income(1), the maximum award payable for each participant, the target annual cash incentive award opportunities. In addition, the Compensation Committee determined the plan design for the Global Management Incentive Plan, or GMIP, and Global Performance Incentive Plan, or GPIP, and the 2019 Company performance goals and weightings, and the percentages payable for threshold, target, and maximum performance.

Target Annual Cash Incentive Award Opportunity

After review of market data, the Compensation Committee determined that the target annual cash incentive award opportunities for our NEOs

 

 

(1)

Non-GAAP net income for purposes of the EIP is as reported and reconciled inAppendix B.

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Compensation Discussion and Analysis

 

 

 

 

 

would remain the same as 2018 (150% of base salary for Mr. Bradway and 100%Annual Cash Incentive Awards

Executive Incentive Plan

Annual cash incentive awards to our NEOs are generally made under our stockholder-approved Executive Incentive Plan, or EIP, which employs a formula that establishes a maximum award possible for each participant based on our non-GAAP net income.(1) For 2021, each of our NEOs was a participant in the EIP. This year, as in the past, actual awards under the EIP are determined by the Compensation Committee using its negative discretion under the EIP, with award determinations based on Company performance against the composite final score of the Executive Vice President NEOs).pre-established 2021 Company performance goals. In connection with Mr. Graham’s promotionevaluating and confirming this approach, the Compensation Committee also considers the contributions of each participant’s role to Executive Vice President, General Counselour success during the year.

In March 2021, the Compensation Committee determined for the EIP participants, the definition of non-GAAP net income(1), the maximum award payable for each participant, and Secretary effective October 22, 2019, Mr. Graham’sthe target annual cash incentive award opportunity was increased in alignment with other Executive Vice President NEOs to 100%,opportunities. In addition, the Compensation Committee determined the plan design for the Global Management Incentive Plan, or GMIP, and his 2019Global Performance Incentive Plan, or GPIP, and the 2021 Company performance goals and weightings, and the percentages payable for threshold, target, opportunity waspro-rated based on the number of days before and after the effective date of his promotion.maximum performance.

The maximum award under the EIP continued to be expressed as the EIPnon-GAAP net income(1) definition and, consistent with past years, was 0.125% for our CEO and 0.075% for each of the Executive Vice President NEOs, and 0.05% for Mr. Graham.other NEOs. As discussed previously, both historically and in 2019,2021, the Compensation Committee has paid well below the maximum award permitted under the EIP based on a practice of exercising negative discretion by using the Company performance goals composite final score under our GMIP

as applied to the participant’s target annual cash incentive award opportunity to determine actual awards.

2019Target Annual Cash Incentive Award Opportunity

After review of market data and consultation with FW Cook, the Compensation Committee determined that the target annual cash incentive award opportunities for our NEOs would remain the same as those of 2020 (150% of base salary for Mr. Bradway and 100% for each of the other NEOs).

2021 Company Performance Goals

While all of the goals measure single-year performance, taken as a whole, they are intended to positively position us for both near- and

long-term success, support our strategic priorities, and create stockholder value. The 20192021 Company performance goals approved by the Compensation Committee were based on our 20192021 budget and forecast at the time of such approval and are discussed on the following page.

For the 20192021 Company performance goals, in early March 2021, management recommended, and the Compensation Committee reviewed and concurred with, (i) an increase inreplacing the weighting for “Advance Early Pipeline” (from 5% to 10%)“Ensure Successful Integrations and Transactions” and “Fund Innovation Through Productivity” goals with the new annual priorities of “Environmental, Social, and Governance” and “Digital Transformation” to focus our entire Company on progressing programs in development, with a concurrent decreased weighting for “Execute Critical Launchesactivities to establish strong foundations to support achievement of our 2027 environmental sustainability targets and Long-Term Commercial Objectives” (from 10% to 5%);strengthen and (ii) replacing “Achieve Transformation Objectives” with “Achieve Productivity Objectives” to reflectimprove the Company’s movement beyond its 2014-2018 investor commitmentsdiversity, inclusion, and its focus on productivity to support continued reinvestmentbelonging efforts, and digital transformation activities that enable speed through the drug discovery, development, and market delivery process and, in opportunities (such as the early pipeline) while striving to maintain appropriate expense discipline. The goals also reflected the wide range of revenue uncertaintyturn, create value for 2019 given patent expiries, with targets consistent with the budgetour stockholders, staff members, and forecast at the time of such goal setting, and both the 2019 financial andnon-financial goals continuing to increase the level of execution necessary to deliver the required performance.society.

 

 

(1) 

Non-GAAP net income for purposes of the EIP is as reported and reconciled inAppendix B.

 

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20192021 Company Performance Goals and Results

The table below illustratessets forth the goals established, the weighting of each goal, and our actual performance for 2019.2021. Payouts can range from 0% to a maximum of 225% of target annual cash incentive award opportunity for each metric and the final company performance goals scoreCompany Performance Goals Score cannot exceed 225%. For additional discussion regarding our performance, please see “Aligning Pay With PerformancePerformance” and Execution of“Executing on Our Strategic Priorities.Priorities While Navigating the Impact of the COVID-19 Pandemic.

 

Deliver Results (60% weighting)

Deliver Results (60% weighting)

 

    

 

 

 

Weighted Score Achieved 103.7%  

 

 

Deliver Results (60% weighting)

 

  

 

Weighted Score Achieved 62.1%

($ In Millions)

Equally focused ontop- and bottom-line growth and assigned the largest percentage, consistent with the fundamental importance of financial performance to us and our stockholders in both the near- and long-term. No amounts can be earned for below-threshold performance for our financial metrics.

 

 

($ In Millions)

These goals are consistent with the fundamental importance of financial performance to us and our stockholders in both the near- and long-term, equally focused on top- and bottom-line growth, and assigned the largest percentage. No amounts can be earned for below-threshold performance for our financial metrics.

($ In Millions)

These goals are consistent with the fundamental importance of financial performance to us and our stockholders in both the near- and long-term, equally focused on top- and bottom-line growth, and assigned the largest percentage. No amounts can be earned for below-threshold performance for our financial metrics.

 

 

Goals

  

 

Weighting

 

    

 

Threshold

 

    

 

Target

 

    

 

Maximum

 

    

 

    Achieved  

 

  

 

Weighting

 

  

 

Threshold

 

  

 

Target

 

  

 

Maximum

 

  

 

Achieved

Revenues

  

 

 

 

30%

 

 

    

 

 

 

$20,453

 

 

    

 

$

 

22,100

 

 

    

 

 

 

$23,747

 

 

    

 

 

 

$23,362  

177.3%  

 

 

 

  

 

 

 

30%

 

 

  

 

 

 

$24,391

 

 

  

 

$

 

26,227

 

 

  

 

 

 

$28,062

 

 

  

 

 

 

$25,979

87.6%

 

 

 

Our rigorous revenue goal was established based on our guidance issued in early 2021 (between $25.8 and $26.6 billion) with our target goal exceeding our 2020 actual revenues. However, the cumulative decrease in patient visits and diagnoses over the course of the pandemic has suppressed the number of new patients starting treatment during 2020, affecting 2021 sales growth. Further, through 2021, while there has been gradual recovery in both patient visits and diagnoses, overall these have remained below pre-COVID levels. As a consequence, we did not achieve target performance for our revenue goal.

Our rigorous revenue goal was established based on our guidance issued in early 2021 (between $25.8 and $26.6 billion) with our target goal exceeding our 2020 actual revenues. However, the cumulative decrease in patient visits and diagnoses over the course of the pandemic has suppressed the number of new patients starting treatment during 2020, affecting 2021 sales growth. Further, through 2021, while there has been gradual recovery in both patient visits and diagnoses, overall these have remained below pre-COVID levels. As a consequence, we did not achieve target performance for our revenue goal.

 

 

Non-GAAP Net Income(1)

   30%      $7,084      $8,213      $9,342      

$9,028  

168.3%  

 

 

                       30%    $8,046    $9,515    $10,696    

$9,797

119.5%


 

Certain measurementsOur non-GAAP net income target was correlated to the midpoint of performance for thenon-financial metrics are subjective in natureour early 2021 non-GAAP EPS guidance and couldincluded increased research and development investment to support our longer-term performance. However, as a result in a very small payout percentage (less than 1% of, an annual cash incentive award).among other things, our disciplined operating expense management, we exceeded this target.

  Progress Innovative Pipeline (30% weighting)

  

Weighted Score Achieved 26.0%

 

Measures progress on both early- and later-stage product candidates to focus us on executing key clinical studies and delivering a robust product pipeline at all stages of the development continuum, which we believe is critical to our continued success over both the near- and long-term.

 

 

  Goals

  

Weighting

  

Results

  

            Achieved

 

 

Advance Early Pipeline

  

 

 

 

10%

 

 

 

 

  We generated a total of eight product teams (formed when a molecule has been judged to have the potential to be safe and effective in humans).

  

 

 

 

100.0%

 

 

   

  We initiated sevenfirst-in-human studies, including with product candidates for prostate and other solid tumor cancers, multiple myeloma, cardiovascular disease, and respiratory diseases.

  
   

  We advanced four programs through theearly-to-late stage portal (the period entering Phase 2 through Phase 3).

  

Execute Key Clinical Studies and Regulatory Filings

   20%  

  We achieved key clinical study milestones for Omecamtiv Mecarbil, KYPROLIS, Nplate, and ABP 798 (biosimilar rituximab (Rituxan®)).

   80.0% 
   

  We completed regulatory filings for EVENITY, Prolia, KYPROLIS, AVSOLA (biosimilar infliximab (Remicade®)), and ABP 215 (biosimilar bevacizumab).

 

  

  Deliver Annual Priorities (10% weighting)

  

Weighted Score Achieved 9.2%

 

  Goals

  

Weighting

  

Results

  

Achieved

 

 

Execute Critical Launches and Long-Term Commercial Objectives Focuses on executing on our key product launches.

  

 

 

 

5%

 

 

 

 

  We set aspirational internal goals to focus our entire Company on delivering on the promise of three important medicines – Repatha, Prolia, and Aimovig. While all three products delivered significant volume-driven growth, we did not meet our aspirational goals for Repatha and Aimovig.

  

 

 

 

77.2%

 

 

Achieve Productivity Objectives – Focuses on productivity to support continued reinvestment in opportunities (such as the early pipeline).

   5%  

  We established a target $280 million of gross operating expense savings. We realized approximately $286 million of gross savings that we reinvested in the business.

   106.8% 

 

  Progress Innovative Pipeline (30% weighting)

  

2019 Company Performance Goals FinalWeighted Score Achieved 53.6%  

 

Achieved 138.9%

Measures progress on both early- and later-stage programs and product candidates to focus us on executing key clinical studies and delivering a robust product pipeline at all stages of the development continuum, which we believe is critical to our continued success over both the near- and long-term.

Goals

 

Weighting

   

Results                                                                                                                                                                        

 

Achieved

 

Advance Early Pipeline—

Focused on incentivizing early-stage innovation discovery activities essential to our long-term success

  10%   

  We generated seven new product teams (formed when a molecule has been judged to have the potential to be safe and effective in humans), including for product candidates being studied in oncology, cardiovascular disease, and inflammation.

 

  We initiated four first-in-human studies, including for product candidates being studied in solid tumors (including non-small cell lung cancer, mesothelioma, pancreatic cancer, and ovarian cancer), neuroendocrine prostate cancer, nonalcoholic steatohepatitis (NASH), and multiple myeloma.

 

  Two molecules advanced through our early-to-late portal:

 

-  AMG 451 (a monoclonal antibody that inhibits OX-40 being developed in collaboration with Kyowa Kirin Co. Ltd.) is being investigated as a treatment for moderate-to-severe atopic dermatitis; and

 

-  Bemarituzumab (a monoclonal antibody that inhibits fibroblast growth factor receptor 2b from the Five Prime Therapeutics acquisition) is being investigated as a treatment for advanced gastric cancer. (Bemarituzumab is also being investigated as a treatment for gastroesophageal junction adenocarcinoma.)

 

  We committed to registrational studies for two programs:

 

-  LUMAKRAS is being explored in multiple Phase 1b combination cohorts for colorectal cancer and continues to progress. (LUMAKRAS is also being investigated for treatment as a monotherapy for colorectal cancer.); and

 

-  Tarlatamab (AMG 757) (a half-life extended anti-delta like ligand 3 x anti-CD3 bispecific T-cell engager molecule) is being investigated for the treatment of small-cell lung cancer. (Tarlatamab is also being investigated for the treatment of neuroendocrine prostate cancer.)

 

  200.0% 

Execute Key Clinical Studies and Regulatory Filings—

Designed to reward speed and effectiveness to maximize the value of our assets and deliver on our mission to serve patients

 

  20%   

  We executed on key clinical study milestones for LUMAKRAS (non-small cell lung cancer), Repatha (cardiovascular disease), acapatamab (prostate cancer), Olpasiran (cardiovascular disease), and ABP 654 (biosimilar ustekinumab (STELARA)).

 

  We completed key regulatory filings for LUMAKRAS (non-small cell lung cancer), TEZSPIRE (severe asthma with no phenotype or biomarker limitations), Otezla (approval of an expanded indication for plaque psoriasis in the U.S. and approval for mild-to-moderate psoriasis in China), and Aimovig (approval for migraine in Japan).

 

  167.9% 

 

(1)

Non-GAAP net income for purposes of the 20192021 Company performance goals of our annual cash incentive award programplan is reported and reconciled inAppendix B.

 

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Compensation Discussion and Analysis

 

 

 

 

 

Deliver Annual Priorities (10%  weighting)

Weighted Score Achieved 21.0%

Goals

 

Weighting

   

Results                                                                                                                                                                        

 

Achieved

 

Environmental, Social, and Governance—

Added to support activities to set us on a path to achieve our longer-term 2027 environmental sustainability targets and strengthen and embed more deeply the Company’s diversity, inclusion, and belonging efforts

 

  5%   

  To support our environmental sustainability 2027 targets, we established a Company-wide environmental goal to develop processes and capabilities at both the enterprise-wide level globally and across our Operations, Research and Development, and Global Commercial Operations functions, with the following requirements:

 

-  Annual auditable and verifiable conservation targets for the years 2021-2027;

 

-  Governance bodies and processes approved and established to oversee, develop, execute, and monitor the annual targets; and

 

-  Teams assembled and operating in accordance with charters approved by the governance bodies to further support activities necessary to achieve the conservation targets.

 

    One point was allocated for each of the three goal components (annual targets, governance bodies, and teams) by each of the four functional levels (enterprise-wide and across our Operations, Research and Development, and Global Commercial Functions) for a maximum of 12 points. Target completion was fourth quarter 2021, but accelerated attainment in the third quarter 2021 resulted in maximum achievement.

 

  To tangibly deepen and drive the Company’s diversity, inclusion, and belonging activities enterprise-wide and actively communicate our culture of belonging to all staff, we established an annual diversity, inclusion, and belonging goal for leaders at executive director and above levels to establish, document, and execute diversity, inclusion, and belonging action plans in 2021 with a target goal of 75% participation.

 

    We achieved our target with over 80% of our leaders at executive director levels and above establishing, documenting, and executing on their diversity, inclusion, and belonging action plans.

 

  195.8% 

Digital Transformation—

Created to encourage focus on activities that enable speed through the drug discovery, development, and market delivery process

 

  5%   

    To drive further efficiencies and speed throughout the drug discovery, development, manufacturing, and marketing efforts, we established a digital transformation goal to leverage digitization across our infrastructure and operations. For 2021, each function was challenged to establish digital value creation roadmaps to navigate and monitor the progress of its digital transformation journey to support greater efficiency and speed in its activities and operations.

 

    A target of at least six value creation roadmaps was set with eight or more roadmaps resulting in maximum achievement. Eight value creation roadmaps across our operations were established in 2021 with governance activities to simplify and automate our approach to our business as we work towards achieving maximum effectiveness and enable speed resulting in maximum achievement.

 

  225.0% 

Certain measurements of performance for the non-financial metrics are subjective in nature and could result in a very small payout percentage (less than 1% of an annual cash incentive award).

 

 

2021 Company Performance Goals Final Score

Achieved(1) 136.8%  

(1)

Percentages do not total to final score due to rounding.

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Compensation Discussion and Analysis

2021 Annual Cash Incentive Awards

As shown in the table above, our performance against the 20192021 Company performance goals yielded a composite final score of 138.9%136.8% and the Compensation Committee awarded actual annual cash incentive awards under the EIP to our NEOs based on this composite final score. No further discretion was employed.

 

Named Executive Officer  Target Opportunity
(% of Base Salary)
     Target 2019
Award($)
     Actual 2019  Award($)(1)   Target Opportunity
(% of Base Salary)
     Target 2021 Award($)     Actual 2021  Award($)(1) 

Robert A. Bradway

  

 

150

 

    

 

2,390,769

 

    

 

3,321,000

 

  

 

150

 

    

 

2,499,738

 

    

 

3,420,000

 

Murdo Gordon

  

 

100

 

    

 

1,021,154

 

    

 

1,418,000

 

  

 

100

 

    

 

1,067,742

 

    

 

1,461,000

 

David W. Meline

  

 

100

 

    

 

994,646

 

    

 

1,382,000

 

David M. Reese

  

 

100

 

    

 

970,139

 

    

 

1,348,000

 

  

 

100

 

    

 

1,059,039

 

    

 

1,449,000

 

Jonathan P. Graham

  

 

92

(2) 

    

 

878,494

 

    

 

1,220,000

 

Peter Griffith

  

 

100

 

    

 

1,010,373

 

    

 

1,382,000

 

Esteban Santos

  

 

100

 

    

 

989,750

 

    

 

1,354,000

 

 

(1)

Calculated in accordance with the 20192021 Company performance goals composite final score based on actual 20192021 earned base salary.

(2)

Mr. Graham’s target annual cash incentive award opportunity was increased from 90% to 100% of base salary in connection with his promotion to Executive Vice President, General Counsel and Secretary, effective as of October 22, 2019. The target opportunity is apro-rated bonus target based on the number of days at each target level before and after the effective date of his promotion.

 

20202022 Company Performance Goals

In March 2020,2022, the Compensation Committee established Company performance goals for 20202022 performance under our GMIP as follows:

 

 

 

20202022 Company Performance Goals

 

60% 

 

 

Deliver Results

 

 

    Revenues (30%)

 

    Non-GAAP Net Income (30%)

 

30% 

 

 

Progress Innovative Pipeline

 

   Advance Early Pipeline (10%)

 

    Execute Key Clinical Studies and Regulatory Filings (20%)

    Advance Early Pipeline (10%)

 

10% 

 

 

Deliver Annual Priorities

 

 

   Fund Innovation Through ProductivityEnvironmental, Social, and Governance (5%)

 

   Ensure Successful IntegrationsProcess Simplification and TransitionsAutomation (5%)

The Compensation Committee replaced “Execute Critical Launches and Long-Term Commercial Objectives” and “Achieve Productivity Objectives” with theadded a new annual prioritiespriority of “Fund Innovation Through Productivity”“Process Simplification and “Ensure Successful IntegrationsAutomation” as a goal that drives end-to-end simplification of our processes and Transitions” as goals that create productivitystrives to significantly increase the appropriate use of automation technologies across the Company and add an emphasis on integration-related priorities given the Company’s 2019 acquisitions and the BeiGene collaboration.to accelerate adoption of digital automation at all levels of our organization.

In March 2020,2022, the Compensation Committee reviewed the target incentive award opportunity for each NEO and determined that the existing target incentive award opportunity established for each NEO remains appropriate. No changes were made to the target incentive award opportunity for any NEO.

Base Salaries

Generally, in March of each year, the Compensation Committee reviews the peer group data compared with the available Market Median, considers our performance, market conditions, retention, and other such otherrelevant factors, deemed relevant, and receives management’s, including our CEO’s, assessment of the performance of each of the other NEOs, and recommendations regarding any base salary adjustments for them. The Compensation Committee uses our CEO’s evaluation of the performance of the NEOs (other than himself), the Compensation Committee’s own evaluation of our CEO’s performance, information with respect to each NEO’s experience and other qualifications, the Market Median for each available position and market conditions to determine each NEO’s base salary. No increase in base salary is automatic or guaranteed. For more information on how decisions are made,regarding the determination of Market Median, the peer group data reviewed, and the Executive Vice President, Operations role, see “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources” previously described.

In early March 2019,2021, the Compensation Committee reviewed the market competitiveness ofconsidered each NEO’s base salary employed atagainst the time based onavailable Market Median data, while taking into account the Company’s and such executive officer’seach NEO’s performance, experience and other qualifications, as well as the Company’s overall performance.current market conditions. In alignment with the base salary increases made to our staff members generally, the Compensation Committee increased Mr.Messrs. Bradway’s, Gordon’s, Griffith’s, and Santos’ base salaries by 2%. The Compensation Committee increased Dr. Reese’s base salary by 2.6%5.6% to bring it in-line with the Market Median for his position and eachto reflect the importance of his contributions to the other NEOs by 2.5%.Company in his role as Executive Vice President, Research and Development.

 

 

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Compensation Discussion and Analysis

 

 

 

 

 

20192021 Base Salary Market Position

The 20192021 base salaries as in effect at the end of 20192021 and the Market Median position as reviewed by the Compensation Committee in March 20192021 are shown in the table below:

 

Named Executive Officer  

        2018 Base Salary

($)

   

        Increase

(%)

   

        2019 Base Salary

($)

   

        2018 Market Median

($)

 

Difference vs.

        Market Median

Over/(Under)

(%)

   

2020 Base Salary

($)

   

Increase

(%)

   

2021 Base Salary

($)

   

2020 Market Median

($)

 

Difference vs.

Market Median

Over/(Under)

(%)

 

Robert A. Bradway

  

 

1,560,000

 

  

 

2.6

 

  

 

1,600,000

 

  

 

1,586,000

 

 

 

0.9

 

  

 

1,640,000

 

  

 

2.0

 

  

 

1,672,800

 

  

 

1,650,000

 

 

 

1.4

 

Murdo Gordon

  

 

1,000,000

 

  

 

2.5

 

  

 

1,025,000

 

  

 

1,033,452

 

 

 

(0.8

  

 

1,050,700

 

  

 

2.0

 

  

 

1,071,800

 

  

 

1,081,748

 

 

 

(0.9

David W. Meline

  

 

974,000

 

  

 

2.5

 

  

 

998,400

 

  

 

1,033,767

 

 

 

(3.4

David M. Reese

  

 

950,000

 

  

 

2.5

 

  

 

973,800

 

  

 

1,098,716

 

 

 

(11.4

  

 

1,013,000

 

  

 

5.6

 

  

 

1,070,000

 

  

 

1,060,140

 

 

 

0.9

 

Jonathan P. Graham

  

 

935,000

 

  

 

2.5

 

  

 

958,500

 

  

 

953,708

 

 

 

0.5

 

Peter Griffith

  

 

994,300

 

  

 

2.0

 

  

 

1,014,200

 

  

 

1,002,435

 

 

 

1.2

 

Esteban Santos(1)

  

 

974,000

 

  

 

2.0

 

  

 

993,500

 

  

 

n/a

 

 

 

n/a

 

(1)

As previously discussed under “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources,” no comparable market data is available for Mr. Santos.

 

20202022 Base Salary Adjustments

In March 2020,2022, the Compensation Committee reviewed the market competitiveness ofconsidered each NEO’s base salary based on a review of marketagainst the available Market Median data, while taking into account the Company’s and such executive officer’seach NEO’s performance, experience and other qualifications, as well as the Company’s overall performance.current market conditions. In alignment with the base salary increases made to staff members generally, the Compensation Committee increased Messrs. Bradway, Gordon, Meline,Bradway’s, Gordon’s, Griffith’s, and Graham’sSantos’ respective base salaries by 2.5%3.5%. The Compensation Committee increased Dr. Reese’s base salary by 4%9.8% to bring his base salary closer tomore in-line with the Market Median for his position.position and to reflect the importance of his contribution to the Company in his role as Executive Vice President, Research and Development.

Total Target Annual Cash Compensation

Total target annual cash is the sum of the NEO’s base salary and target annual cash incentive award.award, which is a multiple of base salary. The Compensation Committee believes that reviewing our NEOs’ total target

annual cash compensation, in addition to the available Market Median for each element of compensation, provides a useful check in making compensation decisions.

In March 2019,2021, the Compensation Committee reviewed total target annual cash compensation for each NEO compared to the available market data

and historical2020 total target annual cash compensation figures as depicted below. The Compensation Committee noted such total target annual cash compensation was generally below the Market Median with the exception of Messrs. Bradway and Graham. For Mr. Bradway, who was slightly above the Market Median,close to the Market Median for all peers declined as a result of turnover in leadership at four of our peer group companies where new incumbents were paid less than their predecessors, but among continuing incumbents, the Market Median increased. The Market Median for Mr. Graham’s position had declined in prior years causing Mr. Graham’s total target annual cash compensation to be above Market Median.available positions. The Compensation Committee took these metrics into accountfound such positioning and decidedsmall percentage over Market Median (less than 3%) to increase the value of LTI equity awards tobe appropriate for Mr. Bradway given Mr. Bradway’s sustained leadership in the CEO role and for 2019 to bringDr. Reese given the importance of his target total annual direct compensation (composed of base salary, target annual cash incentive award,contributions in his role as Executive Vice President, Research and target LTI equity award) closer to the Market Median of continuing incumbents, in lieu of increasing total target annual cash compensation, resulting in compensation that is more “at risk” and performance-based.Development. For more information regarding the determination of Market Median, and the peer group data reviewed, and the Executive Vice President, Operations role, see “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources” previously described.

 

 

Total Target Annual Cash Compensation

Total target annual cash compensation reviewed by the Compensation Committee in March 20192021 prior to the compensationbase salary changes being made are shown in the table below:

 

Named Executive Officer    

2019 Amgen Target

Total Annual Cash

($)

     

2018 Market Median

($)

     

Difference vs.

Market Median

Over/(Under)

(%)

     

2021 Amgen Target

Total Annual Cash

($)

     

2020 Market Median

($)

     

Difference vs.

Market Median

Over/(Under)

(%)

 

Robert A. Bradway

    

 

4,000,000

 

    

 

3,966,000

 

    

 

0.9

 

    

 

4,182,000

 

    

 

4,063,000

 

    

 

2.9

 

Murdo Gordon

    

 

2,050,000

 

    

 

2,083,471

 

    

 

(1.6

    

 

2,143,600

 

    

 

2,199,718

 

    

 

(2.6

David W. Meline

    

 

1,996,800

 

    

 

2,026,322

 

    

 

(1.5

David M. Reese

    

 

1,947,600

 

    

 

2,221,552

 

    

 

(12.3

    

 

2,140,000

 

    

 

2,093,906

 

    

 

2.2

 

Jonathan P. Graham

    

 

1,821,150

 

    

 

1,659,523

 

    

 

9.7

 

Peter Griffith

    

 

2,028,400

 

    

 

2,015,339

 

    

 

0.6

 

Esteban Santos(1)

    

 

1,987,000

 

    

 

n/a

 

    

 

n/a

 

(1)

As previously discussed under “How Compensation Decisions Are Made For Our Named Executive Officers—Peer Group Data Sources,” no comparable market data is available for Mr. Santos.

 

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Compensation Discussion and Analysis

 

 

 

 

 

Perquisites

Perquisites are limited in both type and monetary value. The Compensation Committee believes, however, that certain perquisites facilitate the efficient operation of our business, allowing our NEOs to better focus their time, attention, and capabilities on our Company, permit them to be accessible to the business as required, alleviate safety and security concerns, and assist us in recruiting and retaining key executives. The perquisites provided to our NEOs generally include an allowance for personal financial planning services, including tax preparation services (not to exceed $15,000 annually in aggregate), annual physical examinations, Company-paid moving and relocation expenses paid on behalf of newly hired and current executives who agree to relocate to work on the Company’s behalf and, in limited instances, personal expenses when on business travel such as guests accompanying NEOs. Certain of our NEOs also have access to a Company car and driver and, subject to the approval of our CEO, the Company aircraft for personal use. Our CEO is encouraged to use our Company aircraft for all of his travel (business and personal) because the Compensation Committee believes that the value to us of making the aircraft available to our CEO, in terms of safety, security, accessibility, and efficiency, is greater than the incremental cost that we incur. No taxgross-up reimbursements are provided to NEOs, except in connection with reimbursement of moving and relocation expenses consistent with our other staff members and our general relocation policy.

We believe that providing taxgross-up reimbursements on the applicable moving and relocation expenses paid on behalf of newly hired and current executives who agree to relocate on the Company’s behalf is appropriate because it treats these executives in a similar manner asnon-executives under our Company-wide policy which is designed to incentivize optimal deployment of our human resources in support of the Company’s strategy. It also assists in the attraction and retention of the executive talent necessary to compete successfully.

We provide limited home sale loss assistance for Senior Vice Presidents and above in connection with relocations that benefit us and are at our request, and in certain new hire situations. We do not provide taxgross-ups for assistance with loss on sale of a home. Our limited home sale loss assistance serves as an important tool in inducing senior management to fully commit to their new role and relocation.

Our Company-wide policy includes a repayment provision applicable to all staff members (including our NEOs) that requires a new staff member hired from outside the Company or staff members who accept an assignment and relocate, to repay us for moving and relocation expenses and home loss assistance incurred by us in the event that the staff member does not complete the move, resigns, or is discharged for cause within two years of the employment start date or relocation date, as applicable (with apro-rata refundrepayment in the second year).

 

 

Compensation Policies and Practices

 

Recoupment

 

Clawback Policy. We have a clawback policy that requires our Board to consider recapturing past cash or equity compensation payouts awarded to our executive officers, including our NEOs, if it is subsequently determined that the amounts of such compensation were based on financial results that are later restated and the executive officer’s misconduct caused or partially caused such restatement.

Equity Recoupment ProvisionsPolicy. In the course of our engagement activities, we explored with certain stockholders additional recoupment mechanisms. In December 2020, after discussions of recoupment mechanisms, the Compensation Committee adopted an executive officer equity recoupment policy that provides the Compensation Committee with the ability to cause the forfeiture and cancellation of unvested equity awards and any unexercised portion of stock options (granted after December 31, 2020) in the event an executive officer is terminated for engaging in misconduct that caused serious financial or reputational damage to the Company (including, but not limited to, a financial restatement). If an executive officer is subject to an investigation potentially implicating conduct that could result, or may have resulted, in serious financial or reputational damage to the Company, the Company may freeze access to any unvested equity awards regardless of grant date and any vested but unexercised stock options granted after December 31, 2020, during the investigation, and such unvested equity awards and unexercised stock options may ultimately be subject to forfeiture and cancellation.

Cash Incentive Award Recoupment. Our cash incentive award programs (EIP, GMIP, and GPIP) expressly allow the Compensation Committee, or management, as appropriate, to consider employee misconduct that caused serious financial or reputational damage to the Company when determining whether an employee has earned an annual cash incentive award or the amount of any such award. This provision is

These provisions and policies do not intended to limit any other action that the Company could take against an employee, including other disciplinary actions (up to(including termination), ordinary course performance considerations, disclosure of wrongdoing to the government, and pursuit of any other legal claims against such employees.

Clawback Policy

We have a clawback policy that requires our Board to consider recapturing past cash or equity compensation payouts awarded to our executive officers, including our NEOs, if it is subsequently determined

that the amounts of such compensation were determined based on financial results that are later restated and the executive officer’s misconduct caused or partially caused such restatement.

Stock Ownership and Retention Guidelines

Our stock ownership guidelines require our executives to hold a meaningful amount of our Common Stock, promote a long-term perspective in managing the Company, further aligning the interests of our executives and stockholders and mitigating potential compensation-related risk. Our guidelines require that each officer who has not met their ownership requirements must retain shares of our Common Stock acquired through the vesting of RSUs, the payout of performance units, and the exercise of stock options awarded net(net of shares retained by us to satisfy associated tax withholding requirements and exercise price amounts,amounts) until such officer has reached his or her required stock ownership level.

 

 

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Compensation Discussion and Analysis

 

 

 

 

 

Stock Ownership Guidelines Requirements

The stock ownership guidelines for 2019 were:2021 are set forth in the table below. All executives currently employed by the Company and subject to stock ownership requirements were in compliance with their respective stock ownership requirement in 2021.

 

Position

  

Stock Ownership Requirement

    

Compliance  

Chief Executive Officer(1)

  

6x base salary

    

✓  

Executive Vice President

  

3x base salary

    

✓  

Senior Vice President

  

2x base salary

    

✓  

Vice President

  

1x base salary

    

✓  

 

(1)

Mr. Bradway exceeded his ownership requirement and holds approximately 53more than 74 times his base salary, or 9more than 12 times his stock ownership requirement as of October 18, 2019, the effective date of certifications.December 31, 2021.

 

The following holdings count towards satisfying these stock ownership requirements:

 

sharesShares of our Common Stock beneficially held that are not subject to forfeiture restrictions;

 

sharesShares of our Common Stock held through a 401(k) plan or other qualified pension or profit-sharing plan; and

 

sharesShares purchasable with funds then allocated under our Employee Stock Purchase Plan.

Executives are generally given five years following their placement into a given job level to comply with these guidelines. Executives who are promoted to a status with a stock ownership level higher than the executive was previously required to satisfy, have three years to comply with the new ownership level if the executive has been subject to the stock ownership guidelines for five or more years. Once these ownership guidelines are met, executives are required to maintain such ownership until they change job levels or are no longer employed by us. As of October 18, 2019,15, 2021, the effective date of our executive certifications, all executive officers, including our NEOs who were expected to meet such guidelines, were in compliance. Mr. Gordon commenced employment with our Company on September 3, 2018 and has until 2023 to meet his guidelines. Dr. ReeseMr. Griffith commenced employment with our Company on October 23, 2019 and Mr. Graham were promoted from Senior Vice Presidenthas until 2024 to Executive Vice President roles on July 26, 2018 and October 22, 2019, respectively, and, as a result, now have until 2021 and 2023 to comply with the new ownership level associated with the Executive Vice President role.meet his guidelines.

Insider Trading Policy and Practices

All staff members and our Board are prohibited from: (i) buying or selling our Common Stock while aware of any material nonpublic information; (ii) engaging in short sales with respect to our Common Stock; (iii) pledging or purchasing our Common Stock on margin;margin(1); or (iv) entering into any derivative, hedging, or similar transactions with respect to our Common Stock, including any transactions that hedges or offsets, or is designed to hedge or offset, any decrease in the market value of Amgen stock. Examples of prohibited derivative transactions include, but are not limited to, purchases or sales of puts and calls (whether written or purchased or sold), options (whether “covered” or not), forward contracts, including but not limited to prepaid variable forward contracts; put and call “collars” (“European” or “American”),

“equity” “equity” or “performance” swap or exchange agreements or any

similar agreements or arrangements, however denominated, in our securities.

Policies for Grants of Long-Term Incentive Equity Awards

In accordance with our equity awards policy, our regular annual LTI equity award grants are typically approved by the Compensation Committee (for grants of equity awards to Senior Management, including our NEOs) or the Equity Award Committee (for grants to all other staff members) in advance with a grant date that is the third business day after the release of our next quarterly or annual earnings announcement after the date of determination by our Compensation Committee or Equity Award Committee, as applicable. Our NEOs may also receive special equity awards as determined by the Compensation Committee as new hires or for recognition and retention, promotions, or other purposes, but the effective date of such grants is generally also only on the third business day after the release of our quarterly or annual earnings after the date of determination by our Compensation Committee and the relevant new hire, promotion, or other date.Committee.

Tally Sheets

The Compensation Committee annually reviews tally sheets for each NEO, setting forth all components of compensation, including compensation payable at termination, retirement, or a change of control. These tally sheets summarize the number of shares and the value at a given price of the LTI equity awards held by each NEO, as well as each NEO’s individual cumulative account balances in our benefit plans. These tools are employed by the Compensation Committee as a useful check on total annual compensation and the cumulative impact of our long-term programs and are considered important to understand both the overall and longer-term impact of compensation decisions.

The Compensation Committee may increase or decrease certain individual elements of compensation to align total compensation with peer group market data and to promote internal equity among our NEOs, other than our CEO, and use the information provided by these tally sheets to make such determination. No material adjustments to total compensation for any of our NEOs were made as a result of the review of these tally sheets by the Compensation Committee in 2019.2021.

 

 

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

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Compensation Discussion and Analysis

 

 

 

 

 

Stockholder Outreach—Executive Compensation Website

We maintain a website accessible throughout the year atwww.amgen.com/executivecompensation(1), which provides a link to our most recent proxy statement and invites our stockholders to fill out a survey to provide input and feedback to the Compensation Committee regarding our executive compensation policies and practices. All input from our stockholders is valuable and the Compensation Committee reviews your input and appreciates your time and effort in completing the survey.

Approach to Pricing Our Products

We take a thoughtful approachare committed to pricing our products according to the value they deliver and employ flexible pricing approaches to help promote patient access. We have internal processes and controls in place to help ensure that pricing decisions are thoroughly and appropriately vetted prior to implementation with involvement from senior management. This process includes routine presentations to our Corporate Responsibility and Compliance Committee

and our Board on

drug pricing practices. Our strategy includes a focus on innovative drugs and biosimilars that can deliver volume-driven growth, not simply price. And, in 2019,unit growth. In 2021, the average net price for Amgen medicines declined for a fourth straight year while our revenues benefited from volume-drivenvolume-based growth from a number ofacross our newer innovative medicines that grew units double digit or better, including Repatha, Parsabiv, BLINCYTO, Aimovig, and Prolia, rather than price increases.portfolio. We have and continue to disclose in our annual report on Form 10-K and our quarterly reports on Form 10-Q, the pricing trends impactingsignificant to our business, including, for 2019, that we continued to expect a lower net selling price in the aggregate compared with that of 2018.business. We believe that we have the appropriate governance mechanisms, oversight and processes in place to ensure that pricing decisions are made in-line with our values and our mission to serve patients. In addition, our Compensation Committee annually completes a thoughtful and rigorous evaluation of our executive compensation program for alignment with our mission to serve patients and deliver stockholder value without encouraging excessive or inappropriate risk-taking by our executives. A full description of risk management by our Compensation Committee and our ESG efforts can be found in the “Corporate Governance” section, including the subsections “—Compensation Committee Risk Management” and “—Our Approach to Environmental Sustainability, Social Responsibility, and Human Capital Management.”

 

 

Non-Direct Compensation and Payouts in Certain Circumstances

 

 

Change of Control Benefits and Offer Letter With Limited Severance Benefits

Our CEO and other NEOs are participants in our double-trigger Change of Control Severance Plan discussed below. In connection with new hires, we typically enter into offer letters detailing their initial compensation and requirements to pay back certain elements of compensation. To attract talented executives from outside the Company, our offer letters generally include severance terms that apply to terminations initiated by us and occur for reasons other than for “cause” within three years from the date of hire. These benefits are generally provided to officer-level candidates to provide an incentive for them to join us by reducing the risks associated with making such a job change. Other than the foregoing, our CEO and NEOs are not covered by contractual arrangements that provide for severance or other benefits in the event of termination.

Offer Letter—Mr. Gordon

Mr. Gordon, who commenced employment as our Executive Vice President, Global Commercial Operations, effectiveon September 3, 2018, was subject to an offer letter that was negotiated in connection with his hiring and was approved by the Compensation Committee. The terms of Mr. Gordon’s limited severance benefits expired on September 3, 2021. Mr. Gordon’s new hire inducement RSUs valued at $6.4 million and the $1 million contribution to his Deferred Compensation Plan account became fully vested as of September 3, 2021.

Offer Letter—Mr. Griffith

Mr. Griffith, who commenced employment as our Executive Vice President, Finance, on October 23, 2019, and became our Executive Vice President and Chief Financial Officer on January 1, 2020, is currently subject to an offer letter that was negotiated in connection with his hiring. The terms of the offer letter were approved by the Compensation Committee. We agreed to provide Mr. Gordon’s offer letter included our standard relocation assistance to facilitate Mr. Gordon’s relocation from New Jersey to California.Griffith with a base salary of $970,000, and, consistent with each of the other Executive Vice Presidents, a target annual cash incentive award opportunity of 100% of base salary, both of which were targeted at the Market Median.(2) We also agreed to provide Mr. GordonGriffith with RSUs valued at $6.4 million. To aligna $500,000 sign-on bonus to induce Mr. Griffith to accept our offer, however, such sign-on bonus was subject to recoupment if, within 24 months from his hire date, Mr. Griffith resigned his employment with the value being replaced, this grant vests over three years beginning on the first anniversary of the grant date through the third anniversary at a rate of 35%, 35%, and 30% each year, respectively, contingent upon Mr. Gordon being actively employed withCompany or for any reason his employment was terminated by us through each vesting date. To further induce

Mr. Gordon to join our Company, wefor “cause.” We also agreed to provide Mr. GordonGriffith with performance unitsRSUs valued at $3.5$4 million which will vest aton the endsecond, third, and fourth anniversaries of the performance period (November 2, 2018 to December 31, 2020) contingent upon Mr. Gordon being actively employed through the vesting date. The Compensation Committee concluded that these LTI equity award values were appropriate because they provide compensation that is focused on the longer-term to compensate Mr. Gordon for equity forfeited as a result of his leaving his previous employer, to induce him to join the Company, and to provide long-term incentives that tie a significant portion of Mr. Gordon’s compensation to the value of our stock in alignment with our stockholders’ interests. To compensate for Mr. Gordon’s forfeiture of certain pension benefits at his previous employer, Mr. Gordon was also provided with a contribution to his Deferred Compensation Plan of $1 million which vestsgrant date at a rate of 33%, 33%, and 34% each year, through the third anniversary of his date of employmentrespectively, contingent upon Mr. Griffith being actively employed with us as long asthrough each vesting date. The Compensation Committee concluded that this LTI equity award value was appropriate because it provides compensation that is focused on the longer-term and targeted at the Market Median. Mr. Gordon remains actively and continuously employed by us. We also agreed to reimburse Mr. Gordon for any claim resulting from Mr. Gordon’s employment with us due to any recoupment from Mr. Gordon by his previous employer for previously earned compensation (up to $2 million). Mr. Gordon’sGriffith’s offer letter also provides for cash severance protection for three years following his employment date equal to two year’s annual base salary and target annual cash incentive award, plus up to 18 months of COBRA(1) medical and dental coverage paid for by us. As discussed above, benefits of this type are often provided to officer-level candidates to provide an incentive to them to join our Company by reducing the risk of making such a job change. These severance benefits expire on September 3, 2021, and are payable only if Mr. Gordon is terminated other than for “cause.”

 

 

(1) 

The Consolidated Omnibus Budget Reconciliation ActReference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of 1985.this proxy statement.

(2)

Measured using information available at the time the Compensation Committee reviewed and approved Mr. Griffith’s compensation.

 

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Compensation Discussion and Analysis

 

 

 

 

 

paid for by us. As discussed above, benefits of this type are often provided to officer-level candidates to provide an incentive to them to join our Company by reducing the risk of making such a job change. These severance benefits expire on October 23, 2022, and are payable only if Mr. Griffith is terminated other than for “cause.”

Change of Control and Severance Benefits

Double Trigger Change of Control Severance Plan

In the event of a change of control and a qualifying termination, our Change of Control Severance Plan provides severance payments to 1,6611,716 U.S. staff members (as of December 31, 2019)2021), including each NEO. There are no taxgross-up payments provided under the plan. The plan is structured so that payments and benefits are provided only if there is both a change of control and a termination of employment, either by us other than for “cause” or “disability” or by the participant for “good reason” (as each is defined in the plan)—sometimes referred to as a “double-trigger”—because the intent of the plan is to provide appropriate severance benefits in the event of a termination following a change of control, rather than to provide a change of control bonus. The cash severance multiple for our CEO and all other NEOs is two times annual cash compensation. The payments and benefit levels under the Change of Control Severance Plan do not influence and were not influenced by other elements of compensation. The Change of Control Severance Plan was adopted, and is continued by the Compensation Committee:

 

To reinforce and encourage the continued attention and dedication of members of management to their assigned duties without the distraction arising from the possibility of a change of control;

 

To enable and encourage management to focus their attention on obtaining the best possible deal for our stockholders and making an independent evaluation of all possible transactions, without being influenced by their personal concerns regarding the possible impact of various transactions on the security of their jobs and benefits; and

 

To provide severance benefits to any participant who incurs a termination of employment under the circumstances described within a certain period following a change of control in recognition of their contributions to the Company.

Change of Control and Severance Treatment of Long-Term Incentive Equity Awards

Restricted Stock Units and Stock Options

All unvested RSUs and stock options have “double-trigger” acceleration of vesting that requires a qualifying termination in connection with a change of control. All RSUs and stock options vest in full only if the grantee’s employment is involuntarily terminated other(other than for “cause” or “disability,”“disability”), or in the case offor staff members subject to the Change of Control Severance Plan, is voluntarily terminated with “good reason,” in each case within two years following a change of control. All RSUs and stock options also vest in the event of a termination of employment due

to death or “disability” as follows: full vesting for grants made before the year of death or disability; and pro-rata vesting (based on months worked) for grants made during the year of death or disability. In the event of “retirement,” RSUs and stock options granted before the year of retirement continue vesting on their original vesting schedule, and for those awards granted in the year of retirement, they vest pro-rata based on months worked.

Performance Units

The Compensation Committee has maintained change of control features for each of the performance periods under our performance award programs to ensure that these programs reward participants for our performance until the successful closing of any change of control. In general, the performance units are earned based on a truncated

performance period and our performance throughending on the quarter end immediately prior to any change of control (or target performance for the operating measures if the change of control occurs in the first year of a performance period). If the change of control occurs within the first six months of a performance period, the amount earned ispro-rated based on the number of months of the performance period prior to the change of control. In the event of a termination of employment due to death, disability, or retirement, our performance units provide for potentialearn-out at the end of the performance period based on actual results with the amount earnedpro-rated based on the termination date. For additional information on the levels of payout, see “Potential Payments Upon Termination or Change of Control—Long-Term Incentive Equity Awards—Performance Units” in our Executive Compensation Tables.

Limited Retirement Benefits and Deferred Compensation Plan

Health, retirement, and other benefits programs are generally available to our U.S.-based staff members, including our NEOs, and arewith the overall benefit programs typically targeted to align in value with those programs offered by our peer group. The primary survey used to make this comparison is the Aon Hewitt Benefit Index®, last updated as of May 2018July 2020, using a comparator group of 14 companies chosen by Amgen as representative of its peer group. The data generated from this survey is used by the Compensation Committee and management in evaluating the competitive positioning and program design of these health, retirement, and other benefit programs.

Retirement and Savings Plan, Supplemental Retirement Plan, and Nonqualified Deferred Compensation Plan

Our Retirement and Savings Plan, or 401(k) Plan, is available to U.S.-based staff members of the Company and participating subsidiaries.subsidiaries (except Puerto Rico). All 401(k) Plan participants are eligible to receive the same proportionate level of matching and core contributions from us.

We credit to our Supplementalprovide a 5% contribution on eligible compensation and 5% matching contribution on voluntary deferrals under the 401(k) Plan for each staff member. The Retirement and Savings Plan or SRP, whichfor Amgen Manufacturing Limited is available to all 401(k) Plan participants, Company core and matching contributions on eligible compensation that cannot be made to the 401(k) Plan because they relate to compensation that is in excess of the maximum amount of recognizable compensation allowed under the Internal Revenue Code’s qualified plan rules. We also credit staff members in the SRP for lost 401(k) Plan Company match and core contributions resulting from making a deferral into the Nonqualified Deferred Compensation Plan, or NDCP. Earnings under the SRP are market-based—there are no “above market” or guaranteed rates of returns offered in this plan and this plan enables us to provide the same percentage of base salary and annual cash incentive award as a retirement contribution to U.S.-based staff members at all levels. SRP and NDCP participants can direct notional account investments using the 401(k) Plan investing structure (excluding self-direct brokerage and our Company stock) as well as a variety of target date funds. Unlike a traditional pension plan, which provides a lifetime annuity that replaces a significant portion of a participant’s final pay, retirement benefits from our 401(k) Plan and SRP are based on the investment return on the staff member’s own investment elections, with the participant bearing the investment risk. The NDCP offers all U.S.-based staffPuerto Rico.

 

 

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Our Supplemental Retirement Plan, or SRP, is available to all 401(k) Plan participants and is designed to provide a “make whole” benefit to 401(k) Plan participants who have eligible compensation in excess of the Internal Revenue Code’s qualified plan compensation limit. The Company credits to the SRP a 10% contribution on eligible compensation in excess of the qualified plan compensation limit to represent the equivalent percentage of Company contributions that would have been made to the 401(k) Plan if the compensation had been eligible for deferral in the 401(k) Plan. For the same reason, the Company also credits to the SRP a 10% contribution on amounts voluntarily deferred by a participant into the Nonqualified Deferred Compensation Plan, or NDCP.

The SRP enables us to provide the same percentage of base salary and annual cash incentive award as a retirement contribution to U.S.-based staff members at all levels.

Earnings under the SRP and NDCP are market-based – there are no “above market” or guaranteed rates of returns offered in these plans. SRP and NDCP participants can direct notional account investments using the 401(k) Plan investing structure (excluding self-direct brokerage and our Company stock) plus a variety of target date funds. Unlike a traditional pension plan, which generally provides a lifetime annuity that replaces a portion of a participant’s final pay, retirement benefits from our 401(k) Plan and SRP are based on the investment return on the staff member’s own investment elections, with the participant bearing the risk of investment gains and losses.

The NDCP offers all U.S.-based staff members (including Puerto Rico) at director level and above the opportunity to defer eligible base salary andand/or annual cash incentive awards, up to maximum amounts typical at our peer group. We also have the discretion to make contributions to this plan, but we do not make such contributions on a regular basis.basis and did not make any contributions in 2021. We believe that offering the NDCP is appropriate because it provides executivesparticipants the opportunity to save for retirement in atax-effective fashion that is not readily available without our sponsorship.

Health Savings Account and Retiree Medical Savings Account Plan for all U.S.-based Staff Members

We offer a high deductible health plan and a health savings account that is generally available to U.S.-based (excluding Puerto Rico) staff

members. We also maintain a Retiree Medical Savings Account Plan available to U.S.-based (excluding Puerto Rico) staff members that allows all staff members to makeafter-tax deferrals to be used post-termination to reimburse them for reimbursement of eligible medical expenses. Under the Retiree Medical Savings Account Plan, the Company credits all eligible staff members with an annual contribution ($1,000) and makes a matching contribution equal to 50% of a staff member’s deferrals (up to(to a maximum match of $1,500 per year). Company credits can be accessed to reimburse eligible medical expenses of staff members who terminate having fulfilled the Company’s retirement criteria. We do not offer a traditional Company-paid retiree medical plan to our NEOs or other U.S.-based staff members.

 

 

TaxesTax and Accounting Standards

 

 

Tax Deductibility Under Section 162(m) of the Internal Revenue CodeStandards

Section 162(m) of the Internal Revenue Code places a $1 million limit on the amount of compensation that we may deduct for income tax purposes for any year with respect to compensation paid to “covered employees.” For tax years beginning after December 31, 2017, a covered employee includes an executive officer who holds the positions of either principal executive officer, or PEO, or principal financial officer, or PFO, at any time during the tax year, as well as an executive officer whose total compensation for the tax year is required to be reported to shareholders under the Securities Exchange Act of 1934 by reason of such employee being among the three highest compensated officers for the taxable year (excluding the PEO and PFO), regardless of whether the executive officer is serving at year end. In addition, if an individual is a covered employee for a tax year beginning after December 31, 2016, the individual remains a covered employee for all future years. Because of this“once-a-covered-employee,always-a-covered-employee” rule, the total number of our covered employees in 2019 is higher than in 2018.

In 2017, The Tax Cuts and Jobs Act, or Tax Reform Act, was signed into law effective for taxable years beginning after December 31, 2017. Prior to the Tax Reform Act, the $1 million limit did not apply to performance-based compensation, as defined. While the Tax Reform Act eliminated the exception for performance-based compensation, a transition rule continues the exception of performance-based

compensation provided pursuant to a written binding contract that was

in effect on November 2, 2017 and not modified in any material respect on or after such date. Under the transition rule, compensation related to the exercise of stock options granted on or before November 2, 2017 and compensation earned with respect to performance units granted prior to November 2, 2017, is anticipated to qualify for the exception for performance-based compensation, under the transition rules, provided that such contracts are not materially modified after that date. The cash tax impact for 2019 of compensation not being deductible due to the Section 162(m) limit is approximately $4.8 million, assuming the Company’s U.S. combined effective tax rate for 2019.

Accounting Standards

Financial Accounting Standards Board, or FASB, Accounting Standards Codification, or ASC, Topic 718 requires us to recognize an expense for the fair value of equity-based compensation awards. Grants of stock options, RSUs, and performance units under our LTI equity award plansprogram are accounted for under FASB ASC Topic 718. The Compensation Committee regularly considers the accounting implications of significant compensation decisions, especially in connection with decisions that relate to our LTI equity award plans and programs. For example, the Compensation Committee modified our Employee Stock Purchase Plan to make itnon-compensatory under the “safe harbor” provisions of the accounting rules and, therefore, we no longer recognize compensation expense under this plan. As accounting standards change, we may revise certain programs to appropriately align accounting expenses of our equity awards with our overall executive compensation philosophy and objectives.

 

 

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Executive Compensation Tables

 

 

 

 

 

Executive Compensation Tables

Summary Compensation Table

 

The following table sets forth summary information concerning the compensation awarded to, paid to, or earned by each of our Named Executive Officers, or NEOs.

 

  Name and Principal Position Year 

Salary

($)


(1)


Bonus

($)



Stock

Awards

($)

(1)

(2)

 

Option

AwardsBonus

($)


Stock   

Awards   

($)(3)(2)

 

Option   

Awards   

($)(3)

Non-Equity

Incentive Plan

Compensation

($)(4)

All Other   

Compensation   

($)(5)

Total

($)


(4)


All Other

Compensation

($)


(5)


Total

($)


           

Performance

Units and

Restricted

Stock Units

  

Stock

Options

  EIP       

 

  Robert A. Bradway

Chief Executive Officer

and President

 

 

 

 



 

2021
2020
2019

2018

2017

 

 



 

 

 

 



 

1,674,061   
1,647,538   
1,600,923

1,566,000

1,555,962

 

 



 

 

 

 



 

0


0


0

 

 



 

 

 

 



 

11,138,622   
10,079,676   
9,799,716

8,749,818

8,399,812

 

 



 

 

 

 



 

4,773,710   
4,319,993   
4,199,985

3,749,994

3,599,974

 

 



 

 

 

 



 

3,420,000   
3,495,000   
3,321,000

3,898,000

2,683,000

 

 



 

 

 

 



 

714,761   
589,201   
691,169

591,454

661,041

 

 



 

 

 

 



 

21,721,154
20,131,408
19,612,793

18,555,266

16,899,789

 

 



 

 

  Murdo Gordon

Executive Vice President,

President, Global

Commercial Operations

 

 

 

 



 

2021
2020
2019

2018

 

 



 

 

 

 



 

1,072,595   
1,055,520   
1,025,673

330,769

 

 



 

 

 

 



 

0

2,000,000
0
0

 

 



 

 

 

 



 

3,499,717   
2,869,779   
2,799,711

9,899,861

 

 



 

 

 

 



 

1,499,963   
1,229,977   
1,199,970

0

 

 



 

 

 

 



 

1,461,000   
1,493,000   
1,418,000

513,000

 

 



 

 

 

 



 

286,909   
327,774   
212,482

1,336,604

 

 



 

 

 

 



 

7,820,184
6,976,050
6,655,836

14,080,234

 

 

  David W. Meline

Executive Vice

President and Chief

Financial Officer

2019

2018

2017

999,049

977,746

970,769

0

0

0

2,799,711

2,799,925

2,449,878

1,199,970

1,199,995

1,049,990

1,382,000

1,623,000

1,116,000

292,840

260,102

271,651

6,673,570

6,860,768

5,858,288



 

 

  David M. Reese

Executive Vice President,

President, Research

and Development

 

 

 

 



 

2021
2020
2019

2018

 

 



1,065,127   
1,015,817   
974,433   





0
0
0





3,359,848   
2,869,779   
2,799,711   





1,439,975   
1,229,977   
1,199,970   





1,449,000   
1,436,000   
1,348,000   





271,734   
262,663   
215,811   





7,585,684
6,814,236
6,537,925



  Peter H. Griffith

Executive Vice President,

and Chief Financial Officer


2021
2020



1,014,963   
998,864   



0
0



2,799,665   
2,799,625   



1,199,979   
1,199,958   



1,382,000   
1,413,000   



267,427   
154,383   



6,664,034
6,565,830


  Esteban Santos

Executive Vice President,

Operations

 

 

 

 


 

974,433

697,5002021
2020

 

 


 

 

 

 


 

0

300,000994,246   
978,446   

 

 


 

 

 

 


 

2,799,711

3,029,7870
0

 

 


 

 

 

 


 

1,199,970

269,9663,324,824   
2,799,625   

 

 


 

 

 

 


 

1,348,000

913,0001,424,988   
1,199,958   

 

 


 

 

 

 


 

215,811

129,0191,354,000   
1,384,000   

 

 


 

 

 

 


 

6,537,925

5,339,272264,575   
229,624   

 

 

  Jonathan P. Graham

Executive Vice

President, General

Counsel and Secretary


 

 

 

 


 

2019

2018

20177,362,633
6,591,653

 

 

959,113

938,596

932,577

0

0

0

3,959,666

1,959,878

1,749,939

839,997

839,983

749,997

1,220,000

1,402,000

858,000

261,194

204,901

231,695

7,239,970

5,345,358

4,522,208


 

 

(1) 

Reflects base salary earned in eachbi-weekly pay period (or portion thereof) during each fiscal year beforepre-tax contributions and, therefore, includes compensation deferred under our qualified deferred compensation plan and nonqualified deferred compensation plan, or NDCP. Under payroll practices for salaried staff members of our U.S. entities, including our NEOs, base salary earned in a pay period is computed by dividing the annual base salary then in effect by 26, which is the number of fullbi-weekly pay periods in a year.

(2) 

For 2019,2021, reflects the grant date fair values of performance units for the 2019-20212021-2023 performance period and restricted stock units, or RSUs, granted during 20192021 determined in accordance with Accounting Standards Codification, or ASC, Topic 718 (see footnotes 6 and 7 to the “Grants of Plan-Based Awards” table for information on how these amounts were determined).

 

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Executive Compensation Tables

 

 

 

 

 

  

The number of units to be earned for the performance units granted during 20192021 is based on the average of our performance against annual operating performance measures established at the commencement of the three year performance period, with the payout on such measures modified up or down by our total shareholder return, or TSR, relative to the TSRs of the companies in the Standard & Poor’s 500 Index, or S&P 500, all computed over the performance period. These operating performance measures are performance conditions, as defined under ASC 718. The values shown in this table and the “Grants of Plan-Based Awards” table are based on probable outcomes of these performance conditions.conditions as of the grant date. The table below shows the grant date fair values of these performance unit awards: (1) if the maximum is achieved with regard to all of the operating performance measures which would result in an earnout of 170% based on the operating performance measures with the TSR market condition at target, with no increase or decrease based on the market condition; and (2) if the maximum is achieved with regard to all of the operating performance measures and maximum performance occurs under the TSR market condition which results in an additional 30% earnout, for total earned payout of 200% of performance units granted.

 

Fair Value of Performance Units for the 2019-2021 Performance Period 

Fair Value of Performance Units for the 2021-2023 Performance Period

Fair Value of Performance Units for the 2021-2023 Performance Period

 
Name  Based on the Maximum Performance
Regarding the  2019-2021 Operating
Performance Measures
   

Based on the Maximum Performance  

Regarding the Operating Performance  

Measures and Maximum Payout for the  

TSR Modifier  

   Maximum Performance of Operating Metrics
and Target TSR Performance ($)
   Maximum Performance of Operating Metrics  
and TSR Metrics ($)  
 

Robert A. Bradway

  

 

$11,899,532

 

  

 

$13,999,627  

 

  

 

13,525,545

 

  

 

15,912,406  

 

Murdo Gordon

  

 

$3,399,678

 

  

 

$3,999,732  

 

  

 

4,249,845

 

  

 

4,999,878  

 

David W. Meline

  

 

$3,399,678

 

  

 

$3,999,732  

 

David M. Reese

  

 

$3,399,678

 

  

 

$3,999,732  

 

  

 

4,079,719

 

  

 

4,799,699  

 

Jonathan P. Graham

  

 

$2,379,680

 

  

 

$2,799,624  

 

Peter H. Griffth

  

 

3,399,469

 

  

 

3,999,495  

 

Esteban Santos

  

 

4,037,187

 

  

 

4,749,782  

 

 

(3) 

For 2019,2021, reflects the grant date fair values ofnon-qualified stock options granted during 20192021 determined in accordance with ASC 718 (see footnote 8 to the “Grants of Plan-Based Awards” table for information on how these amounts were determined).

(4) 

Reflects amounts that were earned under our Executive Incentive Plan, or EIP, for 20192021 performance which were determined and paid in March 2020.2022. For a description of our EIP, see “Elements of Compensation and Specific Compensation Decisions—Annual Cash Incentive Awards” in our Compensation Discussion and Analysis.

(5) 

See the subsection “All Other Compensation—Perquisites and Other Compensation” immediately following these footnotes.

All Other Compensation—Perquisites and Other Compensation

 

Perquisites. The amounts reported reflect the aggregate incremental cost of perquisites and other personal benefits provided to our NEOs and are included in the “All Other Compensation” column of the “Summary Compensation Table.” The following table sets forth the perquisites provided to our NEOs in 2019.2021.

 

 Personal Use
of  Company
Aircraft
(1)
 Personal Use
of Company
Car and
Driver
(2)
 Personal
Financial
Planning
Services
 Other(3)   
 Personal Use
of  Company
Aircraft
(1)
 Personal Use
of Company
Car and
Driver
(2)
 Personal
Financial
Planning
Services
 Moving and Relocation
Expenses
(3)
 Other(4)   
Name 

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 Tax Gross-
Up($)
 

Aggregate

Incremental

Cost($)

 Total($)  

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 

Aggregate

Incremental

Cost($)

 Total($) 

Robert A. Bradway

 

 

106,505

 

 

 

4,306

 

 

 

15,000

 

 

 

0

 

 

 

0

 

 

 

16,173

 

 

 

141,984

 

 

 

166,559

 

 

 

2,725

 

 

 

15,000

 

 

 

13,450

 

 

 

197,734

 

Murdo Gordon

 

 

209

 

 

 

47

 

 

 

15,000

 

 

 

4,347

 

 

 

34,879

 

 

 

10,354

 

 

 

64,836

 

 

 

5,833

 

 

 

0

 

 

 

15,000

 

 

 

10,000

 

 

 

30,833

 

David W. Meline

 

 

204

 

 

 

3,113

 

 

 

15,000

 

 

 

0

 

 

 

0

 

 

 

12,758

 

 

 

31,075

 

David M. Reese

 

 

0

 

 

 

0

 

 

 

15,000

 

 

 

0

 

 

 

0

 

 

 

12,497

 

 

 

27,497

 

 

 

0

 

 

 

0

 

 

 

15,000

 

 

 

7,079

 

 

 

22,079

 

Jonathan P. Graham

 

 

209

 

 

 

76

 

 

 

15,000

 

 

 

0

 

 

 

0

 

 

 

10,221

 

 

 

25,506

 

Peter H. Griffith

 

 

0

 

 

 

14

 

 

 

15,000

 

 

 

10,000

 

 

 

25,014

 

Esteban Santos

 

 

0

 

 

 

0

 

 

 

15,000

 

 

 

12,200

 

 

 

27,200

 

 

(1) 

The aggregate incremental cost of use of our aircraft for personal travel by our NEOs is allocated entirely to the highest ranking NEO present on the flight (except foron-board catering costs which are allocated to each NEO present). If each NEO present on the flight is the same level, the aggregate incremental costs of use of our aircraft for personal travel is allocated to each NEO present. The aggregate incremental cost for personal use of our aircraft is calculated based on our variable operating costs, which include crew travel expenses,on-board catering, landing fees, trip-related hangar/parking costs, fuel, trip-related maintenance, and other smaller variable costs. In determining the incremental cost relating to fuel and trip-related maintenance, we applied an estimate derived from our average costs. We believe that the use of this methodology for 20192021 is a reasonably accurate method for calculating fuel and trip-related maintenance costs. Because our aircraft are used primarily for business travel, we do not include the fixed costs that do not change based on usage, such as pilots’ salaries, our aircraft purchase costs, and the cost of maintenance not related to trips. In December 2021, our Chief Executive Officer entered into a time sharing agreement with the Company to reimburse the Company for certain of his personal use.

(2)

The aggregate incremental cost for personal use of the car and driver provided by us is determined as the sum of the cost of fuel, driver overtime costs allocable to personal usage, and maintenance costs for the total number of personal miles driven. Personal miles include travel to and from work from home. As the cars are used primarily for business travel, fixed costs that would be incurred by us to operate the company cars for business use such as car lease or rental costs and driver salaries are not included.

(3)

Other expenses include:

(a)

Company contributions to non-profit charities designated by the executive in the amount of $10,000 for Messrs. Bradway, Gordon, Griffith, and Santos and $7,079 for Dr. Reese.

(b)

Executive physicals and expenses related to guests accompanying the NEOs on business travel.

 

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Executive Compensation Tables

 

 

 

 

 

(3)

Mr. Gordon agreed to relocate from New Jersey to Thousand Oaks, California to serve as Executive Vice President, Global Commercial Operations commencing in September 2018. The incremental cost of certain relocation benefits that were provided to Mr. Gordon in 2019 in connection with his relocation in accordance with our relocation policies, include:

(a)

$4,347 for reimbursed relocation-related travel expenses and miscellaneous other relocation expenses; and

(b)

$34,879 for taxgross-up payments on moving and relocation benefits provided.

(4)

Other expenses also include:

(a)

Company contributions tonon-profit charities designated by the executive in the amount of $9,984 for Mr. Bradway and $10,000 for Messrs. Gordon, Meline and Graham and Dr. Reese; and

(b)

Executive physicals, expenses related to guests accompanying the NEOs on business travel, gifts, and other expenses.

Other Compensation. The following table sets forth compensation for our NEOs in 20192021 incurred in connection with our 401(k) Retirement and Savings Plan, or 401(k) Plan, our NDCP, and our Supplemental Retirement Plan, or SRP. These amounts, along with the perquisites and other compensation discussed above, are included in the “All Other Compensation” column of the “Summary Compensation Table.” See “Nonqualified Deferred Compensation” below for a description of these plans.

 

Name    

Company Contributions to

401(k) Retirement and Savings

Plan($)

     

 

Company Credits to

Non-Qualified
Deferred
Compensation  Plan

     

 

Company Credits to

Supplemental

Retirement

Plan($)

     Total($)     Company Contributions to
401(k) Retirement and Savings
Plan($)
(1)
     

 

Company Credits to
Non-Qualified
Deferred
Compensation Plan

     

 

Company Credits to
Supplemental
Retirement
Plan($)

     Total($) 

Robert A. Bradway

    

 

28,000

 

    

 

0

 

    

 

521,185

 

    

 

549,185

 

    

 

29,878

 

    

 

0

 

    

 

487,149

 

    

 

517,027

 

Murdo Gordon

    

 

22,231

 

    

 

0

 

    

 

125,415

 

    

 

147,646

 

    

 

29,002

 

    

 

0

 

    

 

227,074

 

    

 

256,076

 

David W. Meline

    

 

28,000

 

    

 

0

 

    

 

233,765

 

    

 

261,765

 

David M. Reese

    

 

28,000

 

    

 

0

 

    

 

160,314

 

    

 

188,314

 

    

 

29,151

 

    

 

0

 

    

 

220,504

 

    

 

249,655

 

Jonathan P. Graham

    

 

28,000

 

    

 

0

 

    

 

207,688

 

    

 

235,688

 

Peter H. Griffith

    

 

29,076

 

    

 

0

 

    

 

213,337

 

    

 

242,413

 

Esteban Santos

    

 

29,000

 

    

 

0

 

    

 

208,375

 

    

 

237,375

 

(1)

Amounts over $29,000 reflect contributions in 2021 to correct an administrative error concerning 2020 contributions.

Grants of Plan-Based Awards

 

The following table sets forth summary information regarding all grants of plan-based awards made to our NEOs for the year ended December 31, 2021. All of our equity based awards were granted under the Amgen Inc. 2009 Equity Incentive Plan, as amended.

        

 

Estimated Future Payouts
Under Non-Equity Incentive
Plan Awards($)(2)

  

 

Estimated Future
Payouts Under Equity
Incentive Plan Awards
(# of units)(3)

  

All Other
Stock
Awards:
Number of
Shares of
Stock or
Units(#)(4)

  

All Other
Option
Awards:
Number of
Securities
Underlying
Options

(#)(5)

  

Exercise
or Base
Price of
Option
Awards

($/Sh)

  

Grant Date
Fair Value
of Stock
and Option
Awards($)

 

Name

 

Grant

Date

  

Approval

Date(1)

  Threshold  Target  Maximum  Threshold  Target        Maximum 
 

 

  

 

   

 

  EIP/GMIP  Performance Units  RSUs  Stock Options   

 

 

 

Robert A. Bradway

  3/2/2021   3/2/2021           (2)           (2)   12,246,250         
  4/30/2021   3/2/2021              (3)   31,240    62,480      7,956,203(6) 
  4/30/2021   3/2/2021          13,280     3,182,419(7) 
  

 

4/30/2021

 

 

 

  

 

3/2/2021

 

 

 

          

 

115,307

 

 

 

  

 

239.64

 

 

 

  4,773,710(8) 

 

Murdo Gordon

  3/2/2021   3/2/2021           (2)           (2)   7,347,750         
  4/30/2021   3/2/2021              (3)   9,816    19,632      2,499,939(6) 
  4/30/2021   3/2/2021          4,172     999,778(7) 
  

 

4/30/2021

 

 

 

  

 

3/2/2021

 

 

 

          

 

36,231

 

 

 

  

 

239.64

 

 

 

  1,499,963(8) 

 

David M. Reese

  3/2/2021   3/2/2021           (2)           (2)   7,347,750         
  4/30/2021   3/2/2021              (3)   9,423    18,846      2,399,850(6) 
  4/30/2021   3/2/2021          4,006     959,998(7) 
  

 

4/30/2021

 

 

 

  

 

3/2/2021

 

 

 

          

 

34,782

 

 

 

  

 

239.64

 

 

 

  1,439,975(8) 

 

Peter H. Griffith

  3/2/2021   3/2/2021           (2)           (2)   7,347,750         
  4/30/2021   3/2/2021              (3)   7,852    15,704      1,999,747(6) 
  4/30/2021   3/2/2021          3,338     799,918(7) 
  

 

4/30/2021

 

 

 

  

 

3/2/2021

 

 

 

          

 

28,985

 

 

 

  

 

239.64

 

 

 

  1,199,979(8) 

 

Esteban Santos

  3/2/2021   3/2/2021           (2)           (2)   7,347,750         
  4/30/2021   3/2/2021              (3)   9,325    18,650      2,374,891(6) 
  4/30/2021   3/2/2021          3,964     949,933(7) 
   

 

4/30/2021

 

 

 

  

 

3/2/2021

 

 

 

                                  

 

34,420

 

 

 

  

 

239.64

 

 

 

  1,424,988(8) 

(1)

Reflects the date on which the grants were approved by the Compensation and Management Development Committee, or Compensation Committee.

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Executive Compensation Tables

 

 

 

 

 

Grants of Plan-Based Awards

The following table sets forth summary information regarding all grants of plan-based awards made to our NEOs for the year ended December 31, 2019. All of our equity based awards were granted under the Amgen Inc. 2009 Equity Incentive Plan, as amended.

        

 

Estimated Future Payouts
UnderNon-Equity Incentive
Plan Awards($)(2)

  

 

Estimated Future Payouts
Under Equity Incentive
Plan Awards (# of units)(3)

  

All Other
Stock
Awards:
Number of
Shares of
Stock or
Units(#)(4)

  

All Other
Option
Awards:
Number of
Securities
Underlying
Options

(#)(5)

  

Exercise
or Base
Price of
Option
Awards

($/Sh)

  

Grant Date
Fair Value
of Stock
and Option
Awards($)

 

 

Name

 

Grant

Date

  

Approval

Date(1)

  Threshold  Target  Maximum  Threshold  Target        Maximum 
        EIP/GMIP  Performance Units  RSUs  Stock Options    

 

Robert A. Bradway

  3/6/19   3/6/19           (2)           (2)   11,285,000         
  5/3/19   3/6/19              (3)   37,154    74,308      6,999,814(6) 
  5/3/19   3/6/19          15,791     2,799,902(7) 
  

 

5/3/19

 

 

 

  

 

3/6/19

 

 

 

          

 

137,840

 

 

 

  

 

177.31

 

 

 

  4,199,985(8) 

 

Murdo Gordon

  3/6/19   3/6/19           (2)           (2)   6,771,000         
  5/3/19   3/6/19              (3)   10,615    21,230      1,999,866(6) 
  5/3/19   3/6/19          4,511     799,845(7) 
  

 

5/3/19

 

 

 

  

 

3/6/19

 

 

 

          

 

39,382

 

 

 

  

 

177.31

 

 

 

  1,199,970(8) 

 

David W. Meline

  3/6/19   3/6/19           (2)           (2)   6,771,000         
  5/3/19   3/6/19              (3)   10,615    21,230      1,999,866(6) 
  5/3/19   3/6/19          4,511     799,845(7) 
  

 

5/3/19

 

 

 

  

 

3/6/19

 

 

 

          

 

39,382

 

 

 

  

 

177.31

 

 

 

  1,199,970(8) 

 

David M. Reese

  3/6/19   3/6/19           (2)           (2)   6,771,000         
  5/3/19   3/6/19              (3)   10,615    21,230      1,999,866(6) 
  5/3/19   3/6/19          4,511     799,845(7) 
  

 

5/3/19

 

 

 

  

 

3/6/19

 

 

 

          

 

39,382

 

 

 

  

 

177.31

 

 

 

  1,199,970(8) 

 

Jonathan P. Graham

  3/6/19   3/6/19           (2)           (2)   4,514,000         
  5/3/19   3/6/19              (3)   7,430    14,860      1,399,812(6) 
  5/3/19   3/6/19          3,158     559,945(7) 
  11/1/19   10/21/19          9,176     1,999,909(7) 
   

 

5/3/19

 

 

 

  

 

3/6/19

 

 

 

                                  

 

27,568

 

 

 

  

 

177.31

 

 

 

  839,997(8) 

(1)

Reflects the date on which the grants were approved by the Compensation Committee.

(2) 

Represents awards to our NEOs made under our EIP. For our EIP participants, the “maximum” amounts shown in the table above reflect the largest possible payments under our EIP for the 20192021 performance period, based onnon-Generally Accepted Accounting Principles, ornon-GAAP, net income, as defined for the EIP and reported and reconciled in Appendix B. There are no thresholds or targets under the EIP. The EIP provides that the Compensation Committee may use “negative discretion” to award any amount that does not exceed the maximum. Consistent with its practice since the EIP was approved by our stockholders, the Compensation Committee employed thepre-established Company performance goals under our Global Management Incentive Plan, or GMIP, as illustrated in the table below, in determining the actual amounts awarded under the EIP in 2019.2021.

Our 2021 Company performance goals under the GMIP were financial and operating performance goals weighted as follows: (1) Deliver Results (60%)—30% Revenues and 30% LOGONon-GAAP Net Income (as reported and reconciled in Appendix B); (2) Progress Innovative Pipeline (30%); and (3) Deliver Annual Priorities (10%). There are no payouts for below-threshold performance on any of our Company financial performance goals. Threshold performance on our “Progress Innovative Pipeline” goals results in 50% earned for those metrics. Certain measurements of performance for the non-financial metrics are more subjective in nature and could result in a very small payout percentage (less than 1% of an annual cash incentive award) and, as such, no threshold amounts are shown in the table. The 2021 Company performance goals at target and maximum payout levels, which are based on a multiple of salary, are shown in the table below. Maximum performance under all of the performance metrics results in 225% of target payout opportunity being earned. The actual amounts awarded under our Company performance goals for 2021 were based on achievement of 136.8% performance against target and are reported as “Non-Equity Incentive Plan Compensation” in our “Summary Compensation Table” and are shown in the table below. For a description of our pre-established Company performance goals and the use of the GMIP in the Compensation Committee’s exercise of negative discretion see “Elements of Compensation and Specific Compensation Decisions—ï 2020 Proxy StatementAnnual Cash Incentive Awards    69” in our Compensation Discussion and Analysis.


Executive Compensation Tables

Our 2019 Company performance goals under the GMIP were financial and operating performance goals weighted as follows: (1) Deliver Results (60%)—30% Revenues and 30%Non-GAAP Net Income (as reported and reconciled in Appendix B); (2) Progress Innovative Pipeline (30%); and (3) Deliver Annual Priorities (10%). There are no payouts for below-threshold performance on any of our Company financial performance goals. Threshold performance on our “Progress Innovative Pipeline” goals results in 50% earned for those metrics. Certain measurements of performance for thenon-financial metrics are more subjective in nature and could result in a very small payout percentage (less than 1% of an annual cash incentive award) and, as such, no threshold amounts are shown in the table. The 2019 Company performance goals derived target and maximum payout levels, which are based on a multiple of salary, are shown in the table below. Maximum performance under all of the performance metrics results in 225% of target being earned. The actual amounts awarded under our Company performance goals are based on achievement of 138.9% performance against target and are reported as“Non-Equity Incentive Plan Compensation” in our “Summary Compensation Table” and are shown in the table below. For a description of ourpre-established Company performance goals and the use of the GMIP in the Compensation Committee’s exercise of negative discretion see “Elements of Compensation and Specific Compensation Decisions—Annual Cash Incentive Awards” in our Compensation Discussion and Analysis.

 

  

Estimated Possible Payouts Under

    Non-Equity Incentive Plan Awards($)    

      

 

  

Non-Equity
Incentive Plan

  Compensation($)  

 
  

Estimated Possible Payouts Under

    Non-Equity Incentive Plan  Awards($)    

    

Non-Equity
Incentive Plan

  Compensation($)  

 
Name  Threshold     Target     Maximum   Actual   Threshold     Target     Maximum       

 

  Actual 

Robert A. Bradway

  

 

 

    

 

2,390,769

 

    

 

5,379,230   

 

   

 

3,321,000        

  

 

 

    

 

2,499,738

 

    

 

5,624,411   

 

      

 

3,420,000        

 

Murdo Gordon

  

 

 

    

 

1,021,154

 

    

 

2,297,597   

 

   

 

1,418,000        

  

 

 

    

 

1,067,742

 

    

 

2,402,420   

 

      

 

1,461,000        

 

David W. Meline

  

 

 

    

 

994,646

 

    

 

2,237,954   

 

   

 

1,382,000        

David M. Reese

  

 

 

    

 

970,139

 

    

 

2,182,813   

 

   

 

1,348,000        

  

 

 

    

 

1,059,039

 

    

 

2,382,838   

 

      

 

1,449,000        

 

Jonathan P. Graham

  

 

 

    

 

878,494

 

    

 

1,976,612   

 

   

 

1,220,000        

Peter H. Griffith

  

 

 

    

 

1,010,373

 

    

 

2,273,339   

 

      

 

1,382,000        

 

Esteban Santos

  

 

 

    

 

989,750

 

    

 

2,226,938   

 

       

 

1,354,000        

 

 

(3) 

Reflects estimated payouts regarding performance units granted during 20192021 for the 2019-20212021-2023 performance period for NEOs. The number of units granted (which equals the target number of units of the award) will be multiplied by a payout percentage, which can range from 0% to 200%, to determine the number of units earned by the participant at the end of the performance period. Shares of our Common Stock will be issued on aone-for-one basis for each performance unit earned.

For all the NEOs, the payout percentage for the 2021-2023 performance period is earned based on two operating measures, with the total that can be earned under such operating measures ranging from 30% to 170%, which is then modified up or down by up to 30 percentage points based on our relative TSR performance ranking. The non-GAAP operating measures are: (1) annual earnings per share; and (2) annual return on invested capital, or ROIC. Each of the operating measures are measured against pre-established goals for every year in the 2021-2023 performance period, which runs from January 1, 2021 through December 31, 2023. All goals are set at the commencement of the three-year performance period. Each applicable operating measure is weighted equally (one-half per measure) to determine the total operating measure percentage for that year. At the end of the performance period, the final annual operating performance percentages for each of the three years are averaged to determine the score for the three-year performance period. The TSR modifier is based on how the TSR of our Common Stock ranks relative to the TSRs of the companies that are listed in the S&P 500, as defined (the Reference Group), over the period from the date of grant through the end of the performance period. If the rank of the TSR of our Common Stock equals or exceeds the 75th percentile or equals or is less than the 25th percentile, the TSR modifier increases or decreases the payout by 30 percentage points, respectively. If the TSR of our Common Stock is at the 50th percentile, the TSR modifier is zero. Linear interpolation is used to determine the TSR modifier if the rank of the TSR of our Common Stock falls between these percentiles. If our absolute TSR over the performance period is less than 0, then the modifier cannot be greater than 0.

For all the NEOs, the payout percentage for the 2019-2021 performance period is earned based on two operating measures, with the total of such operating measures ranging from 30% to 170%, which is then modified up or down by up to 30 percentage points based on our relative TSR performance ranking. Thenon-GAAP

All performance units accrue dividend equivalents deemed reinvested in shares and that are payable in shares only to the extent and when the underlying performance units are earned. For more information, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis. operating measures are: (1) annual earnings per share for 2019, 2020 and 2021; and (2) annual return on invested capital, or ROIC, for 2019, 2020 and 2021. Each of the operating measures are measured againstpre-established goals for every year in the 2019-2021 performance period, which runs from January 1, 2019 through December 31, 2021. All goals are set at the commencement of the three-year performance period. Each applicable operating measure is weighted equally(one-half per measure) to determine the total operating measure percentage for that year. At the end of the performance period, the final annual operating performance percentages for each of the three years are averaged to determine the score for the three-year performance period. The TSR modifier is based on how the TSR of our Common Stock ranks relative to the TSRs of the companies that are listed in the S&P 500, as defined (the Reference Group), over the period from the date of grant through the end of the performance period. If the rank of the TSR of our Common Stock equals or exceeds the 75th percentile or equals or is less than the 25th percentile, the TSR modifier increases or decreases the payout by 30 percentage points, respectively. If the TSR of our Common Stock is at the 50th percentile, the TSR modifier is zero. Linear interpolation is used to determine the TSR modifier if the rank of the TSR of our Common Stock falls between these percentiles. If our absolute TSR over the performance period is less than 0, then the modifier cannot be greater than 0.

All performance units accrue dividend equivalents deemed reinvested in shares and that are payable in shares only to the extent and when the underlying performance units are earned. For more information, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis. All 2019 operating measures with respect to the 2019-2021 performance period discussed above are reported and reconciled in Appendix B.

(4) 

Reflects the RSUs granted during 2019, including the annual grant of RSUs2021 to our NEOs and a grant to Mr. Graham in connection with his promotion to Executive Vice President, General Counsel and Secretary.NEOs. RSUs accrue dividend equivalents that are deemed reinvested in shares and payable only to the extent and when the underlying RSUs vest and are issued to the recipient.

(5) 

Reflects the 20192021 annual grant ofnon-qualified stock options to our NEOs.

(6) 

Reflects the grant date fair values of performance units granted to our NEOs for the 2019-20212021-2023 performance period determined in accordance with ASC 718, based on the number of performance units granted multiplied by: (i) 100% which is the operating measure percentage earnout based on the probable outcomes of financial performance measures over the three-year performance period as of the grant date; and (ii) the grant date fair value per unit of $188.40,$254.68 which reflects the impact of the TSR modifier of $11.09$15.04 per share, which is a market condition. The grant date fair value per unit was calculated using a payout simulation model with the following key assumptions: risk-free interest rate of 2.3%0.3%; volatility of the price of our Common Stock of 22.1%29.3%; the closing price of our Common Stock on the grant date of $177.31$239.64 per share; volatilities of the prices of the stocks of the Reference Group; and the correlations of returns of our Common Stock and the stocks of the Reference Group to simulate TSRs and their resulting impact on the payout percentages based on the contractual terms of the performance units.

(7) 

Reflects the grant date fair values of RSUs granted during 20192021 determined in accordance with ASC 718 based on the number of RSUs granted multiplied by the grant date fair values per unit of $177.31 and $217.95 on May 3 and November 1, respectively.$239.64. Because these RSUs accrue dividend equivalents during the vesting period, the grant date fair value per unit equals the closing price of our Common Stock on the grant date.

(8) 

Reflects the grant date fair values of stock options granted during 20192021 determined in accordance with ASC 718 based on the number of options granted multiplied by the grant date fair value per option of $30.47.$41.40. The grant date fair value of an option was determined using a Black-Scholes option valuation model with the following key assumptions: risk-free interest rate of 2.4%1.0%; expected life of 5.85.7 years; expected volatility of the price of our Common Stock of 23.5%25.9%; expected dividend yield of 3.1%2.9%; and the exercise price of $177.31.$239.64.

 

7076    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Executive Compensation Tables

 

 

 

 

 

Outstanding Equity Awards at FiscalYear-End

 

The following table sets forth summary information regarding the outstanding equity awards at December 31, 20192021 granted to each of our NEOs.

 

   Option Awards   Stock Awards 
  Name  

Number of

Securities

Underlying

Unexercised

Options

Exercisable

(#)

   

Number of

Securities

Underlying

Unexercised

Options

Unexercisable

(#)

   

Option

Exercise

Price

($/Option)

   

Option

Expiration

Date(1)

   

Number of

Shares or

Units of

Stock That

Have Not

Vested

(#)(2)

   

Market Value

of Shares or

Units of Stock

That Have Not

Vested

($)(3)

   

Equity Incentive

Plan Awards:

Number of

Unearned Shares,

Units or Other

Rights That Have

   Option Awards   Stock Awards 
  Name  

Number of

Securities

Underlying

Unexercised

Options

Exercisable

(#)

   

Number of

Securities

Underlying

Unexercised

Options

Unexercisable

(#)

   

Option

Exercise

Price

($/Option)

   

Option

Expiration

Date(1)

   

Number of

Shares or

Units of

Stock That

Have Not

Vested

(#)(2)

   

Market Value

of Shares or

Units of Stock

That Have Not

Vested

($)(3)

   

Equity Incentive

Plan Awards:

Number of

Unearned Shares,

Units or Other

Rights That Have

Not Vested

(#)

   

Equity Incentive

Plan Awards:

Market or Payout

Value of Unearned

Shares, Units or

Other Rights That

Have Not Vested

($)(3)

 
   

Stock Options(1)

 

   

Restricted Stock Units and

Dividend Equivalents

 

   

Performance Units and Dividend

Equivalents

 

 

  

Robert A. Bradway

  

0

 

137,840

 

177.31

115,307
 

5/3/29

 

46,925

239.64
 

11,312,210

 

75,912

(4)

4/30/2031
 

18,300,106

43,242
9,728,15331,984(4)7,195,440
   0    108,444102,031    177.46236.36    4/27/285/5/2030        69,61330,446(5)    16,781,6066,849,437 
   43,13645,487    87,58292,353    162.60177.31    5/1/273/2029        55,68334,964(6)    13,423,5017,865,851 
   79,05671,573    40,72636,871    156.35177.46    5/3/264/27/2028         
   73,500130,718    0    54.69162.60    4/25/215/1/2027         
   127,000119,782    0    58.43156.35    4/26/205/3/2026         

  Murdo Gordon

   0    39,38236,231239.644/30/203111,2012,519,88910,049(4)2,260,724
029,050236.365/5/20308,668(5)1,950,040
12,99626,386    177.31    5/3/2920299,989(6)2,247,225

  David M. Reese

0    27,68434,782    6,673,782239.64    21,6884/30/203116,2163,648,1149,647(4)    5,228,3262,170,286 
029,050236.365/5/20308,668(5)1,950,040
12,99626,386177.315/3/20299,989(6)2,247,225
5,1522,655177.464/27/2028        
   36,703(5)8,714 8,847,992

  David W. Meline

   0    39,382177.31162.60    5/3/2914,1493,410,89921,688(4)5,228,326
034,702177.464/27/281/2027       22,275(5)5,369,834
12,58125,545162.605/1/27  16,240(6)3,914,977
   25,1538,711    12,9590    156.35    5/3/262026         

  David M. ReesePeter H. Griffith

   0    39,38228,985    177.31239.64    5/3/294/30/2031    23,63720,111    5,698,1724,524,372    21,6888,039(4)    5,228,3261,808,534 
   0    7,80728,341    177.46236.36    4/27/285/5/2030        5,0108,456(5)    1,207,7611,902,346

  Esteban Santos

034,420239.644/30/203111,6862,628,9999,547(4)2,147,789 
   2,8750    5,83928,341    162.60236.36    5/1/275/2030        3,7118,456(6)(5)    894,6111,902,346 
   5,74911,371    2,96223,089    156.35177.31    5/3/2620298,740(6)1,966,238
16,0328,259177.464/27/2028         
   2,30030,501    0    54.69162.60    4/25/215/1/2027         
   1,4808,711    058.434/26/20

  Jonathan P. Graham

027,568177.315/3/2919,1094,606,60715,180(4)3,659,443
024,291177.464/27/2815,593(5)3,759,005
8,98618,247162.605/1/2711,600(6)2,796,412
16,5298,516    156.35    5/3/262026         
                                         

 

(1) 

In general, stock options expire on the tenth anniversary of their grant date. If a retirement-eligible staff member retires, their stock options continue to vest and expire on the earlier of: (i) the fifth anniversary of their retirement date; or (ii) the end of the grant term. No stock options were granted to NEOs during 2012 through 2015.

(2) 

The following table shows the vesting of RSUs and related accrued dividend equivalents (rounded down to the nearest whole number of units) outstanding as of December 31, 2019.2021. RSUs accrue dividends that are deemed reinvested in shares and payable only when, and to the extent that, the underlying RSUs vest and are issued to the participant.

 

  Granted on   Granted on 
Name  

November 1,

2019(a)

   

May 3,

2019(a)

   

November 2,

2018(b)

   

April 27,

2018(a)

   

May 1,

2017(c)

   

May 3,

2016(d)

   April 30,
2021
(a)
   May 5,
2020
(a)
   November 1,
2019
(b)
   May 3,
2019
(b)
   November 2,
2018
(c)
   April 27,
2018
(c)
 

Robert A. Bradway

  

 

0

 

  

 

16,132

 

  

 

0

 

  

 

14,810

 

  

 

10,681

 

  

 

5,302

 

  

 

13,596

 

  

 

12,832

 

  

 

0

 

  

 

11,470

 

  

 

0

 

  

 

5,344

 

Murdo Gordon

  

 

0

 

  

 

4,608

 

  

 

23,076

 

  

 

0

 

  

 

0

 

  

 

0

 

  

 

4,271

 

  

 

3,653

 

  

 

0

 

  

 

3,277

 

  

 

0

 

  

 

0

 

David W. Meline

  

 

0

 

  

 

4,608

 

  

 

0

 

  

 

4,739

 

  

 

3,115

 

  

 

1,687

 

David M. Reese

  

 

0

 

  

 

4,608

 

  

 

13,303

 

  

 

1,066

 

  

 

4,274

 

  

 

386

 

  

 

4,101

 

  

 

3,653

 

  

 

0

 

  

 

3,277

 

  

 

4,801

 

  

 

384

 

Jonathan P. Graham

  

 

9,232

 

  

 

3,226

 

  

 

0

 

  

 

3,316

 

  

 

2,226

 

  

 

1,109

 

Peter H. Griffith

  

 

3,417

 

  

 

3,564

 

  

 

13,130

 

  

 

0

 

  

 

0

 

  

 

0

 

Esteban Santos

  

 

4,058

 

  

 

3,564

 

  

 

0

 

  

 

2,867

 

  

 

0

 

  

 

1,197

 

 

 (a) 

Scheduled to vest at a rate of approximately 33%, 33%, and 34% on the second, third, and fourth anniversaries of the grant date, respectively.

 
 (b)

For Mr. Gordon, scheduled to vest at a rate of approximately 54% and 46% on the second and third anniversaries of the grant date, respectively; and for Dr. Reese, scheduled to vest at a rate of approximately 33%, 33%, and 34% on the second, third, and fourth anniversaries of the grant date, respectively.

(c) 

Scheduled to vest in approximately equal installmentsamounts on each of the third and fourth anniversaries of the grant date.

 
 (d)(c)

Scheduled to vest on the fourth anniversary of the grant date.

 
(3)

The market values of RSUs and performance units (and related dividend equivalents) were calculated by multiplying the number of RSUs outstanding or the number of performance units as determined in accordance with Securities and Exchange Commission, or SEC, rules and footnotes 4 through 6 below, as applicable, by the closing price of our Common Stock on December 31, 20192021 ($241.07)224.97).

 

LOGO  ï 20202022 Proxy Statement    7177


    

 

 

 

 

Executive Compensation Tables

 

 

 

 

 

(4) 

Reflects the sum of the number of performance units granted for the 2019–20212021–2023 performance period (January 1, 20192021 to December 31, 2021)2023) and the related dividend equivalents accrued through December 31, 2019,2021, multiplied by the maximumtarget payout percentage of 200%100%. As required by SEC rules, the maximumtarget payout percentage is disclosed in the table because the estimated payout percentage as of December 31, 2019 exceeds the target payout of 100% of the performance units granted (based on the sum of: (1) the estimated outcomes of our operating measures to be achieved; and (2) the TSR modifier based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 3, 2019 grant date to December 31, 2019). The number of dividend equivalents multiplied by the 200% payout percentage (rounded down to the nearest whole number of units) included in the table above are as follows: 1,604 units for Mr. Bradway; 458 units for Messrs. Gordon and Meline and Dr. Reese; and 320 units for Mr. Graham. Dividend equivalents are only paid when and to the extent the underlying performance units are earned.

(5)

Reflects the sum of the number2021 is greater than a threshold level of performance, units granted for the 2018–2020 performance period (January 1, 2018 to December 31, 2020) and the related dividend equivalents accrued through December 31, 2019, multiplied by the maximum payout percentage of 200%. As required by SEC rules, the maximum payout percentage is disclosed in the table because the estimated payout percentage as of December 31, 2019 is greaterbut less than the target payout of 100% of the performance units granted (based on the sum of: (1) the estimated outcomes of our operating measures to be achieved; and (2) the TSR modifier based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the April 27, 201830, 2021 grant date (or the November 2, 2018 grant date with respect to Mr. Gordon) to December 31, 2019)2021). The number of dividend equivalents multiplied by the 200%100% payout percentage (rounded down to the nearest whole number of units) included in the table above are as follows: 3,399744 units for Mr. Bradway; 1,305233 units for Mr. Gordon; 1,087 units for Mr. Meline; 244224 units for Dr. Reese; and 761187 units for Mr. Graham.Griffith; and 222 units for Mr. Santos. Dividend equivalents are only paid when and to the extent the underlying performance units are earned.

(5)

Reflects the sum of the number of performance units granted for the 2020–2022 performance period (January 1, 2020 to December 31, 2022) and the related dividend equivalents accrued through December 31, 2021, multiplied by the maximum payout percentage of 100%. As required by SEC rules, the target payout percentage is disclosed in the table because the estimated payout percentage as of December 31, 2021 is greater than the threshold level of performance, but less than the target payout of 100% of the performance units granted (based on the sum of: (1) the estimated outcomes of our operating measures to be achieved; and (2) the TSR modifier based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 5, 2020 grant date to December 31, 2021). The number of dividend equivalents multiplied by the 100% payout percentage (rounded down to the nearest whole number of units) included in the table above are as follows: 1,539 units for Mr. Bradway; 438 units for Mr. Gordon and Dr. Reese; and 427 units for Messrs. Griffith and Santos.Dividend equivalents are only paid when and to the extent the underlying performance units are earned.

(6)

Reflects the number of performance units granted for the 2017-20192019-2021 performance period (January 1, 20172019 to December 31, 2019)2021), and related dividend equivalents accrued through December 31, 2019,2021, multiplied by the actual payout percentage of 153.7%86.8%, which is based on our actual performance under our operating measures of 103.7% plus91.6% and the relative TSR percentage modifier of +50-4.8% percentage points based on our actual TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 1, 20173, 2019 grant date to December 31, 2019.2021. The number of dividend equivalents multiplied by the 153.7%86.8% payout percentage noted above (rounded down to the nearest whole number of units) included in the table above are as follows: 4,1272,714 units for Mr. Bradway; 1,203775 units for Mr. Meline; 275 units forGordon and Dr. Reese; and 859678 units for Mr. Graham.Santos. Since these performance units were paid in 2020,2022, they will be reflected in the “Option Exercises and Stock Vested” table as vested shares in next year’s proxy statement.

The estimated payouts of the performance units described above are disclosed in the limited context of our executive compensation program and should not be understood to be statements of our expectations of our stock price or estimates of results or other guidance. We specifically caution investors not to apply these statements to other contexts.

Option Exercises and Stock Vested

 

The following table summarizes the exercise of options, the vesting of RSUs, and the payment of performance units earned for the 2016-20182018-2020 performance period (and related dividend equivalents, as applicable) for each of our NEOs during the year ended December 31, 2019.2021. The RSUs and performance units vested and converted to one share of our Common Stock for each vested RSU and performance unit. The 2016-20182018-2020 performance units had a performance period from January 1, 20162018 through December 31, 20182020 and became payable as shares upon certification by our Compensation Committee in March 2019.2021.

 

 Option Awards     Stock Awards  Option Awards     Stock Awards 
Name 

Number of Securities

Acquired on Exercise (#)

     

Value Realized on

Exercise ($)(1)

     

Number of Shares

Acquired on Vesting (#)

     Value Realized
on Vesting ($)
(2)
  Number of Securities
Acquired on Exercise (#)
(1)
     Value Realized on
Exercise ($)
(2)
     Number of Shares
Acquired on Vesting (#)
     Value Realized
on Vesting  ($)
(3)
 

Robert A. Bradway

 

 

0

 

    

 

0

 

    

 

66,183

 

    

 

12,559,278

 

 

 

73,500

 

    

 

13,297,620

 

    

 

55,454

 

    

 

13,557,835

 

Murdo Gordon

 

 

0

 

    

 

0

 

    

 

12,322

 

    

 

2,685,656

 

 

 

0

 

    

 

0

 

    

 

30,965

 

    

 

7,171,502

 

David W. Meline

 

 

0

 

    

 

0

 

    

 

20,799

 

    

 

3,948,170

 

David M. Reese

 

 

0

 

    

 

0

 

    

 

6,475

 

    

 

1,211,364

 

 

 

2,300

 

    

 

419,796

 

    

 

11,633

 

    

 

2,669,897

 

Jonathan P. Graham

 

 

0

 

    

 

0

 

    

 

26,460

 

    

 

4,984,294

 

Peter H. Griffith

 

 

0

 

    

 

0

 

    

 

6,413

 

    

 

1,327,462

 

Esteban Santos

 

 

0

 

    

 

0

 

    

 

12,615

 

    

 

3,083,727

 

 

(1) 

NoThese amounts represent the exercise of stock options granted in April 2011 and expiring in April 2021. For Mr. Bradway and Dr. Reese, 47,527 and 1,147 shares, respectively, were exercisedwithheld by NEOs in 2019.the Company to cover the option exercise price and tax withholding.

(2)

The value shown is based on the stock options exercised multiplied by the difference between the market price of the underlying securities at exercise and the stock option exercise price.

(3) 

The value shown is the closing price of a share of our Common Stock on the business days immediately prior to the vesting dates of RSUs and to the payment date for the performance units, as applicable, multiplied by the number of units vested/paid, including cash received in lieu of fractional dividend equivalents.

 

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Executive Compensation Tables

 

 

 

 

 

Nonqualified Deferred Compensation

 

The following table sets forth summary information regarding aggregate contributions to and account balances under our SRP and NDCP for, and as of, the year ended December 31, 2019.2021. There were no withdrawals by any of the NEOs in 2019.2021.

 

Name    

 

2019 Employee

Contributions

($)(1)

     

 

2019 Company

Contributions

($)(2)

     

2019 Earnings

($)(3)

     

 

Balance as of  

12/31/19  

($)(4)  

     

 

2021 Employee

Contributions

($)(1)

     

 

2021 Company

Contributions

($)(2)

     

 

2021 Earnings

($)(3)

     

 

Balance as of  

12/31/21  

($)(4)  

 

Robert A. Bradway

    

 

584,700

 

    

 

521,185

 

    

 

2,079,103

 

    

 

16,086,924  

 

    

 

524,250

 

    

 

487,149

 

    

 

1,355,765

 

    

 

21,292,390

 

Murdo Gordon

    

 

98,269

 

    

 

125,415

 

    

 

195,032

 

    

 

1,358,945  

 

    

 

149,300

 

    

 

227,074

 

    

 

164,329

 

    

 

2,925,260

 

David W. Meline

    

 

0

 

    

 

233,765

 

    

 

508,944

 

    

 

6,485,612  

 

David M. Reese

    

 

0

 

    

 

160,314

 

    

 

218,901

 

    

 

1,221,722  

 

    

 

0

 

    

 

220,504

 

    

 

56,845

 

    

 

1,768,687

 

Jonathan P. Graham

    

 

291,892

 

    

 

207,688

 

    

 

720,472

 

    

 

4,107,089  

 

Peter H. Griffith

    

 

1,130,400

 

    

 

213,337

 

    

 

40,856

 

    

 

2,291,006

 

Esteban Santos

    

 

0

 

    

 

208,375

 

    

 

342,976

 

    

 

4,255,839

 

 

(1) 

Reflects the portions of the annual cash incentive awards deferred and contributed to the NDCP in the amount of $584,700$524,250 by Mr. Bradway; $149,300 by Mr. Gordon; and $200,000$1,130,400 by Mr. Griffith. The amounts for Messrs. Bradway, Gordon and Graham, respectively, thatGriffith were included in the“Non-Equity Incentive Plan Compensation” column of the “Summary Compensation Table” in 2018, the year they were earned. Also reflects a portion of salaries deferred and contributed to the NDCP in the amount of $98,269 and $91,892 by Messrs. Gordon and Graham, that were included in the “Salary” column of the “Summary Compensation Table” in 2019,2020, the year they were earned.

(2) 

Reflects credits to the SRP. With respect to Mr. Gordon,Griffith, the unvested portion of his SRP contribution vests on the third anniversary of his hire date.date of October 23, 2019. See footnote 4.

(3) 

Reflects earnings in the NDCP and SRP for 2019.2021.

(4) 

Reflects balances in the NDCP and SRP on December 31, 2019.2021. All amounts are vested, except amounts with respect to: $747,606, $708,954, and $562,280 for Messrs. Gordon, Meline, and Graham, respectively, related to Company contributions in their NDCP accounts and related earnings and losses and $128,221$132,273 for Mr. GordonGriffith related to Company contributions and related gains and losses to his SRP account. These balances include the following aggregate amounts that are reported as compensation in this proxy statement in the “Summary Compensation Table” in 2019, 2018,2021, 2020, and 2017: $2,398,6732019: $2,497,719 for Mr. Bradway; $1,226,954$1,192,204 for Mr. Gordon; $840,573 for Mr. Meline; $236,333$587,815 for Dr. Reese; and $924,008$2,091,153 for Mr. Graham.Griffith; and $491,706 for Mr. Santos.

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Executive Compensation Tables

General Provisions of the Supplemental Retirement Plan and Nonqualified Deferred Compensation Plan

 

The SRP is designed to provide a “make-whole” benefit to 401(k) Plan participants who have eligible compensation in excess of the Internal Revenue Code’s qualified plan compensation limit. The Company credits to the SRP a 10% contribution on such compensation to represent the equivalent percentage of Company contributions that would have been made to the 401(k) Plan if the compensation had been eligible for deferral into the 401(k) Plan. For the same reason, the Company also credits to the SRP a 10% contribution on amounts voluntarily deferred by a participant into the NDCP. No “above market” crediting rates are offered under the SRP and employee contributions to the SRP are not permitted.

The SRP and the NDCP are unfunded plans for tax purposes and for purposes of Title I of the Employee Retirement Income Security Act of 1974, as amended. Deferred amounts are our general unsecured obligations and are subject to ouron-going ongoing financial solvency. We have established a grantor trust (aso-called “rabbi” trust) for the purpose of accumulating funds to assist us in satisfying our obligations under the NDCP. Earnings on amounts contributed to our SRP and NDCP, like our

401(k) Plan, are based on participant selections among the deemed investment

options selected by a committee of our executives. This committee has the sole discretion to discontinue, substitute, or add investment options at any time. Participants can select from among these investment options for purposes of determining the earnings or losses that we will credit to their plan accounts, but they do not have an ownership interest in the investment options they select. Unlike our 401(k) Plan, we do not offer the opportunity for NDCP or SRP participants to invest through a brokerage window or in our Common Stock under our NDCP or SRP.Stock. The investment options in theavailable to NDCP and the SRP participants also differ from our 401(k) in that they include six target date portfolios based on different target retirement dates, referred to as “Target Retirement Portfolios,” that have been created for usewhich are used as default investment options.options (the “Target Retirement Portfolios”). The investment options available during 20192021 are described in the subsection “Investment Options Under the 401(k), Supplemental Retirement, Plan and Nonqualified Deferred Compensation Plan”Plans” below. Invested credits can be transferredreallocated among available plan investment options on any business day and effective at the close of business on that day (subject to the time of day the reallocation request andis made on a day the market beingis open).

 

Retirement and Savings Plan (401(k) Plan) and Supplemental Retirement Plan

 

Our 401(k) Plan is a qualified plan that is available to regular U.S.-based staff members of the Company and participating subsidiaries.subsidiaries (except Puerto Rico). All 401(k) Plan participants, including our NEOs, are eligible to receive the same proportionate level of matching and nonelective or “core” contributions from us. Company contributions on eligible compensation earned above the Internal Revenue Code qualified plan

compensation limit and on amounts that were deferred to the NDCP are credited to our SRP, a nonqualified plan that is available to all 401(k) Plan-eligible staff members.

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Executive Compensation Tables

Contributions. We make a core contribution of 5% of eligible compensation to all regular U.S.-based staff members under the 401(k) Plan, regardless of whether the staff members elect to defer any of their compensation to the 401(k) Plan. In addition, under the 401(k) Plan, participants are eligible to receive matching contributions of up to 5% of their eligible compensation that they contribute to the 401(k) Plan. Under our SRP, we credit 10% of each participant’s eligible compensation in excess of the maximum recognizable compensation limit for qualified plans, which equals the combined percentage of our core contributions and maximum matching contributions under our 401(k) Plan. We also credit to the SRP 10% of each participant’s compensation that is not eligible for deferral into our 401(k) Plan because the participant deferred itif they elect to defer to the NDCP.

Distributions. Participants receive distributions from the SRP following their termination of employment. Distributions for most participants are

made inParticipants may elect to receive distributions as a lump sum payment in the first or second year following termination of employment, or, for balances in excess of $100,000, in installments that commence in the year following termination. For our NEOs, Section 409A of the Internal Revenue Code generally requires that their distributions may not occur earlier than six months following our NEO’s termination of employment.

Participants in the 401(k) Plan are immediately vested in participant and matching contributions and related earnings and losses on such amounts. Participants in the 401(k) Plan who were hired before January 1, 2020 are also immediately vested in core contributions and related earnings and losses on such amounts. Participants in the 401(k) Plan who were hired on or after January 1, 2020 will only become 100% vested in core contributions and related earnings and losses on such amounts after three years of service. Participants in the SRP are immediately vested in matching contributions that are made by us with respect to amounts the participants deferred under the NDCP and related earnings and losses on such amounts, and are fully vested in the remainder of their accounts upon the earlier of: (i) three continuous years of their service to us; (ii) termination of their employment on or after their normal retirement date (as defined in the 401(k) Plan); (iii) their disability (as defined in the 401(k) Plan); (iv) their death; or (v) a change of control and termination of their employment as described below in “Potential Payments Upon Termination or Change of Control—Change of Control Severance Plan.”

 

 

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Executive Compensation Tables

Nonqualified Deferred Compensation Plan

 

Our NDCP allows participants to defer receipt of a portion of their eligible compensation to a future date, with an opportunity to earntax-deferred returns on the deferrals. Members of our Board of Directors, or Board, and our U.S.- and Puerto Rico-based staff members at the director level or above, who include our NEOs, are eligible to participate in this plan. Our NEOs may participate in this plan on the same basis as the other participants in the plan.

Contributions. Participants who are staff members may elect to defer up to a maximum of 50% of their eligible base salary, up to a maximum of 80% of their annual cash incentive award, and up to 80% of sales commissions.Non-employee members of our Board may defer all or a portion of their fees, including retainers and meeting fees. In addition, we may, in our sole discretion, contribute additional amounts to any participant’s account at any time, such as contributingsign-on bonuses to the accounts of newly-hired staff members or for retention purposes.

Distributions. Participants may elect to receive distributions as a lump sum or, for balances in excess of $100,000, in annual installments for up to ten years. For most participants, distributions commence in the

first or second year following the participant’s termination of employment. For our NEOs, Section 409A of the Internal Revenue Code generally requires that distributions may not occur earlier than six months following our NEO’s termination of employment. Participants mayIn 2021, participants could also elect to receive anin-service distribution of an elective deferral (called a short-term deferral) that is paid no earlier than three full years after the end of the plan year in which the deferral was made. Participants may also petition for a distribution due to an unforeseeable financial hardship.

Vesting. Participants are at all times 100% vested in the amounts that they elect to defer and related earnings and losses on such amounts. As part of his initial hire package, and to replace the forfeiture of certain pension benefits at his former employer, we contributed $1 million to Mr. Gordon’s NDCP account upon his hiring in 2018. This contribution and related earnings and losses thereon vestvested at the rate of 33%, 33%, and 34% per year on the anniversary of his hire date in 2019, 2020, and 2021, respectively, as long as Mr. Gordon remainsremained continuously employed by us, which vesting accelerates upon a change of control consistent with the terms of the NDCP. As part of his initial hire package, and to replace the forfeiture of certain pension benefits at his former employer, we contributed $1.6 million to Mr. Meline’s NDCP account upon his hiring in 2014. This contribution and related earnings and losses thereon vest at the rate of 12.5% per year from 2015 through 2022 as long as Mr. Meline remains continuously employed by us, which vesting accelerates upon a change of control consistent with the terms of the NDCP. As part of his initial hire package and to replace forfeiture of certain benefits at his former employer and to induce Mr. Graham to accept the Company’s offer of employment, Mr. Graham was provided with a contribution to his NDCP account of $2 million upon his hiring in 2015. This contribution and related earnings and losses thereon vest at the rate of 20% per year from 2016 through 2020 as long as Mr. Graham remains actively and continuously employed by us, which vesting accelerates upon death, disability, termination of employment not for cause, or a change of control consistent with the terms of the NDCP.us.

 

 

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Executive Compensation Tables

 

 

 

 

 

Investment Options Under the 401(k), Supplemental Retirement, Plan and Nonqualified Deferred Compensation PlanPlans

 

The investment options under the 401(k), the SRP, and the NDCP are substantially the same and their annualthe associated rates of return for 2019 are contained in the tables below. The 401(k) Plan offers the same investment options asFor the SRP and the NDCP except: (i)only, six target retirement portfolio options (referred to as “Target Retirement Portfolios” below) are among the 401(k) Plan also allows investments in our Common Stock (no more than 20%)deemed investment options and offers a brokerage window; and (ii) the 401(k) Plan does not offer the six portfoliosare based on different target retirement dates referred to as “Target Retirement Portfolios” below.

The Target Retirement Portfolios areand designed to provide anall-in-one investment option for creating a diversified portfolio. Each portfolio is an asset allocation strategy built around a combination of

investments from the plan’s investment options (provided below) andthat is adjusted over time to gradually become more conservative as the target maturity date of the portfolio approaches. We retain

For the right to change, at401(k) Plan only, participants may make investments in our discretion,Common Stock (no more than 20% of the value of a participant’s account) and access a self-directed brokerage window. Since they are available only under the 401(k) Plan, the performance of these additional investment options.options are not included in the following table.

 
  Name of Investment Option  

Rate of Return        

for 2019        

    

 

   Name of Investment Option    

Rate of Return    

for 2019    

 

Amgen Target Retirement Portfolio Income

  

 

17.28%

 

   

Large Cap Value

    

 

33.95%

 

Amgen Target Retirement Portfolio 2020

  

 

18.29%

 

   

Large Cap Index

    

 

31.49%

 

Amgen Target Retirement Portfolio 2030

  

 

20.92%

 

   

Large Cap Growth

    

 

32.52%

 

Amgen Target Retirement Portfolio 2040

  

 

25.36%

 

   

Small-Mid Cap Value

    

 

21.53%

 

Amgen Target Retirement Portfolio 2050

  

 

26.88%

 

   

Small-Mid Cap Index

    

 

27.86%

 

Amgen Target Retirement Portfolio 2060

  

 

26.62%

 

   

Small-Mid Cap Growth

    

 

33.35%

 

Capital Preservation

  

 

2.57%

 

   

International Value

    

 

21.95%

 

Fixed Income Index

  

 

8.69%

 

   

International Index

    

 

21.66%

 

Fixed Income

  

 

8.96%

 

   

International Growth

    

 

27.70%

 

High Yield

  

 

14.46%

 

   

Emerging Markets

    

 

20.38%

 

Inflation-Protection

  

 

8.42%

 

      

Real Estate Index

    

 

28.55%

 

  Name of Investment Option(1)

  

Rate of Return for    

2021    

      

Name of Investment Option(1)

    

Rate of Return for

2021

 

Target Retirement Portfolio Options(2)

     Capital Preservation     1.14

Target Retirement Portfolio Income

   7.57   Fixed Income Index     -1.63

Target Retirement Portfolio 2020

   7.93   Fixed Income Active     -1.04

Target Retirement Portfolio 2030

   9.95   International Equity Index     7.83

Target Retirement Portfolio 2040

   14.35   

International Equity Active

     11.25

Target Retirement Portfolio 2050

   16.50   

U.S. Equity Index

     25.61

Target Retirement Portfolio 2060

   16.23   

U.S. Equity Active

     19.02

(1)

We retain the right to change, at our discretion, the available investment options.

Potential Payments Upon Termination or Change of Control

 

Change of Control Severance Plan

 

Our Amended and Restated Change of Control Severance Plan, or Change of Control Severance Plan, provides a lump sum payment and certain other benefits for each participant in the plan who separates from employment with us in connection with a change of control. Our Compensation Committee periodically reviews the terms of the Change of Control Severance Plan, which was originally adopted in 1998, to ensure it is aligned with current governance best practices. No taxgross-up payments are provided under the Change of Control Severance Plan.

If a change of control occurs and a participant’s employment is terminated by us other than for cause or disability, or is terminated by the participant for good reason, within two years after the change of control, a participant under the Change of Control Severance Plan would be entitled to:

 

a lump sum cash payment in an amount equal to:

 

 - 

the product of:

 

a benefits multiple of one or two based on the participant’s position (each of our NEOs has a benefits multiple of two); and

 

the sum of (i) the participant’s annual base salary immediately prior to termination or, if higher, immediately prior to the change of control, plus (ii) the participant’s targeted annual cash incentive award for the year in which the termination occurs;

prior to the change of control, plus (ii) the participant’s targeted annual cash incentive award for the year in which the termination occurs;

if, as a result of the participant’s termination of employment, the participant becomes entitled to, and timely elects to continue, healthcare (including any applicable vision benefits) and/or dental coverage under Consolidated Omnibus Budget Reconciliation Act of 1985, or COBRA, Company-paid group health and dental insurance continuation coverage for the participant and his or her dependents under COBRA until the earlier of (i) the expiration of a participant’s eligibility for coverage under COBRA, or (ii) the expiration of the18-month period immediately following the participant’s termination (whichever occurs earlier);

 

fully-vested benefits accrued under our 401(k) Plan and our SRP;

 

either alump-sum cash payment or a contribution to our SRP, as determined by us in our sole discretion, in an amount equal to the sum of (1) the product of $2,500 and the participant’s benefits multiple, andplus (2) the product of (x) 10%, (y) the sum of (i) the participant’s annual base salary as in effect immediately prior to the participant’s termination or, if higher, as in effect immediately prior to the change of control, plus (ii) the participant’s targeted annual cash incentive award for the year in which the termination occurs (which equals the participant’s annual base salary multiplied by the participant’s target annual cash incentive award percentage, each as in effect immediately prior to the termination or, if higher, as in effect immediately prior to the change of control), and (z) the benefits multiple; and

 

 

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(which equals the participant’s annual base salary multiplied by the participant’s target annual cash incentive award percentage, each as in effect immediately prior to the termination or, if higher, as in effect immediately prior to the change of control), and (z) the benefits multiple; and

 

indemnification and, if applicable, directors’ and officers’ liability insurance provided by us for four years following the participant’s termination (each of our NEOs would receive such liability insurance benefits, which would result in no additional cost to us).

If all payments or benefits received under the Change of Control Severance Plan or any other plan, arrangement, or agreement would cause the participant to be subject to excise tax, then the payments will be reduced to the extent necessary to avoid the excise tax, provided that the reduced payments, net of federal, state, and local income taxes, are greater than the payments without such reduction, net of federal, state, and local income taxes, and excise tax.

The plan provides that the benefits described above would be provided in lieu of any other severance benefits that may be payable by us (other than accrued vacation and similar benefits otherwise payable to all staff members upon a termination). The plan also provides that the benefits described above may be forfeited if the participant discloses our confidential information or solicits or offers employment to any of our staff members during a period of years equal to the participant’s benefits multiple following the participant’s termination.

The plan is subject to automaticone-year extensions unless we notify participants no later than November 30 that the term will not be extended. If a change of control occurs during the term of the plan, the plan will continue in effect for at least 24 months following the change of control. Prior to a change of control, we can amend the plan at any time. After a change of control, the plan may not be terminated or amended in any way that adversely affects a participant’s interests under the plan, unless the participant consents in writing.

“Change “Change of Control” is defined in the plan as the occurrence of any of the following:

 

any person, entity, or group has acquired beneficial ownership of 50% or more of (i) our then outstanding common shares, or (ii) the combined voting power of our then outstanding securities entitled to vote in the election of directors;

individuals making up the incumbent Board (as defined in the plan) cease for any reason to constitute at least a majority of our Board;

 

immediately prior to our consummation of a reorganization, merger, or consolidation with respect to which persons who were the stockholders of the Company immediately prior to such transaction do not, immediately thereafter, own more than 50% of the then outstanding shares of the reorganized, merged, or consolidated company entitled to vote generally in the election of directors;

 

a liquidation or dissolution of the Company or the sale of all or substantially all of the assets of the Company; or

 

any other event which the incumbent Board (as defined in the plan), in its sole discretion, determines is a change of control.

“Cause” is defined in the plan as (i) conviction of a felony or (ii) engaging in conduct that constitutes willful gross neglect or willful gross misconduct in carrying out the participant’s duties, resulting in material economic harm to us, unless the participant believed in good faith that the conduct was in, or not contrary to, our best interests.

“Disability” under the plan is determined based on our long-term disability plan as is in effect immediately prior to a change of control.

“Good reason” is defined in the plan as (i) an adverse and material diminution of a participant’s authority, duties, or responsibilities, (ii) a material reduction in a participant’s base salary, (iii) an increase in a participant’s daily commute by more than 100 miles roundtrip, or (iv) any other action or inaction by the Company that constitutes a material breach of the agreement under which the participant provides services. In order to terminate with “good reason,” a participant must provide written notice to the Company of the existence of the condition within the required period, the Company must fail to remedy the condition within the required time period and the participant must then terminate employment within the required time period.

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Executive Compensation Tables

Long-Term Incentive Equity Awards

Stock Options and Restricted Stock Units

Our stock plans (or the related grant agreements approved for use under such stock plans) provide for accelerated vesting or continued vesting of unvested stock options and RSUs in the circumstances described below.

Double-Trigger Qualifying Termination in Connection with a Change of Control. Unvested stock options and RSUs will vest in full in connection with a Change of Control (as defined in the stock plans or related grant agreements approved for use under such stock plans) only if and when, within 24 months following the Change of Control, the grantee’s employment is involuntarily terminated other than for “cause” or “disability,” and,or, in the case of staff members subject to the Change of Control Severance Plan, voluntarily terminated with “good reason” (as each is defined in the grant agreements).

Death or Disability. In general, unvested stock options and RSUs granted in calendar years prior to the year death or disability occurs vest in full upon the occurrence of such event. For unvested stock options and RSUs granted in the calendar year death or disability occurs, apro-rata amount of these stock options and RSUs immediately vests based on the number of completed months of employment during the calendar year such event occurs. Under our stock plans, a disability has the same meaning as under Section 22(e)(3) of the Internal Revenue Code and occurs where the disability has been certified by either the Social Security Administration, the comparable government authority in another country with respect tonon-U.S. staff members, or an independent medical advisor appointed by us.

Retirement.In general, unvested stock options and RSUs granted in calendar years prior to the year in which an employee retires continue to vest on their original vesting schedule following the retirement of the holder if the holder has been continuously employed for at least ten

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Executive Compensation Tables

years and is age 55 or older or is age 65 or older, regardless of service (a retirement-eligible participant), provided that, beginning with RSUs granted in 2018, any unvested RSUs will vest in full in the event of death following such holders’ retirement from the Company. If a retirement-eligible participant receives a grant of stock options or RSUs in the calendar year such retirement occurs, generally, the participant will vest in apro-rata amount of the award he or she would be otherwise entitled based upon the number of complete months of employment during the calendar year such retirement occurs. Holders have the lesser of five years from the date of retirement or the remaining period before expiration to exercise any vested stock options. Mr. Bradway and Dr. Reese are eligible to receive this benefit because each has met the above-mentioned retirement requirements.

In March 2019 and 2020, the Compensation Committee approved retirement provisions for Mr. Meline’s LTI equity awards for 2019 and 2020 (composed of his annual performance unit, RSU, and stock option awards) by providing that, contingent upon Mr. Meline’s continued employment with the Company for at least five calendar years, retirement eligibility would be met for the 2019 and 2020 awards at age 62. Mr. Meline’s 2020 awards will bepro-rated based upon the number of complete months of employment in 2020. In making these determinations, the Compensation Committee took into consideration Mr. Meline’s lengthy tenure as a Chief Financial Officer of large public companies, the importance of retaining his expertise and experience, and his assistance in transitioning the Chief Financial Officer role. Accordingly, Mr. Meline is eligible to receive the benefits described above as to the stock options and RSUs granted to him in 2019 and 2020.

Performance Units

Performance units are generally forfeited unless a participant is continuously employed through the last business day of the performance period. The underlying principle is that the participant needs to have been an active employee during the entire performance

period in order to have contributed to the results on which the earned awards are based. Exceptions to this treatment are a termination of employment in connection with a change of control or the death, disability, or retirement of a participant.

Change of Control. Generally, with respect to grants of outstanding performance units, the performance period terminates as of the last business day of the last completed fiscal quarter preceding the change of control. The TSR market condition performance is based on: (A) our TSR performance for which our ending Common Stock price is computed on the greater of (i) the average daily closing price of our Common Stock for the last twenty (20) trading days of such shortened period, or (ii) the value of consideration paid for a share of our Common Stock in the change of control (whether such consideration is paid in cash, stock or other property, or any combination thereof); and (B) the TSR performance of the companies in the applicable reference group based on such companies’ average daily closing stock price for the last twenty (20) trading days of such shortened performance period. With respect to the operating performance measures, if the change of control occurs: (i) during the first fiscal year of the performance period,

target levels of performance shall be used to calculate the payment; and (ii) subsequent to the first fiscal year of the performance period, actual levels of performance for completed fiscal year(s) shall be used to calculate the payment. In the event of a change of control during the first six months of the performance period, however, the participant is entitled to a payment equal to an amount calculated in the manner described above, butpro-rated for the number of complete months elapsed during the shortened performance period. Change of control provisions for performance units granted to Mr. Gordon are the same as described above, except for design modifications to address Mr. Gordon’s hire date of September 3, 2018. If the change of control had occurred in 2019, Mr. Gordon would have received an amount based on target levels of performance (as reflected in the change of control table below). If the change of control occurs in 2020, he would receive an amount based on actual levels of performance for the first fully completed fiscal year.

Death or Disability. For all performance unit grants made in calendar years prior to the year death or disability occurs, the participant will be paid the full amount of the award he or she would be otherwise entitled to, if any, as determined at the end of the performance period. For a performance unit grant made in the calendar year in which death or disability occurs, a participant will be paid apro-rata amount of the award he or she would otherwise be entitled to, if any, as determined at the end of the performance period, based upon the number of complete months of employment in the calendar year such event occurs.

Retirement. In the event of retirement of a participant who is a retirement-eligible participant, for performance unit grants made in calendar years prior to the year in which retirement occurs, the participant will be paid the full amount of the award he or she would be otherwise entitled to, if any, as determined at the end of the performance period. If a retirement-eligible participant receives a performance unit grant in the calendar year such retirement occurs, the participant will be paid apro-rata amount of the award he or she would be otherwise entitled to, if any, as determined at the end of the performance period, based upon the number of complete months of employment during the calendar year such retirement occurs. Mr. Bradway and Dr. Reese are eligible to receive this benefit because each has met the above-mentioned retirement requirements.

In March 2019 and 2020, the Compensation Committee approved retirement provisions for Mr. Meline’s LTI equity awards for 2019 and 2020 (composed of annual performance unit, RSU, and stock option awards) by providing that, contingent upon Mr. Meline’s continued employment with the Company for at least five calendar years, retirement eligibility would be met for the 2019 and 2020 awards at age 62. Mr. Meline’s 2020 awards will bepro-rated based upon the number of complete months of employment in 2020. In making these determinations, the Compensation Committee took into consideration Mr. Meline’s lengthy tenure as a Chief Financial Officer of large public companies, the importance of retaining his expertise and experience, and his assistance in transitioning the Chief Financial Officer role. Accordingly, Mr. Meline is eligible to receive the benefits described above as to the 2019-2021 and 2020-2022 performance units.

 

 

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Executive Compensation Tables

 

 

 

 

 

Severance Terms in Mr. Gordon’sGriffith’s Offer Letter

We entered into an offer letter with Mr. GordonGriffith in connection with his initial hiring as Executive Vice President, Global Commercial Operations,Finance, effective September 3, 2018,October 23, 2019, which provides for limited severance benefits in the event of termination of employment by us, other than for “cause.” As discussed previously, we generally provide these terms in our offer letters with newly hired executive officers. Specifically, theMr. Griffith’s offer letter provides for cash severance protection for three years following his employment date equal to two year’s annual base salary and target annual cash incentive award, plus up to 18 months of COBRA medical and dental coverage paid for by us. Benefits of this type are provided to officer-level candidates to provide an incentive to them to join our Company by reducing the risk of making such a job change. TheseThe severance benefits for Mr. Griffith expire on September 3, 2021,October 23, 2022, and are payable only if Mr. GordonGriffith is terminated other than for “cause.” For purposes of the offer letter, “cause” is defined as: (i) unfitness for service, inattention to or neglect of duties, or incompetence; (ii) dishonesty; (iii) disregard or violation of the policies or procedures of the Company; (iv) refusal or failure to follow lawful directions of the Company; (v) illegal, unethical, or immoral conduct; or (vi) breach of our Proprietary Information and Inventions Agreement.

Estimated Potential Payments

The tables below set forth the estimated current value of payments and benefits: (i) to each of our NEOs upon a change of control, upon a qualifying termination within two years following a change of control, or

upon death or disability; (ii) to Messrs.Mr. Bradway and Meline and Dr. Reese upon retirement; and (iii) to Mr. Gordon,Griffith, upon termination without “cause.” All amounts shown in the tables below assume that the triggering events occurred on December 31, 20192021 and do not include: (i) the 2017-20192019-2021 performance unit awards and the 20192021 EIP payouts, which were earned as of December 31, 2019;2021; (ii) other benefits earned during the term of our NEO’s employment that are available to all salaried staff members, such as accrued vacation; (iii) benefits paid by insurance providers under life and disability policies; and (iv) benefits previously accrued and vested under the SRP and the NDCP. For information on the accrued amounts payable under these plans, see the “Nonqualified Deferred Compensation” table above. The actual amounts of payments and benefits that would be provided can only be determined at the time of a change of control and/or the NEO’s separation from the Company. In accordance with SEC rules, the value of accelerated equity awards shown in the tables below was calculated using the closing price of our Common Stock on December 31, 20192021 ($241.07)224.97). The amounts shown for accelerated stock options is the difference between the closing price at December 31, 20192021 ($241.07)224.97), and the exercise price of unvested stock options, multiplied by the number of unvested stock options. The value per unit of accelerated RSUs and performance units, including the related accrued dividend equivalents (rounded down to the nearest whole number of units), equals the applicable closing price multiplied by the number of units and dividend equivalents vested or earned, as applicable, as a result of such event.

 

 

Estimated Payments to Robert A. Bradway

 

 Triggering Event 
 Triggering Event 
Estimated Potential Payment or Benefit 

Change in

        Control($)

   

 

   

Change in

Control and

        Termination($)

           Retirement($)   

Death or

    Disability($)

  

Change in

Control($)

   

Change in

Control and

Termination($)

   Retirement($)   Death or
Disability($)
 

Lump sum cash severance payment

  0  

 

   8,000,000    0    0   0    8,364,000    0    0 

Intrinsic value of accelerated unvested stock options

  0  

 

   26,009,668    26,009,668    26,009,668   0    6,153,285    6,153,285    6,153,285 

Intrinsic value of accelerated unvested RSUs

  0  

 

   11,312,210    11,312,210    11,312,210   0    9,728,153    9,728,153    9,728,153 

Value of 2019-2021 performance units

  11,895,117(1)  

 

   11,895,117(1)    11,629,699(2)    11,629,699(2) 

Value of 2021-2023 performance units

  5,036,853(1)    5,036,853(1)    5,317,391(2)    5,317,391(2) 

Value of 2018-2020 performance units

  8,684,306(1)  

 

   8,684,306(1)    10,068,771(2)    10,068,771(2) 

Value of 2020-2022 performance units

  6,219,296(1)    6,219,296(1)    5,568,682(2)    5,568,682(2) 

Continuing health care benefits for 18 months(3)

  0  

 

   37,801    0    0   0    41,320    0    0 

Continuing retirement plan contributions for two years(4)

  0  

 

   805,000    0    0   0    841,400    0    0 
  

Total

  20,579,423   

 

   66,744,102    59,020,348    59,020,348   11,256,149    36,384,307    26,767,511    26,767,511 

 

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Executive Compensation Tables

Estimated Payments to Murdo Gordon

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   

Change in

Control and

Termination($)

   

Termination

Without

Cause($)(5)

   

Death or

Disability($)

 

Lump sum cash severance payment

  0    2,617,383(6)    4,100,000    0 

Intrinsic value of accelerated unvested stock options

  0    2,510,996    0    2,510,996 

Intrinsic value of accelerated unvested RSUs

  0    6,673,782    0    6,673,782 

Value of 2019-2021 performance units

  3,398,364(1)    3,398,364(1)    0    3,322,668(2) 

Value of 2018-2020 performance units

  3,800,227(1)    3,800,227(1)    0    5,007,988(2) 

Continuing health care benefits for 18 months(3)

  0    37,801    37,801    0 

Continuing retirement plan contributions for two years(4)

  0    415,000    0    0 

Acceleration of unvested balance of SRP account

  0    128,221    0    128,221 

Acceleration of unvested balance of DCP account

  747,606    747,606    747,606    747,606 
     

    Total

  7,946,197    20,329,380    4,885,407    18,391,261 

Estimated Payments to David W. Meline

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   

Change in

Control and

Termination($)

   Retirement($)(7)   

Death or

Disability($)

 

Lump sum cash severance payment

  0    3,993,600    0    0 

Intrinsic value of accelerated unvested stock options

  0    7,820,793    2,510,996    7,820,793 

Intrinsic value of accelerated unvested RSUs

  0    3,410,899    1,110,953    3,410,899 

Value of 2019-2021 performance units

  3,398,364(1)    3,398,364(1)    3,322,668    3,322,668(2) 

Value of 2018-2020 performance units

  2,778,814(1)    2,778,814(1)    0    3,221,901(2) 

Continuing health care benefits for 18 months(3)

  0    37,801    0    0 

Continuing retirement plan contributions for two years(4)

  0    404,360    0    0 

Acceleration of unvested balance of DCP account

  708,954(5)    708,954(5)    0    0 
     

    Total

  6,886,132    22,553,585    6,944,617    17,776,261 

Estimated Payments to David M. Reese

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   

Change in

Control and

Termination($)

   Retirement($)   

Death or

Disability($)

 

Lump sum cash severance payment

  0    1,849,912(6)    0    0 

Intrinsic value of accelerated unvested stock options

  0    3,716,727    3,716,727    3,716,727 

Intrinsic value of accelerated unvested RSUs

  0    5,698,172    1,632,940(8)    5,698,172 

Value of 2019-2021 performance units

  3,398,364(1)    3,398,364(1)    3,322,668(2)    3,322,668(2) 

Value of 2018-2021 performance units

  625,095(1)    625,095(1)    724,656(2)    724,656(2) 

Continuing health care benefits for 18 months(3)

  0    37,801    0    0 

Continuing retirement plan contributions for two years(4)

  0    394,520    0    0 
     

    Total

  4,023,459    15,720,591    9,396,991    13,462,223 

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Executive Compensation Tables

 

 

 

 

 

Estimated Payments to Jonathan P. GrahamMurdo Gordon

 

 Triggering Event  Triggering Event 
Estimated Potential Payment or Benefit 

Change in

Control($)

 

Change in

Control and

Termination($)

   

Death or

Disability($)

  

Change in

Control($)

   Change in
Control and
Termination($)
   Retirement($)   Death or
Disability($)
 

Lump sum cash severance payment

  0   3,834,000    0   0    4,287,200    0    0 

Intrinsic value of accelerated unvested stock options

  0   5,456,204    5,456,204   0    1,257,557    0    1,257,557 

Intrinsic value of accelerated unvested RSUs

  0   4,606,607    4,606,607 

Intrinsic value of accelerated unvested RSU’s

  0    2,519,889    0    2,519,889 

Value of 2019-2021 performance units

  2,378,638(1)   2,378,638(1)    2,325,602(2) 

Value of 2021-2023 performance units

  1,582,439(1)    1,582,439(1)    0    1,670,627(2) 

Value of 2018-2020 performance units

  1,945,194(1)   1,945,194(1)    2,255,451(2) 

Value of 2020-2022 performance units

  1,770,514(1)    1,770,514(1)    0    1,585,364(2) 

Continuing health care benefits for 18 months(3)

  0   37,801    0   0    41,320    0    0 

Continuing retirement plan contributions for two years(4)

  0   388,400    0   0    433,720    0    0 
 

Acceleration of unvested balance of DCP account

  562,280   562,280    562,280 
 

Total

  4,886,112   19,209,124    15,206,144   3,352,953    11,892,639    0    7,033,437 

Estimated Payments to David M. Reese

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   Change in
Control and
Termination($)
   Retirement($)   Death or
Disability($)
 

Lump sum cash severance payment

  0    4,280,000    0    0 

Intrinsic value of accelerated unvested stock options

  0    1,383,696    1,383,696    1,383,696 

Intrinsic value of accelerated unvested RSU’s

  0    3,648,114    2,567,976(5)    3,648,114 

Value of 2021-2023 performance units

  1,519,222(1)    1,519,222(1)    1,603,811(2)    1,603,811(2) 

Value of 2020-2022 performance units

  1,770,514(1)    1,770,514(1)    1,585,364(2)    1,585,364(2) 

Continuing health care benefits for 18 months(3)

  0    41,320    0    0 

Continuing retirement plan contributions for two years(4)

  0    433,000    0    0 
     

    Total

  3,289,736    13,075,866    7,140,847    8,220,985 

Estimated Payments to Peter H. Griffith

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   

Change in

Control and

Termination($)

   Termination
Without
Cause($)
(6)
   Death or
Disability($)
 

Lump sum cash severance payment

  0    4,056,800    4,056,800    0 

Intrinsic value of accelerated unvested stock options

  0    0    0    0 

Intrinsic value of accelerated unvested RSU’s

  0    4,524,372    0    4,524,372 

Value of 2021-2023 performance units

  1,265,906(1)    1,265,906(1)    0    1,336,322(2) 

Value of 2020-2022 performance units

  1,727,320(1)    1,727,320(1)    0    1,546,669(2) 

Continuing health care benefits for 18 months(3)

  0    41,320    41,320    0 

Continuing retirement plan contributions for two years(4)

  0    410,680    0    0 

Acceleration of unvested balance of SRP

  0    132,273    0    132,273 
     

    Total

  2,993,226    12,158,671    4,098,120    7,539,636 

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Executive Compensation Tables

Estimated Payments to Esteban Santos

  Triggering Event 
  Estimated Potential Payment or Benefit 

Change in

Control($)

   Change in
Control and
Termination($)
   Retirement($)   Death or
Disability($)
 

Lump sum cash severance payment

  0    3,974,000    0    0 

Intrinsic value of accelerated unvested stock options

  0    1,492,807    0    1,492,807 

Intrinsic value of accelerated unvested RSU’s

  0    2,628,999    0    2,628,999 

Value of 2021-2023 performance units

  1,503,475(1)    1,503,475(1)    0    1,587,163(2) 

Value of 2020-2022 performance units

  1,727,320(1)    1,727,320(1)    0    1,546,669(2) 

Continuing health care benefits for18 months(3)

  0    45,800    0    0 

Continuing retirement plan contributions for two years(4)

  0    402,400    0    0 
     

    Total

  3,230,795    11,774,801    0    7,255,638 

 

(1) 

In the event of a change of control occurring(with or without a qualifying termination) that occurs after the first six months of the 2019-20212021-2023 performance period, the number of performance units that would have been earned is the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2019,2021, multiplied by a payout percentage of 130%70%, which employs the plan dictated target level of performance for the operating performance measures of 100% modified updown by 30 percentage points by the TSR modifier which is based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 3, 2019April 30, 2021 grant date through September 30, 2019,2021, the last business day of the last fiscal quarter before the change in control.

In the event of a change of control occurring (with or without a qualifying termination) that occurs during the second year of the 2020-2022 performance period, the number of performance units that would have been earned is the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2021, multiplied by a payout percentage of 90.8%, which is the percentage based on the estimated outcomes of our operating performance measures achieved during the first year of the performance period of 120.8%, decreased by the TSR modifier by 30 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 5, 2020 grant date to September 30, 2021, the last business day of the last fiscal quarter before the change in control.

In the event of a change of control occurring during the second year of the 2018-2020 performance period, the number of performance units that would have been earned, except for Mr. Gordon, is the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2019, multiplied by a payout percentage of 103.5%, which is the percentage based on the estimated outcomes of our operating performance measures achieved during the first year of the performance period of 89.4%, increased by the TSR modifier by 14.1 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the April 27, 2018 grant date to September 30, 2019, the last business day of the last fiscal quarter before the change in control. With respect to Mr. Gordon, because of his late start date in 2018, the number of performance units that would have been earned for the first full fiscal year of the 2018-2020 performance period of 85.9% is based on a target level of performance for the operating measures of 100%, decreased by the TSR modifier by 14.1% percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the November 2, 2018 grant date to September 30, 2019,

Our TSRs for purposes of determining the payout percentages of these awards would be based on the higher of: (i) the average closing price of our Common Stock for the last 20 trading days of the shortened performance period ended on September 30, 2021; and (ii) the value of consideration the acquirer paid for a share of our Common Stock in the change of control. For purposes of the payout values shown in the tables, the TSRs for our Common Stock were based on the respective actual TSRs over the respective averaging periods ending September 30, 2021, the last business day of the last fiscal quarter before the change in control. The resulting number of units that would have been so earned was multiplied by $224.97, the closing price of our Common Stock on December 31, 2021.

For information on the actual number of units to be earned for these performance unit grants, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis.

Our TSRs for purposes of determining the payout percentages of these awards would be based on the higher of: (i) the average closing price of our Common Stock for the last 20 trading days of the shortened performance period ended on September 30, 2019; and (ii) the value of consideration the acquirer paid for a share of our Common Stock in the change of control. For purposes of the payout values shown in the tables, the TSRs for our Common Stock were based on the respective actual TSRs over the respective averaging periods ending September 30, 2019, the last business day of the last fiscal quarter before the change in control. The resulting number of units that would have been so earned was multiplied by $241.07, the closing price of our Common Stock on December 31, 2019.

For information on the actual number of units to be earned for these performance unit grants, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis.

(2)

In the event death or disability occurs, the participant is entitled to the number of performance units that would have been earned by the NEO if he had remained employed for the entire performance period. For purposes of the payout values shown in the tables, the number of units that would have been earned was multiplied by $241.07,$224.97, the closing price of our Common Stock on December 31, 2019.

For the 2019-2021 performance period, the number of performance units that would have been earned is the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2019, multiplied by the payout percentage of 127.1%. The payout percentage is based on the estimated outcomes as of December 31, 2019, of our operating performance measures to be achieved during the performance period of 97.1%, which was increased by the TSR modifier by 30 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 3, 2019 grant date to December 31, 2019.2021.

For the 2021-2023 performance period, the number of performance units that would have been earned has been estimated as the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2021, multiplied by the payout percentage of 73.9%. The payout percentage is based on the estimated outcomes as of December 31, 2021, of our operating performance measures to be achieved during the performance period of 103.9%, which was decreased by the TSR modifier by 30 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the April 30, 2021 grant date to December 31, 2021.

For the 2018-2020 performance period, the number of performance units that would have been earned, except for Mr. Gordon, is the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2019, multiplied by the payout percentage of 120.0%. The payout percentage is based on the estimated outcomes as of December 31, 2019, of our operating performance measures to be achieved during the performance period of 90.0%, which was increased by the TSR modifier by 30 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the April 27, 2018 grant date to December 31, 2019. With respect to Mr. Gordon’s grant of performance units for the 2018-2020 performance period, the number of performance units that would have been earned in the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2019, multiplied by the payout percentage of 113.2%. The payout percentage is based on estimated outcomes as of December 31, 2019, of our operating measures to be achieved during the performance period of 90.3% which was increased by the TSR modifier by 22.9 percentage points from the November 2, 2018 grate date to December 31, 2019.

For the 2020-2022 performance period, the number of performance units that would have been earned has been estimated as the sum of the number of performance units granted and related dividend equivalents accrued through December 31, 2021, multiplied by the payout percentage of 81.3%. The payout percentage is based on the estimated outcomes as of December 31, 2021, of our operating performance measures to be achieved during the performance period of 111.3%, which was decreased by the TSR modifier by 30 percentage points based on our TSR percentile rank relative to the TSRs of the companies in the Reference Group for the period from the May 5, 2020 grant date to December 31, 2021.

In the event of actual death or disability, payout of shares in satisfaction of amounts earned for grants for the 2019-2021 and 2018-2020 performance periods would not occur until after the end of the performance periods. For more information, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis.

In the event of actual death or disability, payout of shares in satisfaction of amounts earned for grants for the 2021-2023 and 2020-2022 performance periods would not occur until after the end of the performance periods and would be based on actual performance through the end of the performance period. For more information, see “Elements of Compensation and Specific Compensation Decisions—Long-Term Incentive Equity Awards” in our Compensation Discussion and Analysis.

As Mr. Bradway and Dr. Reese were retirement-eligible as of December 31, 2019, the retirement payout amounts for performance units for the 2019-2021 and 2018-2020

As Mr. Bradway and Dr. Reese were retirement-eligible as of December 31, 2021, the retirement payout amounts for performance units for the 2021-2023 and 2020-2022 performance periods were calculated in the same manner as the respective death and disability amounts.

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Executive Compensation Tables

(3) 

Reflects the estimated cost of medical, dental, and vision insurance coverage based on rates charged to our staff members for post-employment coverage provided in accordance with COBRA for the first 18 months following termination adjusted for the last six months of this period by ana 5% inflation factor for medical coverage and a 6%3% inflation factor for dental coverage.

(4) 

Reflects the value of retirement plan contributions for two years calculated as two times the sum of: (i) $2,500; and (ii) the product of: (a) 10%; and (b) the sum of the NEO’s annual base salary as of December 31, 2019,2021, and the NEO’s targeted annual cash incentive award for 20192021 (which equals the NEO’s annual base salary as of December 31, 2019,2021, multiplied by the NEO’s target annual cash incentive award percentage for 2019)2021).

(5)

Excludes the value of unvested RSUs (including related accrued dividend equivalents rounded down to the nearest whole number of units) granted to Dr. Reese on November 2, 2018 in connection with his promotion, totaling 4,801 units which do not provide for continued vesting after retirement.

(6) 

Reflects amounts that would be paid to Mr. GordonGriffith pursuant to his offer letter in the event Mr. GordonGriffith was terminated without “cause,” including two years of annual salary and annual target incentive bonus, as defined, and the cost of providing continuing medical and dental insurance coverage for 18 months in accordance with COBRA calculated in the same manner as described in footnote 3 above. The terms of Mr. Gordon’sGriffith’s offer letter relating to these benefits expire at the end of the third year of his employment on September 3, 2021.

(6)

Reflects the cash severance payment pursuant to our Change of Control Severance Plan described above. The payment to Mr. Gordon and Dr. Reese were reduced by $1,482,617 and $2,045,288, respectively, from the amounts otherwise due to them to avoid excise tax they would be liable for if all benefits pursuant to the Change of Control Severance Plan were paid to Mr. Gordon and Dr. Reese. For purposes of determining whether the cash severance payment reduction should be made, we applied the highest applicable federal and state income tax rates to the benefits subject to income taxes that would be payable to Mr. Gordon and Dr. Reese pursuant to the Change of Control Severance Plan in the tables above.

(7)

Reflects the value of stock options, RSUs and performance units for the 2019-2021 performance period granted to Mr. Meline in 2019 in which retirement eligibility was met at age 62. The retirement payout amount for performance units for the 2019-2021 performance period was calculated in the same manner as the death and disability amount.

(8)

Excludes the value of unvested RSUs (including related accrued dividend equivalents rounded down to the nearest whole number of units) granted to Dr. Reese on May 1, 2017 and November 2, 2018, totaling 16,864 units which do not provide for continued vesting after retirement.October 23, 2022.

 

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Director Compensation

 

 

 

 

 

Director Compensation

 

The compensation program for ournon-employee directors is intended to be competitive and fair so that we can attract the best talent to our Board of Directors, or Board, and recognize the time and effort required of a director given the size and complexity of our operations. In addition to cash compensation, we provide equity grants and have stock

ownership guidelines to align the directors’ interests with all of our stockholders’ interests and to motivate our directors to focus on our long-term growth and success. Directors who are our employees are not paid any fees for serving on our Board or for attending Board meetings. In October 2017, the Governance and Nominating

Committee, or Governance Committee, reviewed our director compensation. The Governance Committee hired Frederic W. Cook & Co., Inc., or FW Cook, as an independent consultant to the Governance Committee to advise on director compensation. FW Cook provided detailed competitive comparisons against our peer group and recommended no changes to our director compensation levels. Based on this review and recommendation by FW Cook, the Governance Committee recommended to the Board that no changes be made to the compensation levels for directors.

 

 

20192021 Director Compensation

 

 

  Position  

Annual Cash
Retainer

($)

   

Annual Equity Awards  
(Restricted Stock Units  
Grant Date Market Value)  

($)  

 

  Non-Employee Director

   105,000    210,000   

  Lead Independent Director Retainer

   40,000    —   

  Committee Chair Retainers

     —   

  Audit Committee Chair

     30,000    —   

  Other Committee Chairs (Compensation and Management Development, Corporate Responsibility and Compliance, and Governance and Nominating Committees)

     20,000    —   

  Committee Member Meeting Retainer

      12,500    —   

Cash Compensation.Equity Incentives. Eachnon-employee director receivesreceived an automatic annual grant of restricted stock units, or RSUs, on the date of the annual meeting of stockholders, with a grant date fair market value of $210,000, based on the closing price of our Common Stock on the grant date (rounded down to the nearest whole number). The RSUs vest immediately, and to further support long-term holding, a director may choose to defer receipt of such shares. Directors who elect to defer receipt of the shares accrue dividend equivalents on the vested RSUs during the deferral period. Further, to increase their equity holdings, a director may also elect to receive deferred vested RSUs in lieu of up to 100% of his or her cash compensation.

Director Stock Ownership Guidelines. All non-employee directors are expected to hold the equivalent of five times the Board annual cash retainer of $100,000. In addition, chairs($525,000 in 2021) in our Common Stock while serving as a non-employee director.

All non-employee directors are expected to comply with the stock ownership guidelines on or before December 31st of the four key standing committees receive an additional $20,000 annual retainer as follows: (i) Audit Committee; (ii) Compensation and Management Development Committee; (iii) Corporate Responsibility and Compliance Committee; and (iv) Governance and Nominating Committee. The lead independent director receives an additional $35,000 annual retainer. Directors are not additionally compensated for Board meeting attendance. Directors are compensated $2,000 for each committee meeting they attend ($1,000 for telephonic attendance). Directors also may be compensated for attending meetingscalendar year in which the fifth anniversary of committeestheir first date of which they are not members or special meetings if they are invited to attendelection by the Chairmanstockholders falls. For purposes of the Board stock ownership guidelines, issued and outstanding shares of our Common Stock held beneficially or of record by the committee chair.non-employee director, issued and outstanding shares of our Common Stock held in a qualifying trust (as defined in the guidelines), and vested RSUs that are deferred will count towards satisfying these stock ownership guidelines. All directors with

compliance dates that were on or prior to December 31, 2021, met the stock ownership guidelines as of that date.

Board members are subject to our insider trading policy that, among other things, prohibits engaging in short sales with respect to the Company’s securities, purchasing or pledging the Company’s stock on margin(1), or entering into any hedging, derivative or similar transactions with respect to the Company’s securities.

Expenses. Directors are entitled to reimbursement of their expenses incurred in connection with attendance at Board and committee meetings and conferences with our senior management.Senior Management. We make taxgross-up payments to our directors to reimburse them for additional income taxes imposed when we are required to impute income on perquisites that we provide.

Equity Incentives. Under the provisionsGuests of our revised Director Equity Incentive Program, eachnon-employee director receives an automatic annual grant of restricted stock units,Board members are occasionally invited to Board events, and we may pay or RSUs,reimburse travel expenses and may provide transportation on the third business day after the release of our first fiscal quarter earnings, with a grant date fair market value of $200,000, based on the closing price of our Common Stock on the grant date (rounded down to the nearest whole number). The RSUs vest immediately, andaircraft for both the director may choose to defer receipt of the shares. Directors that elect to defer receipt of the shares accrue dividend equivalents on the vested RSUs during the deferral period. A director may also elect to receive deferred fully vested RSUs in lieu of up to 100% ofand his or her cash compensation.guest.

Deferred Compensation and Other Benefits.Compensation. Non-employee directors are eligible to participate in the Nonqualified Deferred Compensation Plan or NDCP, that we maintain for our staff members (see “Nonqualified Deferred Compensation” in our Executive Compensation Tables above for more information). Earnings under this plan are market-based—there are no “above market” or guaranteed rates of returns.

Through The Amgen Foundation, Inc., the Company maintains a charitable contributions matching gift program for all eligible staff members andnon-employee directors. Our directors participate in the program on the same terms as our staff members. The Amgen Foundation, Inc. matches, on adollar-for-dollar basis, qualifying donations made by directors and staff members to eligible organizations, up to $20,000 per person, per year. Separate and in addition to this ongoing annual program, The Amgen Foundation, Inc. matches, on adollar-for-dollar basis, donations to specified disaster relief organizations, up to $20,000 per deployment per person.

Guests of our Board members are occasionally invited to Board events, and we may pay or reimburse travel expenses and may provide transportation on our aircraft for both the director and his or her guest.

Director Stock Ownership Guidelines. Allnon-employee directors are expected to hold the equivalent of five times the Board annual cash retainer (currently $500,000) in our Common Stock while serving as anon-employee director.

Allnon-employee directors are expected to comply with the stock ownership guidelines on or before December 31st of the calendar year in which the fifth anniversary of their first date of election by stockholders or the Board falls. For purposes of the Board stock ownership guidelines, issued and outstanding shares of our Common Stock held beneficially or of record by thenon-employee director, issued and outstanding shares of our Common Stock held in a qualifying trust (as defined in the guidelines), and vested RSUs that are deferred will count towards satisfying the stock ownership guidelines. All directors with compliance dates that were on or prior to December 31, 2019, met the stock ownership guidelines as of that date.

Board members are subject to our insider trading policy that prohibits them from engaging in short sales with respect to the Company’s securities, purchasing or pledging the Company’s stock on margin, or entering into any hedging, derivative or similar transactions with respect to the Company’s securities.

 

 

(1)

With the exception of the use of a margin account to purchase our common stock in connection with the exercise of Amgen-granted stock options (i.e., “cashless exercises”).

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Director Compensation

 

 

 

 

 

Charitable Contributions. Through The Amgen Foundation, Inc., the Company maintains a charitable contributions matching gift program for all eligible staff members and non-employee directors. Our directors participate in the program on the same terms as our staff members. The Amgen Foundation, Inc. matches, on a dollar-for-dollar basis, qualifying donations made by directors and staff members to eligible

organizations, up to $20,000 per person, per year. Separate from, and in addition to, this ongoing annual program, in response to specific disasters (such as COVID-19 and the Australian wildfires), The Amgen Foundation, Inc. matches, on a dollar-for-dollar basis, donations to specified disaster relief organizations, up to $20,000 per deployment per person.

Director Compensation Table

 

The following table shows compensation of thenon-employee members of our Board for 2019.2021. Robert A. Bradway, our Chairman of the Board, Chief Executive Officer and President is not included in the table as he is an employee and thus receives no compensation for his service as a director.

 

Non-Employee Director

  

Fees Earned or
Paid in Cash($)
(4)

   

Stock

    Awards($)(5)(6)

   

All Other

    Compensation($)(7)

   

    Total($)

   Fees Earned or
Paid in Cash($)
(3)
   Stock
Awards($)
(4)(5)
   All Other
Compensation($)
(6)
   Total($) 

Wanda M. Austin

  

 

127,000

 

  

 

199,828

 

  

 

20,702

 

  

 

347,350

 

   130,000    209,970    20,000    359,970 

Brian J. Druker

  

 

125,000

 

  

 

199,828

 

  

 

20,327

 

  

 

345,155

 

   130,000    209,970    20,000    359,970 

Robert A. Eckert

  

 

176,000

 

  

 

199,828

 

  

 

20,702

 

  

 

396,530

 

   190,000    209,970    20,000    419,970 

Greg C. Garland

  

 

141,000

 

  

 

199,828

 

  

 

20,286

 

  

 

361,114

 

   150,000    209,970    20,000    379,970 

Fred Hassan(1)

  

 

126,000

 

  

 

199,828

 

  

 

17,786

 

  

 

343,614

 

   65,000    0    35,306    100,306 

Rebecca M. Henderson

  

 

118,000

 

  

 

199,828

 

  

 

32,135

 

  

 

349,963

 

Charles M. Holley, Jr.(2)

   0    369,970    0    369,970 

Frank C. Herringer(1)(2)

  

 

61,000

 

  

 

199,828

 

  

 

98,095

 

  

 

358,923

 

Charles M. Holley, Jr.(3)

  

 

72,691

 

  

 

271,377

 

  

 

12,753

 

  

 

356,821

 

S. Omar Ishrak(1)

   65,000    174,914    1,019    240,933 

Tyler Jacks

  

 

119,000

 

  

 

199,828

 

  

 

20,286

 

  

 

339,114

 

   130,000    209,970    0    339,970 

Ellen J. Kullman(3)

  

 

700

 

  

 

317,520

 

  

 

20,299

 

  

 

338,519

 

Ellen J. Kullman(2)

   0    339,970    20,023    359,993 

Amy E. Miles

   130,000    209,970    20,000    359,970 

Ronald D. Sugar

  

 

138,000

 

  

 

199,828

 

  

 

20,286

 

  

 

358,114

 

   150,000    209,970    20,000    379,970 

R. Sanders Williams

  

 

118,000

 

  

 

199,828

 

  

 

21,888

 

  

 

339,716

 

   130,000    209,970    20,165    360,135 

 

(1)

Mr. HerringerHassan retired from our Board in May 2019.2021 and Dr. Ishrak joined our Board in July 2021. Accordingly, fees earned by Mr. Herringer in 2019 consist of apro-rata amount of the annual retainer fee(pro-rated on a monthly basis) and feesbasis for committee meetings attendedactual service) in 2019.2021.

(2) 

All cash fees for Mr. Herringer were deferred under our NDCP.

(3)

Mr. Holley and Ms. Kullman elected to receive 50% and 100%, respectively, of their respective annual retainer and committee meeting fees in the form of deferred vested RSUs, the value of which are reflected in the stock awards column in accordance with Accounting Standards Codification Topic 718.

(4)(3)

Reflects all fees earned by members of our Board for participation in regular, telephonic, and special meetings of Board committees and annual retainers, as applicable. This column includes cash paid in lieu of issuing fractional shares of deferred RSUs.retainers.

(5)(4) 

Reflects the grant date fair values of RSUs determined in accordance with Accounting Standards Codification Topic 718 consisting of 1,127837 RSUs granted on May 3, 2019,18, 2021, to each director named above.above, except Mr. Hassan and Dr. Ishrak. Dr. Ishrak was granted 760 RSUs on August 6, 2021, which reflects a proration of the annual grant for service on the Board through the 2022 Annual Meeting of Stockholders. The grant date fair values of all of the annual awards are based on the closing price of our Common Stock on the grant date of $177.31,($250.86 and $230.15 on May 18 and August 6, 2021, respectively) multiplied by the number of RSUs granted. Such grants occuroccurred on the date of our annual meeting of stockholders or the third business day after release of our annual orapplicable quarterly earnings, as applicable.respectively. Directors thatwho elect to defer receipt of the shares accrue dividend equivalents on the vested RSUs during the deferral period. All of the RSUs granted to directors were fully vested upon grant.

In addition to the annual grants discussed above, Mr. Holley and Ms. Kullman were granted RSUs in lieu of cash fees earned in 2021 for 50% and 100%, respectively, of their annual retainer and committee meeting fees (rounded down to the nearest whole number of units) as follows:

 

  

Granted on

   Granted on (but receipt deferred) 

Non-Employee Director

  

May 3, 2019

   

    August 2, 2019

   

    November 1, 2019

   

    February 4, 2020

   April 30, 2021   August 6, 2021   November 5, 2021   

Charles M. Holley, Jr.

  

 

101

 

  

 

93

 

  

 

153

 

  

 

13

 

Charles M. Holley

   166    347    187  

Ellen J. Kullman

  

 

174

 

  

 

160

 

  

 

261

 

  

 

N/A

 

   135    282    152  

 

  

The grant date fair values per unit for these awards were $177.31, $187.22, $217.95$239.64, $230.15, and $221.81$213.77 for May 3, 2019,April 30, 2021, August 2, 2019,6, 2021, and November 1, 2019, and February 4, 2020,5, 2021, respectively.

 

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Director Compensation

 

 

 

 

 

(6)(5) 

Directors may elect to defer issuance of shares until a later date, which would result in a deferral of taxable income to the director until the lapse of such deferral. Upon the lapse of any applicable deferral period, the vested/deferred RSUs are paid in shares of our Common Stock on a one-for-one basis. Stock option awards consist of fully vested stock options. The table below shows the aggregate number of deferred stock awards (deferred RSUs and dividend equivalents) and stock option awards outstanding for eachnon-employee director as of December 31, 2019.2021. Deferred stock awards consist of vested RSUs for which receipt of the underlying shares of our Common Stock has been deferred (vested/deferred RSUs) and dividends on vested/deferred RSUs are deemed automatically reinvested to acquire additional vested/deferred RSUs (rounded down to the nearest whole number of units). Directors may elect to defer issuance of shares until a later date, which would result in a deferral of taxable income to the director until the stock issuance date. Upon the passage of any applicable deferral period, the vested/deferred RSUs are paid in shares of our Common Stock on aone-for-one basis. Stock option awards consist of fully exercisable stock options.RSUs.

 

Non-Employee Director  Deferred Restricted Stock Units and
Dividend Equivalents
as of December 31, 2019
(a)
   

Stock Option Awards  

Outstanding as of December 31, 2019(b)  

   Deferred Restricted Stock Units and
Dividend  Equivalents
as of December 31, 2021
(a)
   Stock Option Awards  
Outstanding as of  December 31, 2021
(b)  
 

Wanda M. Austin

  

 

0

 

  

 

0  

 

   0    0   

Brian J. Druker

  

 

1,859

 

  

 

0  

 

   3,714    0   

Robert A. Eckert

  

 

10,669

 

  

 

20,000  

 

   13,064    20,000   

Greg C. Garland

  

 

0

 

  

 

0  

 

   0    0   

Fred Hassan

  

 

0

 

  

 

0  

 

   0    0   

Rebecca M. Henderson

  

 

13,750

 

  

 

5,000  

 

Charles M. Holley, Jr.

   5,750    0   

Frank C. Herringer

  

 

25,491

 

  

 

10,000  

 

Charles M. Holley, Jr.

  

 

3,092

 

  

 

0  

 

S. Omar Ishrak

   0    0   

Tyler Jacks

  

 

8,501

 

  

 

0  

 

   9,913    0   

Ellen J. Kullman

  

 

4,955

 

  

 

0  

 

   8,134    0   

Amy E. Miles

   850    0   

Ronald D. Sugar

  

 

14,526

 

  

 

10,000  

 

   17,157    0   

R. Sanders Williams

  

 

0

 

  

 

0  

 

   0    0   

 

 (a) 

Restricted stock units and related dividend equivalents are all vested, but receipt has been deferred. Restricted stock units and related dividend equivalents earned on these amounts are rounded down to the nearest whole number of shares. Fractional shares are paid in cash.

 
 (b) 

All stock options are vested.

 

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Director Compensation

(7)(6)

The table below provides a summary of amounts paid by the Company for perquisites and other special benefits.

 

Non-Employee

Director

 

Matching of

Charitable

Contributions

($)(a)

 

  Personal Use of
Company
Aircraft
(b)

 

 

 

Expenses in
Connection
with Directors
on Business
Travel
(c)

 

 Other(d)

 

  

Dividends
Accrued on
Vested/
Deferred
RSUs($)
(e)

 

 

Total($)  

 

  

Matching of

Charitable

Contributions

($)(a)

  Personal Use of
Aircraft
(b)
  Personal Expenses
While on Business
Travel
(C)
  Other(d)  Total($)   

 

Aggregate

Incremental

Amounts($)

 

 

 

Tax

Gross-

Up($)

 

 

 

Aggregate

Incremental

Amounts($)

 

 

 

Tax

Gross-

Up($)

 

 

 

Aggregate

Incremental

Amounts($)

 

 

 

Tax

Gross-

Up($)

 

 

Aggregate

Incremental

Amounts($)

   

Tax

Gross-

Up($)

  

Aggregate

Incremental

Amounts($)

   

Tax

Gross-

Up($)

  

Aggregate

Incremental

Amounts($)

   

Tax

Gross-

Up($)

 

Wanda M. Austin

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

297

 

 

 

119

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,702  

 

  20,000   0    0   0    0   0    0   20,000   

Brian J. Druker

 

 

20,000

 

 

 

0

 

 

 

41

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,327  

 

  20,000   0    0   0    0   0    0   20,000   

Robert A. Eckert

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

297

 

 

 

119

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,702  

 

  20,000   0    0   0    0   0    0   20,000   

Greg C. Garland

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,286  

 

  20,000   0    0   0    0   0    0   20,000   

Fred Hassan

 

 

17,500

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

17,786  

 

  20,000   0    0   0    0   15,239    67   35,306   

Rebecca M. Henderson

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

11,849

 

 

 

32,135  

 

Charles M. Holley, Jr.

  0   0    0   0    0   0    0   0   

Frank C. Herringer

 

 

20,000

 

 

 

217

 

 

 

129

 

 

 

1,122

 

 

 

449

 

 

 

10,069

 

 

 

3,803

 

 

 

62,306

 

 

 

98,095  

 

Charles M. Holley, Jr.

 

 

10,000

 

 

 

345

 

 

 

604

 

 

 

1,184

 

 

 

334

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

12,753  

 

S. Omar Ishrak

  0   390    505   0    124   0    0   1,019   

Tyler Jacks

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,286  

 

  0   0    0   0    0   0    0   0   

Ellen J. Kullman

 

 

20,000

 

 

 

0

 

 

 

13

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,299  

 

  20,000   0    0   0    23   0    0   20,023   

Amy E. Miles

  20,000   0    0   0    0   0    0   20,000   

Ronald D. Sugar

 

 

20,000

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

0

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

20,286  

 

  20,000   0    0   0    0   0    0   20,000   

R. Sanders Williams

 

 

20,000

 

 

 

1,031

 

 

 

0

 

 

 

242

 

 

 

329

 

 

 

286

 

 

 

0

 

 

 

0

 

 

 

21,888  

 

  20,000   0    0   0    165   0    0   20,165   

 

 (a) 

These are charitable contributions of The Amgen Foundation, Inc. that matched the directors’ charitable contributions made in 2019.2021.

 
 (b) 

Where we have guests accompany directors on our aircraft or where the director, fornon-business nonbusiness purposes, accompanies executives using our aircraft for business purposes, we typically incur de minimis incremental costcosts for transporting that person, but we are required to impute income to the director for his or her income tax purposes. We reimburse the director for the additional income taxes imposed on the director in these circumstances. The aggregate incremental cost of use of our aircraft is calculated based on our variable operating costs, which include crew travel expenses,on-board catering, landing fees, trip-related hangar/parking costs, fuel, maintenance, and other smaller variable costs. In determining the incremental cost relating to fuel and trip-relatedtrip-

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Director Compensation

related maintenance, we applied an estimate derived from our average costs. We believe that the use of this methodology is a reasonably accurate method for calculating fuel and trip-related maintenance costs. Because our aircraft are used primarily for business travel, we do not include the fixed costs that do not change based on usage, such as pilots’ salaries, our aircraft purchase costs, and the cost of maintenance not related to trips.

 
 (c) 

These amounts reflect the incremental costs of personal expenses of directors incurred while on business travel and related imputed income to the director for his or her income tax purposes. We reimburse the director for the additional income taxes imposed on the director in these circumstances.

(d)

With respect to Messrs. HerringerMr. Hassan, reflects the costs of gifts given to him and Holley, amounts also reflect incremental costs incurredrelated tax gross-up in connection with guests accompanying directors on business travel and related imputed income to the director for their income tax purposes.his retirement from our Board. We reimburse the director for the additional income taxes imposed on the director in these circumstances.

 
(d)

Amounts reflect the costs of gifts given to the directors, including, with respect to Mr. Herringer, costs and related taxgross-up for gifts given to him related to his retirement from our Board.

(e)

Amounts reflect dividends accrued on vested/deferred RSUs granted prior to 2011 as the impact of dividends was not considered in determining the grant date fair values of these awards for purposes of reporting compensation in the “Stock Awards” column in the “Director Compensation Table” in the Company’s proxy statements in prior years because we did not pay dividends at the time of grant.

 

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Security Ownership of Directors and Executive Officers

 

 

 

 

 

Security Ownership of Directors and Executive Officers

The following table sets forth certain information regarding the beneficial ownership of our Common Stock as of March 20, 202018, 2022 by: (i) each current director and nominee; (ii) our Named Executive Officers, or NEOs (as specified on page 38)41); and (iii) all of our current directors and executive officers as a group. There were 587,762,539533,784,806 shares of our Common Stock outstanding as of March 20, 2020.18, 2022. None of our directors, nominees, NEOs, or executive officers, individually or as a group, beneficially owns greater than 1% of our outstanding shares of Common Stock.

 

  

 

Amgen Inc.
Common Stock
(1)(2)

 

   

 

Amgen Inc.
Common Stock
(1)(2)

 

 

Beneficial Owner

  

 

Total Common Stock

Beneficially Owned

 

   

 

              Shares Acquirable

Within 60 Days

 

   

 

              Percent  

of Total  

 

   

 

Total Common Stock

Beneficially Owned

 

   

 

              Shares Acquirable

Within 60 Days

 

   

 

              Percent  

of Total  

 

 

Non-Employee Directors and Nominees

        

 

  

 

  

 

Wanda M. Austin

  

 

2,348

 

  

 

0

 

  

 

*  

   4,031    0    *   

Brian J. Druker(3)

  

 

0

 

  

 

0

 

  

 

*  

   0    0    *   

Robert A. Eckert(3)

  

 

20,435

 

  

 

20,000

 

  

 

*  

   20,435    20,000    *   

Greg C. Garland

  

 

8,178

 

  

 

0

 

  

 

*  

   9,861    0    *   

Fred Hassan

  

 

8,345

 

  

 

0

 

  

 

*  

Charles M. Holley, Jr.(3)(4)

   1,260    0    *   

Rebecca M. Henderson

  

 

8,150

 

  

 

5,000

 

  

 

*  

S. Omar Ishrak

   935    0    *   

Charles M. Holley, Jr.(3)

  

 

1,260

 

  

 

0

 

  

 

*  

Tyler Jacks(3)

   2,727    0    *   

Tyler Jacks

  

 

1,890

 

  

 

0

 

  

 

*  

Ellen J. Kullman(3)

   410    0    *   

Ellen J. Kullman

  

 

410

 

  

 

0

 

  

 

*  

Amy E. Miles(3)

   408    0    *   

Ronald D. Sugar(3)

  

 

20,000

 

  

 

20,000

 

  

 

*  

   0    0    *   

R. Sanders Williams

  

 

4,988

 

  

 

0

 

  

 

*  

   5,246    0    *   

      

        

 

  

 

  

 

Named Executive Officers

        

 

  

 

  

 

Robert A. Bradway

  

 

907,651

 

  

 

457,906

 

  

 

*  

   1,068,652    498,943    *   

Murdo Gordon

  

 

6,510

 

  

 

0

 

  

 

*  

   71,988    38,419    *   

David W. Meline

  

 

116,977

 

  

 

79,547

 

  

 

*  

David M. Reese

  

 

37,721

 

  

 

22,200

 

  

 

*  

   95,624    64,039    *   

Jonathan P. Graham

  

 

84,109

 

  

 

54,357

 

  

 

*  

Peter H. Griffith

   14,286    10,537    *   

All current directors, NEOs and executive officers as a group (21 individuals)(4)

   

 

1,400,434

 

 

 

   

 

725,193

 

 

 

   

 

*  

 

 

Esteban Santos

   144,350    99,414    *   

All current directors, NEOs and executive officers as a group (20 individuals)(5)

   1,614,555    864,460    *   

 

*

Less than 1%.

(1) 

Information in this table is based on our records and information provided by directors, NEOs, executive officers, and in public filings. Unless otherwise indicated in the footnotes and subject to community property laws, where applicable, each of the directors and nominees, NEOs, and executive officers has sole voting and/or investment power with respect to such shares, including shares held in trust.

(2)

Includes shares which the individuals shown have the right to acquire (a) upon vesting of restricted stock units, or RSUs, and related dividend equivalents (excluding fractional shares), where the shares are issuable as of March 18, 2022, or within 60 days thereafter, and (b) upon exercise of stock options that are vested as of March 18, 2022, or within 60 days thereafter, as set forth in the table below. Such shares are deemed to be outstanding in calculating the percentage ownership of such individual (and the group), but are not deemed to be outstanding as to any other person. Dividend equivalents credited on RSUs are deemed reinvested and are paid out with the vested RSUs in shares of our Common Stock.

 

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Security Ownership of Directors and Executive Officers

 

 

 

 

 

(2)(3)

Includes shares which the individuals shown have the right to acquire (a) upon vesting of restricted stock units, or RSUs, and related dividend equivalents (excluding fractional shares), where the shares are issuable as of March 20, 2020, or within 60 days thereafter, and (b) upon exercise of stock options that are vested as of March 20, 2020, or within 60 days thereafter, as set forth in the table below. Such shares are deemed to be outstanding in calculating the percentage ownership of such individual (and the group), but are not deemed to be outstanding as to any other person. Excludes vested RSUs, and related dividend equivalents, for which receipt has been deferred by certain of thenon-employee directors to a date later than 60 days after March 20, 2020. Dividend equivalents credited on RSUs are deemed reinvested and are paid out with the vested RSUs in shares of our Common Stock.18, 2022.

 

Name  

RSUs and Dividend

Equivalents Included

     

            Stock  Options

Included

 

RSUs and Dividend  

Equivalents Excluded  

        Because of Deferrals(5)  

   

RSUs and Dividend

Equivalents Included

 

     

Stock Options

Included

 

     

RSUs and Dividend   

Equivalents Excluded   

Because of Deferrals(6)   

 

 

Wanda M. Austin

   0      0   0      0      0      0   

Brian J. Druker

   0      0   1,873      0      0      3,745    

Robert A. Eckert

   0      20,000   10,750      0      20,000      13,606    

Greg C. Garland

   0      0   0      0      0      0   

Fred Hassan

   0      0   0   

Charles M. Holley, Jr.

   0      0      5,799    

Rebecca M. Henderson

   0      5,000   13,855   

Charles M. Holley, Jr.

   0      0   3,128   

S. Omar Ishrak

   0      0      0    

Tyler Jacks

   0      0   8,566      0      0      9,997    

Ellen J. Kullman

   0      0   4,993      0      0      8,202    

Amy E. Miles

   0      0      857    

Ronald D. Sugar

   0      20,000   14,636      0      0      17,301    

R. Sanders Williams

   0      0   0      0      0      0   

Robert A. Bradway

   15,565      442,341   0      15,355      483,588      0   

Murdo Gordon

   0      0   0      2,841      35,578      0   

David W. Meline

   4,821      74,726   0   

David M. Reese

   2,862      19,338   0      3,229      60,810      0   

Jonathan P. Graham

   3,323      51,034   0   

Peter H. Griffith

   1,185      9,352      0   

Esteban Santos

   3,816      95,598      0   

 

(3)(4)

Shares held through the Holley Family Trust.

(4)(5)

Includes 181,462174,399 shares (excluding fractional shares) held by the fivefour executive officers who are not NEOs and who have a right to acquire such shares upon the vesting of RSUs that have not been deferred to a date later than 60 days after March 20, 2020,18, 2022, or upon exercise of vested stock options as of March 20, 2020,18, 2022, or within 60 days thereafter. All current directors, NEOs, and executive officers as a group have the right to acquire a total of 32,84331,810 shares upon vesting of RSUs, and related dividend equivalents, where the shares are issuable as of March 20, 2020,18, 2022, or within 60 days thereafter and 692,350832,650 shares upon exercise of stock options that are vested as of March 20, 2020,18, 2022, or within 60 days thereafter.

(5)(6) 

Excludes fractional shares which are paid out in cash on the applicable payout date.

 

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Security Ownership of Certain Beneficial Owners

 

 

 

 

 

Security Ownership of Certain Beneficial Owners

The following table shows the number of shares of our Common Stock owned by each person or entity known to the Company to be the beneficial owners of more than 5% of our Common Stock as of March 20, 2020,18, 2022, based on a review of publicly available statements of beneficial ownership filed with the Securities and Exchange Commission, or SEC, on Schedules 13D and 13G through March 20, 2020.18, 2022.

 

   Common Stock
Beneficially Owned
 
  Name and Address of Beneficial Owner  Number of Shares                 Percent  of Total(1)   

  The Vanguard Group(2)

  100 Vanguard Blvd.

  Malvern, PA 19355

   48,471,525      8.2%  

  BlackRock, Inc.(3)

  55 East 52nd Street

  New York, NY 10055

   46,256,497      7.9%  

  Capital Research Global Investors(4)

  333 South Hope Street

  Los Angeles, CA 90071

   35,337,639      6.0%  
   

 

Common Stock
Beneficially Owned

 

 
  Name and Address of Beneficial Owner  

 

Number of Shares

 

     

 

Percent of Total(1)  

 

 

  BlackRock, Inc.(2)

  55 East 52nd Street

  New York, NY 10055

   50,046,345      9.4%  

  The Vanguard Group(3)

  100 Vanguard Blvd.

  Malvern, PA 19355

   46,661,009      8.7%  

  State Street Corporation(4)

  State Street Financial Center

  One Lincoln Street

  Boston, MA 02111

   30,221,708      5.7%  

 

(1) 

The “Percent of Total” reported in this column has been calculated based upon the numbers of shares of Common Stock outstanding as of March 20, 2020,18, 2022, and may differ from the “Percent of Class” reported in statements of beneficial ownership filed with the SEC.

(2) 

The amounts shown and the following information was provided by The Vanguard GroupBlackRock, Inc. pursuant to a Schedule 13G/A filed with the SEC on February 12, 2020. The Vanguard Group1, 2022. BlackRock, Inc. reports that it has sole voting power over 919,96343,968,202 of these shares and sole dispositive power over 47,432,94150,046,345 shares.

(3) 

The amounts shown and the following information was provided by BlackRock, Inc.The Vanguard Group pursuant to a Schedule 13G/A filed with the SEC on February 5, 2020. BlackRock, Inc.9, 2022. The Vanguard Group reports that it has sole voting power over 40,231,1680 of these shares, shared voting power over 954,537 of these shares, sole dispositive power over 44,278,644 of these shares, and soleshared dispositive power over 46,256,4972,382,365 of these shares.

(4) 

The amounts shown and the following information was provided by Capital Research Global InvestorsState Street Corporation pursuant to a Schedule 13G/A filed with the SEC on February 14, 2020. Capital Research Global Investors10, 2022. State Street Corporation reports that it has sole voting power over 35,337,2060 of these shares, , andshared voting power over 21,561,789 of these shares, sole dispositive power over all 35,337,6390 of these shares, and shared dispositive power over 30,147,007 of these shares.

 

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Item 3 — Ratification of Selection of Independent Registered Public  Accountants

 

 

 

 

 

Item 3

Ratification of Selection of Independent Registered Public Accountants

 

 

The Audit Committee of the Board of Directors, or Board, has sole authority for the appointment, compensation, and oversight of the work of the independent registered public accountants. The Audit Committee has selected Ernst & Young LLP, or EY, as our independent registered public accountants for the fiscal year ending December 31, 2020,2022, and the Board has directed that management submit this selection for ratification by the stockholders at our 20202022 Annual Meeting of Stockholders, or Annual Meeting. EY has served as our independent registered public accounting firm and has audited our financial statements since the Company’s inception in 1980. The Audit Committee periodically considers whether there should be a rotation of our independent registered public accountants. Each year, the Audit Committee evaluates the qualifications and performance of the Company’s independent registered public accountants and determines whether tore-engage the current independent registered public accountants or whether there should be a rotation of our independent registered public accountants. In doing so, the Audit Committee considers the quality and efficiency of the services provided by the independent registered public accountants, their technical expertise, and knowledge of our complex global operations and industry.industry, the appropriateness of EY’s fees, as well as external data on audit quality and performance, including independent assessments by the Public Company Accounting Oversight Board (PCAOB) on EY and its peer firms. Based on this evaluation,the members of the Audit Committee believe that the continued retention of EY as our independent registered public accountants for 2022 is in the best interests of the Company and its stockholders.

In conjunction with the mandated rotation of EY’s lead engagement partner, the Audit Committee and its

chairperson Chair are directly involved in the

selection of EY’s new lead engagement partner. The process for selection of EY’s lead engagement partner involves a meeting between the Audit Committee’s chairpersonChair and the candidate, as well as an assessment by the full Audit Committee and management. To ensure a smooth transition, the new lead engagement partner shadows the lead engagement partner and attends Audit Committee meetings in advance of assuming the responsibilities. The selection of a new lead engagement partner most recently occurred in 2021 and was effective after the completion of our 2021 Annual Report on Form 10-K. A representative of EY is expected to be in attendance at the Annual Meeting and will have an opportunity to make a statement and respond to appropriate questions.

Stockholder ratification of the selection of EY as our independent registered public accountants is not required by the Amgen Inc. Restated Certificate of Incorporation, the Amended and Restated Bylaws of Amgen Inc., or otherwise. However, the Board is submitting the selection of EY to our stockholders for ratification because we believe it is a matter of good corporate governance practice. If our stockholders fail to ratify the selection, the Audit Committee will reconsider whether or not to retain EY, but still may retain them. Even if the selection is ratified, the Audit Committee in its discretion may direct the appointment of a different independent registered public accounting firm at any time during the year if the Audit Committee determines that such a change would be in our best interests and that of our stockholders.

 

 

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” RATIFICATION OF OUR INDEPENDENT REGISTERED PUBLIC ACCOUNTANTS.

 

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Audit Matters

 

 

 

 

 

Audit Matters

Audit Committee Report

 

 

The Audit Committee has reviewed and discussed with management the Company’s audited consolidated financial statements as of and for the year ended December 31, 2019.2021.

The Audit Committee has also discussed with Ernst & Young LLP, or EY, the matters required to be discussed by the applicable requirements of the Public Company Accounting Oversight Board (PCAOB) and the Securities and Exchange Commission.

The Audit Committee has received and reviewed the written disclosures and the letter from EY required by the applicable requirements of the

PCAOB regarding EY’s communication with the Audit Committee concerning independence and has discussed with EY their independence.

Based on the reviews and discussions referred to above, the Audit Committee recommended to the Board of Directors that the audited consolidated financial statements referred to above be included in the Company’s Annual Report onForm 10-K for the year ended December 31, 20192021 for filing with the Securities and Exchange Commission.

 

 

Audit Committee of the Board of Directors

Charles M. Holley, Jr., ChairmanChair

Wanda M. Austin

Fred Hassan

Ellen J. Kullman

Amy E. Miles

Independent Registered Public Accountants

 

The following table presents fees for professional services provided or to be provided by EY for audits of the years ended December 31, 20192021 and December 31, 2018,2020, and fees for other services rendered by EY during these periods.

 

  2019     2018     2021     2020   

Audit

  $8,049,000     $7,995,000    $8,784,000     $8,860,000   

Audit-Related

   410,000      765,000     418,000      387,000   

Tax

   50,000      0     3,000      5,000   

All Other Fees

   0      0     0      0   
  

Total Fees

  $8,509,000     $8,760,000    $9,205,000     $9,252,000   

 

Included in Audit fees above are professional services associated with the integrated audit of our consolidated financial statements and our internal control over financial reporting and the statutory audits of various subsidiaries of the Company. Audit-Related fees are attributable to assurance and related services that are also performed by our independent registered public accountants, including attest related services, accounting consultations, and audits of employee benefit plan information. The Audit Committee has considered whether the Audit-Related services provided by EY are compatible with maintaining that firm’s independence. Tax fees include assistance with various corporate tax compliance andtax-related matters.

The Audit Committee has approved all audit and permissiblenon-audit services prior to such services being provided by EY. The Audit Committee, or the ChairmanChair of the Audit Committee who has been granted authority by the Audit Committee, approves each audit ornon-audit service prior to the engagement of EY for such service. Each such service approved by the ChairmanChair of the Audit Committee is presented to the entire Audit Committee at a subsequent meeting.

 

 

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Annual Report on Form 10-K

 

 

 

 

 

Annual Report on Form10-K

 

The Company’s Annual Report on Form10-K for fiscal 2019,2021, which contains the consolidated financial statements of the Company for fiscal 2019,2021, accompanies this proxy statement, but is not a part of the Company’s soliciting materials.

Stockholders may obtain, without charge, a copy of the Company’s Annual Report on Form10-K for fiscal 2019,2021, filed with the Securities and Exchange Commission, including the financial statements and schedules thereto, without the accompanying

exhibits, by writing to: Investor Relations, Senior Manager,Director, Amgen Inc.,

One Amgen Center Drive, Thousand Oaks, CA 91320-1799, or contact Investor Relations by telephone at(805) 447-1060 or email at investor.relations@amgen.com. The Company’s Annual Report on Form10-K is also available online on the Company’s website atwww.amgen.com.(1) A list of exhibits is included in the Form10-K and exhibits are available online on the Company’s website or may be obtained from the Company upon payment to the Company of the cost of furnishing them.

 

 

(1)

Reference to our website is not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement.

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 Item 4 — Stockholder Proposal to Require an Independent Board  Chair 

Item 4

Stockholder Proposal to Require an Independent Board Chair

A stockholder has informed the Company that it intends to present the proposal set forth below at our 2020 Annual Meeting of Stockholders, or Annual Meeting. If the stockholder (or its “qualified representative” as determined under applicable law and our Amended and Restated Bylaws of Amgen Inc., or Bylaws) are in attendance at the Annual Meeting and properly submit the proposal for a vote, then the stockholder proposal will be voted upon at the Annual Meeting.

The stockholder proposal was submitted by United Church Funds, a member of the Investors for Opioid and Pharmaceutical Accountability (IOPA), an investor coalition. IOPA did notco-file the proposal. United Church Funds is the owner of 3,611 shares of our Common Stock as of December 3, 2019, with an address of 475 Riverside Drive, Suite 1020, New York, NY 10115.

In accordance with the Federal securities laws, the stockholder proposal and supporting statement is presented below as submitted by the stockholder, quoted verbatim and is in italics. The Company disclaims all responsibility for the content of the proposal and the supporting statement, including other sources referenced in the supporting statement.

FOR THE REASONS STATED IN THE BOARD OF DIRECTOR’S, OR BOARD, RESPONSE, WHICH FOLLOWS THE STOCKHOLDER PROPOSAL, THE BOARD STRONGLY AND UNANIMOUSLY RECOMMENDS THAT YOU VOTE “AGAINST” THE STOCKHOLDER PROPOSAL

Stockholder Proposal:

Amgen—Independent Chair & CEO

RESOLVED:The shareholders request the Board of Directors to adopt as policy, and amend the bylaws as necessary, to require the Chair of the Board of Directors, whenever possible, to be an independent member of the Board. This policy would be phased in for the next CEO transition.

If the Board determines that a Chair who was independent when selected is no longer independent, the Board shall select a new Chair who satisfies the requirements of the policy within a reasonable amount of time. Compliance with this policy is waived if no independent director is available and willing to serve as Chair.

Supporting Statement:

We believe:

The role of the CEO and management is to run the company.

The role of the Board of Directors is to provide independent oversight of management and the CEO.

There is a potential conflict of interest for a CEO to have a past CEO an inside director act as Chair.

As Andrew Grove, Intel’s former chair, stated, “The separation of the two jobs goes to the heart of the conception of a corporation. Is a company a sandbox for the CEO, or is the CEO an employee? If he’s an employee, he needs a boss, and that boss is the Board. The Chairman runs the Board. How can the CEO be his own boss?”

In our view, shareholders are best served by an independent Board Chair who can provide a balance of power between the CEO and the Board. The primary duty of a Board of Directors is to oversee the management of a company on behalf of shareholders. A CEO serving as Chair can result in excessive management influence on the Board and weaker oversight of management. We urge Amgen’s Board to take the opportunity to appoint a new independent Board Chair in the next round of succession.

Amgen’s financial involvement with industry groups that advocate against biosimilars1 may run counter to the company’s endorsement of balanced and accurate policy information on biosimilars and its own interests as a developer of biosimilar treatments. These types of inconsistencies and the reputational damage that may ensue indicate the need for governance best practices. An independent Board Chair can demonstrate our company’s concern for proper oversight and governance.

Numerous institutional investors recommend independence for these two roles. For example, California’s Retirement System CalPERS’ Principles & Guidelines encourage separation, even with a lead director in place. In addition investor interest in this governance practice is growing.

According to ISS “2017 Board Practices”, (March 2017), 58% of S&P 1,500 firms separate these two positions and the number of companies separating these roles is growing.

To simplify the transition, this policy would be phased in and implemented when the next CEO is chosen.

1

https://www.washingtonpost.com/business/economy/drugmakers-alleged-scare-tactics-may-hold-back-competition/2019/01/09/612ac994-046d-IIe9-9I22- 82e98f9Iee6f_story.html

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 Item 4 — Stockholder Proposal to Require an Independent Board  Chair 

Board Response to Item 4: Stockholder Proposal to Require an Independent Board Chair

The Board of Directors recommends a vote “AGAINST” the Stockholder Proposal.

Our Board of Directors has considered this proposal and has concluded that it is not in the best interests of the Company or its stockholders to prohibit the Chief Executive Officer, or CEO, of the Company from serving as the Chairman andmandate that the Chairman be an independent director, as broadly defined by the proponent.

The Board’s recommendation to vote “AGAINST” the Stockholder Proposal is based on the following reasons:

The Company’s governance documents give the Board discretion in determining whether to separate or combine the roles of the Chairman and CEO. This flexibility permits the Board to choose a leadership structure that can be tailored to the strengths of the Company’s officers and directors and to best address the Company’s evolving and highly complex business. The Board conducts annual evaluations of the Company’s leadership structure and determined that the Company and its stockholders are best served at this time by having Robert A. Bradway serve as both Chairman and CEO, coupled by a separate active lead independent director (currently served by Robert A. Eckert) for the following reasons:

Mr. Bradway is most familiar with our business and the unique challenges we face. Mr. Bradway’sday-to-day insight into our challenges facilitates a timely deliberation by the Board of important matters.

Mr. Bradway has and will continue to identify agenda items and lead effective discussions on the important matters affecting us. Mr. Bradway’s knowledge and extensive experience regarding our operations and the highly-regulated industries and markets in which we compete position him to identify and prioritize matters for Board review and deliberation.

As Chairman and CEO, Mr. Bradway serves as an important bridge between the Board and management and provides critical leadership for carrying out our strategic initiatives and confronting our challenges. The Board believes that Mr. Bradway brings a unique, stockholder-focused insight to assist the Company to most effectively execute its strategy and business plans to maximize stockholder value.

The strength and effectiveness of the communications between Mr. Bradway as our Chairman and Mr. Eckert as our lead independent director result in comprehensive Board oversight of the issues, plans, and prospects of our Company.

This leadership structure provides the Board with more complete and timely information about the Company, a unified structure and consistent leadership direction internally and externally and provides a collaborative and collegial environment for Board decision making.

Annual Assessment. The Board reviews the Company’s leadership structure on an annual basis and reserves the right to separate the role of the Chairman and CEO at any time.

Mechanisms to Ensure Independent Oversight.This proposal is premised on the incorrect assumption that having a current or former executive serving as Chairman limits our Board’s oversight and evaluation of the CEO and other senior management. This is not the case at Amgen. We have numerous mechanisms that ensure independent oversight of the Company’s affairs and that facilitate communication with, and independent evaluation of, senior management, including:

We have an active “lead independent director” elected annually by and from the independent directors and strong Board and committee involvement to provide sound and robust oversight of management. Mr. Eckert currently serves as the lead independent director. His robust set of duties and authority are described in detail under “Corporate Governance—Leadership Structure.” This leadership structure provides a means for regular dialogue among our independent directors, ensures an effective bridge between independent directors and Mr. Bradway and provides a channel through which independent directors may raise and elevate significant concerns to management. Key responsibilities of our lead independent director include:

Approving meeting agendas for the Board;

Assuring that there is sufficient time for discussion of all meeting agenda items;

Previewing the information to be provided to the Board;

Having the authority to call meetings of the independent directors;

Organizing and leading the Board’s evaluation of the CEO;

Serving as a liaison between the Chairman and the independent directors;

Leading the Board’s annual self-assessment;

Ensuring that he/she is available for consultation and direct communication, if requested by major stockholders; and

Presiding at meetings of the Board at which the Chairman is not present, including executive sessions of the independent directors.

In addition to the responsibilities outlined above, the lead independent director:

Meets with the Chairman prior to each regular meeting of the Board and its committees to discuss, provide input on, and approve the agendas;

With the Chairman, determines presenters for attendance at Board meetings;

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 Item 4 — Stockholder Proposal to Require an Independent Board  Chair 

Hasone-on-one discussions with each independent director, including as part of the Board’s annual evaluation process;

Attends all committee meetings, including those committees for which he is not a member (at his discretion) and is provided with access to all committee materials;

Has the authority to engage independent consultants;

Is regularly apprised of inquiries from stockholders;

Interviews Board candidates; and

Has an increased role in crisis management, as appropriate.

Regular Communications.The lead independent director engages in regular communication between the independent directors and Mr. Bradway, keeping Mr. Bradway apprised of any concerns, issues, or determinations made during the independent sessions, and consults with Mr. Bradway on other matters pertinent to the Company and the Board.

Independent Board.We have diverse, experienced, and skilled directors. Ten of our eleven director nominees (91%) are independent as defined by The NASDAQ Stock Market listing standards and the requirements of the Securities and Exchange Commission, with Mr. Bradway, our CEO, representing the sole exception.

Independent Committee Leadership. All members of the Board’s key committees (Audit, Compensation and Management Development, Corporate Responsibility and Compliance, and Governance and Nominating) are independent. In addition:

Each committee chair meets with management to review and refine agenda, add topics of interest, and review and comment on materials to be delivered to the committee;

Every independent director has access to all committee materials;

Each committee chair provides a report summarizing committee meetings to the full Board at each regular meeting of the Board;

Each committee meeting includes adequate time for executive session and the committees meet in executive session on a

regular basis with no members of management present (unless otherwise requested by the committee); and

Each committee effectively manages its Board-delegated duties and communicates regularly with the Chairman and members of management.

Independent Directors Sessions. A meeting of the independent directors is scheduled at every regular Board meeting and the independent directors meet in an executive session without Mr. Bradway to review Company performance, management effectiveness, proposed programs and transactions, and the Board meeting agenda items. These independent sessions are organized and chaired by our lead independent director and our lead independent director provides direct feedback to Mr. Bradway after these executive sessions.

Stockholder Engagement. Each year, we reach out to stockholders representing approximately 50% of our outstanding shares so that we are fully informed and able to carefully weigh the views of our stockholders. During our stockholder engagement discussions, many of our stockholders expressed support and confidence in our current governance structure. We have a long history of proactively responding to stockholder concerns and have strong stockholder rights, including proxy access, a majority voting policy for director elections, and providing stockholders the right to call special meetings of stockholders and act by written consent. Stockholders may also communicate with our Board directly as described on page 21.

Given the Company’s independent Board structure, the comprehensive role of the lead independent director and other strong corporate governance practices, the Board believes that separating the positions of Chairman and CEO would weaken the Company’s current leadership structure. The proposal would also deprive the Board of the valuable flexibility to exercise its business judgment in selecting the individual best suited to serve as Chairman in the future. Therefore, the Board does not believe that implementing the proposal would be in the best interests of the Company or its stockholders.

THE BOARD OF DIRECTORS RECOMMENDS A VOTE “AGAINST” THE STOCKHOLDER PROPOSAL TO REQUIRE AN INDEPENDENT BOARD CHAIR.

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Certain Relationships and Related Transactions

 

 

 

 

 

Certain Relationships and Related Transactions

 

Under our written Approval of Related Party Transactions policy, a Securities and Exchange Commission, or SEC, related party transaction (as defined below) may be consummated or may continue only if the Audit Committee approves or ratifies the transaction in accordance with the guidelines set forth in the policy. The policy applies to: (1) any person who is, or at any time since the beginning of our last fiscal year was, a member of our Board of Directors, or Board, one of our executive officers or a nominee to become a member of our Board; (2) any person who is known to be the beneficial owner of more than 5% of any class of our voting securities; (3) any immediate family member, as defined in the policy, of, or sharing a household with, any of the foregoing persons; and (4) any firm, corporation or other entity in which any of the foregoing persons is employed, or is a partner or principal or in a similar position or in which such person has a 5% or greater beneficial ownership interest.

All potential related party transactions are presented to the Audit Committee for its consideration and, if the Audit Committee deems it appropriate, approval. The Audit Committee considers all relevant facts and circumstances available to it, including the recommendation of management. No member of the Audit Committee participates in any review, consideration, or approval of any related party transaction involving such member or any of his or her immediate family members, except that such member is required to provide all material information concerning the related party transaction to the Audit Committee.

Related party transactions may be preliminarily entered into by management subject to ratification by the Audit Committee; provided that if ratification shall not be forthcoming, management shall make all reasonable efforts to cancel or annul such transaction. At each scheduled meeting of the Audit Committee, management is required to update the Audit Committee as to any material changes to any approved or ratified related party transaction. A “SEC Related Party Transaction” is defined in the policy as a transaction, arrangement or relationship, or series of similar transactions, arrangements or relationships (including but not limited to any indebtedness or guarantee of indebtedness) between us and any of the persons listed in the first paragraph of this section. A related party transaction also includes any material amendment or modification to an existing related party transaction.

The Audit Committee has excluded each of the following related party transactions under the terms of our Approval of Related Party Transactions policy:

 

1.

Any matters related to compensation or benefits to the extent such compensation or benefits would not be required to be disclosed under Item 404 of RegulationS-K under the Securities Act of 1933;

 

2.

Transactions involving less than $120,000 (or such different amount as may require disclosure or approval under any future amendment to the rules and regulations of the SEC, including Item 404 of RegulationS-K, or the listing requirements of The NASDAQ Stock Market LLC, including Rule 5630) when aggregated with all similar transactions; or

 

3.

Transactions approved by another independent committee of the Board.

In deciding whether to approve or ratify a related party transaction, the Audit Committee will consider the following factors:

 

Whether the terms of the transaction are (i) fair to the Company and (ii) at least as favorable to the Company as would apply if the transaction did not involve a related party;

 

Whether there are demonstrable business reasons for the Company to enter into the transaction;

 

Whether the transaction would impair the independence of an outside director; and

 

Whether the transaction would present an improper conflict of interest for any director or executive officer, taking into account the size of the transaction, the overall financial position of the related party, the direct or indirect nature of the related party’s interest in the transaction and the ongoing nature of any proposed relationship, and any other factors the Audit Committee deems relevant.

Separately, to avoid even the appearance of a conflict of interest related to service on our Board, we require appropriate reporting of such service in scientific publications and presentations.

We are

Transactions with Related Persons

Leandro Grimaldi, who is the son-in-law of Nancy A. Grygiel, an executive officer of the Company, is employed by us as Business Performance Director. Dr. Grimaldi’s compensation earned in 2021 consisted of $146,154 in base salary, $44,000 in annual cash incentive awards, a sign-on cash bonus and cash award of $120,500, grants of restricted stock units valued at $50,000 and $7,000 respectively, on

the grant date, and standard relocation benefits. This transaction did not awarerequire the review or approval of any related party transactions since the beginningAudit Committee pursuant to our Approval of fiscal year 2019 that require disclosure under the SEC’s rules.Related Party Transactions policy because it was reviewed by our Compensation and Management Development Committee.

 

 

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Information Concerning Voting and Solicitation

 

 

 

 

 

Information Concerning Voting and Solicitation

General

 

 

The enclosed proxy is solicited on behalf of the Board of Directors, or Board, of Amgen Inc., a Delaware corporation, for use at our 20202022 Annual Meeting of Stockholders, or Annual Meeting, to be held on Tuesday, May 19, 2020,17, 2022, at 11:00 A.M., Pacific Time, or any continuation, postponement, or adjournment thereof, for the purposes discussed in this proxy statement and in the accompanying Notice of Annual Meeting of Stockholders and any business properly brought before the Annual Meeting. Proxies are solicited to give all stockholders of record an opportunity to vote on matters properly presented at the Annual Meeting. After careful consideration, in light of the on-going developments related to the COVID-19 pandemic and governmental decrees that in-person gatherings be postponed or canceled, and in the best interests of public health and the health and safety of our stockholders, Board of Directors, and employees, ourOur 2022 Annual Meeting, will be held solely by remote communication via the internet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. YouWhile you will not be able to attend the Annual Meeting in person.person, stockholders will, to the extent possible, be afforded the same rights and opportunities to participate at the virtual meeting similarly to how they would participate at an in-person meeting.

Stockholders or their proxyholders may participate, vote, and examine our list of stockholders at our Annual Meeting via the Internetinternet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022 and using your control number.

Pursuant to the rules adopted by the Securities and Exchange Commission, we have elected to provide access to our proxy materials over the Internet.internet. Accordingly, we are sending a Notice Regarding the Availability of Proxy Materials, or Notice, to certain of our stockholders of record, and we are sending a paper copy of the proxy materials and proxy card to other stockholders of record who we believe would prefer receiving such materials in paper form. Brokers and other nominees who hold shares on behalf of beneficial owners will be sending their own similar Notice. Stockholders will have the ability to access the proxy materials on the website referred to in the Notice or request to receive a printed set of the proxy materials. Instructions on how to request a printed copy by mail or electronically may be found on the Notice and on the website referred to in the Notice, including an option to request paper copies on an ongoing basis. We intend to make this proxy statement available on the Internetinternet and to mail the Notice, or to mail the proxy statement and proxy card, as applicable, on or about April 7, 2020,5, 2022, to all stockholders entitled to notice of and to vote at the Annual Meeting.

Important Notice Regarding the Availability of Proxy Materials for the 20202022 Stockholder Meeting to Be Held on May 19, 2020.17, 2022.

This proxy statement, our 20192021 annual report and our other proxy materials are available at: www.proxyvote.com. At this website, you will find a complete set of the following proxy materials: notice of 20202022 Annual Meeting of Stockholders; proxy statement; 20192021 annual report; and form proxy card. You are encouraged to access and review all of the important information contained in the proxy materials before submitting a proxy or voting at the meeting.

What Are You Voting On?

You will be entitled to vote on the following proposals at the Annual Meeting:

 

The election of the 1112 director nominees named herein to serve on our Board for a term of office expiring at the 20212023 annual meeting of stockholders;

 

The advisory vote to approve our executive compensation;

 

The ratification of the selection of Ernst & Young LLP as our independent registered public accountants for the fiscal year ending December 31, 2020;

One stockholder proposal, if properly presented at the Annual Meeting;2022; and

 

Any other business as may properly come before the Annual Meeting.

Who Can Vote

The Board has set March 20, 2020,18, 2022, as the record date for the Annual Meeting. You are entitled to notice and to vote if you were a stockholder of record of our Common Stock, $.0001 par value per share, or Common Stock, as of the close of business on March 20, 2020.18, 2022. You are entitled to one vote on each nominee’s election and on each other proposal for each share of Common Stock you held on the record date. Your shares may be voted at the Annual Meeting only if you are in attendance or your shares are represented by a valid proxy.

Difference Between a Stockholder of Record and a “Street Name” Holder

If your shares are registered directly in your name in the records of the Company’s transfer agent, you are considered the stockholder of record with respect to those shares.

If your shares are held in a stock brokerage account or by a bank, trust, or other nominee, then the broker, bank, trust, or other nominee is considered to be the stockholder of record with respect to those shares. However, you are still considered to be the beneficial owner of those shares, and your shares are said to be held in “street name.” Street name holders generally cannot submit a proxy or vote their shares directly and must instead instruct the broker, bank, trust, or other nominee how to vote their shares using the methods described below under “Voting Your Shares.”

Shares Outstanding and Quorum

At the close of business on March 20, 2020,18, 2022, there were 587,762,539533,784,806 shares of our Common Stock outstanding and entitled to vote at the Annual Meeting. The presence of the holders of a majority of the outstanding shares of our Common Stock entitled to vote constitutes a

 

 

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the outstanding shares of our Common Stock entitled to vote constitutes a quorum, which is required to hold and conduct business at the Annual Meeting. Shares are counted as present at the Annual Meeting if:

 

You are in attendance at the Annual Meeting; or

 

Your shares are represented by a properly authorized and submitted proxy (submitted by mail, by telephone, or over the Internet)internet).

If you are a record holder and you submit your proxy, regardless of whether you abstain from voting on one or more matters, your shares will be counted as present at the Annual Meeting for the purpose of determining a quorum. If your shares are held in “street name,” your shares are counted as present for purposes of determining a quorum if your broker, bank, trust, or other nominee submits a proxy covering your shares. Your broker, bank, trust, or other nominee is entitled to submit a proxy covering your shares as to certain “routine” matters, even if you have not instructed your broker, bank, trust, or other nominee on how to vote on those matters. Please see the subsection “If You Do Not Specify How You Want Your Shares Voted” below. In the absence of a quorum, the Annual Meeting may be adjourned, from time to time, by the chairmanChair of the meeting or by the vote of the holders of a majority of the shares represented thereat, but no other business shall be transacted at such meeting.

Voting Your Shares

You may vote by attending the Annual Meeting and voting or by submitting a proxy. The method of voting by proxy differs (1) depending on whether you are viewing this proxy statement on the Internetinternet or receiving a paper copy and (2) for shares held as a record holder and shares held in “street name.”

Shares Held as a Record Holder. If you hold your shares of Common Stock as a record holder and you are viewing this proxy statement on the Internet,internet, you may submit a proxy over the Internetinternet by following the instructions on the website referred to in the Notice previously mailed to you. You may request paper copies of the proxy statement and proxy card by following the instructions on the Notice. If you hold your shares of Common Stock as a record holder and you are reviewing a paper copy of this proxy statement, you may submit a proxy over the Internetinternet or by telephone by following the instructions on the proxy card, or by completing, dating, and signing the proxy card that was included with the proxy statement and promptly returning it in thepre-addressed, postage-paid envelope provided to you.

Shares Held in Street Name. If you hold your shares of Common Stock in street name, you will receive a Notice from your broker, bank, trust, or other nominee that includes instructions on how to vote your shares. Your broker, bank, trust, or other nominee may allow you to deliver

your voting instructions over the Internetinternet and may also permit you to submit your voting instructions by telephone. In addition, you may

request paper copies of the proxy statement and proxy card from your broker by following the instructions on the Notice provided by your broker, bank, trust, or other nominee.

The Internetinternet(1) and telephone voting facilities will close at 11:59 P.M., Eastern Time, on May 18, 2020.16, 2022. Stockholders who submit a proxy by Internetinternet or telephone need not return a proxy card or the form forwarded by your broker, bank, trust, or other holder of record by mail.

 

YOUR VOTE IS VERY IMPORTANT.

You should submit your proxy even if you plan to

attend the Annual Meeting.

Voting at the Annual Meeting

As discussed previously, after careful consideration, in light of the on-going developments related to the COVID-19 pandemic and governmental decrees that in-person gatherings be postponed or canceled, and in the best interests of public health and the health and safety of our stockholders, Board of Directors, and employees, our Annual Meeting will be held solely by remote communication via the internet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. YouWhile you will not be able to attend the Annual Meeting in person.person, stockholders will, to the extent possible, be afforded the same rights and opportunities to participate at the virtual meeting similarly to how they would participate at an in-person

meeting. To participate, vote, and examine our list of stockholders at the Annual Meeting, you will need to log-in towww.virtualshareholdermeeting.com/AMGN2020AMGN2022 using the control number on the Notice, proxy card, or voting instruction form. Please note that if your shares are held of record by a broker, bank, trust, or other nominee, and you decide to attend and vote at the Annual Meeting, your vote while in attendance at the Annual Meeting will not be effective unless you provide a legal proxy, issued in your name from the record holder (your broker, bank, trust, or other nominee).Even if you intend to attend the Annual Meeting, we encourage you to submit your proxy in advance of the Annual Meeting.Please see the important instructions and requirements below regarding “Attendance at the Annual Meeting.”

To vote at the Annual Meeting, visitwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. For shares held as a record holderor in street name, you will need the control number that appears on your Notice, proxy card, or voting instruction form.

Changing Your Vote

As a stockholder of record, if you submit a proxy, you may revoke that proxy at any time before it is voted at the Annual Meeting. Stockholders of record may revoke a proxy by (i) duly submitting a later-dated proxy over the Internet,internet, by mail, or by telephone, (ii) delivering a written notice of revocation to the attention of the Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799, or (iii) attending the Annual Meeting and voting at the Annual Meeting. Attendance at the Annual Meeting will not, by

 

 

(1) 

Stockholders who submit a proxy through the Internetinternet or telephone should be aware that they may incur costs to access the Internetinternet or telephone, such as usage charges from telephone companies or Internetinternet service providers and that these costs must be borne by the stockholder.

 

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executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799, or (iii) attending the Annual Meeting and voting at the Annual Meeting. Attendance at the Annual Meeting will not, by itself, revoke a proxy. If your shares are held in the name of a broker, bank, trust, or other nominee, you may change your voting instructions by following the instructions of your broker, bank, trust, or other nominee.

If You Receive More Than One Proxy Card or Notice

If you receive more than one proxy card or Notice, it means you hold shares that are registered in more than one account. To ensure that all of your shares are voted, sign and return each proxy card or, if you submit a proxy by telephone or the Internet,internet, submit one proxy for each proxy card or Notice you receive.

How Will Your Shares Be Voted

Stockholders of record as of the close of business on March 20, 2020,18, 2022, are entitled to one vote for each share of our Common Stock held on all matters to be voted upon at the Annual Meeting. All shares entitled to vote and represented by properly submitted proxies received before the polls are closed at the Annual Meeting, and not revoked or superseded, will be voted at the Annual Meeting in accordance with the instructions indicated on those proxies.YOUR VOTE IS VERY IMPORTANT.

If You Do Not Specify How You Want Your Shares Voted

As a stockholder of record, if you submit a signed proxy card or submit your proxy by telephone or Internetinternet and do not specify how you want your shares voted, the proxy holder will vote your shares:

 

FOR the election of the 1112 nominees listed in this proxy statement to serve on our Board for a term of office expiring at the 20212023 annual meeting of stockholders;

 

FOR the advisory vote to approve our executive compensation; and

 

FOR the ratification of the selection of Ernst & Young LLP as our independent registered public accountants for the fiscal year ending December 31, 2020; and

AGAINST the stockholder proposal to require an independent board chair, if properly presented.2022.

A “brokernon-vote” occurs when a nominee holding shares for a beneficial owner has not received voting instructions from the beneficial owner and the nominee does not have discretionary authority to vote the shares. If you hold your shares in street name and do not provide voting instructions to your broker or other nominee, your shares will be considered to be brokernon-votes and will not be voted on any proposal on which your broker or other nominee does not have discretionary authority to vote. Shares that constitute brokernon-votes will be counted as present at the Annual Meeting for the purpose of determining a quorum, but will not be considered entitled to vote on the proposal in question and therefore will have no effect on the outcome of the vote. Brokers generally have discretionary authority to vote on

the ratification of the selection of Ernst & Young LLP as our independent registered public accountants. Brokers, however, do not

have discretionary authority to vote on the election of directors to serve on our Board or on the advisory vote to approve our executive compensation, or on the stockholder proposal.compensation.

In their discretion, the proxy holders named in the proxy solicited by the Company are authorized to vote the proxies in their discretion on any other matters that may properly come before the Annual Meeting and any continuation, postponement, or adjournment thereof. The Board knows of no other items of business that will be presented for consideration at the Annual Meeting other than those described in this proxy statement. In addition, no stockholder nomination was received on a timely basis, so no such matter may be brought to a vote at the Annual Meeting.

Inspector of Election and Counting of Votes

All votes will be tabulated as required by Delaware law, the state of our incorporation, by the inspector of election appointed for the Annual Meeting, who will separately tabulate affirmative and negative votes, abstentions, and brokernon-votes. Shares held by persons attending the Annual Meeting but not voting, shares represented by proxies that reflect abstentions as to one or more proposals, and brokernon-votes will be counted as present for purposes of determining a quorum.

Election of Directors.We have a majority voting standard for the election of directors in an uncontested election, which is generally defined as an election in which the number of nominees does not exceed the number of directors to be elected at the meeting. In the election of directors, you may either vote “for,” “against,” or “abstain” for each nominee. Cumulative voting is not permitted. Under our majority voting standard, in uncontested elections of directors, such as this election, each director must be elected by the affirmative vote of a majority of the votes cast by the shares in attendance at the Annual Meeting or represented by proxy. A “majority of the votes cast” means that the number of votes cast “for” a director nominee exceeds the number of votes cast “against” the nominee. For these purposes, abstentions and brokernon-votes will not count as a vote “for” or “against” a nominee’s election and thus will have no effect in determining whether a director nominee has received a majority of the votes cast. Brokers do not have discretionary authority to vote on this proposal.

If a director nominee is an incumbent director and does not receive a majority of the votes cast in an uncontested election, that director will continue to serve on the Board as a “holdover” director, but must tender his or her resignation contingent upon acceptance by the Board to the Board promptly after certification of the election results of the stockholder vote. The Governance and Nominating Committee of the Board will then recommend to the Board whether to accept the resignation or whether other action should be taken. The Board will act on the tendered resignation, taking into account the recommendation of the Governance and Nominating Committee, and the Board’s decision will be publicly disclosed within 90 days after certification of the election results of the stockholder vote. A director who tenders his or her resignation after failing to receive a majority of the votes cast will not participate in the recommendation of the Governance and

 

 

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election results of the stockholder vote. A director who tenders his or her resignation after failing to receive a majority of the votes cast will not participate in the recommendation of the Governance and Nominating Committee or the decision of the Board with respect to his or her resignation.

Management Proposals (Advisory Vote to Approve Our Executive Compensation and Ratification of Ernst & Young LLP) and Stockholder Proposal..The approval of the advisory vote to approve our executive compensation and the ratification of the selection of Ernst & Young LLP and the stockholder proposal requires the affirmative votes of the holders of a majority of the shares present or represented by proxy at the Annual Meeting and entitled to vote on the matter. Abstentions will have the same effect as votes “against” each proposal.

Because brokers have discretionary authority to vote on the ratification of the selection of Ernst & Young LLP, we do not expect any brokernon-votes in connection with the ratification. Brokers do not have discretionary authority to vote on the advisory vote to approve our executive compensation or the stockholder proposal.compensation. Brokernon-votes, therefore, will have no effect on the advisory votes to approve our executive compensation or the stockholder proposal as brokers are not entitled to vote on such proposalsproposal in the absence of voting instructions from the beneficial owner.

Solicitation of Proxies

We will bear the entire cost of solicitation of proxies, including preparation, assembly, and mailing of this proxy statement, the proxy, the Notice, and any additional information furnished to stockholders. Copies of solicitation materials will be furnished to banks, brokerage houses, fiduciaries, and custodians holding shares of our Common Stock in their names that are beneficially owned by others to forward to those beneficial owners. We may reimburse persons representing beneficial owners for their costs of forwarding the solicitation materials to the beneficial owners. Original solicitation of proxies may be supplemented by telephone, facsimile, electronic mail, or personal solicitation by our directors, officers, or staff members. No additional compensation will be paid to our directors, officers, or staff members for such services. In addition, we have retained D.F. King & Co. to assist in the solicitation of proxies for a fee of approximately $100,000 plus distribution costs and other costs and expenses. A list of stockholders entitled to vote at the Annual Meeting will be available for

examination by any stockholder for any purpose germane to the Annual Meeting at the Company’s principal executive offices at One Amgen

Center Drive, Thousand Oaks, California 91320-1799 during ordinary business hours for the ten days prior to the Annual Meeting and also will be available for stockholders to examine our list of stockholders at our Annual Meeting via the Annual Meeting.internet at www.virtualshareholdermeeting.com/AMGN2022 and using your control number.

Attendance at the Annual Meeting

Our Annual Meeting will be held solely by remote communication via the internet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. You will be able to attend the Annual Meeting virtually, but not in person. The live audio webcast of the Annual Meeting will begin promptly at 11:00 A.M., Pacific Time. Stockholders or their proxyholders may participate, vote, and examine our list of stockholders at our Annual Meeting via the Internetinternet atwww.virtualshareholdermeeting.com/AMGN2020AMGN2022 and using your control number. We encourage our stockholders to access the meeting approximately 15 minutes in advance of the designated start time to test their devices’ audio systems.

Submitting Questions at the Annual Meeting

Once online access to the Annual Meeting is open, stockholders may submit questions, if any, onwww.virtualshareholdermeeting.com/AMGN2020AMGN2022. To demonstrate proof of stock ownership, you will need to enter the control number provided with your Notice, proxy card, or voting instruction form to submit questions and vote at our Annual Meeting. Questions pertinent to meeting matters and that are submitted in accordance with our Rules of Conduct for the Annual Meeting will be answered during the meeting, subject to applicable time constraints.

Technical Assistance

Beginning immediately prior to the start of and during the virtual Annual Meeting, we will have a support team ready to assist stockholders with any technical difficulties they may have accessing or hearing the virtual meeting. If you encounter any difficulties accessing the virtual meeting, please call our support team at 800-586-1548 (U.S.) or 303-562-9288

Technical Assistance

Beginning immediately prior to the start of and during the virtual Annual Meeting, we will have a support team ready to assist stockholders with any technical difficulties they may have accessing or hearing the virtual meeting. If you encounter any difficulties accessing the virtual meeting, please call our support team at 844-976-0738 (U.S.) or 303-562-9301 (International).

 

 

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Other Matters

 

 

 

 

 

Other Matters

Stockholder Proposals for the 20212023 Annual Meeting

 

 

Stockholder Proposals and Director Nominees for Inclusion in our 20212023 Proxy Statement

Proposals Pursuant to Rule14a-8. Pursuant to Rule14a-8 under the Exchange Act, stockholders may present proper proposals for inclusion in our proxy statement and for consideration at our 20212023 annual meeting of stockholders. To be eligible for inclusion in our 20212023 proxy statement, your proposal must be received by our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799 or by facsimile number (805) 499-6751,no later than December 8, 2020,6, 2022, and must otherwise comply with Rule14a-8 under the Exchange Act. While our Board of Directors, or Board, will consider stockholder proposals, we reserve the right to omit from our proxy statement stockholder proposals that we are not required to include under the Exchange Act, including Rule14a-8.

Director Nominations Pursuant to Our Bylaws. Our Amended and Restated Bylaws of Amgen Inc., or Bylaws, permit an eligible stockholder, or group of up to 20 eligible stockholders, owning Amgen stock continuously for at least three years and shares representing an aggregate of at least 3% of our outstanding shares, to nominate and include in Amgen’s proxy materials director nominees constituting up to the greater of 20% of the Board or two directors, provided that the stockholder(s) and nominee(s) satisfy the requirements of the Bylaws (“Proxy Access”). To nominate a director pursuant to Proxy Access at the 20212023 annual meeting of stockholders, you must comply with all of the procedures, information requirements, qualifications and conditions set forth in our Bylaws. A fully compliant nomination notice must be received by us no earlier than November 8, 2020,6, 2022, and no later than December 8, 2020,6, 2022, assuming the date of the 20212023 annual meeting of stockholders is not more than thirty days before and not more than seventy days after the anniversary date of the 20202022 Annual Meeting of Stockholders, or Annual Meeting, and such nomination notice must be delivered to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799.91320-1799 or by facsimile number (805) 499-6751.

Stockholder Proposals and Nominees Brought at the 20212023 Annual Meeting Without Inclusion in our 20212023 Proxy Statement

Business Proposals and Nominations Pursuant to our Bylaws. To nominate a director or bring any other business before the stockholders at the 20212023 annual meeting of stockholders that will not be included in our 20212023 proxy statement pursuant to Rule14a-8 or the Proxy Access provisions of our Bylaws, you must comply with all of the procedures,

information requirements, qualifications and conditions set forth in our Bylaws. In addition, assuming the date of the 20212023 annual meeting of stockholders is not more than thirty days before and not more than seventy days after the anniversary date of the Annual Meeting, you must notify us in writing and such notice must be delivered to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799 or by facsimile number (805) 499-6751no earlier than January 19, 2021,17, 2023, and no later than February 18, 2021.16, 2023.

You may write to our Secretary at our principal executive offices at One Amgen Center Drive, Thousand Oaks, California 91320-1799 or by facsimile number (805) 499-6751, to deliver the notices discussed above and for a copy of the relevant Bylaw provisions regarding the requirements for making stockholder proposals and nominating director candidates pursuant to our Bylaws. Also, our Bylaws are filed with the Securities and Exchange Commission, or SEC, as an exhibit to our Exchange Act reports and can be accessed through the SEC’s EDGAR system.

The chairmanChair of the Annual Meeting has the sole authority to determine whether any nomination or other proposal has been properly brought before the meeting in accordance with our Bylaws. If we receive a proposal other than pursuant to Rule14a-8 or a nomination for the 20212023 annual meeting of stockholders, and such nomination or other proposal is not delivered within the time frame specified in our Bylaws, then the person(s) appointed by the Board and named in the proxies for the 20212023 annual meeting of stockholders may exercise discretionary voting power if a vote is taken with respect to that nomination or other proposal.

In addition to satisfying the foregoing requirements under our Bylaws, to comply with the universal proxy rules (once they become effective), stockholders who intend to solicit proxies in support of director nominees other than the Company’s nominees must provide notice that sets forth the information required by Rule 14a-19 under the Exchange Act no later than March 18, 2023.

2023 Annual Meeting

We intend to file a Proxy Statement and WHITE proxy card with the SEC in connection with its solicitation of proxies for our 2023 annual meeting of stockholders. Stockholders may obtain our Proxy Statement (and any amendments and supplements thereto) and other documents as and when filed by the Company with the SEC without charge from the SEC’s website at: www.sec.gov.(1)

 

(1)

Reference to the SEC website is not intended to function as a hyperlink and the information contained on the SEC website is not intended to be part of this proxy statement.

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Other Matters

Householding of Proxy Materials

 

 

The SEC has adopted rules that permit companies and intermediaries (such as brokers and banks) to satisfy the delivery requirements for proxy statements and annual reports with respect to two or more stockholders sharing the same address by delivering a single proxy statement addressed to those stockholders. This process, which is commonly referred to as “householding,” is also permissible under the General Corporation Law of the State of Delaware and potentially means extra convenience for stockholders and cost savings for companies.

This year, a number of brokers and banks with account holders who are our stockholders will be householding our proxy materials. A single Notice of Annual Meeting of Stockholders or proxy statement will be

delivered to multiple stockholders sharing an address unless contrary instructions have been received from the affected stockholders. Once you have received notice from your broker or bank that it will be householding communications to your address, householding will continue until you are notified otherwise or until you revoke your consent. If, at any time, you no longer wish to participate in householding and would prefer to receive a separate proxy statement and annual report, please notify your broker or bank.

Stockholders who currently receive multiple copies of the proxy statement at their address and would like to request householding of their communications should contact their broker or bank.

 

 

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Other Matters

No Incorporation by Reference

 

 

To the extent that this proxy statement is incorporated by reference into any other filing by us under the Securities Act of 1933 or the Exchange Act, the sections of this proxy statement entitled “Audit Committee Report” or “Compensation Committee Report” to the extent permitted by the rules of the SEC will not be deemed incorporated, unless specifically provided otherwise in such filing.

In addition, references to our website are not intended to function as a hyperlink and the information contained on our website is not intended to be part of this proxy statement. Information on our website, other than our proxy statement, Notice of Annual Meeting of Stockholders, and form of proxy, is not part of the proxy soliciting material and is not incorporated herein by reference.

 

Disclaimer

 

 

This proxy statement contains statements regarding future individual and Company performance targets and Company performance goals. These targets and Company performance goals are disclosed in the limited context of our compensation programs and should not be

understood to be statements of management’s expectations or estimates of results or other guidance. We specifically caution investors not to apply these statements to other contexts.

 

Forward-Looking Statements

 

 

This proxy statement contains forward-looking statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of collaborations, or potential collaborations, with any other company including(including BeiGene, Ltd., Kyowa-Kirin Co., Ltd., or any collaboration to manufacture therapeutic antibodies against COVID-19),the performance of Otezla® (apremilast) acquisition, including(including anticipated Otezla sales growth and the timing ofnon-GAAP EPS accretion,accretion), the Five Prime Therapeutics, Inc. acquisition, or the Teneobio, Inc. acquisition, as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems such as the ongoingCOVID-19 pandemic on our business, outcomes, progress, and other such estimates and results. Forward-looking statements involve significant risks and

uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including our most recent annual report on Form10-K and any subsequent periodic reports on Form10-Q and current reports on Form8-K. Unless otherwise noted, Amgen is providing this information as of March 26, 2020the date of this proxy statement and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise.

No forward-looking statement can be guaranteed and actual results may differ materially from those we project. Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions. In addition, sales of our products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including

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Other Matters

governments, private insurance plans and managed care providers and

may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. We or others could identify safety, side effects or manufacturing problems with our products, including our devices, after they are on the market. Our business may be impacted by government investigations, litigation and product liability claims. In addition, our business may be impacted by the adoption of new tax legislation or exposure to additional tax liabilities. If we fail to meet the compliance obligations in the corporate integrity agreement between us and the U.S. government, we could become subject to significant sanctions. Further, while we routinely obtain patents for our products and technology, the protection offered by our patents and patent applications may be challenged, invalidated or circumvented by our competitors, or we may fail to prevail in present and future intellectual property litigation. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico, and also depend on third parties for a portion of our manufacturing activities, and limits on supply may constrain sales of certain of our current products and product candidate development. An outbreak of disease or similar public health threat, such asCOVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect on the supply of materials for our manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product sales, business and results of operations. We rely on collaborations with third parties for the development of some of our product candidates and for the commercialization and sales of some of our

commercial products. In addition, we compete with other companies with respect to many of our marketed products as well as for the discovery and development of new products. Discovery or identification of new product candidates or development of new indications for existing products cannot be

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Other Matters

guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, some raw materials, medical devices and component parts for our products are supplied by sole third-party suppliers. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. The discovery of significant problems with a product similar to one of our products that implicate an entire class of products could have a material adverse effect on sales of the affected products and on our business and results of operations. Our efforts to collaborate

with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful. A breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of our systems and our data. Our stock price is volatile and may be affected by a number of events. Our business and operations may be negatively affected by the failure, or perceived failure, of achieving our environmental, social and governance objectives. The effects of global climate change and related natural disasters could negatively affect our business and operations. Global economic conditions may magnify certain risks that affect our business. Our business performance could affect or limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our common stock. We may not be able to access the capital and credit markets on terms that are favorable to us, or at all.

 

Other Matters

 

The Board knows of no matters other than those listed in the attached Notice of Annual Meeting of Stockholders that are likely to be brought before the Annual Meeting. However, if any other matter properly comes before the Annual Meeting, the persons named on the enclosed proxy card will vote the proxy in accordance with their best judgment on such matter.

By Order of the Board of Directors

 

 

LOGOLOGO

Jonathan P. Graham

Secretary

April 7, 20205, 2022

 

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Appendix A

 

 

 

 

 

Appendix A

Amgen Inc. Board of Directors

Guidelines for Director Qualifications and Evaluations

 

These guidelines set forth (1) the minimum qualifications that the Governance and Nominating Committee of the Board of Directors (the “Committee”) of Amgen Inc. (“Amgen”) believes are important for directors to possess, and (2) a description of the Committee’s process for identifying and evaluating nominees for director, including nominees recommended by stockholders. These guidelines are only guidelines and may be waived and/or changed by the Committee and/or the Board of Directors as appropriate.

1. Candidate Qualifications

In seeking individuals to join the Board of Directors or to fill director vacancies on the Board of Directors, the Committee considers the following to be minimum qualifications that a candidate must possess:

 

Demonstrated breadth and depth of management and leadership experience, preferably in a senior leadership role in a large or recognized organization;

 

Financial and/or business acumen or relevant industry or scientific experience;

 

Integrity and high ethical standards;

 

Sufficient time to devote to Amgen’s business as a member of the Board;

 

Ability to oversee, as a director, Amgen’s business and affairs for the benefit of Amgen’s stockholders;

 

Ability to comply with the Board’s Code of Conduct; and

 

Demonstrated ability to think independently and work collaboratively.

In addition, the Committee may consider the following where necessary and appropriate:

 

A candidate’s independence, as defined by The NASDAQ Stock Market, Inc.;

 

A candidate’s ability to satisfy the composition requirements for the Audit Committee and the Compensation and Management Development Committee;

 

Maintaining a Board that reflects diversity; and

 

The Board’s overall size, structure and composition.

2. Candidate Identification and Evaluation Process

(a) For purposes of identifying nominees for the Board of Directors, the Committee relies on professional and personal contacts of the Committee, other members of the Board of Directors and senior management, as well as candidates recommended by independent search firms retained by the Committee from time to time. The Committee also will consider candidates recommended by stockholders. Any director nominations submitted by stockholders will be evaluated in the same manner that nominees suggested by Board members, management or other parties are evaluated.

(b) In evaluating potential candidates, the Committee will determine whether the candidate is qualified for service on the Board of Directors by evaluating the candidate under the guidelines set forth above and by determining if any individual candidate suits the Committee’s and the Board of Director’s overall objectives at the time the candidate is being evaluated.

 

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Appendix B

 

 

 

 

 

Appendix B

Reconciliations of GAAP toNon-GAAP Measures

 

Amgen Inc.

GAAP toNon-GAAP Reconciliations

(Dollars in millions)

(Unaudited)

 

 Years ended December 31,  Years ended December 31, 
 

 

  

 

 
          2019                     2018                     2017                    2021                     2020                     2019          

GAAP cost of sales

   $4,356        $4,101        $4,069       $6,454        $6,159        $4,356    

Adjustments to cost of sales:

          

Acquisition-related expenses (a)

 (1,291)       $(1,099)       $(1,126)    (2,443)      (2,797)      (1,291)   

Certain net charges pursuant to our restructuring initiatives

  —        $(1)       $—    

Other

 (17)      —       —    
 

 

   

 

   

 

  

 

   

 

   

 

 

Total adjustments to cost of sales

 (1,291)                (1,100)                (1,126)    (2,460)      (2,797)      (1,291)   
 

 

   

 

   

 

  

 

   

 

   

 

 

Non-GAAP cost of sales

   $          3,065        $3,001        $2,943       $3,994        $3,362        $3,065    
 

 

   

 

   

 

  

 

   

 

   

 

 

GAAP cost of sales as a percentage of product sales

 19.6%    18.2%    18.7% 

GAAP cast of sales as a percentage of product sales

 26.6%    25.4%    19.6% 

Acquisition-related expenses (a)

 -5.8       -4.9       -5.2     -10.1       -11.5       -5.8    

Certain net charges pursuant to our restructuring initiatives

 0.0       0.0       0.0    

Other

 -0.1       0.0       0.0    
 

 

   

 

   

 

  

 

   

 

   

 

 

Non-GAAP cost of sales as a percentage of product sales

 13.8%    13.3%    13.5%  16.4%    13.9%    13.8% 
 

 

   

 

   

 

  

 

   

 

   

 

 

GAAP research and development expenses

   $4,116        $3,737        $3,562       $4,819        $4,207        $4,116    

Adjustments to research and development expenses:

          

Acquisition-related expenses(a)

 (87)      (78)      (77)   

Certain net charges pursuant to our restructuring initiatives

 (2)      (2)      (3)   

Licensing- and acquisition-related expenses (b)

 (523)      (120)      (87)   

Certain net charges pursuant to our cost savings and other restructuring initiatives

  —       (2)      (2)   
 

 

   

 

   

 

  

 

   

 

   

 

 

Total adjustments to research and development expenses

 (89)      (80)      (80)    (523)      (122)      (89)   
 

 

   

 

   

 

  

 

   

 

   

 

 

Non-GAAP research and development expenses

   $4,027        $3,657        $3,482       $          4,296        $          4,085        $          4,027    
 

 

   

 

   

 

  

 

   

 

   

 

 

GAAP research and development expenses as a percentage of product sales

 18.5%    16.6%    16.3%  19.8%    17.4%    18.5% 

Acquisition-related expenses(a)

 -0.4       -0.4       -0.3    

Certain net charges pursuant to our restructuring initiatives

 0.0       0.0       0.0    

Licensing- and acquisition-related expenses (b)

 -2.1       -0.5       -0.4    

Certain net charges pursuant to our cost savings and other restructuring initiatives

 0.0       0.0       0.0    
 

 

   

 

   

 

  

 

   

 

   

 

 

Non-GAAP research and development expenses as a percentage of product sales

 18.1%    16.2%    16.0%  17.7%    16.9%    18.1% 
 

 

   

 

   

 

 

GAAP acquired IPR&D

   $1,505        $—        $—    

Adjustments to acquired IPR&D:

     

Five Prime acquisition IPR&D expense

 (1,505)      —       —    
 

 

   

 

   

 

 

Non-GAAP acquired IPR&D

   $—        $—        $—    
 

 

   

 

   

 

 

GAAP acquired IPR&D expenses as a percentage of product sales

 6.2%    0.0%    0.0% 

Five Prime acquisition IPR&D expense

 -6.2       0.0       0.0    
 

 

   

 

   

 

 

Non-GAAP acquired IPR&D expenses as a percentage of product sales

 0.0%    0.0%    0.0% 
 

 

   

 

   

 

  

 

   

 

   

 

 

GAAP selling, general and administrative expenses

   $5,150        $5,332        $4,870       $5,368        $5,730        $5,150    

Adjustments to selling, general and administrative expenses:

          

Acquisition-related expenses(a)

 (38)      (84)      (99)    (87)      (85)      (38)   

Certain net charges pursuant to our restructuring initiatives

 1       (16)      (2)     —       —       1    

Other

  —       —       (3)    (16)      (2)      —    
 

 

   

 

   

 

  

 

   

 

   

 

 

Total adjustments to selling, general and administrative expenses

 (37)      (100)      (104)    (103)      (87)      (37)   
 

 

   

 

   

 

  

 

   

 

   

 

 

Non-GAAP selling, general and administrative expenses

   $5,113        $5,232        $4,766       $5,265        $5,643        $5,113    
 

 

   

 

   

 

  

 

   

 

   

 

 

GAAP selling, general and administrative expenses as a percentage of product sales

 23.2%    23.7%    22.3% 

Acquisition-related expenses(a)

 -0.2       -0.4       -0.4    

Certain net charges pursuant to our restructuring initiatives

 0.0       -0.1       0.0    

Other

 0.0       0.0       0.0    
 

 

   

 

   

 

 

Non-GAAP selling, general and administrative expenses as a percentage of product sales

 23.0%    23.2%    21.9% 
 

 

   

 

   

 

 

See footnotes on page B-3.B-5.

 

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Appendix B

 

 

 

 

 

  Years ended December 31, 
  

 

 
           2019                     2018                     2017          

GAAP operating expenses

   $13,688        $13,484        $12,876    

Adjustments to operating expenses:

     

Adjustments to cost of sales

  (1,291)      (1,100)      (1,126)   

Adjustments to research and development expenses

  (89)      (80)      (80)   

Adjustments to selling, general and administrative expenses

  (37)      (100)      (104)   

Certain net charges pursuant to our restructuring initiatives(b)

  (44)      7       (83)   

Certain other expenses

  —       (25)      —    

Acquisition-related adjustments(c)

  (22)      (296)      (292)   
 

 

 

   

 

 

   

 

 

 

Total adjustments to operating expenses

  (1,483)      (1,594)      (1,685)   
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating expenses

   $          12,205        $          11,890        $          11,191    
 

 

 

   

 

 

   

 

 

 

GAAP operating income

   $9,674        $10,263        $9,973    

Adjustments to operating expenses

  1,483       1,594       1,685    
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating income

   $11,157        $11,857        $11,658    
 

 

 

   

 

 

   

 

 

 

GAAP operating income as a percentage of product sales

  43.6%    45.5%    45.8% 

Adjustments to cost of sales

  5.8       4.9       5.2    

Adjustments to research and development expenses

  0.4       0.4       0.3    

Adjustments to selling, general and administrative expenses

  0.2       0.5       0.4    

Certain net charges pursuant to our restructuring initiatives

  0.2       0.0       0.4    

Certain other expenses

  0.0       0.0       0.0    

Acquisition-related adjustments(c)

  0.0       1.3       1.4    
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating income as a percentage of product sales

  50.2%    52.6%    53.5% 
 

 

 

   

 

 

   

 

 

 

GAAP interest and other income, net

   $753        $674        $928    

Adjustments to other income (d)

  —       (68)      —    
 

 

 

   

 

 

   

 

 

 

Non-GAAP interest and other income, net

   $753        $606        $928    
 

 

 

   

 

 

   

 

 

 

GAAP income before income taxes

   $9,138        $9,545        $9,597    

Adjustments to operating expenses

  1,483       1,594       1,685    

Adjustments to other income (d)

  —       (68)      —    
 

 

 

   

 

 

   

 

 

 

Non-GAAP income before income taxes

   $10,621        $11,071        $11,282    
 

 

 

   

 

 

   

 

 

 

GAAP provision for income taxes

   $1,296        $1,151        $7,618    

Adjustments to provision for income taxes:

     

Income tax effect of the above adjustments(e)

  329       362       538    

Other income tax adjustments(f)

  (32)      (15)      (6,120)   
 

 

 

   

 

 

   

 

 

 

Total adjustments to provision for income taxes

  297       347       (5,582)   
 

 

 

   

 

 

   

 

 

 

Non-GAAP provision for income taxes

   $1,593        $1,498        $2,036    
 

 

 

   

 

 

   

 

 

 

GAAP tax as a percentage of income before taxes

  14.2%    12.1%    79.4% 

Adjustments to provision for income taxes:

     

Income tax effect of the above adjustments(e)

  1.1       1.6       -7.1    

Other income tax adjustments(f)

  -0.3       -0.2       -54.3    
 

 

 

   

 

 

   

 

 

 

Total adjustments to provision for income taxes

  0.8       1.4       -61.4    
 

 

 

   

 

 

   

 

 

 

Non-GAAP tax as a percentage of income before taxes

  15.0%    13.5%    18.0% 
 

 

 

   

 

 

   

 

 

 

GAAP net income

   $7,842        $8,394        $1,979    

Adjustments to net income:

     

Adjustments to income before income taxes, net of the income tax effect

  1,154       1,164       1,147    

Other income tax adjustments(f)

  32       15       6,120    
 

 

 

   

 

 

   

 

 

 

Total adjustments to net income

  1,186       1,179       7,267    
 

 

 

   

 

 

   

 

 

 

Non-GAAP net income

   $9,028        $9,573        $9,246    
 

 

 

   

 

 

   

 

 

 

  Years ended December 31, 
  

 

 
           2021                     2020                    2019          

GAAP selling, general and administrative expenses as a percentage of product sales

  22.1%    23.6%    23.2% 

Acquisition-related expenses (a)

  -0.4       -0.3       -0.2    

Certain net charges pursuant to our restructuring initiatives

  0.0       0.0       0.0    

Other

  0.0       0.0       0.0    
 

 

 

   

 

 

   

 

 

 

Non-GAAP selling, general and administrative expenses as a percentage of product sales

  21.7%    23.3%    23.0% 
 

 

 

   

 

 

   

 

 

 

GAAP operating expenses

   $          18,340        $          16,285        $          13,688    

Adjustments to operating expenses:

     

Adjustments to cost of sales

  (2,460)      (2,797)      (1,291)   

Adjustments to research and development expenses

  (523)      (122)      (89)   

Adjustments to acquired IPR&D

  (1,505)      —       —    

Adjustments to selling, general and administrative expenses

  (103)      (87)      (37)   

Certain net charges pursuant to our cost savings and other restructuring initiatives

  (130)      5       (44)   

Certain other expenses (c)

  (64)      (194)      (22)   
 

 

 

   

 

 

   

 

 

 

Total adjustments to operating expenses

  (4,785)      (3,195)      (1,483)   
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating expenses

   $13,555        $13,090        $12,205    
 

 

 

   

 

 

   

 

 

 

GAAP operating income

   $7,639        $9,139        $9,674    

Adjustments to operating expenses

  4,785       3,195       1,483    
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating income

   $12,424        $12,334        $11,157    
 

 

 

   

 

 

   

 

 

 

GAAP operating income as a percentage of product sales

  31.4%    37.7%    43.6% 

Adjustments to cost of sales

  10.2       11.5       5.8    

Adjustments to research and development expenses

  2.1       0.5       0.4    

Adjustments to acquired IPR&D

  6.2       0.0       0.0    

Adjustments to selling, general and administrative expenses

  0.4       0.4       0.2    

Certain net charges pursuant to our cost savings and other restructuring initiatives

  0.5       0.0       0.2    

Certain other expenses (c)

  0.3       0.8       0.0    
 

 

 

   

 

 

   

 

 

 

Non-GAAP operating income as a percentage of product sales

  51.1%    50.9%    50.2% 
 

 

 

   

 

 

   

 

 

 

GAAP other income, net

   $259        $256        $753    

Adjustments to other income (expense), net:

     

Adjustments to other income (d)

  (248)      37       —    
 

 

 

   

 

 

   

 

 

 

Non-GAAP other income (expense), net

   $11        $293        $753    
 

 

 

   

 

 

   

 

 

 

GAAP income before income taxes

   $6,701        $8,133        $9,138    

Adjustments to operating expenses

  4,785       3,195       1,483    

Adjustments to other income (d)

  (248)      37       —    
 

 

 

   

 

 

   

 

 

 

Non-GAAP income before income taxes

   $11,238        $11,365        $10,621    
 

 

 

   

 

 

   

 

 

 

GAAP provision for income taxes

   $808        $869        $1,296    

Adjustments to provision for income taxes:

     

Income tax effect of the above adjustments (e)

  630       634       329    

Other income tax adjustments (f)

  3       67       (32)   
 

 

 

   

 

 

   

 

 

 

Total adjustments to provision for income taxes

  633       701       297    
 

 

 

   

 

 

   

 

 

 

Non-GAAP provision for income taxes

   $1,441        $1,570        $1,593    
 

 

 

   

 

 

   

 

 

 

See footnotes on page B-3.B-5.

 

B-2    LOGO  ï 20202022 Proxy Statement


    

 

 

 

 

Appendix B

 

 

 

 

 

  Years ended December 31, 
  

 

 
           2021                     2020                    2019          

GAAP tax as a percentage of income before taxes

  12.1%    10.7%    14.2% 

Adjustments to provision for income taxes:

     

Income tax effect of the above adjustments (e)

  0.7       2.5       1.1    

Other income tax adjustments (f)

  0.0       0.6       -0.3    
 

 

 

   

 

 

   

 

 

 

Total adjustments to provision for income taxes

  0.7       3.1       0.8    
 

 

 

   

 

 

   

 

 

 

Non-GAAP tax as a percentage of income before taxes

  12.8%    13.8%    15.0% 
 

 

 

   

 

 

   

 

 

 

GAAP net income

   $5,893        $7,264        $7,842    

Adjustments to net income:

     

Adjustments to income before income taxes, net of the income tax effect

  3,907       2,598       1,154    

Other income tax adjustments (f)

  (3)      (67)      32    
 

 

 

   

 

 

   

 

 

 

Total adjustments to net income

  3,904       2,531       1,186    
 

 

 

   

 

 

   

 

 

 

Non-GAAP net income

   $            9,797        $            9,795        $            9,028    
 

 

 

   

 

 

   

 

 

 

See footnotes on page B-5.

LOGO ï 2022 Proxy StatementB-3


Appendix B

Amgen Inc.

GAAP toNon-GAAP Reconciliations

(In millions, exceptper-share data)

(Unaudited)

The following table presentstables present the computations for GAAP andnon-GAAP diluted earnings per share.

 

  Years ended December 31,   Years ended December 31, 
  2019   2018   2017   2021   2020   2019 
  GAAP   Non-GAAP   GAAP   Non-GAAP   GAAP   Non-GAAP   GAAP   Non-GAAP   GAAP   Non-GAAP   GAAP   Non-GAAP 

Net income

    $     7,842     $     9,028     $     8,394     $     9,573     $     1,979     $     9,246 

Net Income

    $     5,893     $     9,797     $     7,264     $     9,795     $     7,842     $     9,028 

Shares

                        

Weighted-average shares for basic EPS

   605    605    661    661    731    731    570    570    586    586    605    605 

Effect of dilutive securities

   4    4    4    4    4    4    3    3    4    4    4    4 
  

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

 

Weighted-average shares for diluted EPS

   609    609    665    665    735    735    573    573    590    590    609    609 
  

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

 

Diluted earnings per share

    $12.88     $14.82     $12.62     $14.40     $2.69     $12.58 

Diluted earnings per shares

    $10.28     $17.10     $12.31     $16.60     $12.88     $14.82 
  

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

   

 

 

The following table presentstables present the computations for invested capital and Return on Invested capital under the terms of the 2019-2021 Performance Period.

   At December 31,   Average 
   2021   2020   2021 

Total assets

    $     61,165        $     62,948        $     62,057    

less Cash, cash equivalents and marketable securities

   (8,037)      (10,647)      (9,342)   

less Total current liabilities

   (12,184)      (11,653)      (11,919)   
  

 

 

   

 

 

   

 

 

 

Invested capital

    $40,944        $40,648        $40,796    
  

 

 

   

 

 

   

 

 

 
           2021
Average
 

2021 Non-GAAP Operating Income (per above)

 

      $12,424    

After-tax factor (100% less Non-GAAP tax rate per above)

 

   87.2% 
      

 

 

 

Non-GAAP Net Operating Income after tax

 

      $10,834    
    

 

 

 

2021 Return on Invested capital (Net Operating Income after tax divided by Average Invested capital)

 

   26.6% 
  

 

 

 

  At December 31,  Average
2020
  At December 31,  Average
2019
 
  2020  2019  2019  2018 

Total assets

   $     62,948       $     59,707       $     61,328       $     59,707       $     66,416       $     63,062    

less Cash, cash equivalents and marketable securities

  (10,647)     (8,911)     (9,779)     (8,911)     (29,304)     (19,108)   

less Total current liabilities

  (11,653)     (12,835)     (12,244)     (12,835)     (13,488)     (13,162)   
 

 

 

  

 

 

  

 

 

  

 

 

  

 

 

  

 

 

 

Invested capital

   $40,648       $37,961       $39,305       $37,961       $23,624       $30,793    
 

 

 

  

 

 

  

 

 

  

 

 

  

 

 

  

 

 

 
        2020        2019 

Non-GAAP Operating Income (per above)

     $12,334         $11,157    

After-tax factor (100% less Non-GAAP tax rate per above)

    86.2%     85.0% 
   

 

 

    

 

 

 

Non-GAAP Net Operating income after tax

     $10,632         $9,483    
   

 

 

    

 

 

 

Return on Invested capital (Net Operating Income after tax divided by Average Invested capital)

    27.1%     30.8% 
   

 

 

    

 

 

 

See footnotes on page B-5.

B-4    LOGO ï 2022 Proxy Statement


Appendix B

The following tables present the computations for Invested capital and Return on Invested capital.capital under the terms of the 2020-2022 and 2021-2023 Performance Periods.

 

   At December 31,     
   2019   2018   2019 Average 

Total assets

    $     59,707     $     66,416     $     63,062    

lessCash, cash equivalents and marketable securities

   (8,911   (29,304   (19,108)   

less Total current liabilities

   (12,835   (13,488   (13,162)   
  

 

 

   

 

 

   

 

 

 

Invested capital

    $37,961     $23,624     $30,792.5    
  

 

 

   

 

 

   

 

 

 

2019Non-GAAP Operating Income (per above)

        $11,157    

2019After-tax factor (100%lessNon-GAAP tax rate per above)

 

     85.0% 
    

 

 

 

2019Non-GAAP Net Operating income after tax

 

    $9,483    
  

 

 

 

2019 Return on Invested capital (Net Operating Income after taxdivided by Average Invested capital)

 

   30.8% 
  

 

 

 
   12/31/20   3/31/21   6/30/21   9/30/21   12/31/21 

Total assets

    $     62,948        $     62,539        $     59,773        $     64,993        $     61,165    

less Total current liabilities

   (11,653)      (12,869)      (14,585)      (14,842)      (12,184)   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Invested capital

    $51,295        $49,670        $45,188        $50,151        $48,981    
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

   

 

Average Invested Capital for Quarter Ended

   Average of
Quarterly
Averages
2021
 
   3/31/21   6/30/21   9/30/21   12/31/21 

Average Invested capital

    $     50,483     $     47,429     $     47,670     $     49,566   $     48,787     

2021 Non-GAAP Operating Income (per above)

          $12,424     

2021 After-tax factor (100% less Non-GAAP tax rate per above)

           87.2% 
          

 

 

 

2021 Non-GAAP Net Operating Income after tax

 

    $10,834     
          

 

 

 

2021 Return on Invested capital (Net Operating Income after tax divided by Average Invested capital)

 

   22.2% 
          

 

 

 

   12/31/19   3/31/20   6/30/20   9/30/20   12/31/20 

Total assets

    $     59,707          $     61,669          $     65,011          $     64,637          $     62,948      

less Total current liabilities

   (12,835)        (11,827)        (10,523)        (9,953)        (11,653)     
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Invested capital

    $     46,872          $     49,842          $     54,488          $     54,684          $     51,295      
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

   Average Invested Capital for Quarter Ended   Average of
Quarterly
Averages
 
   3/31/20   6/30/20   9/30/20   12/31/20   2020 

Average Invested capital

    $     48,357     $     52,165     $     54,586     $     52,990   $     52,024     

2020 Non-GAAP Operating Income (per above

          $12,334     

2020 After-tax factor (100% less Non-GAAP tax rate per above)

           86.2% 
          

 

 

 

2020 Non-GAAP Net Operating income after tax

          $10,632     
          

 

 

 

2020 Return on Invested capital (Net Operating Income after tax divided by Average Invested capital)

 

   20.4% 
          

 

 

 

 

(a)

The adjustments related primarily to noncash amortization of intangible assets acquired infrom business combinations.acquisitions.

(b)

ForThe adjustments for the yearstwelve months ended December 31, 2019 and 2017, the adjustments2021, related primarily to severance expenses associated with our restructuring activities.licensing-related expense from the upfront payment to Kyowa Kirin Co., Ltd. and noncash amortization of intangibles from business acquisitions. The adjustments for the remaining years related primarily to noncash amortization of intangible assets acquired in business combinations.

(c)

For the years ended December 31, 20182021 and 2017,2020, the adjustments related primarily to impairment of intangible assets acquired in business combinations.legal matters.

(d)

Effective January 2021, we began to exclude the gains and losses on our investments in equity securities from our non-GAAP measures that are recorded to Other income, net. For the year ended December 31, 2018,2021, the adjustmentadjustments related to equity Investment gains, partially offset by the amortization of the basis difference from our BelGene equity method investment. For the year ended December 31, 2020, the adjustments related to the netamortization of the basis difference from our BelGene equity method Investment, partially offset by a gain associated with the Kirin-Amgen, Inc. acquisition.from legal judgment proceeds.

(e)

The tax effect of the adjustments between our GAAP andnon-GAAP results takes into account the tax treatment and related tax rate(s) that apply to each adjustment in the applicable tax jurisdiction(s). Generally, this results in a tax impact at the U.S. marginal tax rate for certain adjustments, including the majority of amortization of intangible assets, whereas the tax impact of other adjustments, including restructuring initiatives, depends on whether the amounts are deductible in the respective tax jurisdictions and the applicable tax rate(s) in those jurisdictions. Acquired IPR&D expense from the Five Prime acquisition was not tax deductible. Due to these factors, the effective tax rates for the adjustments to our GAAP income before income taxes, for year ended December 31, 2019,2021, was 13.9% compared to 19.6% and 22.2% compared 23.7%for 2020 and 31.9% for 2018 and 2017,2019, respectively.

(f)

For the year ended December 31, 2017, the adjustmentThe adjustments related primarily to the impact of U.S. Corporate tax reform, including the repatriation tax on accumulated foreign earningscertain acquisition items and the remeasurement of certain net deferred and other tax liabilities.prior period items excluded from GAAP earnings.

 

LOGO  ï 20202022 Proxy Statement    B-3B-5


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AMGEN INC.

ONE AMGEN CENTER DRIVE

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AMGEN INC.     
  
  

The Board of Directors recommends you vote “FOR” each

listed nominee in item #1.    
  

1.

To elect eleventwelve directors to the Board of Directors of Amgen Inc. for a term of office expiring at the 20212023 annual meeting of stockholders. The nominees for election to the Board of Directors are:

 

For

Against

Abstain

 

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Abstain

 
    
 1a.

    1a.     Dr. Wanda M. Austin

 

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 ForAgainstAbstain
  

1b.

Mr. Robert A. Bradway

 

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1k.     Dr. Ronald D. Sugar

  

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Dr. Brian J. Druker

 

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1l.     Dr. R. Sanders Williams

 
 

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    1d.     Mr. Robert A. Eckert

 

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The Board of Directors recommends you vote “FOR” each

of items #2 and #3.

 
1e.Mr. Greg C. Garland
 

    1e.     Mr. Greg C. Garland

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    1f.      Mr. Charles M. Holley, Jr.

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2.  

Advisory vote to approve our executive compensation.
1f.Mr. Fred Hassan
1g.

Mr. Charles M. Holley, Jr.

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    1g.     Dr. S. Omar Ishrak

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To ratify the selection of Ernst & Young LLP as our independent registered public accountants for the fiscal year ending December 31, 2020.
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 1h.

    1h.     Dr. Tyler Jacks

 

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1i.Ms. Ellen J. Kullman
 The Board of Directors recommends you vote “AGAINST” the Stockholder Proposal in item #4.
 4.     Stockholder proposal to require an independent board chair.
 
  

    1i.      Ms. Ellen J. Kullman

 

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NOTE:Such other business as may properly come before the meeting or any continuation, postponement, or adjournment thereof.

 
 

 

    1j.      Ms. Amy E. Miles

 

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IMPORTANT NOTICE REGARDING THE AVAILABILITY OF PROXY MATERIALS

FOR THE STOCKHOLDER MEETING TO BE HELD ON MAY 19, 202017, 2022:

The Notice of 20202022 Annual Meeting of Stockholders, Proxy Statement, Form Proxy Card and 20192021 Annual Report are

available at www.proxyvote.com.

In light of the ongoing developments related to the COVID-19 pandemic, theThe Amgen Inc. 20202022 Annual Meeting of Stockholders will be held solely by remote communication via the Internetat www.virtualshareholdermeeting.com/AMGN2020.

AMGN2022. While you will not be able to attend the Annual Meeting in person,stockholders will, to the extent possible, be afforded the same rights and opportunities to participate at the virtualmeetingsimilarly to how they would participate at an in-person meeting.

This Proxy Card will be voted as specified or, if no choice is specified, will be voted FOR the election of each of the named director nominees, FOR the advisory vote to approve our executive compensation, and FOR ratification of the selection of Ernst & Young LLP as our independent registered public accountant, and AGAINST the Stockholder Proposal.

accountants.

As of the date hereof, the undersigned hereby acknowledges receipt of the 20202022 Proxy Statement and accompanying Notice of 20202022 Annual Meeting of Stockholders to be held on May 19, 2020,17, 2022, Form Proxy Card, and the 20192021 Annual Report.

In their discretion, the Proxy Holders (as defined below) are authorized to vote upon such other matters as may properly come before the 20202022 Annual Meeting of Stockholders and at any continuation, postponement, or adjournment thereof. The Board of Directors, at present, knows of no other business to be presented at the 20202022 Annual Meeting of Stockholders.

By signing this proxy you revoke all prior proxies. This proxy will be governed by the laws of the State of Delaware and federal securities laws.

— — — — — — — — — — — — —  — — — — — — — — — — — — — — — — — — — —  — — — — — — — — — — — — — — — — — — 

D72126-P66388          

 

AMGEN INC.

D08476-Z76923

ONE AMGEN CENTER DRIVE, THOUSAND OAKS, CA 91320-1799

PROXY SOLICITED BY THE BOARD OF DIRECTORS

FOR THE 2022 ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON MAY 17, 2022

Robert A. Bradway, Peter H. Griffith, and Jonathan P. Graham (the “Proxy Holders”), or any of them, each with the power of substitution, hereby are authorized to represent the undersigned, with all powers which the undersigned would possess if personally present, to vote the shares of Amgen Inc. Common Stock of the undersigned at the 2022 Annual Meeting of Stockholders of Amgen Inc., to be held on Tuesday, May 17, 2022, at 11:00 A.M., Pacific Time, by remote communication via the internet at www.virtualshareholdermeeting.com/AMGN2022, and at any continuation, postponement, or adjournment of that meeting, upon and in respect of the following matters and in accordance with the following instructions, with discretionary authority as to any and all other business that may properly come before the meeting.

You are encouraged to specify your choices by marking the appropriate boxes, SEE REVERSE SIDE, but you need not mark any boxes if you wish to vote in accordance with the Board of Directors’ recommendations.

PLEASE MARK, SIGN, DATE, AND RETURN PROMPTLY USING THE ENCLOSED ENVELOPE.

(Continued and to be signed on reverse side)

 

AMGEN INC.

ONE AMGEN CENTER DRIVE, THOUSAND OAKS, CA 91320-1799
PROXY SOLICITED BY THE BOARD OF DIRECTORS

FOR THE 2020 ANNUAL MEETING OF STOCKHOLDERS TO BE HELD ON MAY 19, 2020

Robert A. Bradway, Peter H. Griffith and Jonathan P. Graham (the “Proxy Holders”), or any of them, each with the power of substitution, hereby are authorized to represent the undersigned, with all powers which the undersigned would possess if personally present, to vote the shares of Amgen Inc. Common Stock of the undersigned at the 2020 Annual Meeting of Stockholders of Amgen Inc., to be held on Tuesday, May 19, 2020, at 11:00 A.M., Pacific Time, by remote communication via the internet at www.virtualshareholdermeeting.com/AMGN2020, and at any continuation, postponement, or adjournment of that meeting, upon and in respect of the following matters and in accordance with the following instructions, with discretionary authority as to any and all other business that may properly come before the meeting.

You are encouraged to specify your choices by marking the appropriate boxes, SEE REVERSE SIDE, but you need not mark any boxes if you wish to vote in accordance with the Board of Directors’ recommendations.

PLEASE MARK, SIGN, DATE, AND RETURN PROMPTLY USING THE ENCLOSED ENVELOPE.

(Continued and to be signed on reverse side)


SAMPLE

THIS IS A VOTING INSTRUCTION FORM.

You are receiving this voting instruction form because you hold shares in the above Security. You have the right to vote on proposals being presented at the upcoming Annual Meeting to be held on

VOTING INSTRUCTIONS

X

D10017-P36263 

THIS VOTING INSTRUCTION FORM IS VALID ONLY WHEN SIGNED AND DATED. PLEASE USE BLUE OR BLACK INK AND RETURN ONLY THE BOTTOM PORTION.

Please check this box if you plan to attend the Meeting online and vote these shares☐ 

The Board of Directors recommends you vote “FOR” each listed nominee in item #1.

1.  

To elect eleven directors to the Board of Directors of Amgen Inc. for a term of office expiring at the 2021 annual meeting of stockholders. The nominees for election to the Board of Directors are:

For

Against

Abstain

��

The Board of Directors recommends you vote “FOR” each of items #2 and #3.

For 

Against

Abstain

1a.Dr. Wanda M. Austin2.Advisory vote to approve our executive compensation.
1b.Mr. Robert A. Bradway

3.

To ratify the selection of Ernst & Young LLP as our independent registered public accountants for the fiscal year ending December 31, 2020.

1c.Dr. Brian J. Druker

1d.Mr. Robert A. Eckert
1e.

Mr. Greg C. Garland

The Board of Directors recommends you vote “AGAINST” the Stockholder Proposal in item #4.

For AgainstAbstain
1f.Mr. Fred Hassan
1g.Mr. Charles M. Holley, Jr.

4.   

Stockholder proposal to require an independent board chair.

1h.Dr. Tyler Jacks

NOTE:Such other business as may properly come before the meeting or any continuation, postponement, or adjournment thereof.

1i.Ms. Ellen J. Kullman
1j.Dr. Ronald D. Sugar 
1k.Dr. R. Sanders Williams
YesNo
HOUSEHOLDING ELECTION- Please indicate if you consent to receive certain future investor communications in a single package per household.

Signature [PLEASE SIGN WITHIN BOX]

Date